- Peter Gallagher - Mitch Clarke
- Adam Beauchesne - MRI Tech
- Connie Chen - Ogling Woman #1
- Malinda Farrington - Lonely Woman
- Dan Sachoff - Lost Man
- Cindera Che - Old Woman
- Nick Baga - Bird Scooter Rider
- Damian Gomez - Miserable Man
- Mandy Moore - Mandy Moore
- Paul Feig - Dale Copperwood
- Sandra Mae Frank - Abigail
- Renée Elise Goldsberry - Ava Price
- Rebecca Wisocky - Nancy Wellington
- Zak Orth - Howie
- John Ralston - Paul
- India de Beaufort - Jessica
- Dohn Norwood - Pastor Steve
- Naoko Mori - Bonnie
- Justin Kirk - Charlie
- Ellie Harvie - Susan
- Bruce Dawson - Rick
- Stephanie Styles - Autumn
- Hiro Kanagawa - Dr. Hamara
- Chip Zien - Alan Richman
- Shadi Janho - Millennial
- Amanda Lisman - Gina
- Harvey Guillén - George
- Hunter Golden - Grumpy Guy
- Patti Kim - Judge
- Brandon Nomura - Client
- Robbie Segulam - Frank
- Elizabeth Weinstein - Middle-Aged Woman
- Arkie Kandola - Dentist Sanjay
- Jee Young Han - Jenna Kang
- Rob Stewart - Roger
- Jarrett Carlington - Jarrett
- Cecilly Day - Alicia
- Cecilly Day - Receptionist
- Kane Nelson - Kane
- Isaac Keoughan - White Employee #1
- Rachel Schaefer - White Employee #2
- Hannah Levien - Amanda
- Katie Findlay - Rosanna 'Rose' Williams
- Jacky Lai - Kaia
- Jaylee Hamidi - Hipster #1
- Scarlett Jando - Little Zoey
- Robert Kaiser - Ivana Prenup
- Jeremy Lacombe - Maximo Bartender #1
- Jacob Machin - Hipster #2
- Felix Mallard - Aiden
- Alvina August - Tatiana Morris
- Andres Joseph - Karan
- Levi Wall - Brock
- Ashlie Atkinson - Nova
- Thomas McDonell - Barnaby Steele
- Rohain Arora - Club Guy
- Donny Lucas - Pastor
- Gail Simpson - Dealer
- Bobby Stewart - Businessman
- Bernadette Peters - Deb
- Bryan Terrell Clark - Brad
- Noah Galvin - Patient in Waiting Room
- Becca Tobin - Patient in Waiting Room
- Bruce Blain - Croupier Fred
- Óscar Núñez - Dr. Tesoro
- Sara Alicia Garcia - Kersten
- Kayla Wallace - Amber
- Denzel Brooks - Curtis
- Michelle Choi-Lee - Doctor
- Michael Delleva - Zhang
- Ryan Irving - Josh
- Raj Lal - Raj
- Harry Singh - Vikram
- Noah Weisberg - Danny Michael Davis
- Morgan Taylor Campbell - Mackenzie
- Beta Chan - Cass
- David St. Louis - Perry Haskins
- Ildiko Susany - Ildiko
- Madeleine Kelders - Caregiver Applicant
- Emily Fox
- David Blackman
- Alex Newman
- Robert Sudduth
- John Terlesky
- Michele Greco
- Craig Wedren
- Jen Ross
- Bo Boddie
- Mateo Messina
Jane Levy interpreta a Zoey Clarke en la serie.
Skylar Astin interpreta a Max Richman en la serie.
Alex Newell interpreta a Mo en la serie.
John Clarence Stewart interpreta a Simon Haynes en la serie.
Andrew Leeds hace el papel de David Clarke.
Alice Lee interpreta a Emily Kang en la serie.
Kapil Talwalkar interpreta a Tobin Batra en la serie.
Mary Steenburgen interpreta a Maggie Clarke en la serie.
Capítulo disponible en las siguientes plataformas:
