- Kurt Kasznar - S.S. General Von Dreiberg
- Paul Shenar - Lieutenant Wertz
- Ed Begley Jr. - Harold Farnum
- Ike Eisenmann - Randy
- Bert Remsen - Dr. Jaffe
- Bob Seagren - Bryce Candle / Bret Cassiday
- Kerry Sherman - Kathy Munro
- Marisa Pavan - Maria
- Anne Ramsey - Connie
- Christopher Stone - Ryan
- Melanie Chartoff - Nadia
- Hayden Rorke - Professor Otis Warren
- Roman Gabriel - Roman Gabriel
- George Chakiris - Carlo Indrezzano
- Bradford Dillman - Arthur Deal III
- Bobby Van - Monty Burns
- Dick O'Neill - Pat O'Hanlon
- Jayne Kennedy - Carolyn Hamilton
- Peter Mark Richman - Dr. Crippin
- Marc Lawrence - Mr. Jones
- Sarah Purcell - Barbi Gordon
- James Sloyan - Mark Reuben
- John Zenda - Soldier
- Robert Shields - Doug
- Peter Marc Jacobson - Brad
- Jeffrey Byron - Henry Wilson
- Mitch Vogel - Mitch
- Lance LeGault - Otis Fiskle
- Philip Ahn - Colonel Minh
- David R. Ellis - Ludwig
- Penelope Windust - Dr. Sylvia Stubbs
- Hermione Baddeley - Mary Jane Thrip
- Denny Miller - Carl Schwartz
- Barry Dennen - Hitler
- David Hedison - Evan Robley
- Harry Guardino - Simon Penrose
- David Clarke - Sheriff Bodie
- James Hong - Oshima
- John Fujioka - Yamura
- Michael Cole - Ted
- Ross Martin - Bernard Havitol
- Barry Miller - Barney
- Frank Gorshin - Orlich Hoffman
- James Luisi - George
- Victor Argo - Jason
- Argentina Brunetti - Manageress
- Charles Cioffi - Raymond Manta
- Pamela Susan Shoop - Magda
- Murray MacLeod - Doctor
- Marc Alaimo - Pierce
- Scott Hylands - Paul Bjornsen
- Clark Brandon - Skip
- Earl Boen - Chaka
- Julie Anne Haddock - Tina
- John Aprea - Dupris
- John Hillerman - Conrad Steigler
- Lew Ayres - Dr. Kenneth Wilson
- Sheryl Lee Ralph - Bobbie
- Raymond St. Jacques - William Mayfield
- Dick Van Patten - Jack Wood
- Bubba Smith - Rojak
- Gary Burghoff - Alan
- Ross Elliott - Dr. Lazaar
- Charles Pierce - Starker / Finley
- Ed Gilbert - Warden
- Barbara Anderson - Maggie Robbins
- Brenda Benet - Morgana
- John Carradine - Harlow Gault
- Christopher George - Rojak
- Robert Reed - The Falcon
- Robert Alda - Harcourt
- Jeanne Bates - Mrs. Walls
- Carmen Filpi - Guard
- Russ Marin - Kleist
- Juliet Mills - Queen Kathryn
- Lucille Benson - Flo
- Leif Garrett - Lane / Michael
- John Reilly - Skye
- Michael Stroka - Henry
- Donnelly Rhodes - Ward Selkirk
- Roger Perry - Dunfield
- Kent Smith - Chief Justice Brown
- Irene Tsu - Mei Ling
- Alan Fudge - Major Cornell
- Rick Jason - Lawson Koslo
- Gil Stratton - Broadcaster
- Mel Ferrer - Fritz Gerlich
- Frank Parker - Lane Curran
- Joan Van Ark - Cassandra Loren
- Ellen Weston - Angelique
- Mako - Mr. Brown
- Eve Plumb - Elena
- Pamela Mason - Carla Burgess
- Charles Macaulay - Ambassador McCauley
