- Philip Jackson - Chief Inspector James Harold Japp
- Philip Jackson - Assistant Commissioner Japp
- Emily Blunt - Linnet Ridgeway
- Alex Jennings - Dr. Roberts
- Aidan Gillen - Amyas Crale
- Brigit Forsyth - Mrs. Todd
- Dermot Crowley - Arthur Simpson
- Freda Dowie - Eliza Dunn
- Antony Carrick - Mr. Todd
- Katy Murphy - Annie
- Tom Mison - David Baker
- Aidan McArdle - Stephen Norton
- Sasha Behar - Pilar
- Rowena Cooper - Sarah Siddaway
- Juliette Mole - Jane Plenderleith
- James Faulkner - Major Eustace
- Gabrielle Blunt - Mrs. Pierce
- Geoffrey Bateman - Marcus Waverly
- Julia Chambers - Ada Waverly
- Patrick Jordan - Tredwell
- Carol Frazer - Jessie Withers
- Sandra Freeman - Miss Collins
- Robert Putt - Rogers
- Tony Aitken - Tommy Pinner
- Charles Pemberton - Stooge
- Charles Pemberton - Harry Clarke
- Denys Hawthorne - Bonnington
- Clifford Rose - Makinson
- Hilary Mason - Mrs. Hill
- Cheryl Hall - Molly
- Suzanne Burden - Patricia Matthews
- Nicholas Pritchard - Donovan
- Robert Hines - Jimmy
- Amanda Elwes - Mildred
- Josie Lawrence - Mrs. Grant
- Alan Partington - Inspector Flint
- Angela Down - Marjorie Gold
- Timothy Kightley - Major Barnes
- Frances Low - Pamela Lyall
- Jon Cartwright - Commander Chantry
- Annie Lambert - Valentine Chantry
- Peter Settelen - Douglas Gold
- Victoria Hasted - Pamela Cregan
- Roger Hume - General Forbes
- Ben Aris - Captain Fowler
- Dorothea Phillips - Nelly Morgan
- John Normington - Colonel John Clapperton
- Sheila Allen - Mrs. Clapperton
- Ann Firbank - Ellie Henderson
- James Ottaway - Mr. Russell
- John Stride - Tommy Mayfield
- Carmen du Sautoy - Mrs. Vanderlyn
- Ciaran Madden - Lady Mayfield
- Guy Scantlebury - Reggie Carrington
- Albert Welling - Carlile
- Dan Hildebrand - Chauffeur
- Niamh Cusack - Valerie Saintclair
- David Swift - Henry Reedburn
- Jonathan Coy - Bunny Saunders
- Jack Klaff - Prince Paul of Maurania
- Gawn Grainger - Ralph Walton
- Avril Elgar - Mrs. Oglander
- Abigail Cruttenden - Geraldine Oglander
- Alan Howard - Benedict Farley / Hugo Cornworthy
- Joely Richardson - Joanna Farley
- Mary Tamm - Mrs. Farley
- Martin Wenner - Herbert Chudley
- Paul Lacoux - Dr. Stillingfleet
- Polly Walker - Magdala 'Nick' Buckley
- Jeremy Young - Bert Croft
- Mary Cunningham - Ellen
- Paul Geoffrey - Jim Lazarus
- Christopher Baines - Charles Vyse
- Carol MacReady - Milly Croft
- Godfrey James - Inspector
- Terence Harvey - Lavington
- Carole Hayman - Mrs. Godber
- Tony Stephens - Sergeant
- Lloyd McGuire - Museum Guard
- Anthony Bate - Lord Pearson
- Colin Stinton - Charles Lester
- James Saxon - Reggie Dyer
- Vincent Wong - Chinaman
- Richard Albrecht - Lobby Clerk
- Gloria Connell - Miss Devenish
- Julian Firth - Bank Teller
- Vanessa Kirby - Celia Ravenscroft
- Chloe Salaman - Freda Stanton
- John Bowler - Jacob Radnor
- Jerome Willis - Edward Pengelley
- Amanda Walker - Mrs. Pengelley
- Tilly Vosburgh - Jessie Dawlish
- Beth Goddard - Sister Agnieszka
- Beth Goddard - Violet Wilson
- Derek Benfield - Dr. Adams
- Laura Girling - Edwina Marks
- John Rowe - Prosecutor
- Mel Martin - Charlotte Davenheim
- Kenneth Colley - Mathew Davenheim
- Tony Mathews - Gerald Lowen
- Fiona McArthur - Maid
- Richard Beale - Merritt
- Barbara Barnes - Mrs Lester
- Barbara Barnes - Mrs. Leidner
- Bob Mason - Sergeant
- Jessica Chastain - Mary Debenham
- Kelly Reilly - Mary Gerrard
- Jemima Rooper - Norma Restarick
- Clemency Burton-Hill - Claudia Reece-Holland
- Matilda Sturridge - Frances Cary
- James Wilby - Andrew Restarick
- Peter Bowles - Sir Roderick Horsfield
- Lucy Liemann - Sonia
- Shaun Dingwall - Doctor Franklin
- Helen Baxendale - Elizabeth Cole
- Anne Reid - Daisy Luttrell
- John Standing - Colonnel Toby Luttrell
- Philip Glenister - Sir William Boyd Carrington
- Alice Orr-Ewing - Judith Hastings
- Matthew McNulty - Maggiore Allerton
- Anna Madeley - Barbara Franklin
- Claire Keelan - Nurse Craven
- Ron Berglas - Dr. Leidner
- Dinah Stabb - Anne Johnson
- Georgina Sowerby - Amy Leatheran
- Pandora Clifford - Sheila Maitland
- Christopher Bowen - Richard Carey
- Iain Mitchell - Superintendent Maitland
- Sean Pertwee - Ronnie Oglander
- Sean Pertwee - Sir George Stubbs
- Alexi Kaye Campbell - Joseph Mercado
- Hichem Rostom - Hotel Receptionist
- Kamel Touati - Squat Man
- Lesley Manville - Mrs. Lorrimer
- Lyndsey Marshal - Miss Meredith
- Honeysuckle Weeks - Miss Dawes
- Tristan Gemmill - Major Despard
- Robert Pugh - Colonel Hughes
- Alexander Siddig - Shaitana
- David Westhead - Supt. Jim Wheeler
- Lindsay Duncan - Lady Tamplin
- James D'Arcy - Derek Kettering
- Jaime Murray - Ruth Kettering
- Georgina Rylance - Katherine
- Roger Lloyd Pack - Inspector Caux
- Josette Simon - Mirelle Milesi
- Alice Eve - Lenox
- Bronagh Gallagher - Ada Mason
- Elliott Gould - Rufus Van Aldin
- John Carson - Sir George Carrington
- John Carson - Richard Abernethie
- Vernon Dobtcheff - Simeon Lee
- Simon Roberts - Alfred Lee
- Catherine Rabett - Lydia
- Eric Carte - George
- Andrée Bernard - Magdalene
- Brian Gwaspari - Harry
- Mark Tandy - Sugden
- Olga Lowe - Stella
- Ayub Khan-Din - Horbury
- John Horsley - Tressilian
- Scott Handy - Young Simeon
- Helen Grace - Jane Wilkinson
- John Castle - Lord Edgware
- Fiona Allen - Carlotta Adams
- Dominic Guard - Bryan Martin
- Deborah Cornelius - Penny Driver
- Hannah Yelland - Geraldine Marsh
- James Fox - Colonel Race
- Emma Griffiths Malin - Jacqueline De Bellefort
- JJ Feild - Simon Doyle
- Judy Parfitt - Miss Van Schuyler
- Daisy Donovan - Cornelia Robson
- Barbara Flynn - Mrs Allerton
- Tim Curry - Lord Boynton
- Christina Cole - Sarah
- Elizabeth McGovern - Dame Celia Westholme
- Cheryl Campbell - Lady Boynton
- Zoe Boyle - Jinny Boynton
- Emma Cunniffe - Carol Boynton
- Angela Pleasence - Nanny
- Paul Freeman - Col. Carbury
- Christian McKay - Jefferson Cope
- John Hannah - Dr. Gerard
- Bill Thomas - Steward
- Mark Chapman - PC Keating (uncredited)
- Michael Higgs - Patrick Redfern
- Tamzin Malleson - Christine Redfern
- Louise Delamere - Arlena Stuart
- Tim Meats - Stephen Lane
- Carolyn Pickles - Emily Brewster
- David Mallinson - Kenneth Marshall
- Russell Tovey - Lionel Marshall
- Marsha Fitzalan - Rosamund Darnley
- Ian Thompson - Major Barry
- Rebecca Johnson - Gladys Narracott
- Christopher Eccleston - Frank Carter
- Steven Pacey - Stephen Paynter
- Siân Phillips - Mrs. Laura Upward
- Mark Gatiss - Leonard Boynton
- Michael Fassbender - George Abernethie
- Zoë Wanamaker - Ariadne Oliver
- Peter Capaldi - Claude Langton
- Rachael Stirling - Caroline Crale
- David Timson - Horace Blatt
- Toby Stephens - Philip Blake
- Rosalind March - Mrs. Castle
- Marc Warren - Meredith Blake
- Haydn Gwynne - Coco Courtenay
- Haydn Gwynne - Miss Battersby
- Aimee Mullins - Lucy Crale
- Jason Davies - Nathan Lloyd
- Julie Cox - Elsa Greer
- Paul Ready - William
- Gemma Jones - Miss Williams
- Harriet Eastcott - Librarian
- Grant Gillespie - Jack Lovett
- Sophie Winkleman - Angela Warren
- Talulah Riley - Young Angela
- Melissa Suffield - Young Lucy
- Patrick Malahide - Montague Depleach
- Jonathan Cake - John Christow
- Megan Dodds - Henrietta Savernake
- Sarah Miles - Lucy Angkatell
- Macy Nyman - Joyce Reynolds
- Edward Fox - Gudgeon
- Claire Price - Gerda Christow
- Olivia Jewson - School Girl
- Lysette Anthony - Veronica Cray
- Tom Georgeson - Inspector Grange
- Edward Hardwicke - Henry Angkatell
- Caroline Martin - Midge Hardcastle
- Jamie de Courcey - Edward Angkatell
- Ian Talbot - Victor Simms
- Angela Curran - Frances Simms
- Lucy Briers - Beryl Collins
- Daniel Lapaine - Tim Allerton
- Frances de la Tour - Salome Otterbourne
- Zoe Telford - Rosalie Otterbourne
- Steve Pemberton - Dr Bessner
- Alastair Mackenzie - Ferguson
- David Soul - Andrew Pennington
- Elisabeth Dermot Walsh - Elinor Carlisle
- Rupert Penry-Jones - Roddy Winter
- Paul McGann - Dr. Peter Lord
- Phyllis Logan - Nurse Hopkins
- Marion O'Dwyer - Nurse O'Brien
- Diana Quick - Mrs. Welman
- Stuart Laing - Ted Horlick
- Robert Bathurst - Gilbert Entwhistle
- John Cording - Jameson
- Anna Calder-Marshall - Maude Abernethie
- Fiona Glascott - Rosamund
- Geraldine James - Helen Abernethie
- Dominic Jephcott - Dr. Larraby
- Lucy Punch - Janet
- Kevin Doyle - Inspector Morton
- Julian Ovenden - Michael Shane
- Monica Dolan - Miss Gilchrist / Cora Gallaccio
- Benjamin Whitrow - Timothy Abernethie
- Anthony Valentine - Giovanni Gallaccio
- Danny Webb - Porter
- Brian Poyser - Salvation Army Speaker
- Phillip Manikum - Police Sergeant
- Barrie Cookson - Dr. Brett
- Beccy Wright - Maid
- Chris Gordon - Bickford
- Richard Dixon - Henden
- Sinéad Cusack - Mrs. Amy Folliat
- Rebecca Front - Miss Brewis
- Francesca Zoutewelle - Dutch Girl Hiker
- Stephanie Leonidas - Hattie Stubbs
- Sam Kelly - John Merdell
- Martin Jarvis - Captain Warburton
- Rosalind Ayres - Mrs. Warburton
- Emma Hamilton - Sally Legge
- Daniel Weyman - Alec Legge
- Elliot Barnes-Worrell - Etienne De Souza
- Nicholas Woodeson - Detective Sergeant Hoskins
- Tom Ellis - Detective Inspector Bland
- Angel Witney - Gertie Tucker
- Alexandra Dowling - Marie
- John Harding - Commander George Challenger
- Tom Wlaschiha - Schwartz
- Pauline Jameson - Isabel Tripp
- Jonathan Newth - Dr Grainger
- Norma West - Wilhemina
- David Lloyd - Museum Attendant
- Trevor Cooper - Ed Opalsen
- Sorcha Cusack - Margaret Opalsen
- Karl Johnson - Saunders
- Elizabeth Rider - Grace
- Hermione Norris - Celestine
- Iain Cuthbertson - Gervase Chevenix
- Emma Fielding - Ruth Chevenix
- Fiona Walker - Miss Lingard
- Zena Walker - Vanda Chevenix
- Jeremy Northam - Hugo Trent
- Tushka Bergen - Susan Cardwell
- James Greene - Snell
- Mark Crowdy - Viscount Cronshaw
- David Henry - Eustace Beltaine
- Nathaniel Parker - Chris Davidson
- Kate Harper - Mrs Mallaby
- Andrew Burt - James Ackerley
- Charles Collingwood - BBC Announcer
- Brian Mitchell - Second Actor
- Sarah Crowden - Receptionist
- Bryan Matheson - Butler
- Frederick Treves - Colonel Lacey
- Stephanie Cole - Mrs Lacey
- David Howey - Jesmond
- Phyllida Law - Lady Carrington
- Phyllida Law - Mrs Llewellyn-Smythe
- Tariq Alibai - Prince Farouk
- Helena Michell - Sarah Lacey
- John Vernon - David Welwyn
- Nigel Le Vaillant - Desmond Lee-Wortley
- Robyn Moore - Gloria
- John Dunbar - Peverill
- Jonathan R. Scott - Colin
- Edward Holmes - Michael
- Susan Field - Mrs Ross
- John McEnery - Colonel Curtiss
- Caroline Langrishe - Marguerite Clayton
- Malcolm Sinclair - Edward Clayton
- Antonia Pemberton - Lady Chatterton
- Peter Copley - Burgoyne
- Sam Smart - Smithy
- Edward Clayton - Rouse
- Metin Yenal - Umpire
- Victoria Scarborough - Party Dancer
- Frances Barber - Merlina Rival
- Frances Barber - Lady Millicent
- Christopher Lamb - Party Dancer
- Damian Lewis - Leonard Bateson
- Jonathan Firth - Nigel Chapman
- Polly Kemp - Patricia Lane
- Sarah Badel - Florence Hubbard
- Rachel Bell - Mrs Nicoletis
- Granville Saxton - Mr Casterman
- David Burke - Sir Arthur Stanley
- Bernard Lloyd - Mr Endicott
- Paris Jefferson - Sally Finch
- Gilbert Martin - Colin McNabb
- Diane Fletcher - Eloise Renauld
- Nicholas Farrell - Donald Fraser
- Nicholas Farrell - Knighton
- Damien Thomas - Paul Renauld
- Ben Pullen - Jack Renauld
- Kate Fahy - Bernadette Daubreuil
- Sophie Linfield - Marthe Daubreuil
- Jacinta Mulcahy - Bella Duveen
- Terence Beesley - Stonor
- Bill Moody - Giraud
- Bernard Latham - Bex
- Andrew Melville - Dr Hautet
- Henrietta Voigts - Leonie
- James Vaughan - Adam Letts
- Rolf Saxon - Dr. Ames
- Olivier Pierre - Henry Schneider
- Jon Strickland - Dr. Fosswell
- Bill Bailey - Felix Bleibner
- Paul Birchard - Rupert Bleibner
- Simon Cowell-Parker - Nigel Harper
- Grant Thatcher - Sir Guy Willard
- Anna Cropper - Lady Willard
- Mozaffar Shafeie - Hassan
- Peter Reeves - Sir John Willard
- Robert Wisdom - Waiter
- Rupert Evans - Harold Waring
- Lorna Nickson Brown - Lucinda Le Mesurier
- Stephen Frost - Chief Inspector
- Isobel Middleton - Policewoman
- Tom Chadbon - Dr. Burton
- Tom Austen - Ted Williams
- Fiona O'Shaughnessy - Katrina
- Nicholas McGaughey - Inspector Lementeuil
- Morven Christie - Elsie Clayton
- Sandy McDade - Mrs. Rice
- Orla Brady - Countess Rossakoff
- Nigel Lindsay - Francesco
- Richard Katz - Gustave
- Simon Callow - Dr. Lutz
- Eleanor Tomlinson - Alice Cunningham
- Tom Brooke - Tysoe
- Nicholas Day - Ingles
- James Carroll Jordan - Abe Ryland
- Patricia Hodge - Madame Olivier
- Simon Lowe - Dr. Quentin
- Michael Culkin - Savaranoff
- Lou Broadbent - Mabel
- Sarah Parish - Flossie Monro
- Peter Symonds - Jonathan Whalley
- Barbara Kirby - Mrs. Andrews
- Nicholas Burns - Inspector Meadows
- Alex Palmer - Robert Grant
- Teresa Banham - Diana Paynter
- Jack Farthing - Gerald Paynter
- Oliver Ford Davies - Dr. Sheppard
- Malcolm Terris - Roger Ackroyd
- Selina Cadell - Caroline Sheppard
- Daisy Beaumont - Ursula Bourne
- Flora Montgomery - Flora Ackroyd
- Nigel Cooke - Geoffrey Raymond
- Patrick Ryecart - Sir Anthony Morgan
- Patrick Ryecart - Charles
- Jamie Bamber - Ralph Paton
- Roger Frost - Parker
- Vivien Heilbron - Mrs. Ackroyd
- Gregor Truter - Inspector Davis
- Rosalind Bailey - Mrs. Ferrars
- Liz Kettle - Mrs. Folliott
- Charles Simon - Hammond
- Chas Early - Constable Jones
