- George Savalas - Curly Stavors
- George Savalas - Sgt. Stavros
- George Savalas - Det. Stavros
- George Savalas - Det. Stravros
- Kene Holliday - Assistant D.A. Dunn
- Kitty Winn - Carla Magid
- Maria Schell - Sister Lepar Angelica / Princess Viva Dushan
- Priscilla Barnes - Sally Addison / Vicki Addison
- Diana Hyland - Cleo Donatello
- Larry Haines - Michaels
- Harvey Keitel - Jerry Talaba
- James Keach - Ted Strong
- Ben Masters - Oliver
- Leslie Nielsen - Michael Hagar
- Lisa Pelikan - Jennifer Campbell
- Meeno Peluce - Christopher
- Judith Lowry - Lily Weed
- Verna Bloom - Carrie Zachary
- Dimitra Arliss - Sherry Kaufman
- Paul Shenar - Arthur Harris
- Joseph Bova - Morrie Rogaz
- Bernie Kopell - Sam Bernard
- Eddie Barth - Joe Torrey
- Robert Earl Jones - Judge
- Robert Ito - Sammy Loo
- Ahna Capri - Carol
- Neville Brand - Sonny South
- Michael Witney - Billy Dunvalo
- John Randolph - Judge Philip Templeton Mackie, Sr.
- Kathleen Widdoes - Sonia
- Evan C. Kim - Chok Low
- Richard Gere - Geno Papas
- Richard Romanus - Det. Sam Calucci
- Eric Christmas - O'Malley
- Scatman Crothers - Gaylord Fuller
- Al Freeman Jr. - Donald Mosher
- Danny Aiello - Matty
- Ann Jillian - Joanna
- Cristina Raines - Janelle Rawlings
- Mary Louise Weller - Stacy
- Veronica Hamel - Elenora
- John Sylvester White - Chief Copeland
- David Selby - Sgt. Jimmy O'Connor
- Silvana Gallardo - Lisa Diaz
- Richard Bradford - Joe Milner
- Bill Duke - Sylk
- Larry Kert - Whitney Farrow
- Dominic Chianese - George Mallick
- Rosalind Cash - Mrs. Moore
- David Doyle - Sgt. Harry Sumar
- Brad Dexter - Arnie Naylor
- Liam Dunn - Faxy
- Karen Morley - Mrs. Webber
- Michael Cristofer - Michael Viggers Jr.
- Richard Lawson - 1st Suspect
- Val Avery - George Janis
- Michael Mann - Dave
- Lillian Lehman - Lisa Keller
- Lane Smith - Clyde Regan
- Mike Kellin - Frank Conforti
- Julie Gregg - Shelby Phillips
- Erik Estrada - Luis
- Doris Dowling - Rosemary
- Season Hubley - Sister Maria
- Kay Medford - Bernice M. Sandler
- Oskar Homolka - Father Dimitrius
- Joanna Miles - Miss Lorelei Mason
- Brian Murray - Caesar Ogilvy
- Roscoe Orman - Lieutenant Connors
- Ron Rifkin - Rick Levene
- Lee Wallace - Hobart
- Lyman Ward - Larry Jordan
- David Ladd - Everett Coughlin
- Henry Darrow - Kevin Le Jeune
- Tara Buckman - Toni
- Lee Montgomery - David Hecht
- Barry Miller - Billy Sherback
- Lenny Montana - McCoy
- Jed Allan - Eddie Ryan
- Lynne Marta - Peggy Farrell
- Kevin Michael Richardson - Jimmy Crown
- Charles Cioffi - Arnie Brace
- Charles Aidman - Tom DeHaven
- Alex Dreier - The Man
- Bernard Barrow - Paul Paulus
- Bruce Glover - Henry Slote
- Yuki Shimoda - Assassin
- Charles Brown - Dan Garrett
- Arte Johnson - Billy Butler
- Mark Stevens - Manny Steiner
- Burr DeBenning - Cass
- Frank Campanella - Sammy
- John P. Ryan - Peter Ibbotson
- Stacy Keach, Sr. - Mr. Sperry
- James Murtaugh - Sutter
- Martin Balsam - Ray Kaufman
- Tony Burton - Eddie Ellis
- Irene Tedrow - Mrs. Hale
- Walter Brooke - Judge Lavery
- Martine Bartlett - Margaret McCune
- David Ackroyd - Vincent Hackley
- Suzanne Charny - Nina Bruno
- Elaine Shore - Bernadette Fopler
- Patrick Adiarte - Leonard Wong
- Abe Vigoda - Kilty
- Elizabeth Allen - Louise Linden
- George D. Wallace - Washburn
- Brooke Adams - Julie Winston
- Roger Aaron Brown - Thompson
- Frank Aletter - Capt. Nolan
- Bill McCutcheon - Fred Starrett
- Lola Albright - Celia Lamb
- Nicholas Colasanto - Victor Marchette
- Luis Ávalos - Victor Morales
- Robert Mandan - Dr. Michael Clossen
- Irene Cara - Amy
- Christopher Murney - Flarrety
- Gregory Walcott - Malcolm Cane
- Michael Gregory - Edgar
- Rick Hurst - Crew Cut Hostage
- David Opatoshu - Dr. Anton Valentine
- Judith Chapman - Gretchen Hodges
- Gale Garnett - Elaine Kastos
- Danny Wells - Riggs
- Gene Dynarski - Lairdson
- Elaine Joyce - Jo Anne Yager
- Beverly Sanders - Stella the Bank Teller
- Argentina Brunetti - Christina
- Barbara Rhoades - Joanna Ferro
- Meg Wyllie - Sister Agnes
- Gail Strickland - Monica
- Joe Turkel - Swampgas
- Norman Alden - Foster
- Caroline McWilliams - Ellen Roberts
- Swoosie Kurtz - Julie Di Nata
- Michael Storm - Joseph Magid
- Raymond Serra - Al Gregorio
- Murray Hamilton - Harry Harmon
- Roger E. Mosley - Stutz
- Edward James Olmos - Paco
- William Katt - Carey Nysrom
- Marco St. John - Tony Papas
- Lincoln Kilpatrick - Todd Flynn
- Paul Benedict - Kauldor
- Antonio Fargas - Benny