- Kenneth Tigar - John Austin
- Buck Young - Foreman
- Bob Hastings - George
- John Milford - Mr. Keller
- Rick Springfield - Anton
- Jared Martin - David Gurney / Leon Gurney
- Dack Rambo - Andros
- Ted Shackelford - Adam Clement
- Vic Perrin - Gorel
- Anne-Marie Martin - June
- John Getz - Christian Harrison
- Joseph Maher - Edgar Percy
- Greg Morris - Caribe
- Arthur Malet - Professor Zander
- Keene Curtis - Mueller
- Carolyn Jones - Queen Hippolyta
- John Rubinstein - Major Dexter
- Jeremy Slate - Marshall Henshaw
- John Brandon - Sergeant Stransky
- David White - The General
- Gretchen Corbett - Erica Belgard
- John Colicos - Ambassador Orrick
- John van Dreelen - Dante
- Don Mitchell - Dr. Samson
- Wolfman Jack - Infra Red
- Allan Miller - Reynolds
- Ari Sorko-Ram - Emil Berger
- Milton Selzer - Captain Louie
- Charles Cyphers - Kurt
- Roger Davis - Jack Corbin
- Jennifer Darling - Violet Louise Tree
- Dick Butkus - Neil
- Nehemiah Persoff - Professor Moreno
- Bettye Ackerman - Asclepia
- Deacon Jones - Deacon Jones
- Art Metrano - Friedman
- Yuki Shimoda - Takeo Ishida
- Roy Rogers - J.P. Hadley
- James Staley - Guard #1
- Judge Reinhold - Jeff Gordon
- Brian Tochi - Darrell
- René Auberjonois - Kimball
- Michael Lerner - Ashton Ripley
- Joe E. Tata - Joe
- J.A. Preston - Jazreel
- Tad Horino - Yamura, Sr.
- Warren Stevens - Beal
- John Howard - Dr. Diderich
- Philip Michael Thomas - Furst
- Kurt Kreuger - Koenig
- Beatrice Straight - Hippolyta
- Joseph Sirola - Harrison Fynch
- Herman Poppe - Bodyguard
- Eric Braeden - Donalsen
- Eric Braeden - Captain Drangel
- Roddy McDowall - Henry Roberts
- Cletus Young - Official
- Vincent Van Patten - Johnny
- Jamie Tirelli - Gino
- Hanna Landy - Ms. Kell
- Allan Arbus - Bleaker
- Lynda Day George - Fausta Grables
- Steve Eastin - Johnny
- Fuddle Bagley - Shadow
- Peter Brandon - Dr. Norris
- Ron Ely - Bill Michaels
- Paul Sand - Del Franklin
- Fredd Wayne - J.J. MacConnell
- Kristoff St. John - Linc
- Joel Fabiani - Nightingale
- Nicolas Coster - Silas Lockhart
- Andrew Duggan - Mason Steele
- Martin Mull - Hamlin Rule
- Katherine Woodville - Adele Kobler
- Christopher Norris - Gloria Beverly
- Judyann Elder - Marge
- Anne Francis - Lola Flynn
- K.C. Martel - Ted
- Vaughn Armstrong - Eric
- Tim O'Connor - Colonel Robert Elliot
- Cathie Shirriff - Tara Landon
- Joe Warfield - IADC Officer
- Dean Harens - Dan Fletcher
- Henry Gibson - Mariposa
- Henry Gibson - Nikolas
- Gavin MacLeod - Mr. Ellsworth
- Leon Charles - Dr. Heinrich Von Klemper
- James A. Watson, Jr - Dr. Prescott
- Sam Edwards - Ernie
- George Cheung - Mr. Munn
- Hari Rhodes - Sheldon Como
- Charles Haid - Bob Baker
- Robert Loggia - Hans Eichler
- Ron Masak - Duane
- Sherry E. DeBoer - Admissions Clerk
- Lenora May - Melanie
- Arthur Batanides - Maxwell
- Allan Kolman - Dr. Rand
- Fil Formicola - Heavy
- James Bond III - T. Burton Phipps III
- Martin Speer - Billy Dero
- Ina Balin - Dr. Koren
- Herb Voland - Dr. Osmond
- Julio Medina - Captain Gaitan
- Joseph Chapman - Radioman
- Frank Marth - Tall Man
- Craig Littler - Thorpe
- Wayne Grace - Captain
- Robert Hays - Cpl. Jim Ames
- Celeste Holm - Dolly Tucker
- Harvey Jason - Professor Brubaker
- Patrick Cranshaw - Codger
- Regis Cordic - Professor Eidleman
- Russell Johnson - Colonel
- Christine Belford - Baroness Paula Von Gunther
- Lance Kerwin - Jeff Hadley
- Gary Crosby - Grease
- Mark Withers - Luther
- Steven Anderson - Sylvester Grogan
- Jason Johnson - James Porter
- Debra Winger - Drusilla / Wonder Girl
- Richard Narita - Lin Wan
- Sam Freed - Runner
- Britt Leach - Billy
- Kaz Garas - Lucas
- Fritz Weaver - Dr. Solano
- Suzanne Crough - Girl #2
- Armando Silvestre - Antonio Cruz
- Cindy Eilbacher - Jamie
- Charles Frank - Peter Knight
- Henry Darrow - David Allen
- Lee Bergere - Marius
- Bob Minor - Nick
- Michael Delano - Nick Moreno
- Gary Epper - Courier
- John Devlin - Major Keller
- Albert Paulsen - Crichton
- Tom Reese - Carl
- Burr DeBenning - Tom Baker
- Simon Scott - Sam Tucker
- Barry Van Dyke - Freddy
- E.J. Peaker - Lois
- James Olson - Wotan
- Larry Ward - Adler
- Jessica Walter - Gloria
- Albert Popwell - Gaffer
- Charlie Brill - Mr. Smith
- Doris Dowling - Mrs. Wilson
- Taaffe O'Connell - Val
- Milt Kogan - Kalanin
- Carmen Zapata - The Prime Minister
- Macon McCalman - Goodspeed
- Marvin Miller - Beamer
- Marlyn Mason - Lucy DeWitt
- Maurice Marsac - Maitre D'
- Christian Juttner - Tommy
- Frank McRae - Foreman
- Anthony George - Emmett Dawson
- Carlos Romero - Colonel Acevo
- Curt Lowens - Nordling
- Kurt Grayson - Harris
- Joseph R. Sicari - Leech
- Newell Alexander - Destroyer Commander
- Harris Yulin - Mark Bremer
- Craig T. Nelson - Sam
- Del Monroe - Thug
- Paul Tuerpe - CPO
- John Saxon - Captain Radl
- Stack Pierce - Desk Sergeant
- Scott Marlowe - Angie
- Danny Dayton - Louis the Lithuanian
- Mark Wilson - Magician #1
- Ernesto Macias - Senator Wainright
- Richard O'Brien - Frank Wilson
- Derna Wylde - Rosalie
- John Randolph - General Phil Blankenship
- Michael Shannon - Cameron
- Red Buttons - Ashley Norman
- Brian Davies - Thackery
- Brian Davies - Joseph Reichman
- Stella Stevens - Marcia
- Kenneth Mars - Colonel Von Blasko
- Cloris Leachman - Queen Hippolyta
- Arch Johnson - General Zachary Kane
- Arch Johnson - John Kelly
- Fannie Flagg - Amazon Doctor
- Scott Mulhern - Desk Clerk
- Mary Rings - Peasant Girl
- Millie Slavin - B. W.
