- Tom Kenny - Carl Chryniszzswics (voice)
- Tom Kenny - Alligator / Salesman / Fish (voice)
- Dionne Warwick - Self (voice)
- Casey Kasem - Shaggy Rogers (voice)
- Adam West - (voice)
- Cody Dorkin - Jungle Boy (voice)
- Heather North - Daphne Blake (voice)
- Jack Sheldon - Sensitive Male (voice)
- Jack Sheldon - Additional Voices (voice)
- Greg Burson - Ghostly Gardener (voice)
- Tia Carrere - Beautiful Woman / Female Elephant / Woman (voice)
- Brock Peters - Chronos (voice)
- Shaquille O'Neal - Shaquille O'Neal (voice)
- Seth Green - Seth Green (voice)
- Donny Osmond - Donny Osmond (voice)
- 'Weird Al' Yankovic - "Weird Al" Yankovic (voice)
- Dee Bradley Baker - Delivery Man / Wrinkled Grape Man / Brick Laying Pig (voice)
- Don Knotts - Don Knotts (voice)
- Gary Owens - Blue Falcon (voice)
- Mr. T - (voice)
- Richard Simmons - (voice)
- Luke Perry - (voice)
- Farrah Fawcett - (voice)
- Julie Nathanson - Miss Winkleman (voice)
- Julie Nathanson - Model (voice)
- Frank Welker - Fred Jones / Speed Buggy (voice)
- Frank Welker - Barney Rubble / Dino (voice)
- Julie McWhirter - (voice)
- Arlene Golonka - (voice)
- B.J. Ward - Velma Dinkley (voice)
- Bob Joles - Mobster / Cowman #1 / Bear (voice)
- Maurice LaMarche - Pigeon #1 / Elk Boss / Cowman #2 (voice)
- Laraine Newman - Cow (voice)
- Melissa Peterman - Becky (voice)
- Jeff Bergman - Fred Flintstone / TV Anchor / Dino Coaster (voice)
- Brian Cummings - Carney / Random Man / Mastro Vac (voice)
- Grey DeLisle - Pebbles Flintstone (voice)
- Tress MacNeille - Wilma Flintstone / Samantha (voice)
- John Stephenson - Mr. Slate / Roller Coaster Operator (voice)
- Phil LaMarr - Construction Worker / Portly Grape Man / Fish (voice)
- Roger Rose - Pig / Bango / Male Host (voice)
- Tara Strong - Female Host / Red Hooded Woman / Goldilocks (voice)
- James Arnold Taylor - Sour Grape Man / Bean Man (voice)
- Miles Thompson
- Kara Vallow
Brock Peters hace el papel de Chronos (voice).
Greg Burson hace el papel de Ghostly Gardener (voice).
Jeff Bennett interpreta a Johnny Bravo (voice) en la serie.
Brenda Vaccaro interpreta a Bunny Bravo (voice) en la serie.
Mae Whitman interpreta a Little Suzy (voice) en la serie.
Tom Kenny interpreta a Carl Chryniszzswics (voice) en la serie.
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