- Magda Apanowicz - Suzie Travis
- Fred Keating - Charles Henderson
- Anna Galvin - Lisa Stone
- Eve Harlow - Leila
- Paul Perri - Dr. Smithson
- Adrian Holmes - Sam Barton
- Emily Holmes - Joanne Scott
- Juan Carlos Velis - Roach
- Ted Whittall - President William J. Scott
- Ted Atherton - Edward 'Ed' Dewitt
- Roman Podhora - General Blair
- Jonathan Potts - Pat Terrence
- Denise Galik - Annie Dillon
- Kurt Max Runte - Sherriff Martin Willis
- Cory Dagg - General Michaelson
- Nicola Anderson - Lt. Amy Deacon
- Douglas O'Keeffe - Blonde Man
- Tom McBeath - Kyle Tobler
- Jesse Moss - Jeff Megan
- Kurt Evans - Lt. Roger Shawn
- Panou - Lt. Lewis Crane
- Candus Churchill - Sophie Derabond
- Graeme Duffy - Wheezer
- Daniel Bacon - Spokesperson
- Stacee Copeland - Henderson's Secretary
- David Ross - Hank Benedict
- Tom Butler - Colonel Scott Arnold
- Nels Lennarson - George the Guard
- Chris Bradford - Wildfire Comms
- Biski Gugushe - Sgt. George
- Matthew Smalley - Private Brooks
- Teach Grant - Morgue Attendant
- Bart Anderson - Al Ritter
- Donna Soares - Korean Nurse
- Luke Camilleri - Gordo
- Michael Teigen - Ocean Savior
- Jacob Blair - Operative #1
- Eric Breker - Operative #2
- Calvin Lee - Korean Major
- Michal Suchánek - Lance Stone
- Crystal Braunwarth
- Ken Shane
- Michael Crichton
- Robert Schenkkan
- Ron Binkowski
- David W. Zucker
- Ridley Scott
- Tony Scott
- Denise Chamian
- Tom Thayer
- Joel J. Richard
- Keith Rogers
- G. Michael Graham
- Richard Steele
Benjamin Bratt interpreta a Dr. Jeremy Stone en la serie.
Christa Miller interpreta a Dr. Angela Noyce en la serie.
Eric McCormack interpreta a Jack Nash en la serie.
Daniel Dae Kim interpreta a Dr. Tsi Chou en la serie.
Viola Davis interpreta a Dr. Charlene Barton en la serie.
Louis Ferreira interpreta a Colonel Ferrus en la serie.
Barry Flatman interpreta a Charles 'Chuck' Beeter en la serie.
Ricky Schroder interpreta a Major Bill Keane en la serie.
Andre Braugher interpreta a General George Mancheck en la serie.
Magda Apanowicz interpreta a Suzie Travis en la serie.
Capítulo disponible en las siguientes plataformas:
