- Stephen Colbert - Alf Musik
- John Slattery - John Slattery
- Jimmy Fallon - Jimmy Fallon
- Talia Balsam - Talia Balsam
- Harry Slattery - Harry Slattery
- PJ Adzima - Emil
- Andrew R. Butler - Declan
- Gayle Samuels - Tammy
- Rao Rampilla - Pharmacist (uncredited)
- Carson Daly - Carson Daly (voice)
- Jayson Wesley - Producer
- Dillon Geyselaers - Sound Engineer
- Danny Doherty - Construction Worker #1
- Kenneth De Abrew - Rudi
- Nic Inglese - PA
- Brian Corrigan - Old Customer
- Randi Kaplan - Pedestrian
- Tina Fey - Dolly Parton
- Dean Winters - Nick
- Barzin Akhavan - Zahir
- Alix Elias - Mrs. Bellow
- Robin S. Walker - Bank Teller
- Howard W. Overshown - Detective #1
- Eric R. Williams - Bartender
- Jennifer Simard - Daphne
- Ryan Karels - Firewood Sommelier
- Henry Trueheart - Boybies Hottie
- Aaron Dalla Villa - Mesh Blazer Guy
- Peter Smith - Bartender
- Teddy Coluca - Rusty
- Adam Perry - Guy
- Cavan Rogers - Excited Guy 1
- Anthony Gusevich - Excited Guy 4
- Iván Amaro Bullón - Diner Patron (uncredited)
- Ken Holmes - Theater Audience / Fan / Y2Gay Attendee (uncredited)
- Andrew Rannells - Kev Hamlin
- Bowen Yang - Zander (uncredited)
- Bowen Yang - Zander
- Dave Hill - DJ Squeeb
- Ryan Steele - Boy Next Door
- Stephanie D'Abruzzo - Hermit Crab Puppeteer (uncredited)
- Ashley Park - Ashley Gold
- Vanessa Williams - Nance Trace
- Will Chase - Stet
- Jillian Hervey - Jillian Hervey (Lion Babe)
- Alex Lukmann - Ray
- Richard Haddad - Flex
- Alysha Umphress - Baby
- Lipica Shah - Producer
- Lisann Valentin - Jingle Ball Organizer
- Vin Craig - Another Guy
- Dan Chen - Sound Guy
- Andre De Leon - Patient
- Anthony R. Mottola - PA
- John-Deric Mitchell - Excited Fan Guy (uncredited)
- Jonathan Hadary - Larry Plumb
- Tim Meadows - Tim Meadows
- Heidi Gardner - Cara
- James Monroe Iglehart - Nathan Reasel
- Joey Sasso - Joey Sasso
- Mary Chieffo - June
- Crissa Jackson - Crissa Jackson
- Amy Sedaris - Kris
- Neil Flynn - Chris
- Amber Ruffin - T.K.
- Mario Cantone - Mario Cantone
- Kyle Selig - D'Blaze
- Daniel Breaker - Scott
- Erika Henningsen - Young Gloria
- Drew Scott - Drew Scott
- Jonathan Silver Scott - Jonathan Silver Scott
- Grey Henson - Tate
- Janine Brito - Caroline Bianca Diaz
- John Lutz - Percy
- Jeremiah Craft - Lil Stinker
- Jeremiah Craft - Bootsy Tings
- Chad L. Coleman - Sheawn
- Judy Gold - Dr. Madden
- Ellen Tamaki - Amanda
- Gabriel Lopez - Construction Worker #2
- Shyaporn Theerakulstit - Paparazzi
- Joy Suprano - Jackie Werth
- Stephen Carlile - Prince Andrew
- John James Cronin - Tyler
- Shari Albert - Meg
- Malachi Nimmons - Bar Manager
- Glo Tavarez - Schieffer Fan
- John Early - Chuck Dennis
- Paul Dinello - Randy
- Thomas Doherty - Gray Holland
- Mugga - Dr. Lisa Masch
- Erin Markey - Modor
- Regina Taufen - Waitress
- Teresa Lee - Excited Woman
- Adriane Lenox - Carmen Wiggens
- Ron Canada - Dana Wiggens
- Janine DiVita - Stacy
- Curran Connor - Boat Guy
- Catherine Cohen - Taffy England
- Ingrid Michaelson - Pixie
- Rebecca Lobo - Rebecca Lobo
- Thomas Kopache - Crandall
- Mario López - Mario López
- Kit Hoover - Kit Hoover
- Ryan Radis - Kir
- Howard Feller - Vent Guy
- Paul McCallion - Emcee
- Arianna Rosario - Parma Singing Fan
- Richard Kind - Richard Kind
- Lea DeLaria - Bev
- Mike Carlsen - Carl
- Pat Battle - Pat Battle
- John Bolton - Prince Charles
- Maceo Oliver - Aaron
- Steve Routman - Leonard Kravitz
- DazMann Still - Brad
- AJ Cedeno - New Brad
- Maya Deshmukh - New New Jess
- Nick Mestad - Goldman Guy
- Hoda Kotb - Hoda Kotb
- Nicole Shalhoub - Dr. Ji
- Valerie Sue Love - Ms. Mara
- Brian Ray Norris - Construction Worker
- Rick Crom - Strange Man
- Howie Schaal - Paparazzi
- Katherine Laheen - Abigail
- Woody Fu - Director
- Morgan Jay - J Swerve
- Brian Faherty - Eddie
- Alexis Suarez - Security Guard
- Elle Graper - Young Summer
- Wenne Alton Davis - Carpenter
- Kal Mansoor - Reporter
- Jamil Moore - Ryan Salge
- Sherrod Small - Paul
- Paul Juhn - Raymond
- Devin Bockrath - Drunk Lady
- Mahadeo Shivraj - Bodega Cashier
- Alex Hazen Floyd - Co-Z Boi
- Gibson Frazier - Dr. Cole
- Jann Ellis - Older Woman
- Nanie Méndez - Nurse
- Damian Muziani - Man on Street
- Jeremy Lawrence - Old Man
- Barton Cowperthwaite - Broyce
- Chris Chirdon - Blonde Husband
- Makia Martin - Lady
- Dash Perry - Brace
- Kristen Faith Oei - Dancer
- Christine Sienicki - Dancer
- Hayley Podschun - Dancer
- Sherisse Springer - Dancer
Sara Bareilles interpreta a Dawn en la serie.
Busy Philipps hace el papel de Summer.
Paula Pell hace el papel de Gloria.
Capítulo disponible en las siguientes plataformas:
