- Amy Farrington - Susan
- Susan Gibney - Maggie Harris
- Elizabeth Ann Bennett - Jeannie
- Richie Keen - Stu Miller
- Paul David Stewart - Jimmy
- Susan Beaubian - Bonnie
- Molly Cheek - Diane Michaelson
- Suzanne Ford - Joyce
- Jeff Harlan - Earl
- Ken Lerner - Rick
- Ron Nicolosi - Man OS Voice
- Allan Wasserman - Roger
- Charles Rahi Chun - Attendant
- Jason Lansing - Matt
- Josh Ackerman - Co-Worker Sara Kisses
- Kyle Dunnigan - Kevin
- Rachelle Carson - Sharon Adelman
- Rachelle Carson - Cindy Miller
- Jaime Ray Newman - Amanda
- Wendy Worthington - Dog Lady
- Johnathan McClain - Steven
- Jeremy Kent Jackson - Randall
- Patrick Warburton - Bill Harris
- Cloris Leachman - Lois, Peter's Mother
- Rob Reinis - The Jer
- Jaime Pressly - Alex
- Travis Wester - Pat
- Miriam Flynn - Barb
- Danielle Schneider - Beth
- David Garrison - Gordon Miller
- Melissa Molinaro - Hostess
- Benjamin King - Don
- Bunny Summers - Gladys
- Romy Walthall - Mrs. Gardner
- David Weisenberg - Man
- Kathleen LaGue - Volvo Owner
- Andy Richter - Clerk
- Nick von Esmarch - Dr. Fishman
- Kate Walsh - Joanna
- John Ross Bowie - CocoNate
- Joseph R. Sicari - Bob
- Aixa Clemente - The Therapist
- Kevin Farley - Karl Pinski
- James Patrick Stuart - Roger
- Shawn Christian - Darren
- Jim Meskimen - Dr. Kassel
- Pamela Fryman
- David Guarascio
- Moses Port
John Larroquette hace el papel de Peter Brennan.
Christine Baranski hace el papel de Annie Brennan.
Jeff Bryan Davis hace el papel de Todd Brennan.
Melanie Paxson interpreta a Sara Brennan en la serie.
Tyler Francavilla hace el papel de Tim Brennan.
Susan Gibney interpreta a Maggie Harris en la serie.
Capítulo disponible en las siguientes plataformas:
