- BJ Harrison - Denise
- Théodore Pellerin - Wayne
- Aimee Carrero - Danielle
- Matthew Mandzij - Jeffries
- Charmaine Wilson - Adina
- Leo Chiang - Bob
- Spencer Drever - Jed
- Donald Sales - Bingham
- Jason Tremblay - Lance
- Colby Wilson - McClintock
- Robbie Segulam - Silver
- Angela Moore - Jennings
- Carmela Sison - Jackie
- Nitin Prasad - Kent
- Jessica Steen - Doreen
- Alessandro Juliani - John Marshall
- Roman Podhora - Larry
- Jed Rees - Gary Wippler
- Ashleigh Kearns - Jasmine Lippe
- Philip Granger - Howie Poascencia
- Alison Araya - Kiara Hudis
- Marc-Anthony Massiah - Fey Pascual
- Kayt Roth - Chantal
- Bill Pozzobon - Tim
- Jennifer Kitchen - Pubes
- Lia Frankland - Ella
- Kurtis Szarka - Jackson
- Chris Shields - James Campbell
- Jade Pawluk - Earl
- Russell Lee - Samson
- Bailey Skodje - Abigail
- Beckham Skodje - Addison
- Tim Perez - Luis
- Nick Preston - Kyle Decker
- Jill Morrison - Kelly
- Guy Christie - Eli
- Mila Jones - Young Alex
- Jeanie Cloutier - Sue
- Eileen Pedde - Dr. Baig
- Laara Sadiq - Helen Shaver
- Megan Leitch - Sasha
- Amy Reid - Jody
- Jessie Liang - Frankie
- Olivia Lucas - Rayna
- Terry O'Sullivan - Joyce
- Francisco Cano - Malik
- Kristina Capati - Mother
- Amy McInnes - Nanny
- Jane Stanton - Janice
- Toby Levins - Basil Desmond
- Requell Jodeah - Mina
- Sachin Sahel - Singh
- Daniel Bacon - Kurtis
- Tom Tasse - Gerald
- Paul C. Grenier - Jordan
- Madeleine Kelders - Shauna
- Miguel Castillo - Dale
- Raymond Ablack - Nate
- Christie Burke - Tania
- Gillian Barber - Melody
- Brenda Crichlow - Renee
- Sook Hexamer - Mrs. Kim
- Moon Hee Suk - Phyllis
- Scott Bellis - Dr. Till
- Patti Kim - Magda
- Shaker Paleja - Dr. Lim
- Erin Aubrey - Roberta
- Gloria Garayua - Penny
- Mercedes De La Cruz - Stella
- Mike Wasko - Tom
- Janet Glassford - Rita
- Morgana Wyllie - Nora
- Beau de Zwager - Stu
- Nels Lennarson - Brett
- Xavier de Guzman - Ethan
- Erin Karpluk - Sharlene
- Mozhan Marnò - Tara
- Steve Bacic - Micah
- Murry Peeters - Kyla
- Nancy Sivak - Esther
- Nhi Do - Trina
- Josh Chambers - Jake
- Stephanie Land
- Brett Hedblom
- Colin McKenna
- Margot Robbie
- Bonnie Benwick
- Tom Ackerley
- Molly Smith Metzler
- Este Haim
- Stuart Martin
- Christopher Stracey
- P. Patrick Hogan
- Joe DeAngelis
- Chris Carpenter
Margaret Qualley interpreta a Alex en la serie.
Nick Robinson interpreta a Sean en la serie.
Anika Noni Rose interpreta a Regina en la serie.
Andie MacDowell interpreta a Paula en la serie.
Tracy Vilar interpreta a Yolanda en la serie.
Billy Burke hace el papel de Hank.
Rylea Nevaeh Whittet interpreta a Maddy en la serie.
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