- Michael Cavanaugh - Sonny Canavere
- Oscar Beregi Jr. - Fuchs
- Earl Boen - D.A. Hepburn
- Jess Walton - Cheryl Pope
- Harry Guardino - Det. Benny Fiore
- Tony Sirico - Greek God
- Adam Wade - Roland Weeks
- Sam Jaffe - Papa
- Ed Lauter - Floyd
- Michael Lerner - Dr. Samuel Fine
- Lorraine Gary - Ruth Gardner
- Howard Platt - Roy Benson
- Susan Tyrrell - Mary Torino
- Armand Assante - Tom Ryan
- Richard Sanders - Drunk
- Susan Blu - Lover Girl
- Woodrow Parfrey - George Devane
- Danny Goldman - Sutherland
- Geraldine Page - Edna Morrison
- Maud Adams - Elenor Martinson
- John Reilly - Whelan
- Pat Corley - Mr. Miller
- David Ogden Stiers - Bryan LeBlanc
- Jeff Conaway - Bert Gaines
- Hurd Hatfield - Don Luiz Cabrillo
- Michael Constantine - Don 'Cheech' Frank Scalesi
- Alan Fudge - Gus
- George Morfogen - Charley
- Harry Bellaver - Light Duty Officer
- Paul Anka - Buddy Maus
- Dick O'Neill - Augustine Pataki
- Alan Napier - Antonakis
- John Pleshette - Resident
- Norman Burton - 'Fish' Fisher
- Sylvester Stallone - Det. Rick Daly
- Arnold Soboloff - Robles
- Richard Jordan - Steve Macey
- Roy Jenson - Frank Kelton
- Gene Baylos - Tex Alston
- Roy Poole - Police Captain Joe Keene
- Robert Alda - Adrian Marshall
- Leon Russom - Gallen
- Ruth Gordon - Miss Eudora Temple
- Jack Betts - Paul Lawford
- James Sloyan - Jack Murzie
- Bruno Kirby - Keith Wicks
- Jeff Corey - Frank Raynor
- Art Metrano - Mike Tomaso
- Ellen Bry - Leslie Smith
- Kathleen Quinlan - Janet Conforti
- Priscilla Pointer - Regina
- Russ Marin - Dr. Sullivan
- Harry Goz - Vito Coletti
- George DiCenzo - Harry Ferguson
- Roxie Roker - Carol Lessonbee
- Keone Young - Oriental
- Eric Braeden - Kenneth Krug
- Bruce Kirby - Sgt. Al Vine
- Julius Harris - Joe Addison
- Thaao Penghlis - Yanni Psalidas
- Curt Conway - Father Duggan
- Robert Webber - David Lawrence
- Frances Foster - Pearl Johnson
- Thayer David - Tyrone
- Thayer David - Mr. B
- Cliff Osmond - Gino
- Ray Sharkey - Gallagher (uncredited)
- Richard Eastham - Jack Seymour
- Philip Bruns - Mr. Seymour
- Philip Bruns - George Lampert
- Mary Jo Catlett - Verna
- Don Knight - John Hagen
- Don Knight - Pourette
- John Hillerman - Mark Gallant
- Jack Colvin - Maurice Cherneff
- Jane Elliot - Carla Elliot
- Paula Kelly - Janet Carlisle
- Jayne Kennedy - Tour Guide
- Karen Lamm - Dede
- Granville Van Dusen - Fred Toomey
- Peter Brandon - Dr. Theodore Shane
- Mari Gorman - Molly Lawson
- Al Ruscio - Joe Travino
- Al Ruscio - Jonas Vukich
- Helen Page Camp - Mrs. Waring
- Helen Page Camp - Mrs. Chester
- Shelley Winters - Evelyn McNeil
- Antoinette Bower - Diane Marco
- John Ashton - Cullen
- Mark Russell - Percy Saperstein
- Mark Russell - Det. Saperstein
- Mark Russell - Saperstein
- Jackie Cooper - Frank Mulvaney
- Kathleen Freeman - Ma Wonderly
- Joshua Shelley - Bob Harris
- Joshua Shelley - Obitsky
- Arthur Space - Ezra Rawlings
- Vince Conti - Det. Rizzo
- Vince Conti - Rizzo
- Vince Conti - Sgt. Rizzo
- Vince Conti - Agajanian
- Vince Conti - Police Photographer
- Joanne Linville - Ellen Ryan
- John Karlen - Hicks
- John Karlen - Pinky
- Roz Kelly - Susan
- Roz Kelly - Millie
- Rosey Grier - Salathiel Harms
- Jay Novello - Patriarch
- Daniel J. Travanti - Lt. Charles 'Chuck' Danena
- Daniel J. Travanti - Captain Badaduchi
- Matthew Arkin - Tony Curtin
- Grayson Hall - Mrs. Cambell
- Stewart Moss - Deerfield
- Danny Thomas - Asst. Chief Howard Brokaw
- Joseph Mascolo - Det. Jeff Braddock
- Christopher Walken - Ben Wiley
- Alex Rocco - Tony Curcio
- Alex Rocco - Morton Tallman
- Stanley Kamel - Bert Marino
- Stanley Kamel - Clyde
- John Lehne - Tony Howard
- Mark Shera - Patrolman Ralph Warren
- Gordon Jump - Jonas
- Buddy Lester - Lenny Karp
- Jon Cedar - Crowell
- Phillip Pine - Jason Kreiger
- Haywood Nelson - Bobby Moore
- Ken Foree - T.J. Smith
- Harvey J. Goldenberg - Mr. Doyle
- David White - Ramsey Brewer
- Gerald Peters - Chauffeur
- Lara Parker - Maria
- Lara Parker - Jenny Villers
- Bob Minor - Blood
- Whit Bissell - Sentman
- Jean Willes - Savannah
- Vincent Gardenia - Det. Vince LaGuardia
- Stephen Macht - Max Fisk
- Stephen Macht - Joe Arrow
- James Griffith - Mr. Swift
- Clarence Felder - Medical Examiner
- Clarence Felder - Dr. Bagley
- Richard X. Slattery - Egan
- Lynn Redgrave - Claire
- Simon Oakland - Tom Donnelly
- Alfred Ryder - Emile
- Pepe Serna - Rudy Diaz
- Pepe Serna - Enorio Patias
- Macon McCalman - McKee
- Jack Ging - Leo Becker
- Jack Ging - Hackford
- Richmond Shepard - Grundy
- Andrea Marcovicci - Lisa Walden
- Andrea Marcovicci - Francesca Milano
- Holland Taylor - Elizabeth
- Charles Napier - Marty Vaughan
- Forrest Tucker - Det. Paul Zachary
- Richard Bakalyan - Proctor
- Archie Hahn - Hacket
- James A. Watson, Jr - Richie Linden
- David Proval - Calvelli
- Sharon Gless - Nancy Parks
- Salome Jens - Olga Nurell
- Jack Donner - Krakauer
- William Prince - Baker
- Shelby Leverington - Joan Jordan
- Rose Marie - Mrs. Tildon
- Max Showalter - Quinlan
- Carmen Argenziano - Davey
- Sam McMurray - Duke Peter Dushan
- Jeffrey Tambor - Medical Examiner
- Maria Tucci - The Psychiatrist
- Fred Sadoff - Van Heusen
- Sam Freed - Dr. Bernstein
- Lynnette Mettey - Sgt. Doris Holloway
- Lynnette Mettey - Joannie Garretty
- Albert Popwell - Danny Boy
- Ji-Tu Cumbuka - Slade
- Ji-Tu Cumbuka - John 'Blue' Andrews
- Bert Kramer - Det. Walton
- Jennifer Warren - Eloise Geach
- Jennifer Warren - Carol Austin
- Thalmus Rasulala - Chief of Detectives
- Eddie Fontaine - Alex Fairbanks
- Malachi Throne - Mr. Ballantine
- Malachi Throne - Solly DeChico
- Sully Boyar - Louie Rindone
- Stephen McHattie - Paul Nelson
- Stephen McHattie - Ray Blaine
- Mary Beth Hurt - Karen Foster
- Eli Wallach - Lee Curtin
- Susan Sullivan - Carol Krug
- Susan Sullivan - Kelly McCall
- Hector Elizondo - Detective Nick Ferro
- Hector Elizondo - Carl Dettrow
- Kathleen Miller - Fern
- Morgan Fairchild - Allison
- Carl M. Craig - Det. Ben Keller
- Stephen Pearlman - Det. Sam Nemo
- Michael Alldredge - Katkoff
- Cynthia Harris - Helen Fielding
- Richard Venture - Capt. Reardon
- Richard Venture - Robert Smith
- Fionnula Flanagan - Molly Braddock
- Victor Campos - Detective Gomez
- Victor Campos - Det. Gomez
- Jack Bannon - David Fox
- George Maharis - Ringer
- Carmen Zapata - Ellen Conforti
- Paul Benjamin - Willie Daniels
- Michael Delano - Valano
- Michael Delano - Solerno
- Eileen Brennan - Julie Loring
- Rudy Bond - Ben
- Rudy Bond - Janitor
- Conrad Janis - D. A. Lynn
- Carol Lynley - Polly Ames
- John Glover - Billy Jo
- Francine York - Linda
- Buck Young - Reporter
- William Cort - Mr. Proctor
- John Pickard - Tom Donnelly
- Burke Byrnes - Det. Olney
- Eddie Firestone - Bunky Ott
- John Larroquette - Sailor
- Linda Carlson - Ellen Sherback
- Len Lesser - Hinton
- Len Lesser - Mr. Morgan
- Raymond O'Keefe - Laggo
- Eugene Roche - Seymore Haywood
- Eugene Roche - Patrolman Lyle 'Sandy' Beach
- Paul Mantee - Hank Yankowski
- Tina Louise - Audrey Norris
- Gretchen Corbett - Jeri
- Gianni Russo - Russ Barton
- John Ritter - Kenny Soames
- Ted White - Solly
- Chuck McCann - Lloyd Tatum
- Nicholas Georgiade - Gino
- Rosalind Chao - Grace Chen
- Jaime Sánchez - Thomas Serio
- Jaime Sánchez - Paolo Olivarez
- William Hurt - Jake
- Matthew Cowles - Ryan
- Louis Zorich - Mike DeBrieno
- Todd Susman - John Campbell
- Peggy Feury - Dr. Irene Benton
- Brian Dennehy - Peter Connor
- Norman Lloyd - Harry Fein
- Russ Grieve - Proctor
- Michael Durrell - Kenny Murray
- Michael Durrell - Pete
- Sara Seegar - Mae Lester
- Virginia Christine - Mrs. Yankowski
- Teddy Wilson - Joe Penney
- Peter Hobbs - Cortazzo
- Peter Hobbs - Kyle Becker
- Steffen Zacharias - Strickland
- Lee Weaver - Ozzie Turnbull
- Allan Miller - Bayliss
- Harrison Page - Quade
- Harrison Page - Hawthorn Yantzee
- Quinn K. Redeker - Neff
- Quinn K. Redeker - Lou Carver
- Dorian Harewood - Jake Riley
- Larry Gelman - Dr. Marcus
- Larry Gelman - Ramos
- Robert Loggia - Cassidy York
- Dan Hedaya - Dan Hudson
- Zohra Lampert - Dr. Ellen Page
- Zohra Lampert - Marina Sheldon
- Tom McFadden - Hawker
- Yvonne Craig - Liz
- Marc Alaimo - Artie
- Marc Alaimo - Joe Greensteen
- Tracy Reed - Dorothy Cunningham
- Phil Leeds - Druggist
- Ivor Francis - J. Warren Hale
- Ivor Francis - Henry W. Keiler
- Stephen Elliott - Tyler Meadows
- Paul Picerni - Det. Albert Cohen
- Paul Picerni - Vic Whitley
- Andrew Parks - Danny Fisk
- Harris Yulin - Bert Podis
- Ruth McDevitt - Mrs. Farenkrug
- Charles Kimbrough - Assistant D.A. Greg Burton
- Charles Kimbrough - Rudy
- Ken Kercheval - Ray Fromm
- Ken Kercheval - Teddy Maclay
- Ken Kercheval - Professor Lacey
- Michael V. Gazzo - Joel Adrian
- James Luisi - Capt. Henry 'Hank' Rosseau
- James Luisi - Det. Geno Alessi
- Joan Van Ark - Det. Josephine Long
- Regina Baff - Sister Catherine
- William Windom - K.C. Milano
- Albert Hall - Det. Gregg
- Paul Lambert - Hugh Jellicoe
- Dan Seymour - Broen
- David Wilson - State Prosecutor Josh Candoo
- Charles Siebert - Bender
- Leonardo Cimino - Ruby Kabelsky
- Leonardo Cimino - Cordick
- Dabney Coleman - Alex Linden
- Isabel Sanford - Grace
- Tige Andrews - Joe Paxton
- Tige Andrews - Sergeant Geno Polucci
- Tige Andrews - Aaron Fisk
- Nora Marlowe - Jacobs
- Lenka Peterson - Dr. Kirk
- Lenka Peterson - Dr. Barbara Kirk
- Thom Christopher - Capt. Juan Vida
- F. Murray Abraham - Solly Nurse
- F. Murray Abraham - Eddie Gordon
- Jerry Orbach - Brubaker
- Robert Picardo - Thomas Rindone
- Deborah White - Jacky Pierce
- Nick Dimitri - Dagger's Associate (uncredited)
- Jocelyn Brando - Mrs. Newfield
- Larry Block - Gerry Erskine
- Raymond Vitte - Prisoner
- Herb Edelman - Jack Cohen
- Herb Edelman - Toza Stefanovic
- Jack Somack - Muttel
- Jack Somack - Charlie Gerson
- Jeffrey Jones - Attendant
- Garry Walberg - Goodman
- Peggy McCay - Mrs. Smith
- Richard Herd - Bob
- Michael Tolan - Dr. Peter Allender
- John C. Becher - Dr. Bernard
- Biff McGuire - Defense Attorney Kingsley
- Michael Margotta - Jack Donnelly
- Lester Rawlins - Assistant D.A. Angus Moore
- Elizabeth MacRae - Betsy Vellon
- Elizabeth MacRae - Robin Clossen
- John Aniston - Webster
- John Aniston - Dancik
- Diane Baker - Irene Van Patten
- Hank Garrett - Turetsky
- Louise Sorel - Vicky Brewer
- Louise Sorel - Janice Maclay
- Danielle Brisebois - Jamie Magid
- Rudy Challenger - Lionel Lessonbee
- Louise Shaffer - Francie Foster
- Peter Bergman - Bo Allen
- Martin Kove - Burl Slote
- Mark Gordon - Detective 'Chic' Chiccaloni
- Patricia Triana - Teresa
- Ann Coleman - Felicity
- Carolyn Martin - Bertha
- Victor Argo - Joseph Crespi
- Victor Argo - Dennison
- Mark Dawson - Mr. Dahl
- John Vari - Victor Bruno
- Al Bain - Concerned Citizen (uncredited)
- Allan Rich - Solly's Lawyer
- Allan Rich - Judge Walter Miller
- Howard Honig - Farmer
- Howard Honig - Ted Owens
- Bill Morey - Tom Nolan (uncredited)
- Roger Robinson - Gil Weaver
- Sheree North - Mrs. Giancana
- Connie Sawyer - Mary Benson
- Connie Sawyer - Landlady
- Val Bisoglio - Barney Bramley
- Anthony Charnota - Victor
- Anthony Charnota - Serafin
- Anthony Charnota - Matthews
- Carmine Caridi - Jake Grubert
- Carmine Caridi - Stan Sherback
- Martin Braddock - Moore
- John Quade - Colby
- David Garfield - Bernheim
- Raymond Singer - Dr. Moscowitz
- Raymond Singer - Medical Examiner
- Raymond Singer - Moscowitz
- Joseph V. Perry - Talbert
- Joseph V. Perry - Bancroft
- Joseph V. Perry - Burke
- Edith Diaz - Celia Ortez
- Norbert Schiller - Mr. Polichek
- Ron Faber - Priest
- David Margulies - Midge Piper
- Mark Tapscott - Packman
- Lew Palter - Mr. Green
- Misty Rowe - Nadine
- John Mahon - I. A. D. Man
- John Mahon - Lawton
- Andy Romano - Larry Arcadia
- Basil Hoffman - Charlie Winston
- Carole Cook - Marie Stella
- Kenneth McMillan - Lt. Decker
- Kenneth McMillan - Lt. George O'Mara
- Kenneth McMillan - Lt. Becker
- Larry J. Blake - Desk Lt.
- Nick Dennis - Constantine
- Nick Dennis - Charlie
- Nick Dennis - Uncle Constantino
- Nick Dennis - Charley
- Guy Way - Extra (uncredited)
- John Armond - Bartender
- William Martel - Sgt. Grady
- Jack Hogan - Tom Turner
- Paul Sorensen - Frank Hennessey
- Fred Kareman - Al
- Lou Cutell - Dave
- Chuck Hicks - Hood (uncredited)
- Sally Kirkland - Clara
- Sally Kirkland - Gloria
- Sally Kirkland - Shirley
- Arnold Williams - Mitch
- Jerry Leon - Jumbo
- Alfred Dennis - Carmone
- Joe Alfasa - Falcone
- John Goddard - Mesche
- Alma Beltran - Mrs. Contreras
- Maggie Malooly - Peggy
- Alan Dexter - Ken Dimin
- Jack Aaron - Charlie Nose
- Raymond Mayo - Freddie
- Josie Johnson - Leona Crown
- Jenifer Shaw - Eloise
- J.S. Johnson - Eric
- Jon Rashad Kamal - Hindu
- Delia Salvi - Mrs. Servadora
- Charles Wagenheim - Hepplewhite
- Larry Watson - Arkansas Fowler
- Larry Watson - Fowler
- Darrell Zwerling - Agajanian
- Darrell Zwerling - Dr. Agajanian
- Darrell Zwerling - Medical Examiner
- Robert Brubaker - Deputy Com. Cowan
- Gil Serna - Sandro
- Nicholas Cortland - Nicky Cole
- Melvin F. Allen - McGregor
- Jon Silo - Krouse
- Robert Nadder - Cutter
- Sandy Balson - Melanie Lawrence
- Nick Ferrari - Carl Allender
- Lou Fant - Olsen
- Nelson Olmsted - Manager
- Steve Cory - Parking Attendant
- Sid Grossfeld - Turner
- Michael Keep - Bunce
- W.T. Zacha - Weaver
- Penny Santon - Sophie
- Janice Heiden - Alexandra
- Robert Donley - Henshaw
