- Sunita Mani - Nancy
- Paul Dano - Jeff
- Marc Petrosino - Melf
- Steve Buscemi - Q
- Bobbi Salvör Menuez - X
- Macy Rodman - Pop News Reporter
- Evan Mock - Z
- Nick Naney - O
- Reza Nader - MC
- Bardia Salimi - Amina's Partner
- Amy Zimmer - Oyster Seller
- J.B. Adams - Board Member
- Getchie Argetsinger - Crayola Representative in Yellow
- Meng Ai - Crayola Board Member
- River L. Ramirez - Toast
- Bowen Yang - Dodo
- Sandra Caldwell - Lawyer
- Alexa Demie - Becca
- Ziwe Fumudoh - Airline's attendant
- Jaboukie Young-White - Skyler
- Greta Titelman - Gina
- Dominique Jackson - Algorithm
- Matt Barats - Waiter
- Maddie Corman - 90 second Clinic Doctor
- Tómas Matos - Chester
- May Hong - Alex
- May Hong - Bartender
- Aidy Bryant - Denise
- Rick Crom - Lawyer
- John Early - Chips/Figero
- Aaron Jackson - Coco (voice)
- Geo Lee - Man
- Eudora Peterson - Amina Roberts
- Josh Sharp - Coco (voice)
- Julia Fox - Mrs. Claus
- Jenni Ruiza - Toilet Seat Dress Customer
- Kim Petras - Mermaid
- Tilda Swinton - Water (voice)
- Kate Berlant - Theme Park Madame Victorious
- Spike Einbinder - Carl
- José Gamo - Madame Victorious Fan
- Bernardo Velasco - Edwin
- Michael Graceffa - Derrrick
- Angel Yau - Tara
- David Neal Levin - RIchard
- Genii - Bus Stop Patron
- Sydnee Washington - Vicky
- Ikechukwu Ufomadu - Oscar
- Princess Nokia - Mermaid
- Princess Nokia - Telemarketing Mermaid #2
- Amy Sedaris - Vanesja's Former Acting Coach
- Natasha Lyonne - Susanna
- Dylan O'Brien - Dustin
- Boy Radio - Aurelio
- Juanes Montoya - Diego
- James Scully - Dog (voice)
- James Scully - Brandon
- Ana Fabrega - Trish
- Jordan Mendoza - Luis
- Max Wittert - Jason
- Tommy Dorfman - Commercial Director
- Erin Markey - Acting Coach
- Sandy Honig - Dr. Sarah
- Emma Stone - Genevieve
- Rachel Dratch - Rellany
- Rosie Perez - Bianca
- Cole Escola - Dina
- Richard Perez - Donnie
- Sam Taggart - Bryce
- Patti Harrison - Fish
- Francesca D'Uva - Zappo Secretary
- Ali Herting
- Alex Bach
- Emma Stone
- Dave McCary
- Daniel Powell
- Olivia Gerke
Martine Gutierrez interpreta a Vanesja en la serie.
Tómas Matos hace el papel de Chester.
Joe Rumrill interpreta a Bibo (voice) en la serie.
Capítulo disponible en las siguientes plataformas:
