- Will Lyman - Self - Narrator (voice)
- Will Lyman - Self, Narrator
- Will Lyman - Narrator (voice)
- Andrey Zykov - Self - Former Police Investigator
- Gillian Findlay - Self - Correspondent
- Stanislav Belkovsky - Self - National Strategy Institute, Moscow
- Marina Salye - Self - Former Deputy of the Legislative Assembly of Leningrad
- Борис Ельцин - Self (archive footage)
- Mikhail Khodorkovsky - Self - Former CEO, Yukos Oil Company
- Jürgen Roth - Self - German investigative reporter
- Dmitry Medvedev - Self
- Mark Zuckerberg - Self (archive footage)
- Bill Clinton - Self (archive footage)
- Chelsea Clinton - Self (archive footage)
- Ivana Trump - Self (archive footage)
- Melania Trump - Self (archive footage)
- Donald Trump Jr. - Self (archive footage)
- Tiffany Trump - Self (archive footage)
- Eric Trump - Self (archive footage)
- Vanessa Trump - Self (archive footage)
- Barron Trump - Self (archive footage)
- Roger Stone - Self (archive footage)
- Roger Stone - Self
- Xi Jinping - Self (archive footage)
- Jared Kushner - Self (archive footage)
- Mike Pence - Self (archive footage)
- Newt Gingrich - Self
- John Podesta - Self
- Kamala Harris - Self (archive footage)
- John McCain - Self (archive footage)
- Nancy Pelosi - Self (archive footage)
- Chuck Schumer - Self (archive footage)
- Rudolph Giuliani - Self (archive footage)
- Brett Kavanaugh - Self (archive footage)
- Vladimir Putin - Self
- Hillary Clinton - Self (archive footage)
- Michelle Obama - Self (archive footage)
- George W. Bush - Self (archive footage)
- Barack Obama - Self (archive footage)
- Donald Trump - Self (archive footage)
- Jill Biden - Self (archive footage)
- Sasha Obama - Self (archive footage)
- Malia Ann - Self (archive footage)
- Barbara Bush - Self (archive footage)
- Laura Bush - Self (archive footage)
- Hunter Biden - Self (archive footage)
- Beau Biden - Self (archive footage)
- Steve Bannon - Self
- Rex Tillerson - Self (archive footage)
- Bernie Sanders - Self (archive footage)
- Rodrigo Duterte - Self
- Amal Clooney - Self
- Maria Ressa - Self
- Liz Day - Self (Reporter)
- Sophie Okonedo - Narrator
- Michael Flynn - Self
- Ben Rhodes - Self
- Dana Priest - Self
- Mark Rossini - Self
- Joe Biden - Self (archive footage)
- Joe Biden - Self
- Evan Osnos - Self
- Emma Sky - Self
- Eugene Robinson - Self
- Peter Baker - Self
- Lawrence Wilkerson - Self
- Colin Powell - Self
- Jane Mayer - Self
- Rajiv Chandrasekaran - Self
- Ahmed Rashid - Self
- L. Paul Bremer - Self
- Ali Soufan - Self
- Jelani Cobb - Self
- Ryan Crocker - Self
- Chuck Hagel - Self
- John R. Bolton - Self
- Susan Glasser - Self
- Trevor Howard - Narrator (voice)
- Neal Beidleman - Self
- David Breashears - Narrator
- Guy Potter - Self
- Charlotte Fox - Self
- Lene Gammelgaard - Self
- Makalu Gau - Self
- Sandy HIll - Self
- Lou Kasischke - Self
- Ngawang Syakya Sherpa - Self
- Pemba Norbu Sherpa - Self
- Tashi Tseri Sherpa - Self
- John Taske - Self
- Beck Weathers - Self
- Helen Wilton - Self
- Anatoli Boukreev - Self (archive footage)
- Scott Fisher - Self (archive footage)
- Clarence Thomas - Self (archive footage)
- Ginni Thomas - Self (archive footage)
- Kurt Andersen - Self
- Dick Armey - Self
- George H. W. Bush - Self (archive footage)
- Vanessa Fica - Self
- Anita Hill - Self (archive footage)
- Lester Johnson - Self
- Randall Kennedy, PhD - Self
- Robert F. Kennedy - Self (archive footage)
- Glenn Loury - Self
- Malcolm X - Self (archive footage)
- Ronald Reagan - Self (archive footage)
- Denver Riggleman - Self
- Phyllis Schlafly - Self (archive footage)
- Nina Totenberg - Self
- Angela Wright - Self
- Louie Gohmert - Self (archive footage)
- Rosa DeLauro - Self
- Pramila Jayapal - Self (archive footage)
- John Dingell - Self (archive footage)
- Marjorie Taylor Greene - Self (archive footage)
- Alan K. Simpson - Self
- Jeff Jamar - Self - FBI, Waco Commander
- Peter Breggin - Self - Psychiatrist
- John Halligan - Self - Parent of Ryan
- Ryan Halligan - Self (archive footage)
- Adel Al-Jubeir - Himself
- Prince Mohammed bin Salman al Saud - Himself
- Turki Al-Faisal - Himself
- Hala Al-Dosari - Herself
- Alia Al-Hathloul - Herself
- Jamal Khashoggi - Himself (archive footage)
- Saad Al-Faqih - Himself
- Vivek Ramaswamy - Self
- Michael Smerconish - Self (archive footage)
- Seth Meyers - Self (archive footage)
- Joy Reid - Self (archive footage)
- Megyn Kelly - Self
- David French - Self
- Tucker Carlson - Self (archive footage)
- Keith Ellison - Self
- Rona Barrett - Self (archive footage)
- Louise Sunshine - Self
- Mary Trump - Self
- Tony Schwartz - Self
- Marc Fisher - Self
- Gwenda Blair - Self
- Michael D'Antonio - Self
- Timothy L. O'Brien - Self
- Marie Brenner - Self
Sophie Okonedo interpreta a Narrator en la serie.
Will Lyman interpreta a Self - Narrator (voice) en la serie.
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