- Tom Williamson - Prince Promomomo
- Ethan Wacker - Collin Cleveland
- Rick Fox - Richard Martin
- Adam Irigoyen - Tolentino
- Sully Zack - Lorenzo
- Dante Swain - Aaron
- Barrett Carnahan - Spencer
- Noah Crawford - Gabriel Andrews
- Nikki Castillo - Akina
- Lori Mae Hernandez - Lecia
- Ashley Fink - Reena
- Trevor Jackson - Lincoln
- Ashlee Füss - Juli
- Jack DePew - Ryan
- Rick Hall - Agent Johnson
- Terence J. Rotolo - Enemy Spy
- Mckenna Grace - Quinn
- Leah Bateman - Alina Grady
- Tony Cavalero - Wally
- Charles Robinson - Pops
- Diane Delano - Regina Honey
- Ciera Foster - Herself
- Erron Jay - Olu
- Jackée Harry - Betty
- Luana Pires - Wanda
- Jay Reeves - Jordan
- Amy Johnston - Target
- Seth Austin - Target
- David Shatraw - Mr. Forman
- Madison Horcher - Trudy
- Monica Young - Mrs. Johnson
- Bella Thorne - Jolie
- Kurt Scholler - Mr. Enright
- Anna Ross - Molly Lopez
- Timothy Eulich - Pirate #1
- Nicholas Verdi - Pirate #2
- Randall Archer - Pirate #3
- Ross Butler - Brett Willis
- François Chau - Zane Willis
- Rick Marcus - Agent
- Sherri Shepherd - Agent Beverly
- Paras Patel - Delivery Guy
- Daniel David Stewart - Stanley
- Jaime Moyer - Mrs. Goldfeder
- Fred Stoller - Herb
- Roz Ryan - Gayle King
- Roz Ryan - Grandma Gayle
- Tony O'Dell - Mr. Hancock
- J. Anthony McCarthy - Policeman
- James DiGiacomo - Petey Goldfeder
- Dat Phan - Slippy
- McKaley Miller - Eliza Montgomery
- Kevin Foster - Bad Guy #1
- Reign Edwards - Kitten
- Brandon Loeser - Alexander Garrett
- Scott Hoying - Scott Hoying
- Mitch Grassi - Mitch Grassi
- Kevin Olusola - Kevin Olusola
- Kirstin Maldonado - Kirstin Maldonado
- Matthew Sallee - Matthew Sallee
- Avi Kaplan - Avi Kaplan
- Peyton List - Emma Ross
- Cocoa Brown - Big Ange
- Vivian Lamolli - Abigail / Scar
- Lee Reherman - Victor
- Jonathan Schmock - Lloyd
- Natalija Nogulich - Margaret Vandervoort
- Erin Matthews - Sarah Andrews
- Telma Hopkins - Miss Holly
- Raven-Symoné - Simone Deveraux
- Chris Ellis - Christos Markos
- Skai Jackson - Zuri Ross
- Christopher O'Neal - River
- Arden Myrin - Candace Adams
- Patrick Cassidy - Chuck Maddox
- Michelle Noh - Maggie Summers
- George Wallace - Poppa Earl
- Cait Fairbanks - Ursula Timmcoy
- Chris Tavarez - Darien
- Rico E. Anderson - Coach
- Yetide Badaki - Penelope Brustorm
- Jason Downs - Agent Graham Brustorm
- Marcus Folmar - Joey
- Jill Remez - Mrs. Gutierre
- Kara Royster - Abby Martin
- Jasmine Guy - Erica King
- Tyler Poelle - Agent Gibb
- Robert Gant - Jackson Cleveland
- Michael McCafferty - Todd Clint
- Kevin Csolak - Adam
- Florence Henderson - Irma
- Natalie Lander - Darci
- Zendaya
Zendaya hace el papel de K.C. Cooper.
Veronica Dunne hace el papel de Marisa Miller.
Kamil McFadden interpreta a Ernie Cooper en la serie.
Trinitee interpreta a Judy Cooper en la serie.
Tammy Townsend interpreta a Kira Cooper en la serie.
Kadeem Hardison interpreta a Craig Cooper Jr. en la serie.
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