- Inga Nielsen - Rena
- Ed Griffith - Hanson
- Colby Chester - S.S. Officer Horst
- Jeff Cooper - Major Charlie Scott
- Bill Fletcher - Nazi
- William Lanteau - Colonel Flint
- Erica Hagen - Dalma
- Jay Fenichel - Tommy
- Brad Rearden - Joey
- Albert Stratton - Charles Benson
- Michael Twaine - Frank Willis
- Mikki Jamison - Camilla Moret
- David Cryer - Hank Miller
- Don Eitner - Dentist
- Pat Skelton - Gormsby
- Janet MacLachlan - Sakri
- Hank Brandt - Graebner
- Christiane Schmidtmer - Lisa Engel
- George A. Cooper - Gen. Clewes
- Peter MacLean - Schmidt
- Maria Grimm - Lydia Moreno
- Alan Bergmann - Director
- Ross Bickell - Lt. Bill Rand
- David Himes - Sgt. Harry Willard
- David Knapp - Major Gaines
- Dorrie Thomson - Evadne
- Johana De Winter - Dr. Ross
- Tom Ormeny - Rogel
- Alan McRae - Security Officer
- J. Kenneth Campbell - Taft
- Christopher Cary - Mallory
- Christopher Cary - Beamer
- Alex Colon - Angel Velasquez
- Abraham Alvarez - Radio Car Officer Fernandez
- Brian Avery - Denny Lake
- Thomas Babson - Smitty
- Bo Brundin - Colonel Kesselman
- Bo Brundin - Vladimir Zukov
- Norman Burton - Joe Atkinson
- Ray Young - Tobirov
- Barry Cahill - General Miller
- Linda Ryan - Ruth Blaine
- Barbara O. Jones - Sell
- Donald Bishop - Dr. Royce Tobias
- Titos Vandis - Sutton
- Roger Callard - Bill
- Richard Gautier - Cagliostro
- Allen Williams - Hutchins
- Aharon Ipalé - The Emir
- Carol Worthington - Major Finley
- Lee Paul - Dirk
- Corinne Camacho - Capt. Anne Colby
- Kres Mersky - Theodora
- Todd Lookinland - Matthew Koslo
- Jane Actman - Meg
- S. Pearl Sharp - Eve
- Pamela Toll - Nurse
- Chuck Hicks - Thomson
- Michael Baseleon - Morley
- Robert Sampson - Bo Taggart
- Robert Sampson - Dr. Akers
- Robert Patten - Benjamin Springfield
- Victor Mohica - Lance
- Lorene Yarnell Jansson - Formicida / Dr. Irene Janis
- John O'Connell - Todd Daniels
- Diane Lander - Nancy
- Al White - Sergeant Cline
- Fred Lerner - Davis
- Fred Lerner - Kirk
- Steve Allie Collura - Bonelli
- Robert F. Hoy - Marty
- Robert F. Hoy - Norman
- John Durren - Alfie
- John Durren - Dale Hawthorn
- Sherrie Wills - Lisa
- Floyd Levine - Stryker
- James Lemp - George P. Turk
- Candy Ann Brown - Janet
- Paul L. Smith - Simon Rohan
- Carol Vogel - Dede
- Gwenn Mitchell - Guide
- David Yanez - Charlie Bright Eagle
- Lindsay Bloom - Tina
- Dawn Lyn - Whitney
- Michael McGuire - Moreaux
- Joe Maross - Shubert
- William Moulton Marston
- Douglas S. Cramer
Ricardo Montalban hace el papel de Abner Smith.
Victor Argo interpreta a Jason en la serie.
Judge Reinhold interpreta a Jeff Gordon en la serie.
Frank Gorshin interpreta a Orlich Hoffman en la serie.
Leif Garrett interpreta a Lane / Michael en la serie.
Marc Lawrence interpreta a Mr. Jones en la serie.
Nehemiah Persoff hace el papel de Professor Moreno.
Robert Loggia interpreta a Hans Eichler en la serie.
Paul Shenar interpreta a Lieutenant Wertz en la serie.
Harris Yulin interpreta a Mark Bremer en la serie.
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