- Frank Welker - Fred Jones / Scooby-Doo (voice)
- Frank Welker - Lulu (voice)
- Grey DeLisle - Daphne Blake (voice)
- Grey DeLisle - Lady Queen / Additional Voices (voice)
- Grey DeLisle - Nurse (voice)
- Mark Hamill - General Stall (voice)
- Chord Overstreet - Mitchell / Andrew (voice)
- JB Blanc - Vic / Colander (voice)
- Ben Diskin - Additional Voices (voice)
- David Kaye - Bradwick / Headless Count (voice)
- Julie Nathanson - Kimmy / Bride’s Mother (voice)
- Laraine Newman - Professor Salazar / Running Girl / Female Security Guard (voice)
- Dee Bradley Baker - Professor / Sobek / Duncan (voice)
- Kiff Scholl - Jeff / Male Security Guard (voice)
- Edward Bosco - Werewolf (voice)
- Christian Lanz - Miguel (voice)
- Candi Milo - Ms. Tuckle (voice)
- Phil Morris - Dunsbury (voice)
- Liliana Mumy - Daughter (voice)
- Ken Spears
- Joe Ruby
- Sam Register
Mark Hamill interpreta a General Stall (voice) en la serie.
Matthew Lillard interpreta a Shaggy Rogers (voice) en la serie.
Grey DeLisle interpreta a Daphne Blake (voice) en la serie.
Kate Micucci interpreta a Velma Dinkley (voice) en la serie.
Frank Welker interpreta a Fred Jones / Scooby-Doo (voice) en la serie.
Capítulo disponible en las siguientes plataformas:
