- Randee Heller - Grammy
- Richard Biggs - FBI Man
- AnnaSophia Robb - Liza
- Emma Roberts - Addie Singer
- Erin Chambers - Kathy
- Erik Estrada - Police Officer
- Josh Server - Jeff Carlson
- Skyler Samuels - Ashley Blake
- Jerry Lacy - Mr. Hayfer
- Josie Loren - Maria
- Taran Killam - Trevor
- Matthew Gumley - Josh Nichols - Age 8
- Ian Paul Cassidy - Miles
- Emme Rylan - Allie
- Kimmy Robertson - Mrs. Galloway
- Julie Gonzalo - Tiffany Margolis
- Shawn Pyfrom - Michael
- Roark Critchlow - Dr. Glazer
- Leah Pipes - Mandi The Cheerleader
- Gary Coleman - Gary Coleman
- Jessy Schram - Larissa
- Vanessa Hudgens - Rebecca
- Dylan Minnette - Jeffrey
- Danica Stewart - Fan
- Jeremy Kent Jackson - Guitar Salesman Dude
- Anastasia Baranova - Yooka
- Brandon Quinn - Mark
- Samantha Hanratty - British Orphan
- Joey Mendicino - Buck
- Alyson Stoner - Wendy
- Molly Orr - Rina
- Wyatt Smith - Aiden
- Aaron Hill - Witherspoon
- Hunter Allan - Drake Parker - Age 8
- Beau Wirick - Tank
- Stacie Chan - Marta
- Johnny Lewis - Scottie
- Tom Kenny - Singing Toy Bear (voice)
- Jill Latiano Howerton - Diana Vosh
- Minka Kelly - Stacey
- Christopher Michael - Doctor
- Ashley Eckstein - Susan
- Cameron Lee - Student
- Mandy Musgrave - High School Girl
- Mark Matkevich - Devin Malone
- Lucy Hale - Hazel
- Miracle Vincent - Cashier
- Nikki SooHoo - Teenage Girl
- Johanna Braddy - Emily
- Paul Parducci - Coach Remmers
- Jeremy Rowley - Dancer Worker
- Eliza Swenson - Sabbath
- Nicole Andrews - Lady Cop #2
- Shelli Boone - Lady Cop #1
- Ted Lange - Mr. Calvert
- Ted Lange - Teacher
- Rene Cadet - Troy
- Michelle Dionne - Cute girl #1
- Katie Gill - Teri
- Tom O'Keefe - Dave
- D. Elliot Woods - Vince
- Toshi Toda - Karate Instructor
- Toshi Toda - Performing Center Owner
- Ari Zagaris - Fireman #1
- Charlet Chung - Teen Girl
- Mateo Arias - Reggie
- Joe Gnoffo - Theatre Goer #3
- Torrey DeVitto - Denise Woods
- Torrey DeVitto - Tori
- Stephanie Patton - Little Girl
- Kelly Heyer - Monica
- Braeden Marcott - Teacher
- Brent Tarnol - Taylor
- Allan Louis - Blaze
- Lorin McCraley - Jack
- Larry Thomas - Mr. Galloway
- Michael McKay - T-Rex
- Aimee-Lynn Chadwick - Student
- Jeremy Ray Valdez - Paul
- Clint Carmichael - Officer Becker
- Allison Andreas - Girl Scout
- Austin Basis - Skaggs
- Christian Vandal - Corey
- Allan Murray - Head of Security
- Troy Aguayo - Security Guard
- Kaylee DeFer - Cute Girl
- Zane Cassidy - Crazed Customer
- Daniele O'Loughlin - Nun
- Stewart Skelton - Popcorn Customer
- Wayne Thomas Yorke - Plumber
- Tony Longo - Janitor
- Brett Wagner - Ronnie
- Kate Miner - Michelle
- Frances Callier - Helen
- Lisa Canning - Reporter #1
- Terry Cooley - Citrus
- Jeff Witzke - Event Coordinator
- Jesse Heiman - Spectator at Concert
- Cole Williams - Drummer
- Heather Marie Marsden - Carly Roberts
- William Corkery - Pete
- Jenna Heffernan - Leah
- Richard Wharton - Hobo
- Anthony K. Lewis - Big Tough Guy
- Chris Neff - Tough Kid
- Riley Schmidt - Guy
- Bradley Snedeker - Buddy
- Kirker Butler - Man
- James Immekus - Drew
- Abigail Mavity - Pigtail Girl
- Jennifer Holland - Girl
- Paul Gleason - Mr. Thompson
- Robin Sydney - Jackie
- Andy Daly - Movie Goer
- John Ducey - Gail's Husband
- Laura Putney - Gail
- Michael Russeck - Spring Breaker
- Carlos Alazraqui - Orajio Hidalgo
- Chasen Lee - Judge 1
- Scot Zeller - Pharnsworth
- Ronald Hunter - Yonka
- Wesley Mann - Blemin
- Natalija Nogulich - Yeesta
- Ajay Vidure - Steve
- Ryan Alvarez - Robbie Bernstein
- Jason Maves - Brent
- Sofia Sokolov - Liza
- George Doty IV - Biohazard Doctor
- George Doty IV - Team Doctor
- Brooks Utley - Mustache Man
- Ashley Chase - Nurse
- Marisa Lauren - Nurse Kelly
- Kathryn Melton - Dr. Lindy
- John O'Hurley - Dr. Carlson
- Marisol Ramirez - Nurse
- Rachel Shumate - Nurse
- Fred Stoller - Lenny Spodnick
- Oprah Winfrey - Oprah Winfrey
- Brycen Counts - Football Player
- Brandon Brendel - Football Player
- Elaine Murphy - Harpist
- Harry S. Murphy - Mr. Crenshaw
- Erica Shaffer - Mrs. Crenshaw
- Tara Lynne Barr - Katie
- Kevin Farley - Cop
- Kevin Farley - Bud
- Ridge Canipe - Neil
- Joyce Lee - Teacher
- Justin Martin - Student
- Annabelle Milne - Twin Girl #1
- Kris Palm - Tyler
- Bill Parks - Mean Kid
- Jordan Wright - Sammy
- Laura Ortiz - Cute Girl
- Shea Parker - Teen Guy
- Lou George - Mr. Farrow
- Lou George - Judge
- Terrance Thomas - Boy Scout #1
- Hayden Thompson - Theater Thug
- Cherilyn Wilson - Sam
- Roderick McCarthy - Officer Jackson
- Carolyn Morse - Angry Woman in Line
- David Wachs - Uppity Hotel Concierge
- Michael Leland Burton - Security Guard
- Benjamin Byron Davis - Jerk in Line
- Maggie Wheeler - Denise
- Gabrielle Carteris - Dr. Phyllis
- Jesse Hlubik - P.A. #2
- Shannon Kingston - Drake's Pretty Teen Girl
- Gino Montesinos - Detective Jamison
- Matt Newton - Deegan
- Summer Bishil - Tabitha
- Lane Napper - Andy
- Lane Napper - Academic Bowl Host
- Denise Gossett - Woman
- Keisuke Hoashi - Hospital Administrator
- Anne Marie Howard - Producer
- Ben Hermes - Bodyguard #1
- Wayne King - Bodyguard #2
- Bryan Gildner - Oprah Fan
- David Daskal - Delivery Man #2
- Buddy Lewis - Animal Control
- Jesse Burch - Cop
- Michael Kopelow - Delivery Guy
- Michael Kopelow - Delivery Man #1
- E.E. Bell - Leslie
- Adam Huss - Spencer
- AJ Wedding - Ryan
- Lazarus Jackson - Painter
- Paul Rust - Ethan
- Brie Gabrielle - Jasmine
- Marisa Guterman - Goth Girl
- Harry Karp - Horrace
- Peter Kwong - Mr. Curtis
- Allie Rivera - Tammy
- Carissa Capobianco - Short Girl
- Dianna Agron - Lexi
- Ronobir Lahiri - Reporter #1
- Patrick Thomas O'Brien - Minister
- Steve Tom - Henry Doheny
- Paul Denniston - Scott
- Eddie Driscoll - Sergeant Doty
- George Frangides - Mr. Nadel
- Jillian Murray - Drake's Girl
- Jillian Murray - Cute Girl
- Skyler Gisondo - Tyler
- Carolyn Hennesy - Mrs. Abernathy
- Jessica Landon - Collette
- Rayna Tharani - Petty Woman
- Gabrielle Christian - Lucy
- Jake Farrow - Gavin
- Brittany Curran - Carly
- Shiloh Fernandez - Julio
- Greg Hain - Anthony
- Dan Mott - Gary
- Sarah Christine Smith - Christine
- Eddie Alfano - Cop #2
- Stephan Bender - Teen Guy #2
- Marta Cross - Girl
- Curtiss Frisle - Teen Guy #1
- Steve Kramer - Stan the Car Man
- James Matthews - Dr. Favershim
- Matthew J. Evans - Robbie
- Emily Kosloski - Customer #1
- Tony LaThanh - Roki
- Cole Schaefer - Security Guard #2
- Lauren Shiohama - Kat
- Byron Washington - Security Guard #1
- Neilen Benvegnu - 8th Grade Boy #1
- Christopher Emerson - Chad
- Donna Pieroni - School Nurse
- Josh Sussman - Clayton
- Tom Virtue - Mr. Roland
- Matthew Thompson - Student #5
- Jonna Walsh - Heather
- Teddy Lane Jr. - Officer Dobbins
- Jeff Braine - Thornton
- Haran Jackson - Boom Guy
- Martin Klebba - Nug Nug
- Brittani Noel - Girl #2
- Douglas Tait - Doorman #2
- Nathan Kress - Toplin (uncredited)
- Michael Albala - Rabbi Danziger
- Yvette Nicole Brown - Helen
- Scott Halberstadt - Eric Blonowitz
- Samantha Cope - Andrea
- John Fugate - Jack
- Anthony Holiday - Buzz
- J Ferguson - Junior Executive
- Julia Duffy - Mrs. Hayfer
- Cathy Shim - Leah
- Allison Scagliotti - Mindy Crenshaw
- Jerry Trainor - Crazy Steve
- Race Owen - Owen / Mixer
- Lauren Benz Phillips - Carrie
- Terry Ray - Wedding Coordinator
- Thea Vidale - Lula Dubois
- Brenda Vivian - Collette
- Joseph Will - Alan
- Jason Nash - Waiter
- Alec Medlock - Craig Ramirez
- Diana Pérez - Darcy
- Billy St. John - Priest
- Dan Schneider
- Chris Robinson
AnnaSophia Robb interpreta a Liza en la serie.
Martin Klebba hace el papel de Nug Nug.
Drake Bell interpreta a Drake Parker en la serie.
Josh Peck interpreta a Josh Nichols en la serie.
Miranda Cosgrove hace el papel de Megan Parker.
Jonathan Goldstein interpreta a Walter Nichols en la serie.
Nancy Sullivan interpreta a Audrey Parker-Nichols en la serie.
Capítulo disponible en las siguientes plataformas:
