- Sam McMurray - Lt. Griswald (voice)
- Sam McMurray - Bob Spinelli (voice)
- Mayim Bialik - Kristen Kurst (voice)
- Katey Sagal - Flo Spinelli (voice)
- Paul Willson - Coach Kluge (voice)
- Camille Winbush - Ashley 'Ashley T' Tomossian (voice)
- Kath Soucie - Jeffery, Baby (voice)
- Elizabeth Daily - Cap'n Sticky (voice)
- Justin Shenkarow - Gelman (voice)
- Rob Paulsen - Mr. Yamashiro
- Blake McIver Ewing - Menlow (voice)
- Tress MacNeille - Ms. Lemon (voice)
- Ryan O'Donohue - Randall Weems / Digger Dave (voice)
- Ryan O'Donohue - Randall Weems (voice)
- April Winchell - Miss Muriel P Finster (voice)
- April Winchell - Miss Finster (voice)
- Allyce Beasley - Miss Alordayne Grotkey (voice)
- Dabney Coleman - Principal Peter Prickly (voice)
- Erik von Detten - Erwin Lawson (voice)
- Erik von Detten - King Bob's Guard (voice)
- Francesca Marie Smith - Ashley 'Ashley B' Boulet (voice)
- Francesca Marie Smith - Ashley 'Ashley B' Boulet / Upside-Down Girl / Swinger Girl (voice)
- Rachel Crane - Ashley 'Ashley Q' Quinlan (voice)
- Robert Goulet - Mikey Blumberg (singing voice)
- Glenne Headly - Miss Salimony (voice)
- John Astin - Supt. Skinner (voice)
- Lane Toran - King Bob (voice)
- Anndi McAfee - Ashley 'Ashley A' Armbruster (voice)
- Cathy Moriarty - Dr. Fitzenberg (voice)
- Brian Doyle-Murray - Larry Rogen / Tommy Tate
- Jeff Wright - Hank the Janitor (voice)
- Patrick Renna - Jordan / Jerome (voice)
- Howy Parkins
- Chuck Sheetz
- Susie Dietter
- Brenda Piluso
- Cary Okmin
- Ford Riley
- Nahnatchka Khan
- Paul Germain
- Julie Ann Sipos
- Scott Shelley
Brian Doyle-Murray hace el papel de Larry Rogen / Tommy Tate.
Andrew Lawrence interpreta a TJ Detweiler (voice) en la serie.
Rickey D'Shon Collins interpreta a Vince LaSalle (voice) en la serie.
Pamela Adlon interpreta a Ashley Spinelli (voice) en la serie.
Ashley Johnson interpreta a Gretchen Grundler (voice) en la serie.
Jason Davis interpreta a Mikey Blumberg (voice) en la serie.
Courtland Mead interpreta a Gus Griswald (voice) en la serie.
Capítulo disponible en las siguientes plataformas:
