- Max Beesley - Anthony Henderson
- Katherine Kelly - Brooke
- Bradley Whitford - Calvin Cooper
- Emily Coates - Milly
- Tyler Luke Cunningham - James
- Aude des Pallieres - Sofi Adjani
- Tim Bentinck - Marcus
- Harki Bhambra - Stu
- Adam Loxley - Simon
- Clare Perkins - Shirelle
- Reece Ritchie - Rick
- John Askew - Darren Barron
- Sophia La Porta - Roxy Barron
- Ewan Bailey - Tony
- Philip Martin Brown - Terry
- Julie Legrand - Shell
- Sean Power - Bradley
- Jane Horrocks - Tanya Bert
- Giles Terera - William Pendelton
- Martha Plimpton - Clara
- George Bukhari - Leon
- Tom Cotcher - Trevor
- Caroline Guthrie - Linda
- Melissa Johns - Beth
- Sam Neill - Duncan Paulson
- Doon Mackichan - Victoria
- Nina Barker-Francis - Kaz
- Naomi Battrick - Maddy
- Cara Horgan - Camilla
- Adelle Leonce - Bessie
- Maggie Steed - Elizabeth
- Daniel Dae Kim - Gabriel Cole
- Saffron Coomber - Steph
- Dan Wheeler - Man in Bar
- Dan Wheeler - Man In Bar
- David Hargreaves - Warren
- Oliver Lansley - American Mike
- Jason Thorpe - Ross
- Paul Ready - Damien Paulson
- Kevin Bishop - Danny Davis
- Amar Chadha-Patel - Deepak
- Yasmine Akram - Ashley
- Keir Charles - George
- Dinita Gohil - Narinda
- Amy Beth Hayes - Cheryl
- Sukey Willis - Runner
- Christine Bottomley - Sally Henderson
- Fiona Button - Annie
- Manuel Pacific - Pedro
- Simon Bubb - Simon
- Ian Davies - Peter the Director
- Holli Dempsey - Carly
- Tsion Habte - Summer Bolton
- Andrea Hall - Nurse
- Chu Omambala - Edward Bolton
- Rebecca Scroggs - Abigail
- Rebecca Scroggs - Abigail Reese
- Indra Ové - Joan Bolton
- Rebecca Root - Allie Gregs
- Katharine Bennett-Fox - Cheryll
- Nicole Gibson - Koko
- Amy Huberman - Celina Pope
- Rose Johnson - Rose
- Dan Mersh - Policeman
- Dean Nolan - Man in the Beer Garden
- Steven Pacey - Robert Frost
- Darren Boyd - Jeremy
- Eliza Riley - Kelly
- Amanda Abbington - Alexa
- Cara Theobold - Caitlin
- Vikash Bhai - Mike
- Mark Dexter - Lewis
- Deirdre Mullins - Janet
- Sophie Robertson - Arabella
- Stephen Wight - Jamie
- Andrew Leung - Craig
- Kadiff Kirwan - Gary
- Lloyd Everitt - Patrick Andrews
- Andy Gillies - Paul the Doorman
- Julian Kostov - Juan
- Leander Vyvey - Deon
- Toby-Alexander Smith - Terry
- Robert Ryan - Right Wing Protester
Sam Neill interpreta a Duncan Paulson en la serie.
Anna Paquin hace el papel de Robyn.
Sophie Okonedo interpreta a Caroline en la serie.
Rufus Jones interpreta a Mark en la serie.
Rebecca Benson interpreta a Melody en la serie.
Lydia Wilson interpreta a Eve en la serie.
Genevieve Angelson interpreta a Ruth en la serie.
Meghan Treadway hace el papel de Belle.
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