- Tommy Duggan - Mr. Prescott
- Eileen Way - Mama Carlucci
- Kathleen Byron - Nurse Lemoine
- Moira Redmond - Maureen Delaney / Mary Dolan
- Francis de Wolff - The General
- Burt Kwouk - Jimmy Hau
- Stuart Nichol - Bradford
- Michael Bilton - Evan Prosser
- Meier Tzelniker - Herman Hartz
- Vincent Ball - Joplin
- Jan Holden - Helen Madison
- Eric Pohlmann - Abul Kemal Pasha
- Steve Plytas - Captain Quiroga
- Peter McEnery - Alan Vernon
- Hana Maria Pravda - The Woman
- André Morell - Howard Conway
- Alfred Burke - Mr. Molinsky
- Lee Patterson - Frank Carroll
- John Bay - 1st Reporter
- Mark Dignam - Geoffrey Redding
- Ronan O'Casey - Ralph Barnaby
- Paul Whitsun-Jones - Cesar Calve
- John Turner - Tony Stanton
- Griffith Jones - Mr. Gryffyd
- Lionel Murton - Captain Davis
- George Pastell - Baron Constantine
- Bernard Cribbins - Pasquale
- Alec Mango - Emir Yussef Raschid
- George Roderick - Manuel Barbarus
- Ferdy Mayne - Baron Rainis
- Marne Maitland - Inspector Rabat
- Nadja Regin - Nora Galloway
- Hildegard Knef - Brenda Carrington
- Neil McCallum - Chet Lawton
- George Mikell - Lempfert
- George Mikell - Lampfert
- Joyce Carey - Grand Duchess Marowska
- Joyce Carey - Mrs. Livingstone
- Harold Kasket - Bertinoro
- Harold Kasket - Gustave Vigo
- John Lee - Jeff Morgan
- Stratford Johns - The Registrar
- Maxine Audley - Michele Di Fontana
- Maxine Audley - Countess Bernaise
- Cyril Shaps - Lombardi
- Kevin Stoney - Huw Gryffyd
- Francis Matthews - Paul Medina
- Francis Matthews - Aldo Forenza
- Tim Turner - David Ross
- Edwin Richfield - Charlie Bismarck
- Monte Landis - Sami Kharan
- William Franklyn - Larry Sullivan
- William Franklyn - Conrad Schneider
- Vera Fusek - Catalina
- Bessie Love - Marta Steibel
- Bessie Love - Mrs. Morgan
- Terence Longdon - Mr. Gordon
- John Slater - Ziggy Mazagan
- Denis Shaw - Victor Prado
- Denis Shaw - Horse Carlucci
- Arnold Diamond - Chaumont
- Julia Arnall - Hilda Brenner
- Anthony Dawson - Gilles Porret
- Yvonne Romain - Lucretia Risi
- Yvonne Romain - Maria Carola
- Peter Dyneley - Len Hickman
- Lisa Gastoni - Monette
- Lisa Gastoni - Denise De Montceau
- Derek Francis - Emlyn
- Nigel Green - Montoro
- John Abineri - The Warder
- Peter Sallis - Eugene Payas
- Elizabeth Wallace - Donna Alicia
- Avice Landone - Baroness Rainis
- Millicent Martin - Katie O'Brien
- Millicent Martin - Susan
- Robert O'Neil - Paul Orlando
- Robert O'Neil - Jackie Barnaby
- David L. Lander - The Gendarme
- Dermot Kelly - O'Grady
- Willoughby Goddard - Inspector Pilsen
- Liane Aukin - Maria Martos
- Neil McCarthy - Studs Lubeck
- Lisa Daniely - Lisa
- Robert Arden - McNaughton
- Marius Goring - Ferdie Steibel
- Patrick Allen - Lieutenant Larkin
- Peter Illing - Henry Raffael
- Peter Illing - Ali Zhodar
- Bobby Ghisays - Milkman
- Alan Gifford - Buck Guthrie
- Alan Gifford - Lindsay Somerset
- Ruth Gower - Schoolmistress
- David Graham - Laboratory Man
- Patrick Troughton - Silversmith
- Patrick Troughton - Bela Davos
- Bruno Barnabe - Jacotinski
- Bruno Barnabe - The Policeman
- Simone Lovell - Librarian
- Robert Perceval - Bank Manager
- John Stone - Inspector
- David Stuart - Detective
- A. Edward Sutherland
Neil McCarthy interpreta a Studs Lubeck en la serie.
Art Fleming interpreta a Ken Franklin en la serie.
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