- Lionel Johnston - Eugene
- Ray Ballard - Mort
- Edward Ansara - Father Aleksei
- James V. Christy - Jimmy
- Paul Henry Itkin - Asst. D.A. Waters
- Louie Elias - Art
- Paul Cavonis - Gabe
- Vince Martorano - Vince
- Michele Nichols - Barbara Underwood
- Jack Manning - Benoit
- Borah Silver - Prince
- Borah Silver - Dr. Prince
- Borah Silver - Sgt. Prince
- Borah Silver - Chemist
- John Gilgreen - Porter
- Reb Brown - Furniture Man
- Frenchia Guizon - Foreman
- Mariclare Costello - Diane Gordon
- Burton Armus - Burt Armus
- Burton Armus - Detective
- Burton Armus - Spotter
- James Woods - Caz
- Jack Murdock - Art
- Pamela Hensley - Delta
- Wayne Heffley - Det. Steiglitz
- Mwako Cumbuka - Jonas
- James Wheaton - Mr. Scott
- Eddie Lo Russo - Waiter
- John Francis - Bartender
- Colby Chester - Spencer Galen
- Robert Burr - Daniel Pope
- Candice Azzara - Milly Blasky
- Candice Azzara - Agnes
- Steve Gravers - Pullian
- Erica Yohn - Mrs. Donner
- Erica Yohn - Mrs. Warren
- Harry Hickox - Winkler
- Paula Victor - Mrs. Getz
- Jerome Guardino - Voice Print Man (uncredited)
- Jerome Guardino - Vince Karabian
- Jerome Guardino - Bartender
- Jerome Guardino - Karabian
- Lou Tiano - Pulaski
- Fred Franklyn - Berrigan
- Fred Franklyn - Nightclub Manager
- Paul Micale - Bartender
- Jack Griffin - House Detective
- Austin Stoker - Det. Douglas
- Jerry Summers - John David
- James Beach - Plainclothesman
- Lauren Gilbert - Gance
- Anne Newman Bacal - Deidre
- Robert Darnell - Dr. Grimaldi
- Michael Ansara - Keith McCallum
- Marjorie Bennett - Emily Pembroke
- Dick Peabody - Burgess
- Frederick Coffin - Lt. Lee
- Frederick Coffin - Lt. Bill Lee
- Charlie Picerni - Cabbie
- Charlie Picerni - Dennis
- Paul Michael Glaser - Lou Giordino
- Sian Barbara Allen - Lyndsey Walker
- Alexandra Hay - Elena Rozelle
- John Beal - McKinney
- Jason Wingreen - Max Persky
- Jason Wingreen - Reporter
- Jason Wingreen - Eddie Hogan
- Charles Dierkop - DeLuca
- Ed Bernard - Watson
- Joseph X. Flaherty - Jerome Smith
- Joseph X. Flaherty - Regan
- Fuddle Bagley - High Pockets
- Dennis Patrick - Clay Dexter
- Russell Wiggins - Marty
- Robert Doyle - Harry
- Ken Ruta - Bryce
- Laurence Haddon - Steadman
- Laurence Haddon - Capt. Ernie Perkins
- Michael Richardson - Jimmy Crown
- Lenny Kent - Mesche
- Catlin Adams - Sheila
- Catlin Adams - Adelle
- Catlin Adams - Theresa Ryan
- Steven Keats - Danny Zucco
- Rafael López - Bellboy
- Rafael López - Pena
- Joan Pringle - Neva
- Don Hanmer - Myron Joyce
- Don Hanmer - Darata
- Brit Lind - Alice Fisher
- Paul Jenkins - Timmy Oakes
- Joshua Bryant - Simon Hecht
- Dori Brenner - Miss Rosenberg
- William Tepper - Santangelo
- Linda Weeks - Paula McKeown
- Milton Selzer - Nathan Davidoff
- Joseph Hindy - Dominic Bruno
- Joseph Hindy - Vinnie Pomerantz
- Joseph Hindy - George Bradbury
- Jesse Dizon - Calvin Loo
- Shirlee Kong - Nancy Wong
- Judson Pratt - Danny Boyle
- Henry Brown - Omar "Miami" Blake
- Henry Brown - Forbes
- George Wyner - Asst. DA Linnick
- George Wyner - Sergeant Collins
- Ralph James - 'Fats' Giancana
- Ralph James - Louis 'Fats' Giancana
- Seamon Glass - Enforcer
- Seamon Glass - Terry the Enforcer
- Dick Balduzzi - Angie
- Dick Balduzzi - The Bartender
- Don Calfa - Fidelio Ortez
- Don Calfa - Burgess
- Brendan Burns - Tony
- Isa Crino - Nancy Sperry
- Kim Hamilton - Sgt. Donna Mill
- Robert Riesel - Reporter
- Robert Riesel - Colbenz
- Esther Sutherland - Evangeline
- Art Lund - Special Agent Ike Watkins
- Alex Colon - Raul Fria
- Don Fenwick - Malloy
- Don Fenwick - Roy Fine
- Miko Mayama - Mai Lee
- Louis Guss - Karl Scheer
- Louis Guss - Fred
- Alan Feinstein - Lenny Grenfell
- Zitto Kazann - Sheik Ali
- Harvey Fisher - Sergeant Way
- Richard Karlan - Henshaw
- Richard Karlan - Captain
- Richard Karlan - Uniformed Capt.
- Mike Robelo - Manny
- Mike Robelo - Williamson
- Melendy Britt - Joan Marly
- Mark Giardino - Medical Examiner
- Mark Giardino - Otto
- Mark Giardino - Hamerman
- Don Ross - Steven Marly
- Jack Stamberger - Ernest O'Reilly
- Frances Osborne - Secretary
- Joseph R. Sicari - Delman
- Joseph R. Sicari - Ferret Face
- Eugene Troobnick - Koster
- Frank Christi - Marty Clifford
- Don McGovern - Riessen
- Ian Scott - Jurgen
- Tom Pedi - Filacchione
- Margaret Avery - Lula
- Burt Berger - Wexler
- Melissa Murphy - Kimberley Hyatt
- Dorothy Tristan - Ellen
- Bruno VeSota - Revelson
- Jack Kutcher - Rizell
- Walter Stocker - Judge Mackie, Jr.
- Maria Elena Cordero - Marinella Olivarez
- Helena Carroll - Nun
- George Skaff - Delorme
- George Skaff - Mr. Zaloomian
- Tom Bower - Brenner
- Ronald G. Joseph - Latin
- Hank Rolike - Bootblack
- Gina Smika Hunter - Girl
- Susan Brown - Janet Seymour
- Bob Goldstein - Medical Examiner
- Buffy Dee - Catonsky
- Jon Jacobs - Sweetzer
- Vincent Baggetta - Nino La Rocca
- Vincent Baggetta - La Rocca
- Vincent Baggetta - Arnold B. Saxler
- Harold J. Stone - Franco 'Six Bits' Donatello
- Lenny Baker - Joyce
- Angela Clarke - Mrs. Harrington
- George Shannon - Greg
- Peter Carew - Mr. Dean
- Helen Verbit - Molly Kramer
- Linda Scruggs - Karen
- George Loros - Corso
- George Loros - Big Chrissy
- Diane Sherry Case - Bobby Jordon
- Carlo Manchini - Paul Valley
- Ja'net DuBois - Paula Thomas
- Ed Cambridge - Waverly
- Jac Emel - Jojo
- Nate Esformes - Leonard Tapler
- Anne Wyndham - Linda
- Robert De Anda - Mando
- Lorinne Vozoff - Dolores
- George Ball - Sam Corso
- Robert Modica - Handleman
- Dave Morick - Houghton
- Dave Morick - Asst. D.A. Casey
- Peter Mamakos - John
- Michael Ebert - Aldo Quire
- Robert Emhardt - Marcus
- Asher Brauner - Crater
- Asher Brauner - James Sperry
- Maria Grimm - Susan
- Mickey Fox - Katrina
- Evelyn Russell - Mrs. Desmond
- Evelyn Russell - Mrs. Tyburn
- Robert Viharo - Raymond Callis
- Randy Kirby - Carter
- Terence Locke - Farley
- Sam Laws - Eddie Maxwell
- Bonnie Bartlett - Joan Milner
- Ellen Madison - Marge Becker
- Michael Goodwin - Clements
- Carole Demas - Marie
- Sandra Deel - Mrs. Grubert
- Alan Manson - Lt. Steve Nicola
- Alan Manson - Gallagher
- Alan Manson - Inspector Nicola
- John Kerry - Mickey
- Jack Rader - Tony
- Mark Margolis - First Gunman
- Mark Margolis - Gunman
- Patrick Strong - Lester
- Martin Garner - Moishe
- Don Billett - Griss
- Don Billett - Graves
- Albert Henderson - Police Captain
- Albert Henderson - Denny Schwartz
- James Espinoza - Ramirez
- Michael C. Gwynne - Blaise
- John Dullaghan - Farrell
- Jean Le Bouvier - Lillian McNeil
- Richard Carlyle - Mr. Waring
- Arny Freeman - Sheldon
- Norman Matlock - Parsons
- Paul Sparer - Diamond
- Claude Earl Jones - Det. Al Buchinsky
- Scott Ben-Yashar - Wilson Stronik
- Chas. Floyd Johnson - Det. White
- Michael Mullins - Johnny
- Madison Arnold - Harry Dubin
- Madison Arnold - Joe Hennessey
- John Lisbon Wood - Don Collins
- Eunice Christopher - Mary Drosinis
- Tony Giorgio - Bill Wilson
- Gene Krischer - Addict
- Cynthia Avila - Lena
- Bill Lazarus - Pete
- Barbara London - Angie
- Anthony Pena - Chucho
- Victor Arnold - Malloy
- Albert Cole - Sutton
- Albert Cole - Berlin
- David Sabin - Crawford
- Jess Nadelman - Tobias Carson
- Royce Wallace - Liz Vernon
- Robert Carricart - Mr. Viliano
- Ben Hammer - Alex Ross
- Ben Hammer - Nick Vane
- Michael McGuire - Scroope
- Michael McGuire - Paul Merchison
- Robert Patten - Forman
- Frank Pesce - Jerry Gerson
- Frank Pesce - Spencer
- Burt Douglas - Draper
- Walter McGinn - Martin Bronson
- Walter McGinn - Len Gittings
- Robert Sutton - Manny 'No-Nose' Gagliano
- Robert Sutton - Patsy
- Robert Sutton - No-Nose Gagliano
- Joseph Stern - Nathan Markowitz
- Richard O'Brien - Sgt. Harry Doyle
- Wayne Grace - Grisco Cummings
- Edd Gasper - Vince Nesmith
- Tony Mumolo - Barry Schuster
- Titos Vandis - Michael Viggers Sr.
- Len Jewell - Tocco
- Lou Epton - Manager
- Dallas Mitchell - Attorney
- Wil Albert - Dr. Ennis
- Shimen Ruskin - Ben Hillel
- Tony Swartz - Milt Moyer
- Anna Berger - Mrs. Lipnick
- Andrew Robinson - Roger Layton
- Andrew Robinson - Leon
- Bob Bralver - Teddy
- Sally Kemp - Geraldine Marshall
- John Elerick - Penny
- John Elerick - Mike
- John Wyler - Fletcher
- Dolores Mann - Nancy Fletcher
- Barbara Douglas - Claudine
- Mary Margaret Amato - Jennie
- Sidney Clute - Barney Sullivan
- Sidney Clute - Det. Jackson Kilpatrick
- Sidney Clute - Det. Cahan
- Joey Aresco - Sammy
- Joey Aresco - Richie Centorini
- Karmin Murcelo - Mrs. Mendez
- Karmin Murcelo - Isabella
- Judy Kaye - Public Defender Penny Rozelle
- Allen Joseph - Mr. King
- Allen Joseph - Night Man
- William Wintersole - Chief Peck
- Richard Karron - Alley Oop
- Brett Hadley - Santa Flora
- Trish Hawkins - Olga
- Trish Hawkins - Fern
- Joe George - Sgt. Dobieski
- Joe George - Lewis
- Joe George - Frank
- Beverly Dixon - Victoria Goss
- Del Hinkley - Anslow
- Don Dolan - Baker
- Juno Dawson - Inez Wilder
- Juno Dawson - Hooker
- Walter Wonderman - Freddie The Fender
- Howard Brunner - Man
- Lonny Chapman - Lt. Follmer
- Jay Varela - Sam Lopez
- Dean Santoro - Walter
- David Hayward - Scott
- David Knapp - Thackery
- Mike Darnell - Nick
- Jesse Welles - Loretta Kane
- Betsy Slade - Alison DeWitt
- Darrell Fetty - Douglas North
- Redmond Gleeson - Det. Houston
- Fred D. Scott - Dr. Banker
- George Pan Andreas - Nico Trifores
- Rhoda Gemignani - Katrina Patropolous
- John Durren - Andy Rhodes
- John Durren - Benson
- Frank Geraci - Big Irv
- Richard Stanley - Arnold
- Kenneth O'Brien - Silas
- Kenneth O'Brien - Ankrum
- Giorgio Tozzi - Anselmo
- George Garro - D'Amato
- Charles Weldon - 'Shotgun Willie' Baine
- Dee Timberlake - Dellia May
- DeForest Covan - Cabbie
- Ned Glass - Deitz
- Harry Davis - Desk Clerk
- Teno Pollick - Niko
- Donna Mitchell - Lena Martin
- Julie Garfield - Paulina
- Daniel Faraldo - Nico
- Ron Max - Officer Mason
- Michael Vale - Nightclub Manager
- Joe Zaloom - Bartender
- Frances Helm - Travel Agent
- Howland Chamberlain - Park Attendant
- Themi Sapountzakis - Young Cop
- Sidney Armus - Arnie Geld
- William Griffis - Tatum
- Ed Crowley - Kelly
- James Dybas - Dr. Winkler
- Ken Sylk - Roger Villers
- Delos V. Smith Jr. - Semmelman
- Heath Jobes - Killer
- Jess Osuna - George Rhine
- Rudolph Willrich - Cafe Owner
- Ernesto Gonzalez - Diaz
- T.J. Castronovo - Frenchy Du Bois
- T.J. Castronovo - Mr. Burke
- T.J. Castronovo - Gene Vacelli
- Hortensia Colorado - Mother
- Joe Silver - Chief Wilson
- Carlos Augusto Cestero - George Sanchez
- Paula Trueman - Celia Moore
- Tito Goya - Chino
- Francisco Prado - Garcia
- Mary-Joan Negro - Janet O'Connor
- Lionel Pina - Hector Diaz
- James Sutorius - Benny
- James Sutorius - Lawson
- Teodorina Bello - Mrs. Diaz
- Martin Cassidy - Tom Carley
- Caesar Cordova - Superintendant
- Robert Stattel - Reporter
- Alba Oms - Puerto Rican Woman
- Chuck Bergansky - Brad Quinn
- Chuck Bergansky - Ed Teechan
- Chuck Bergansky - Dagger
- Ben Slack - Sonny Scammons
- Sam Locante - Joe Mallick
- Barney McFadden - Leo
- Jaime Montilla - Andy
- David Gale - IAD Man
- Jim Brochu - Tony
- Charles Guardino - Charlie
- Helen Craig - Mrs. Janowski
- Helen Craig - Mrs. Whipple
- Michael Lombard - Dr. Garvey
- Janet Ward - Miss Slovack
- Mark LaMura - Jed Cosgrove
- Joseph Leon - Willis Newton
- Bob Levine - Ward
- Ellen O'Mara - Sally Jo
- Cynthia Belgrave - Mrs. Murtle Carr
- Bill Moor - Mr. Cosgrove, Sr.
- Earl Rowe - Mr. Allen, Sr.
- Gus Fleming - Doctor
- Gordon Oas-Heim - Louis
- William Fort - Charlie
- William Fort - Charlie The News Vendor
- Elaine Aiken - Mrs. Foster
- George Lee Miles - Sgt. Resnik
- Leib Lensky - Charlie The Broom Man
- David Gideon - Chauffeur
- Vivian Nathan - Mrs. Coletti
- Gene Gross - The Hit Man
- Norman Parker - Father Moiso
- Ron Hunter - Marlow T. Caswick
- Jay Hargrove - Hearse Driver
- Alex Courtney - Det. Evans
- Alex Courtney - Frank DeMarco
- Miguel Piñero - Rudy
- Barry Snider - Tony Mira
- Dick Boccelli - Tommy
- Sammy Smith - Sammy
- Bradford English - Royce
- Bradford English - Cop at the Church
- Bradford English - Patrolman Seymour
- Richard Kuss - Heavy Set Hood
- Tuck Milligan - Hotel Clerk
- Joe Lo Grippo - Whelan's Driver
- Fred Morsell - Medical Examiner
- Lou Quinones - Cuban Hit Man
- Richard Foronjy - Ferarro
- Richard Foronjy - Davis
- Pi Douglass - Cabbie
- Richard Reicheg - Richard
- Richard Reicheg - Wickes
- Blair Brown - Stella
- Maureen Anderman - Assistant D.A. Lockman
- Charles White - Reilly
- Martin Rudy - Albert Beck
- Lee Bryant - Rita McCall
- Lee Bryant - Cindy
- Patricia Mauceri - Yolanda
- Milt Kogan - Dr. Martin Laing
- Milt Kogan - Al Grant
- Fat Thomas - Schuyler
- Antony Ponzini - Duff
- Antony Ponzini - Fiorello
- Noberto Kerner - Anton Lenco
- Noberto Kerner - Paco Rodriguez
- Hazen Gifford - Norton
- Maria Antoinette Rogers - Mrs. Arrow
- John Hallow - Al Danton
- Charles Welch - Dugan
- Richard Cummings Jr. - Basketball Player
- Richard Cummings Jr. - Louis Daniels
- Phillip R. Allen - Lt. Williamson
- Phillip R. Allen - Andy Cooper
- Patricia Elliott - Christina
- David Harris - Bucky Norris
- David Vasquez - Carlos Rivera
- Gary Bolling - Stubby Belton
- Roger Serbagi - Lane
- Charles Randall - Mr. Van Ord
- Jo Davidson - Mr. Drebbin
- Sam Singleton - Willie
- W. Benson Terry - Albert Johnson
- Stephen Joyce - The Priest
- Jane Hoffman - Maggie
- Arthur French - Eddie
- James Bryson - Mr. Penney, the Jailer
- Dale Robinette - Barry
- Lorry Goldman - Mr. Taylor
- Eugene Elman - Mr. Garbers
- Alberto Vazquez - Carlos
- Tony Padrón - Luis
- Gonzalo Madurga - Father Rico
- Gloria Irizarry - Maria
- Barton Heyman - Alistar McKnee Jr.
- Lou Gilbert - Goldstein
- Gregory Rozakis - Frankie the Mouth
- Virginia Vestoff - Helen
- Timothy Meyers - Stosh
- Phil Rubenstein - Charlie
- Joe Sorbello - Hal
- Frank Bongiorno - Megan
- Frank Bongiorno - Joe Megan
- Liz Sheridan - Rose
- Floyd Levine - Thompson
- Floyd Levine - Nelson Hewett
- Scott Firestone - Andy Foster
- Armand Dahan - The Extremist
- Albert Paulsen - Shelley Briscoe
- Judith Light - Laetitia Pomerantz
- Jack Hollander - Dinky Geller
- Anita Dangler - Mrs. Nugent
- Sheila M. Coonan - Superintendant
- Vincent Van Lynn - Danziger
- Ryan Hilliard - Courtroom Guard
- Charles McCarthy - Gun Range Keeper
- Tom Quinn - Superintendent
- Jack Axelrod - Forensics Man
- Jake Dengel - Sammy The Wino
- Michael Granger - Mr. Burbridge
- Sam Schacht - Dr. Riddle
- Iraida Polanco - The Nurse
- Ted Beniades - Florentino
- Harold Gary - Walter Zeif
- Gloria Grahame - Helen
- John Kellogg - Marvin Rubicoff
- Graham Beckel - Lane
- Paul Rossilli - Julian
- Toni Kalem - Nora
- Jerry Jarrett - Gregory
- Michael Egan - Victor
- Leonard Jackson - Dr. Logan
- Elena Karam - Aunt Angeline
- Michael Hardstark - Lewis Ginzberg
- Fred Steinharter - Doorman
- Jack R. Marks - Police Patrolman
- Drew Snyder - Stuart Bayliss
- Kevin Maung - Shimizu
- Count Stovall - Bud Powers
- Bernie Passeltiner - Lou the Waiter
- John Perkins - Witness
- Edward Power - Federal Agent Robinson
- Cathey Paine - Linda
- Mike Lane - Curly
- Jan Peters - Ben
- Lynne Topping - Charlene
- Doug Hale - Bradford
- Jenny O'Hara - Ann Murray
- Jed Cooper - Simpson
- Howard Witt - Garage Manager
- Susan Adams - Sgt. Harriet Clark
- Craig Huxley - Howie Green
- Bill Vint - Diesel Ramero
- Lawrason Driscoll - Jess Hoffstetter
- Gene Davis - Expert
- John Sarno - Smoot
- Larry Ellis - Dentist
- Gary Swanson - Bobby
- Bernard Behrens - Marshall Tyler
- Aharon Ipalé - Andre
- Bill Capizzi - Forensics Man
- Bill Capizzi - Forensic Man
- Ward Wood - Bob Lawrence
- Leigh Hamilton - April Daily
- Fred Beir - Robbie Austin
- Kirk Calloway - Harold Woods
- Sam Gilman - Howard Blaine
- Sheila Wills - Leilah
- Edwin Mills - Dr. Wade Ellis
- Merrie Lynn Ross - Hooker
- David Clennon - George Martin
- Brian Farrell - Fred Toner
- Adrian Ricard - Mrs. Raines
- Angel Tompkins - Jocelyn Mayfair
- James Blendick - Phil Brean
- Erica Hagen - Donna Socrates
- Margaret Fairchild - Mrs. Mayfair
- Paul Larson - Larry Morton
- Shera Danese - Sally Centorini
- Stewart Steinberg - Joe Kane
- Herbie Braha - Greg Kirkorian
- Douglas Dirkson - Alvin Kettle
- Nick Pellegrino - Alonzo
- Sammy Williams - Billy Spender
- Ralph Byers - Chris Wyatt
- Ben Piazza - Irving Abernathy
- Maria Smith - Cecilia Quinones
- Laura Campbell - Edith Leverkune
- Marti Stevens - Beth Avild
- Fred Carney - Judge Walter Cleary
- Bob Basso - Louie
- Paul Napier - Joseph Yardley
- Ray Duke - Patrolman Logan
- Richard Roat - Defense Attorney
- William Larsen - Deputy Inspector
- Steve Franken - Arnie Goldman
- Benny Baker - Danny Fogarty
- Ric Mancini - Woody
- Jill Jaress - Harriett
- Jon M. Benson - Dr. Whelan
- Marc Hannibal - Andy Quinn
- Liberace - Liberace
- Sondra Blake - Marie
- Frank Sivero - Morgan
- Michael Baseleon - The Major
- Gail Landry - Irene DeMarco
- David Hollander - Robbie DeMarco
- Justin Lord - Patrolman Gardner
- John Nolan - Ingram
- Robert Ball - Willie
- Bob Maroff - Doorman
- Charlene Dallas - Monica Brady
- Gary Allen - Hector
- Donegan Smith - Dave Simmons
- Karen Montgomery - Patricia
- Dennis Burkley - Bartender (uncredited)
- Dick Cherney - Party Guest (uncredited)
- Matthew Rapf
- Abby Mann
- James Duff McAdams
- Jack Laird
Victor Argo interpreta a Joseph Crespi en la serie.
John Ashton hace el papel de Cullen.
Harvey Keitel interpreta a Jerry Talaba en la serie.
Stephen Elliott interpreta a Tyler Meadows en la serie.
James Griffith interpreta a Mr. Swift en la serie.
Abe Vigoda interpreta a Kilty en la serie.
Gianni Russo interpreta a Russ Barton en la serie.
George DiCenzo hace el papel de Harry Ferguson.
Rudy Bond hace el papel de Janitor.
Edward James Olmos interpreta a Paco en la serie.
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