- Joss Fong - Narrator (voice)
- Maria Bello - Narrator (voice)
- Christian Slater - Narrator (voice)
- Estelle Caswell - Narrator (voice)
- LeVar Burton - Narrator (voice)
- Nick Kroll - Narrator (voice)
- Aasif Mandvi - Narrator (voice)
- Kevin Smith - Narrator (voice)
- Coleman Lowndes - Narrator (voice)
- Yara Shahidi - Narrator (voice)
- Kristen Bell - Narrator (voice)
- Rachel Bloom - Narrator (voice)
- Jerry Springer - Narrator (voice)
- Rachel McAdams - Narrator (voice)
- Kyle MacLachlan - Narrator (voice)
- Carly Rae Jepsen - Narrator (voice)
- ??? - Self
- ?? - Self (archive footage)
- ?? - Self (archive footage)
- ? - Self (archive footage)
- ? - Self (archive footage)
- RM - Self (archive footage)
- ?? - Self (archive footage)
- ??? - Self (archive footage)
- ??? - Self (archive footage)
- ??? - Self (archive footage)
- ?? - Self
- Mithra Jin - Self
- ??? - Self (archive footage)
- ??? - Self (archive footage)
- Psy - Self (archive footage)
- Hillary Clinton - Self
- Valentine Rugwabiza - Self
- Elizabeth Warren - Self (archive footage)
- Kirsten Gillibrand - Self (archive footage)
- Sandra Day O'Connor - Self (archive footage)
- Anderson Cooper - Self (archive footage)
- Hilary Swank - Narrator (voice)
- Maggie Siff - Narrator (voice)
- Abigail Disney - Self
- Michael Jordan - Self (archive footage)
- Mark Cuban - Self
- LaKeith Stanfield - Narrator (voice)
- J.K. Simmons - Narrator (voice)
- Bill Gates - Self
- Vincent Kartheiser - Narrator (voice)
- Natasha Lyonne - Narrator (voice)
- Cleo Abram - Narrator (voice)
- Andrew Carnegie - Self (archive footage)
- Warren Buffett - Self (archive footage)
- John D. Rockefeller - Self (archive footage)
- Cornelius Vanderbilt - Self (archive footage)
- John Maynard Keynes - Self (archive footage)
- Mehrsa Baradaran - Self - Author
- Cory Booker - Self - U.S. Senator
- Thomas Shapiro - Self - Sociologist
- Beth Jacobson - Self - Foreclosure Specialist
- James Baldwin - Self (archive footage)
- Edward A. Bouchet - Self - First Black Ph.D Recipient (archive footage)
- Shirley Chisholm - Self (archive footage)
- Bill Clinton - Self (archive footage)
- Ta-Nehisi Coates - Self (archive footage)
- Stephen Colbert - Self (archive footage)
- Bessie Coleman - Self - First Black Licensed Pilot (archive footage)
- Alan Greenspan - Self (archive footage)
- Jesse Jackson - Self (archive footage)
- Robert L. Johnson - Self - First Black Billionaire (archive footage)
- Martin Luther King Jr. - Self (archive footage)
- Dennis Kucinich - Self (archive footage)
- Abraham Lincoln - Self (archive footage)
- Alain Leroy Locke - Self - First Black Rhodes Scholar (archive footage)
- Malcolm X - Self (archive footage)
- Thurgood Marshall - Self - First Black Supreme Court Justice (archive footage)
- Hattie McDaniel - Self - First Black Oscar Winner (archive footage)
- Michelle Obama - Self - First Black First Lady (archive footage)
- Jesse Owens - Self - Four-Time Olympic Gold Medalist (archive footage)
- Colin Powell - Self - First Black Secretary of State (archive footage)
- Joseph Rainey - Self - First Black Congressperson (archive footage)
- Hiram Revels - Self - First Black Senator (archive footage)
- Jackie Robinson - Self - First Black MLB Player (archive footage)
- Franklin D. Roosevelt - Self (archive footage)
- Rick Santelli - Self (archive footage)
- William Tecumseh Sherman - Self (archive footage)
- Ruth Simmons - Self - First Black Ivy League President (archive footage)
- Edwin M. Stanton - Self (archive footage)
- George Stephanopoulos - Self (archive footage)
- Brian Williams - Self (archive footage)
- Neville Sanjana - Self - Biologist
- Jennifer Doudna - Self - CRISPR Pioneer
- John Evans - Self - Sociologist
- Hank Greely - Self - Law Professor
- Rebecca Cokley - Self - Disability Rights Activist
- Emmanuelle Charpentier - Self (archive footage)
- Francis Collins - Self (archive footage)
- Dick Costolo - Self (archive footage)
- Don Lemon - Self (archive footage)
- Keith Morrison - Self (archive footage)
- Reena Ninan - Self (archive footage)
- Bernie Sanders - Self
- John Franklin Stephens - Self (archive footage)
- Keri Russell - Narrator (voice)
- John Waters - Narrator (voice)
- Karlie Kloss Kushner - Narrator (voice)
- Aya Cash - Narrator (voice)
- Adolf Eichmann - Self (archive footage)
- Big Boi - Self (archive footage)
- Jane Fonda - Self (archive footage)
- Noam Chomsky - Self (archive footage)
- Mike Wallace - Self (archive footage)
- Jay-Z - Self (voice)
- Jay-Z - Self (archive footage)
- Rosario Dawson - Narrator (voice)
- Samira Wiley - Narrator (voice)
- Fidel Castro - Self (archive footage)
- George H. W. Bush - Self (archive footage)
- George W. Bush - Self (archive footage)
- Adolf Hitler - Self (archive footage)
- Donald Trump - Self (archive footage)
- Ronald Reagan - Self (archive footage)
- Nelson Mandela - Self (archive footage)
- Barack Obama - Self (archive footage)
- Richard Nixon - Self (archive footage)
- Ann Coulter - Self (archive footage)
- Peter Jennings - Self (archive footage)
- Dan Rather - Self (archive footage)
- Tom Brokaw - Self (archive footage)
- Ethan Hawke - Narrator (voice)
- Boris Johnson - Self (archive footage)
- Lyndon B. Johnson - Self (archive footage)
- Jake Gyllenhaal - Narrator (voice)
- Rainn Wilson - Narrator (voice)
- Sophie Okonedo - Narrator (voice)
- Keke Palmer - Narrator (voice)
- Hector Elizondo - Narrator (voice)
- Kim Cattrall - Narrator (voice)
- Kelly Rowland - Narrator (voice)
- Joseph Gordon-Levitt - Narrator (voice)
- Connie Britton - Narrator (voice)
- Ruth Negga - Narrator (voice)
- Doja Cat - Self (archive footage)
- ??? - Self (archive footage)
- Vladimir Putin - Self (archive footage)
- Xi Jinping - Self (archive footage)
- Joe Biden - Self (archive footage)
- Justin Trudeau - Self (archive footage)
- Ted Cruz - Self (archive footage)
- Michael Bloomberg - Self (archive footage)
- ??? - Self (archive footage)
- ????? - Self
- Jim Jones - Self (archive footage)
- Catherine Oxenberg - Self - Mother of NXIVM Cult Member
- Mark Zuckerberg - Self (archive footage)
- Muhammad Ali - Self (archive footage)
- Doug E. Fresh - Self (archive footage)
- Gigi Hadid - Self (archive footage)
- Leo J. Ryan - Self (archive footage)
- Jackie Speier - Self
- Emily Kassie
- Cleo Abram
- Ezra Klein
- Joe Posner
- Claire Gordon
Cleo Abram interpreta a Narrator (voice) en la serie.
Joss Fong interpreta a Narrator (voice) en la serie.
Maria Bello interpreta a Narrator (voice) en la serie.
Christian Slater interpreta a Narrator (voice) en la serie.
Estelle Caswell interpreta a Narrator (voice) en la serie.
LeVar Burton interpreta a Narrator (voice) en la serie.
Nick Kroll hace el papel de Narrator (voice).
Aasif Mandvi interpreta a Narrator (voice) en la serie.
Coleman Lowndes interpreta a Narrator (voice) en la serie.
Yara Shahidi hace el papel de Narrator (voice).
Capítulo disponible en las siguientes plataformas:
