- Norman Eshley - Detective Caufield
- Norman Eshley - Det. George Caufield
- Kathryn Leigh Scott - Gayle
- Laurence Luckinbill - Bruno Walters
- Susan Penhaligon - Emma Bartlett
- Grégoire Aslan - Scorbesi
- Elsa Martinelli - Renata Lucci
- Paul Maxwell - Buzz Wepner
- Linda Thorson - Diamond
- Laurence Naismith - General Platt
- Jenny Hanley - Sandi
- Rupert Graves - Prefect
- Murray Head - Pierre
- Weston Gavin - Mike
- David Garth - French Ambassador
- Carole André - Claudia
- Helmut Berger - Vidal
- Britt Ekland - Laura
- Judy Geeson - Selma Morell
- Olga Karlatos - Vlora
- Maurice Roëves - Willcox
- Mona Bruce - Dame Edith
- Marino Masé - Major Quirko
- Venantino Venantini - Xexo
- Richard Wyler - Algemon
- Moray Watson - Buckingham
- Carlos de Carvalho - Noli
- Luciano Bartoli - Shehu
- Joss Ackland - Gunther
- Moira Redmond - Livia Moreno
- Sharon Maughan - Carmela
- John Bennett - Colonel Ramon Perrez
- John Bailey - di Vallesi
- Stanley Lebor - Dalby
- Roy Evans - Dillon
- Juliette James - Margareta di Vallesi
- Zienia Merton - Mila
- Olga Lowe - Concierge
- Eve Karpf - Desk Clerk
- Raul Newney - Young Policeman
- Jorge Bosso - Plump Policeman
- Maurice Colbourne - Jed Blacket
- Cathryn Harrison - Sally
- Enzo Fiermonte - Guido
- Armando Bandini - Luigi
- Prunella Gee - Leila Sabin
- Emily Bolton - Yasmina
- Garrick Hagon - Abdul Hakim
- Stephen Greif - Masrouf
- Martin Benson - Elim
- Amos Mokadi - Col. Leon Garvi
- Geoffrey Greenhill - Yakovitz
- Aubrey Morris - Garton
- Nadim Sawalha - Rahaman
- Shango Baku - Caliban
- Reuben Elvy - Stern
- Ron Tarr - The Gorilla
- Maurice Denham - Prince Lorenzo
- Katia Christine - Sophia Castracane
- Tony Calvin - Vincenzo
- Clelia Matania - Francesca Manelli
- Giancarlo Prete - Boldini
- Laura De Marchi - Dolores
- Loris Bazzocchi - Guzzi
- Cyrus Elias - Moreno
- Alba Maiolini - Signora Streso
- Gianni Baghino - Mario
- Marilù Prati - Boys Mother
- Giovanni Cianfriglia - Henchman
- Kate O'Mara - Jeanette
- Bryan Marshall - O'Hara
- Carolle Rousseau - Colonel Dibha
- Burt Kwouk - Chula
- Neil Stacy - Randolf-Smith
- Norman Bird - Morgan
- Trevor Thomas - Cornelius
- Eamonn Boyce - Wilkes
- Timothy Morand - Francois
- Jack McKenzie - Marek
- Ric Young - Surinit
- Anthony Chinn - Kuon
- Clifford Earl - Plainclothes Policeman
- Ian Hendry - Roy Gates
- Annette Andre - Sandy
- Matthew Ryan - Mike
- Gerald Flood - Cleaver
- Tony Vogel - Diskett
- Tony Steedman - Brig. Danvers
- John Rolfe - Doland
- Maggie Wright - Cleaver's PA
- Reginald Jessup - Headmaster
- Charles Pemberton - Security Man
- Jonathan Burn - Dominic
- Kim Fortune - Robbie
- Christopher Timothy - The Gent
- Zuleika Robson - The Gent's Wife
- Patrick Jordan - Insp. Sullivan
- Gary Waldhorn - Rickman
- Mike Savage - Falkner
- Paul Gregory - Businessman
- Anton Phillips - Doctor
- Carolyn Seymour - Lady Greer Stevens
- Sarah Douglas - Sheila Northcott
- Michael Medwin - Guy Northcott
- Donald Pickering - Sir Trevor Stevens
- Ian McCulloch - Inspector Stone
- Vikki Richards - Nina
- Gregory Munroe - Otis
- Jane Hayden - Aileen
- Peter Burton - Dr. Evans
- Reg Lye - Lou
- David Healy - Hansen
- Brian Pettifer - Bartender
- Edmund Pegge - Police Officer
- Sandra Dickinson - Girl at Airport
- George Cole - Fred
- Anouska Hempel - Lynn Jackson
- Donald Houston - Commander Denning
- Frank Gatliff - Loader
- Gordon Gostelow - Parkinson
- Ian Collier - Army Captain
- Peter Quince - Bomb Sqd. Officer
- Edward Lyon - Police Officer
- Ray Callaghan - Hotel Clerk
- Catherine Schell - Samantha
- Anthony Steel - Max Boothroyd
- Bill Simpson - Professor Edmund Bartlett
- Peter Childs - Cartwright
- John Moreno - Pierre
- Richard LeParmentier - Demmell
- Godfrey James - Inspector Lebeau
- Gérard Camp - Professor
- John Kidd - Professor
- Ciaran Madden - Janie Lennox
- Frederick Jaeger - Inspector Grant
- Ian Cullen - Sergeant Taylor
- Brian Glover - Sam Plackett
- Heather Wright - Sally
- Royston Tickner - Billy Brayshaw
- George Sweeney - Tad
- Ralph Arliss - Malc
- Kim Hardy - Pam Plackett
- Sabina Franklyn - Linda
- Michael Segal - Train Guard
- Graham Ashley - Policeman
- Renu Setna - Shopkeeper
- Daniele Vargas - Capo
- Kim Goody - Michelle
- Piero Gerlini - Inspector Petrucci
- Piercorrado Dugoni - Abelardo
- Massimo Sarchielli - Marcello
- Alina De Simone - Signora Marcello
- Vito Domenighini - Paolo
- Selan Karay - Enrico
- Andrea Smith - Nurse
- Franco Beltramme - Capo's Man
- Giuliano Persico - Reporter
- Gustavo Nasti - Reporter
- John Woodvine - Ray Dennis
- Alfie Bass - Sammy
- Fiona Curzon - Jenny
- Stanley Meadows - Inspector Ashton
- Sally Lahee - Mrs. Stewart
- Sam Kydd - Charlie Stewart
- Alan Browning - Henry
- Neil Hallett - Andrew
- Paddy Joyce - Shill
- Jackie Pallo Jr. - Terry
- Terry Duggan - Rex
- Jacki Piper - Sally
- Thick Wilson - American Tourist
- Johnnie Wade - 3 Card Dealer
- Anton Rodgers - Geoffrey Connaught
- Mary Tamm - Gerri Hanson
- Diane Keen - Christine Hanson
- Geoffrey Keen - Sir Charles Meadley
- Bob Sherman - Jimmy
- Esmond Knight - Paul Hanson
- Neil McCarthy - Bradley
- Lesley Daine - Maureen
- Stephan Chase - Forbes
- Rosemarie Dunham - Prison Governor
- Milton Cadman - Prison Guard
- Cheryl Gilham - Girl in Negligee
- Chris Dillinger - Man
- Gayle Hunnicutt - Annabelle
- Stratford Johns - George Duchamp
- John Hallam - Bernadotti
- Leon Lissek - Pancho
- Edward Brayshaw - Oscar West
- Michael Robbins - Beeky
- Derren Nesbitt - Lebec
- Derren Nesbitt - Inspector Lebec
- Prentis Hancock - Vic
- Joe Lynch - Captain Finnigan
- Joe Lynch - Finnigan
- Wensley Pithey - Franklyn
- Michelle Newell - Genevieve
- Peggy Thorpe-Bates - Mrs. Cloonan
- Cyril Luckham - Coroner
- David English - Salesman
- Peter Brace - Crewman
- Rula Lenska - Diana Lang
- John Nolan - Corvis
- Lorraine De Selle - Maria
- Barry Andrews - Harland
- Struan Rodger - Erhard
- Nikki Gentile - Karen
- Don Powell - Lomax
- Marne Maitland - Kemal
- Roger Browne - Hendricks
- Gigi Reder - Valerio
- Roberto Messina - Mario
- Sergio Doria - Brown
- Marco Stefanelli - Pietro
- Franco Moruzzi - Carlo
- Karin Skarreso - Receptionist
- Mario Novelli - Gunman
- Donald Tesdahl - Journalist
- Jack Hedley - Colonel Dyson
- Thomas Baptiste - President Obono
- Paul J. Medford - Joey
- Derek Newark - Wright
- Marjie Lawrence - Rose
- Willie Jonah - Assassin
- Oscar James - Mombasa
- Jason Rose - Publican
- Jerome Willis - Inspector Thornton
- Emrys Leyshon - Records Officer
- John Barrett - Reiter
- John Atkinson - Jim Batley
- Robert Gillespie - Fred Batley
- Tessa Wyatt - Anna
- Gianrico Tondinelli - Antonio Farga
- Mel Ferrer - Dr. Paolo Brogli
- Luciano Pigozzi - Rotti
- Brizio Montinaro - Benito
- Guido Mannari - Franco
- Stelio Candelli - Capt. Genarro
- Massimiliano Baratta - Roberto
- Silvio Laurenzi - Fabio
- Dante Fioretti - Padrone
- Sam Wanamaker - Domenico
- Barbara Pilavin - Lucia
- Shane Rimmer - Falco
- Greta Vayan - Inga
- Bill Vanders - Captain
- Paolo Malco - Assassin
- Fortunato Arena - Peasant
- Andrea Occhipinti - Leo
- Antonio Cascio - Bodyguard
- Stefano Galantucci - Steward
- Geoffrey Copleston - Night Club Manager
- Stuart Wilson - Manfred
- Carla Romanelli - Lea Bartoni
- James Aubrey - Ingo
- Rodolfo Bigotti - Paolo
- Nicole Stoliaroff - Gaby
- Gaetano Russo - Karl
- Giacomo Rossi Stuart - Scheffer
- Licia Dotti - Giselle
- Elio Marconato - Mario
- Antonio Prester - Pietro
- Tamara Triffez - Helga
- Lynn Dalby - Marie de la Garde
- Karl Held - Shriber
- Artro Morris - Louis
- Jean Driant - Hotel Porter
- Graeme Eton - Desk Clerk
- Stacy Davies - Customs Officer
- Stanley McGeagh - Customs Officer
- Sam Wanamaker
- Cyril Frankel
- Roy Ward Baker
- Kevin Connor
- Tom Clegg
- Peter Medak
- Tony Williamson
- Michael Pertwee
- John Kruse
- John Goldsmith
- Moris Farhi
- Leon Griffiths
Laurence Luckinbill interpreta a Bruno Walters en la serie.
Neil McCarthy interpreta a Bradley en la serie.
Maurice Roëves hace el papel de Willcox.
Nadim Sawalha interpreta a Rahaman en la serie.
Mel Ferrer interpreta a Dr. Paolo Brogli en la serie.
Aubrey Morris hace el papel de Garton.
Paul Maxwell interpreta a Buzz Wepner en la serie.
Ian Ogilvy interpreta a Simon Templar en la serie.
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