- Jocelyn Jee Esien - Carla Langer
- Phyllida Law - Bea Nelson-Stanley
- Silas Carson - Uvlavad Kudlak (voice)
- Jane Asher - Andrea Yates
- David Tennant - The Doctor
- Samantha Bond - Wormwood
- Juliet Cowan - Chrissie Jackson
- Jessica Ashworth - Young Sarah Jane
- Nicholas Courtney - Sir Alistair Gordon Lethbridge-Stewart
- Bradley Walsh - The Pied Piper
- Doreen Mantle - Mrs Randall
- Christopher Pizzey - Eddie Smith
- Beth Goddard - Sister Helena
- Jamie Davis - Davey
- Lachele Carl - Trinity Wells
- Konnie Huq - Blue Peter Presenter
- Gethin Jones - Blue Peter Presenter
- Mina Anwar - Gita Chandra
- Fiona Hampton - Lady Matilda
- Katy Manning - Jo Jones
- Finn Jones - Santiago Jones
- Laila Rouass - Colonel Tia Karim
- David Bradley - Shansheeth Blue (voice)
- Matt Smith - The Doctor
- John Leeson - K9 (voice)
- Tom Wlaschiha - Lt. Koenig
- Eddie Marsan - Mr. White
- Jimmy Vee - Graske
- Jimmy Vee - Korst Gogg Thek Lutiven-Day Slitheen
- Jimmy Vee - Groske
- Rosanna Lavelle - Barbara Smith
- Julian Bleach - The Nightmare Man
- Suranne Jones - Mona Lisa
- Paul Marc Davis - The Trickster
- Russ Abbot - Martin Trueman
- Cyril Nri - The Shopkeeper
- Joseph Millson - Alan Jackson
- Anthony O'Donnell - Kaagh
- Dan Starkey - Plark
- James Dreyfus - Harrison
- Christine Stephen-Daly - Miss Myers
- Julie Graham - Ruby White
- Julie Gardner
- Phil Collinson
- Piers Wenger
- Susie Liggat
- Nikki Wilson
- Russell T Davies
Eddie Marsan hace el papel de Mr. White.
Elisabeth Sladen interpreta a Sarah Jane Smith en la serie.
Tommy Knight interpreta a Luke Smith en la serie.
Alexander Armstrong interpreta a Mr Smith (voice) en la serie.
Daniel Anthony hace el papel de Clyde Langer.
Anjli Mohindra hace el papel de Rani Chandra.
Sinead Michael interpreta a Sky en la serie.
Capítulo disponible en las siguientes plataformas:
