- Amy Farrington - Mrs Devlin
- Amy Farrington - Ms. Devlin
- Stephanie Beatriz - Salma Espinoza
- Tom Parker - River Stevens
- Haley Tju - Eileen Miller
- Ross Lynch - Austin Moon
- Devan Leos - Trevor
- Nathaniel J. Potvin - Shane
- Sierra McCormick - Connie Thompson
- Genevieve Hannelius - Mackenzie
- Lombardo Boyar - Boomer
- Austin North - Logan Watson
- Spencer Boldman - Ted Hoover
- Jace Norman - Finch
- Jack Griffo - Brett Summers
- Noah Centineo - Rick Larkin
- Brian Stepanek - Mr. Collinsworth
- Stefanie Scott - Maybelle
- Chris Bosh - Himself
- John DeLuca - McD
- Suzanne Krull - Mildred Lumpkey
- Matt Cook - Mr. Feeley
- Genneya Walton - Nora
- Jaden Martin - Martin
- Bridgit Mendler - Teddy Duncan
- Jason Dolley - PJ Duncan
- Dana Daurey - Marcy
- Matthew Timmons - Max Bauer
- Cooper Barnes - Director
- Amanda Jane Cooper - Susan Channing
- Ray Ford - Harold
- Garrett Clayton - Earl
- L.J. Johnson - Ms. Kruchall
- Deven MacNair - Vanessa Colson / The Mauler
- Rachel Germaine - Corinne Baxter
- Lily Mae Harrington - Delilah
- Roger Bart - Mr. Phil McNichol
- Stephen Guarino - James McMillan
- Isabella Crovetti - Wendy McMillan
- Jillian Rose Reed - Abbey
- Michelle Obama - Self
- Vernee Watson-Johnson - Mrs. Harris
- Kyla-Drew - Taylor Harris
- Yvette Saunders - Sergeant Harris
- Kurt Ela - Beau Jones
- John Rubinstein - Ivan
- Greg Thirloway - Eric Booth
- Lauren Benz Phillips - Alexia
- Adam Sandler - Self
- Lenny Jacobson - Ted the Delivery Guy
- Jackson Odell - Gale
- Lainie Kazan - Wanda Winkle
- Shanna Strong - Shelby
- Evan Roe - Billy
- Joey Bragg - Joey Rooney
- Tenzing Norgay Trainor - Parker Rooney
- Laura Marano - Ally Dawson
- Raini Rodriguez - Trish De la Rosa
- Calum Worthy - Dez
- Hina Abdullah - Kami
- Kevin Symons - Professor Fisk
- Nadji Jeter - Terry
- Matt Shively - Hudson
- Francesca Capaldi - Madeline
- Blake Cooper Griffin - Scott
- Raymond Lee - Clifford
- Napoleon Ryan - Roger Bevans
- Meaghan Jette Martin - Delphina
- Deniz Akdeniz - Marco
- Nikki Hahn - Lindsay
- Sarah Gilman - Delia Delfano
- Garrett Backstrom - Vincent
- John Fleck - Robert R.J. Roberts
- Meshach Taylor - Grimm Haloran
- Laura Spencer - Cassandra
- Kevin Michael Martin - Malcolm
- Sandra Purpuro - Carmella Ciccolini
- Jimmy Smagula - Angelo Ciccolini
- Robert Picardo - Cyril Lipton
- Kelly Gould - Rosie
- Cheri Oteri - Mrs. Falkenberg
- Patrick Kerr - Clement Brulee
- Lauren Pritchard - Coach Penny
- Oliver Muirhead - Nigel Pettigrew
- Marlowe Peyton - Madge
- Josie Totah - Stuart Wooten
- Katherine McNamara - Bryn Breitbart
- Lulu Antariksa - Victoria 'Vic' Montesano
- Molly Shannon - Beverly Shannon
- Kate Flannery - Corporal Cookie
- James Patrick Stuart - John Wayne 'J.W.' Prescott
- Molly Burnett - Darla Shannon
- Dylan Boyack - Caleb Shannon
- John Michael Higgins - Carlisle
- Pierson Fodà - Brooks Wentworth
- Jennifer Veal - Agatha
- Jennifer Veal - Agatha / Angela
- Bob Bledsoe - Mort Marty
- Chris Wylde - Grover
- Maia Mitchell - Shaylee Michaels
- Amy Hill - Keahi
- Wayne Wilderson - Kevin Randolf
- Ava Penner - Jasmine Epstein
- Arvie Lowe, Jr. - J.J. Mayfield
- Jo Anne Worley - Nana Banana
- Debbie Lee Carrington - Jingles
- Adam Kulbersh - Clerk
- Lachlan Buchanan - Jordan Taylor
- Carolyn Hennesy - Rhoda Chesterfield
- Ben Bledsoe - Brody Hinton
- Max Charles - Axel
- Maia Madison - Samantha
- Grace Kaufman - Tanya Weston
- Eric Petersen - Dr. Cyrus Van Adams
- Christina Moore - Christina Ross
- Charles Esten - Morgan Ross
- Joey Richter - Officer Petey
- Travis Wester - Chef Rolando
- Izzy Palmieri - Rachel Kapowski
- Poppy - Student (uncredited)
- Brian Carpenter - Head Judge
- Bryan Okes - A.D.
- Mia Talerico - Charlie Duncan
- Samantha Boscarino - Skyler
- Leigh-Allyn Baker - Amy Duncan
- Bradley Steven Perry - Gabe Duncan
- Eric Allan Kramer - Bob Duncan
- Susie Francis Gunter
- Sheryl Levine
- Stefen Maekawa
- Penny Segal
- Lorie Carter
- Pamela Eells
- Adam I. Lapidus
- John Adair
- Steve Hampton
- John Bickelhaupt
- Joshua E. Schneider
Debby Ryan interpreta a Jessie Prescott en la serie.
Peyton List interpreta a Emma Ross en la serie.
Cameron Boyce interpreta a Luke Ross en la serie.
Karan Brar interpreta a Ravi Ross en la serie.
Skai Jackson interpreta a Zuri Ross en la serie.
Kevin Chamberlin interpreta a Bertram Winkle en la serie.
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