- Graham Chinn - Landlord
- Clive Brunt - Naval Officer
- Phil Atkinson - Ted
- Mark Kingston - Andrew Marsh
- Susan Tracy - Phyllida Campion
- Gillian Hanna - Margaret Baker
- Terrence Hardiman - John Siddaway
- Jon Laurimore - Walter Baker
- Pip Torrens - Major Rich
- Pip Torrens - Jeremy Cloade
- Edward Atterton - Robert Siddaway
- Neil Stuke - Peter Baker
- Stephen Oxley - Doctor
- Scott Cleverdon - President
- Leonard Preston - Mr. Graves
- Anna Mazzotti - Margherita Fabbri
- David Neal - Bruno Vizzini
- Vincent Riotta - Mario Ascanio
- Sidney Kean - Count Foscatini
- Arthur Cox - Dr. Hawker
- Vittorio Amandola - 1st Secretary
- David Verrey - Chef
- Janet Lees-Price - Miss Rider
- David Willoughby - Lad
- Ann Morrish - Emily Arundel
- Kate Buffery - Theresa
- Paul Herzberg - Jacob
- Julia St. John - Bella
- Muriel Pavlow - Julia Tripp
- Pat O'Toole - Sarah
- Geoffrey Freshwater - Sgt Keeley
- Richard Bebb - Newsreader (voice)
- Richard Bebb - Mr. Cameron
- Richard Bebb - News Commentator
- Tobias Saunders - Alexis
- Layla Harrison - Katya
- Stephen Tomlin - Vicar
- Tim Williams - American
- Sarah Stephenson - Mrs Finch
- Geoffrey Banks - Starter
- Tim Steed - Ronald Marsh
- Lesley Nightingale - Miss Carroll
- Christopher Guard - Alton
- Iain Fraser - Donald Ross
- Tom Beard - Duke of Merton
- Virginia Denham - Alice
- John Quentin - Sir Montagu Corner
- Janet Hargreaves - Lady Corner
- Mark Brignal - Addison
- John Hart Dyke - Thompson
- Jonathan Aris - Receptionist
- Richard Durden - Pebmarsh
- Richard Durden - Dr. Pritchard
- Annette Badland - Mrs. Spriggs
- Roger Brierley - Judge
- Philip Anthony - Doctor
- Philip Anthony - Vicar
- Richard Teverson - Hollinghurst
- Jack Galloway - Marsden
- Geoffrey Beevers - Seddon
- Alistair Findlay - Prosecuting Counsel
- Linda Spurrier - Mrs. Bishop
- Ian Taylor - Shopkeeper
- Timothy Carlton - Judge
- Louise Callaghan - Hunterbury Maid
- Olivia Grant - Annabel Larkin
- Anna Skellern - Fiona Hanbury
- Tom Burke - Lt. Colin Race
- Andrew Havill - Sven Hjerson
- Victoria Wicks - Mrs. Swinburne
- Jaime Winstone - Sheila Webb
- Greta Scacchi - Mrs. Burton-Cox
- Iain Glen - Doctor Willoughby
- David Yelland - George
- David Yelland - Laverton West
- Toby Jones - Samuel Ratchett
- Brian J. Smith - Hector MacQueen
- David Morrissey - John Arbuthnot
- Eileen Atkins - Princess Dragomiroff
- Susanne Lothar - Hildegarde Schmidt
- Denis Ménochet - Pierre Michel
- Barbara Hershey - Caroline Hubbard
- Hugh Bonneville - Edward Masterman
- Marie-Josée Croze - Greta Ohlsson
- Stanley Weber - Count Andrenyi
- Elena Satine - Countess Andrenyi
- Joseph Mawle - Antonio Foscarelli
- Samuel West - Dr. Constantine
- Kate Ashfield - Miss Wills
- Jane Asher - Lady Mary
- Tom Wisdom - Oliver Manders
- Katie Leung - Hsui Tai
- Richard Dillane - Major Summerhayes
- Jenny Agutter - Adela Marchmont
- Patrick Baladi - Rowley Cloade
- Eva Birthistle - Rosaleen / Eileen
- Elliot Cowan - David Hunter
- Amanda Douge - Lynn Marchmont
- Penny Downie - Frances Cloade
- Claire Hackett - Beatrice Lippincott
- Celia Imrie - 'Aunt' Kathy Cloade
- Fenella Woolgar - Ellis
- Fenella Woolgar - Miss Whittaker
- Nicholas Le Prevost - Major James Porter
- Tim Pigott-Smith - Dr. Lionel Woodward
- Elizabeth Spriggs - Mrs. Leadbetter
- Tim Woodward - Enoch Arden / Charles
- Rosalie Crutchley - Madame Deroulard
- Anna Chancellor - Virginie Mesnard
- David de Keyser - Gaston Beaujeu
- Jonathan Hackett - Claude Chantalier
- Geoffrey Whitehead - Xavier St. Alard
- Mark Eden - Boucher
- Jonathan Barlow - Jean-Louis Ferraud
- James Coombes - Paul Deroulard
- Preston Lockwood - Francois
- Linda Broughton - Denise
- Lucy Cohu - Marianne Deroulard
- David Troughton - Barton Russell
- Dorian Healy - Anthony Chapell
- Geraldine Somerville - Pauline Weatherby
- Yolanda Vazquez - Lola
- Robin McCaffrey - Iris Russell
- Hugh Ross - Stephen Carter
- Joseph Long - Luigi
- Ann Bell - Lady Astwell
- Adie Allen - Lily
- Denis Lill - Sir Reuben
- Jonny Phillips - Charles
- Bill Wallis - Horace Trefusis
- Ian Gelder - Victor Astwell
- Rosalind Knight - Georgina Morley
- Joanna Phillips-Lane - Gerda / Helen
- Peter Blythe - Blunt
- Sarah Woodward - Jane Grey
- Donald Sumpter - Cust
- Donald Douglas - Franklin Clarke
- Pippa Guard - Megan Barnard
- Diana Kent - Zoe Havering
- Jim Norton - Roger Havering
- Simon Shepherd - Andrew Hall
- Simon Shepherd - Dr Rendell
- Kika Markham - Countess Vera Rossakoff
- David Bamber - Bernard Parker
- Ian McCulloch - Jonathan Maltravers
- Geraldine Alexander - Susan Maltravers
- Alastair Duncan - Captain Black
- Richard Lintern - Guy Carpenter
- Richard Lintern - John Lake
- Martin Turner - John Harrison
- Kenneth Haigh - McKenzie
- Steven Mackintosh - Newsboy
- Julian Wadham - Rupert Carrington
- Samantha Bond - Stella Robinson
- William Hootkins - FBI Agent Burt
- Amelia Bullmore - Judith Butler
- Deborah Findlay - Rowena Drake
- Sophie Thompson - Mrs Reynolds
- Georgia King - Frances Drake
- Ian Hallard - Edmund Drake
- Timothy West - Reverend Cottrell
- Paola Dionisotti - Mrs Goodbody
- Julian Rhind-Tutt - Michael Garfield
- Paul Thornley - Inspector Raglan
- Vera Filatova - Olga Seminoff
- Eric Sykes - Mr Fullerton
- Sinéad Keena - Nora Brent
- Lesley Sharp - Miss Martindale
- Anna Massey - Miss Pebmarsh
- Phil Daniels - Inspector Hardcastle
- Ben Righton - Constable Jenkins
- Abigail Thaw - Rachel Waterhouse
- Guy Henry - Matthew Waterhouse
- Geoffrey Palmer - Vice Admiral Hamling
- Isabella Parriss - Jenny
- Tessa Peake-Jones - Val Bland
- Jason Watkins - Joe Bland
- Stephen Boxer - Christopher Mabbutt
- Andrew Forbes - Professor Purdy
- Greg Bennett - Plain Clothed Detective (uncredited)
- Martin Shaw - Sir Charles Cartwright
- Kimberley Nixon - Egg
- Art Malik - Sir Bartholomew Strange
- Suzanne Bertish - Miss Milray
- Anastasia Hille - Cynthia Dacres
- Ronan Vibert - Captain Dacres
- Anna Carteret - Mrs Babbington
- Nigel Pegram - Reverend Babbington
- Michael Hobbs - Coroner
- Jodie McNee - Annie
- Tony Maudsley - Supt Crossfield
- Prue Clarke - Matron
- Kimberly Stewart - Doris (uncredited)
- John Warnaby - Inspector Nelson
- Caroline O'Neill - Nanny Lavinia Seagram
- Tim Stern - Alf Renny
- Simon Hill - Bus Ticket Inspector
- Tessa Bell-Briggs - Daphne the Waitress
- Sean Kingsley - Policeman
- Jade Longley - Young Norma Restarick
- Juliet Howland - Mary Restarick
- Melanie Jessop - Molly Deane
- John Boswall - Dr Belvedere
- Kate Lynn Evans - Mrs Henderson
- Serena Scott Thomas - Model Girl
- Hilary Tindall - Commere at Fashion Show
- Julian Forsyth - Waiter
- John Stone - Halliday
- Alfredo Michelson - Comte de la Rochefour
- Marion Bailey - Jane Mason
- Shelagh McLeod - Florence Carrington
- Leon Eagles - Bank Manager
- John Abbott - Detective
- Stephen Riddle - Barman
- Adrian McLoughlin - Station Official
- Nigel Makin - Reception Clerk
- Richard Vanstone - Richard Vanstone
- Robert Locke - Naval Officer
- Duncan Faber - Porter
- Peter Kelly - Lucky Len
- Marc Culwick - Young Man
- Vass Anderson - Frampton
- Cathy Murphy - Maid
- Jeffrey Harmer - Assistant Director
- Andrew Seear - Humphrey Naylor
- John Evitts - Parsons
- Charles Armstrong - Receptionist
- Cathryn Bradshaw - Mary Drower
- Nina Marc - Thora Grey
- David McAlister - Inspector Glen
- Vivienne Burgess - Lady Clarke
- Ann Windsor - Miss Merrion
- Michael Mellinger - Franz Ascher
- Miranda Forbes - Mrs. Turton
- Peter Penry-Jones - Superintendent Carter
- Lucinda Curtis - Mrs. Marbury
- Jeremy Hawk - Deveril
- Beatie Edney - Mrs Hemmings
- Beatie Edney - Mary Cavendish
- Allan Mitchell - Dr. Kerr
- Andrew Williamson - Man in Library
- John Breslin - Mr. Barnard
- Claude Close - Doncaster Sergeant
- Alex Knight - Andover Sergeant
- Campbell Graham - Mr. Downes
- Gordon Salkilld - Commissionaire
- Richard Hope - Supt. Harold Spence
- Richard Hope - Spence
- Norman McDonald - Mr. Strange
- Pat Gorman - Desk Sergeant (uncredited)
- John Crocker - Dr Graham
- Geoffrey Greenhill - Wilson
- Joe Bates - Alfred
- Fergus McLarnon - Hood
- Jenny Funnell - Nurse Andrews
- Janice Cramer - Maid
- David Quilter - Mr. Shaw
- Ewan Hooper - Mr. Vavasour
- Paul Young - Mr. McNeil
- Lizzy McInnerny - Nurse Long / Miranda Brooks
- Oliver Parker - Philip Ridgeway
- Natalie Ogle - Esmee Dalgleish
- Christopher Owen - Chief Purser
- Jonathan Stratt - Spivvy Passenger
- Dallas Adams - Hood
- Kieron Jecchinis - Tom Franklin
- Edward Phillips - Flower Seller
- Robin Hunter - Police Officer
- Anne Stallybrass - Mary Delafontaine
- Tim Wylton - Henry Delafontaine
- Margery Mason - Amelia Barrowby
- Peter Birch - Nicholai
- Ralph Nossek - Dr Sims
- John Burgess - Mr Harrison
- John Rogan - Pathologist
- Stephen Petcher - Photographer
- Philip Praeger - Police Constable
- Shaughan Seymour - Archie Havering
- Roy Boyd - Jack Stoddard
- Bernard Horsfall - Harrington Pace
- Victoria Alcock - Ellie
- Clare Travers-Deacon - Joan
- Christopher Scoular - Sergeant Forgan
- Raymond Trickitt - Constable Cooke
- Arthur Whybrow - Mr Anstruther
- Denyse Alexander - Mrs Middleton
- David Lyon - Marcus Hardman
- Charmian May - Lady Runcorn
- Nicholas Selby - Mr Johnstone
- Michael Packer - Redfern
- William Chubb - Blake
- Mark Fletcher - Constable
- Meriel Dickinson - Katherine Bird
- Yitkin Seow - Nacora
- Richard Ryan - Porter
- Anita Carey - Miss Rawlinson
- Desmond Barrit - Samuel Naughton
- Ralph Watson - Danvers
- Edward Jewesbury - Dr Bernard
- Geoffrey Swann - Police Sergeant
- Hilary Sesta - Doctor's Receptionist
- Pat Keen - Civil Defence Organiser
- David Rintoul - John Cavendish
- Gillian Barge - Mrs. Inglethorp
- Michael Cronin - Alfred Inglethorp
- Joanna McCallum - Evie Howard
- Anthony Calf - Lawrence Cavendish
- Allie Byrne - Cynthia Murdoch
- Lala Lloyd - Dorcas
- Michael Godley - Dr. Wilkins
- Morris Perry - Mr. Wells
- Penelope Beaumont - Mrs. Raikes
- David Savile - Summerhaye
- Tim Munro - Edwin Mace
- Tim Preece - Philips K.C.
- Merelina Kendall - Mrs. Dainty
- Bryan Coleman - Vicar
- Eric Stovell - Chemist
- Donald Pelmear - Judge
- Caroline Swift - Nurse
- Ken Robertson - Army Officer
- Michael Roberts - Tindermans
- Jeffrey Robert - Foreman of the Jury
- Robert Vowles - Hire Car Driver
- David Michaels - Soldier
- James Taylor - Waiter
- Michael Vaughan - Sergeant
- Brian McDermott - Chief Inspector
- John Michie - James Robinson
- Jemma Churchill - Elsie
- Peter Howell - Mr. Paul
- Jenifer Landor - Carla Romero
- Carolyn Colquhoun - Mabelle
- Catherine Russell - Katrina Reiger
- Catherine Russell - Pamela Horsfall
- Karen Gledhill - Gladys Neville
- Laurence Harrington - Henry Morley
- Sara Stewart - Jane Olivera
- Helen Horton - Julia Olivera
- Kevork Malikyan - Amberiotis
- Joe Greco - Alfred Biggs
- Oliver Bradshaw - Mr Hendry
- Jean Ainslie - Alison Hendry
- Bruce Alexander - Albert Chapman
- Mary Healy - Beryl Chapman
- Tom Durham - Lionel Arnholt
- John Carlin - Dr Bennett
- George Waring - First Coroner
- John Warner - Second Coroner
- Ben Bazell - Sergeant Beddoes
- Dawn Keeler - Mrs Pinner
- Cassandra Holliday - Receptionist
- Stephen Bird - Pageboy
- John Peters - Sergeant
- Chris Spicer - 'Claudio'
- Alan Penn - 'Antonio'
- Guy Oliver-Watts - 'Benedick'
- David Bowles - Sgt. Evans (uncredited)
- Jill Goldston - Maid (uncredited)
- Cole Henderson - Driver (uncredited)
- Caroline Blakiston - Julia Carstairs
- Ruth Gemmell - Miss Sweetiman
- Elizabeth Berrington - Grace Springer
- Natasha Little - Ann Shapland
- Caroline Goodall - Lady Yardly
- Rosalind Bennett - Marie Marvelle
- Cathryn Harrison - Cecily, Lady Horbury
- Shaun Scott - Norman Gale
- David Firth - Lord Horbury
- Richard Ireson - Inspector Fournier
- Jenny Downham - Anne Giselle
- Eve Pearce - Madame Giselle
- Roger Heathcott - Daniel Clancy
- Guy Manning - Jean Dupont
- Gabrielle Lloyd - Elise
- John Bleasdale - Mitchell
- Harry Audley - Raymond Barraclough
- Yves Aubert - Airline Clerk
- George Rossi - Zeropoulos
- Nick Mercer - Policeman
- Hana Maria Pravda - Concierge
- Raymond Sawyer - Hotel Clerk
- Russell Richardson - French Registrar
- Joe Absolom - James Bentley
- Simon Molloy - District Judge
- Sarah Smart - Maude
- Raquel Cassidy - Maureen Summerhayes
- Emma Amos - Bessie Burch
- Billy Geraghty - Joe Burch
- Mary Stockley - Eve Carpenter
- Paul Rhys - Robin Upward
- Amanda Root - Mrs Rendell
- Agatha Christie
- Nick Elliott
- Brian Eastman
Daniel Lapaine interpreta a Tim Allerton en la serie.
James Fox interpreta a Colonel Race en la serie.
Alex Palmer hace el papel de Robert Grant.
Elliott Gould hace el papel de Rufus Van Aldin.
Sara Stewart interpreta a Jane Olivera en la serie.
Alan Howard interpreta a Benedict Farley / Hugo Cornworthy en la serie.
Jonathan Hackett interpreta a Claude Chantalier en la serie.
Vernon Dobtcheff interpreta a Simeon Lee en la serie.
Paul Freeman interpreta a Col. Carbury en la serie.
Alexander Siddig hace el papel de Shaitana.
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