- Lew Ayres - Oliver Hawthorne
- Kay Lenz - Ellen Ross
- Leslie Nielsen - Matthew Vail
- Jan Smithers - Barbara Hensen
- Heather O'Rourke - Jillian Marsh
- Peter Scolari - Ted Caton
- Jack Coleman - Eric Jordan
- Larry Jenkins - Lyman Whittaker
- Melissa Sue Anderson - Nikki Gatos
- Michael Constantine - Mr. Harding
- Steve Forrest - James Osborne
- Hope Lange - Catherine Smith
- Monte Markham - Galen Smith
- William R. Moses - Peter Harding
- Vic Tayback - Thomas Velasco
- Marcia Wallace - Friend at Surprise Party
- Peter Ashton - Sir John
- Rance Howard - Hank
- Christian Jacobs - Scott Hargrove
- Theresa Hayes - Lisa
- Rod Loomis - Bob
- Parley Baer - Minister
- Nigel Bullard - Steve
- Elizabeth Coulter - Vanessa
- Carey Hayes - Lifeguard
- Casper Roos - Casper
- Morgan Lofting - Osborne's Secretary
- Kathleen O'Malley - Ada
- Scooby Vincent - Ellie
- Mary Crosby - Blythe Stewart
- Michael Goodwin - Ben Allison
- John James - Michael Bretton
- Dean Jones - Steve Marsh
- Michelle Phillips - Alicia Marsh
- Patricia Smith - Miss Roberts
- Eve Brent - Parrish Housekeeper
- Anne Marie McEvoy - Marcie
- Pamela Bellwood - Susan Blaine
- Ben Murphy - David Carson
- Christopher Norris - Elisa Crawford / Eden Crawford
- Cristina Raines - Beth Farley
- Bill Dearth - Luke
- Pat Destro - Mrs. Small
- Margaret Howell - Pat
- Danny Nash - Tommy
- Justin Gocke - Jason
- Karen Carlson - Lorna Hodges
- Kim Lankford - Jeanine Prescott
- Leigh McCloskey - Travis Burke
- Dick Sargent - Dennis Hodges
- John Saxon - Zach Donahue
- David Wayne - Professor Wheeler
- Jason Presson - Jonathan Hodges
- Paul Eiding - Stanley
- Rigg Kennedy - Dr. Epner
- Joel Kramer - Trucker #1
- Buddy Farmer - Trucker #2
- Lyla Graham - Dr. Dunsmuir
- Colleen Dewhurst - Rachel Green
- Harold Gould - Morris Mindakovitch
- Richard Hatch - Robert Westphal
- Ed Nelson - Bill Garnett
- Donna Pescow - Anne Sherman
- Virginia Hawkins - Mrs. Adams
- Toni Sawyer - Mrs. Westphal
- Byron Morrow - Mr. Westphal
- Peter De Anda - Clegg
- Ed Ruffalo - Partner
- Kenneth C. Wilson - Driver
- Esther Rolle - Nellie
- Connie Sellecca - Sara Hawthorne Nevins
- Joe E. Tata - Nick
- Eric Lawson - Auggie
- Amzie Strickland - Mrs. Hawthorne
- Jayson Kane - Manager
- Diana Bellamy - Concessionaire
- Alan Feinstein - Nick Hardy
- Melanie Mayron - Michelle Peters
- Joanna Pettet - Claire Hardy
- Dick Van Patten - Alan Nettles
- Edward Winter - Edward Dreighton
- Sandy Freeman - Mrs. Mason
- Sandy Freeman - Diane
- Kathleen Hughes - Secretary
- Buddy Ebsen - Walter Lewis
- Charles Frank - Johnny Bowers
- Alan Fudge - Tom Warren
- Mackenzie Astin - Jeremy Warren
- Renne Jarrett - Janet Warren
- Kathryn Reynolds - Elinor Sweeney
- Dean Stewart - Man
- Karl Held - Henry
- John Beck - Ray Powell
- Joyce DeWitt - Lynn Powell
- Lee Meriwether - Julia Bennett Parsons
- Michael Nader - Kent Halliday
- Molly Cheek - Margaret Keller
- Barret Oliver - Matthew Powell
- Grant Goodeve - Stuart Scranton
- Eleanor Parker - Nora Spencer
- Barbara Rush - Marion Owens Norris
- Wendy Smith Howard - Wendy Owens
- Leigh Lombardi - Hilary Ashton
- Vaughn Armstrong - Andrew
- Dee Croxton - Grace
- Mel Ferrer - George Matthews
- Florence Henderson - Lyla Armstrong
- Bo Hopkins - William Davis / Drew Gilbert
- Carol Lynley - Karen Davis
- Cassie Yates - Monique Gilbert
- Don Marshall - Jim Blair
- Eugene Peterson - John Hutchins
- Edmund Balin - Herb
- Scotty Sachs - Cab Driver
- Susan Blakely - Jennifer Avery
- Macdonald Carey - Norman Prentice
- Michael Gross - Tom Lindsay
- James Houghton - Nicholas Simmonds
- Morgan Stevens - Dean Ryan
- James Luisi - Jordan Hollis
- Richard Bull - Roger Dillon
- Ivan Bonar - Dr. Elliot
- Charles Robinson - Salesman
- Fred Lerner - Conventioneer
- Clare Torao - Photographer
- Leah Ayres - Stacey Barnes
- Tom Bosley - Malcolm Beck
- Paul Burke - Richard Foster
- Vera Miles - Joanna Shaw
- DeAnna Robbins - Robin
- Charles Lucia - Jack Parrish
- Tracey Ross - Secretary
- Arthur Taxier - Valet
- Heidi Bohay - Cindy Murdock / Sheena Fontaine
- Kevin Brophy - Robbie Wayne
- Samantha Eggar - Megan Brody
- Gary Lockwood - Stan Gallagher
- Hank Brandt - Mr. Murdock
- Penelope Windust - Mrs. Murdock
- Kate Charleson - Courtney Perkins
- Caren Kaye - Kathy Cullen
- Lois Nettleton - Helen Sanderson
- Robert Reed - Tim Sanderson
- Ted Shackelford - Mark Stafford
- Jenny Beck - Sharon Mason
- Shea Farrell - Phillip Lawton
- Paula Kelly - Alice Taylor-Hancock
- Mary Kate McGeehan - Molly Thatcher
- Stacey Nelkin - Donna Sinclair
- Philip Levien - Tom Harris
- Claudette Wells - Jan
- Terry Cook - Secretary
- Ron Ray - Minister
- Cathy Lee Crosby - Linda Hudson / Lynette Beaumont
- Phyllis Davis - Beth Reynolds
- Robert Fuller - Mike Dayton
- Jared Martin - Evan Selman
- Tony Roberts - Thad Holcolmbe
- Annette Sinclair - Vicky Selman
- Robert Miano - Mechanic
- Christine Belford - Patricia Carver
- Robert Goulet - Gabe McGuire
- David Groh - Brad Evans
- David Hedison - Neil Palmer
- Lance Kerwin - Adam Hill
- Fred Holliday - Russ
- Timothy Blake - Vera
- Ellen Bry - Amanda Tyler
- Dee Wallace - Gail Aames
- Gordon Thomson - Jim Chasen
- Efrem Zimbalist Jr. - Alex Hale
- Bruce Fairbairn - Steve Bates
- Lew Saunders - Policeman
- Vincent Baggetta - Richard Douglas
- Beverly Garland - Lucy Rowens
- Kevin McCarthy - Ben Harper
- Randolph Powell - Gordon Harper
- Lauren Tewes - Dorothy Keating
- Patricia Barry - Elaine Mailand
- Robert Clarke - Minister
- Beau Starr - Lloyd Hundley
- John Karlen - Arthur Barwell
- Belinda Montgomery - Lisa Hennessey
- Michael Spound - Ken Grant
- Michael Hennessy - Craig Radford
- Paul Petersen - Policeman
- Cis Rundle - Receptionist
- Barry Sattels - Howard Cooper
- Michael Gregory - Bob Grayland
- Pat Crowley - Maggie Singer
- Rosemary Forsyth - Mrs. Bennetts
- Diane Franklin - Emily Bennetts
- Ken Olandt - Jake Turner
- Joan Prather - Robin Sloan
- Stuart Whitman - Ned Gilbert
- Beverly Brown - Harriet
- Anne Francis - Ruth Cunningham
- Fredric Lehne - Dan Matthews
- Jeremy Licht - Joey
- Peter Mark Richman - Frank Cunningham
- Wendy Schaal - Emma Tate
- Robin Strand - Kevin Curtis
- Claudia Cron - Monica
- Ed Kenney - Chauffeur
- J. Víctor López - Gardener
- Jeanette Miller - Woman
- Aaron Speiser - Director
- Lindsay Price - Lan
- Douglas S. Cramer
- Aaron Spelling
Hope Lange interpreta a Catherine Smith en la serie.
Buddy Ebsen interpreta a Walter Lewis en la serie.
Mel Ferrer hace el papel de George Matthews.
Lew Ayres hace el papel de Oliver Hawthorne.
Gary Lockwood hace el papel de Stan Gallagher.
Anthony Franciosa hace el papel de Cary Maxwell.
Deborah Adair interpreta a Daisy Lloyd en la serie.
Anne Jeffreys interpreta a Rita Hargrove en la serie.
Richard Kantor hace el papel de Brian Fletcher.
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