- Ricky Schroder - Dr. Dylan West
- Richard Biggs - Dr. Milo Morton
- Arjay Smith - Kyle
- Eileen April Boylan - Araya Fujito
- Andrea Gabriel - Regina Bonfiglio
- Kyla Pratt - Donna Jenkins
- Amelia Marshall - Olivia Butler
- Lisa Eichhorn - Madeline
- Alley Mills - Rhonda LaCouer
- Charlotte Rae - Maude
- CCH Pounder - Libby Bell
- Tia Mowry - Keisha
- Holly Robinson Peete - Halle Ellis
- Ana Ortiz - Elena Delgado
- Rachael Crawford - ER Doctor
- Ashley Tisdale - Sherry Lowenstein
- Alex Rice - Teri Lavadour
- Alisa Reyes - Sonia
- Giovonnie Samuels - Renee Marsh
- Elizabeth Gracen - Serena Mason
- Karen Malina White - Constance 'Connie' MacRane
- Amanda Stepto - Mary
- Jeffrey D. Sams - Jack
- Camille Winbush - Vinetta
- Dee Dee Davis - Anna Cortese
- Delane Matthews - Teri Ann
- Jacqueline Obradors - Dolores Rivera
- Robyn Lively - Connie
- Julius Carry - Art Lewis
- Ken Davitian - Cabbie
- Kim Fields - Lottie
- Ellen Pompeo - Quincy Dunne
- Janina Gavankar - Nurse Juni
- Saundra Quarterman - Jane Hogan
- Ashley Jones - Shelly Lane
- Laura Moss - Sheryl
- Sara Gilbert - Charlayne
- Kathy Ireland - Amber Hutton
- Kimberlee Peterson - Penny Pointer
- Davenia McFadden - Roxy
- Taraji P. Henson - Crystal
- Morgan Flynn - Lizzy Campbell
- Alice Amter - Mey Said
- Wayne Duvall - Dixon
- Peter MacKenzie - Asher
- James Eckhouse - Rabbi Yaverbaum
- Jill Eikenberry - Councilwoman Evelyn Barrett
- Angelique Bates - Natalie
- Anthony Azizi - ER Doctor
- Sandra Nelson - Kathleen Anderson
- Kimberly Scott - Mrs. Rose Jenkins
- Greg Rikaart - Traylor
- Dakota Fanning - Edie's Girl
- Candice Azzara - Lorraine Mills
- Suzanne Ford - Mrs. Fitzgerald
- Albert Hall - Reverend Hayes
- Christopher Marquette - Marc Delgado
- Diane Ladd - Annabelle Lee Stowe
- Lisa Darr - Susan Jackson
- Michael Paul Chan - Dr. Dexter Chen
- Julie White - Caitlin Crawford
- Freda Foh Shen - Mrs. Simmons
- Lisa Lackey - Athena Kelinopoulos
- Robert Foxworth - Dr. Ezra Stowe
- Wendy Phillips - Michelle Freid
- Novie Edwards - Gloria
- Jennifer Weston - ER Doctor
- Kellie Waymire - Angela
- Joe Spano - Jonathan Freid
- Katherine Helmond - Cicely Nordeco
- Joe Colligan - Rony
- Debbi Morgan - Chloe Simons / Cora Simons
- Holland Taylor - Lillian Pynchon
- Haskell V. Anderson III - Art Instructor
- Pamela Dunlap - Nurse Grinaldi
- Whoopi Goldberg - Dr. Lydia Emerson
- Terrence Flack - ER Dr. Terence
- Jurnee Smollett - Ruby
- Mia Riverton - Paramedic Lavonne
- Vanessa Mizzone - Charlotte
- Danica McKellar - Natalie Pascal
- Harley Graham - Sophie
- Malika - Sanya Valdez
- Khadijah Haqq McCray - Tanya Valdez
- Fran Drescher - Irene Slater
- Nestor Carbonell - Jonas Ray
- Kelly Gould - Molly Molika
- Shelby Leverington - Judge
- Camryn Manheim - June
- John D. Kim - Delivery Guy
- Sierra Taylor - Tracy LeCraw
- Colton Shires - Mikey Simmonds
- J. Anthony Pena - Raoul
- Jenna Fischer - Camille Freemont
- Jeremy Sumpter - Randy
- Sheeri Rappaport - Melissa Mauls
- Amelia Rose Blaire - Jane Kellher
- Kat Graham - Ashley Collins
- Ashley Benson - April
- Hunter Brochu - Adam Mided
- Chelsea Russo - Lauren Jackson
- Mishu Vellani - Diane
- Natalie Charles - Mrs. Pullman
- Martha Chaves - Brenda
- Diego Fuentes - EMT
- Caroline Gillis - Clara
- Lisa Hynes - Joan
- Paul Robert Langdon - Marc Delgado
- Linlyn Lue - Nurse
- Liisa Repo-Martell - Jessie
- Lucille Soong - Mrs. Lum
- Wayne Lam - Administrative Assistant
- Marianne Moroney - Audrey
- Paula Malcomson - Trish
- Eamon Behrens - Big Angry Guy
- Alicia R. Cole - Sherry
- Joel Fabiani - Jay Harper
- Cici Lau - Mrs. Hong
- Rebecca Metz - Mary in Chat Room
- Wen Yann Shih - Jasmine Hong
- Ian Barford - Bill Moler
- Tegan West - Nathan
- Jami Bassman - Ruth
- Chase MacKenzie Bebak - Edie's Boy
- Greyson Erik Pendry - Charlie
- Susie Schelling - Nurse
- Jenni Blong - Tina
- Jennifer Echols - Myra
- Curtis Jackson - Second Look / Ruby
- Kristine Louise - Barb
- Michael Mahonen - Anonymous / Joe
- Shirley Roeca - Faye
- Michael Spound - Scott
- Jules Douglas - Emilio
- Mary Jo DuPrey - Sandra
- Erica Vittina Phillips - Janet Lewis
- Nicki Micheaux - Lori
- Verda Bridges - Chanel
- Helen Cates - Nancy
- Gerald Emerick - ER Doctor
- Caroline Fogarty - Sunny
- Jeff Harlan - Nelson Wandell
- Lynn Ann Leveridge - Night Nurse
- Donna M. Perkins - Amber
- Jean Sincere - Edith
- Mike White - LTCOL Bill Fortier
- Melinda Miamor - Vickie
- Christine Healy - Patricia Langford
- Alex Mann - Vinnie
- Kelly Wolf - Rosie
- Noor Shic - ER Doctor
- Judith Montgomery - Elaine
- Amy Correa - Trini Santos
- Seraiah Carol - Donna
- Jonathan Tipton Meyers - ER Doctor
- Bee-Be Smith - Dr. Lenore Friedland
- Sara Van Horn - Irene
- Tracy Vilar - Marisol Santos
- Kristina Lear - Meredith O'Neill
- Tim Williams - Sean O'Neill
- John Allsopp - Dr. Geisler
- Lindsay Beamish - Audrey Hammond
- Joyce Guy - Leila
- Venus DeMilo Thomas - Carol
- Paul Terrell Clayton - Jay Fields
- Jenette Goldstein - An unnamed friend
- Molly Hagan - Grace Duke
- Michael Harney - Edward Duke
- Robert Madrid - Truck Driver
- Deborah Puette - Lorraine
- Scott Terra - David Tyrell
- Bahni Turpin - Charlotte Gould
- Jeana Blackman - Candy
- Ruth de Sosa - Sally Riley
- Jeff Feringa - Pearl
- Jerry O'Donnell - Dick Shelton
- Bunnie Rivera - Marti
- Toby Smith - Toinette
- Amy Tolsky - Jean
- Christienne Wadsworth - Emily Cartwright
- Kate Asner - Hollis Pointer
- Benjamin Brown - Lab Tech
- James Logan - Paramedic Smith
- Lisa Ann Orkin - Chat Room
- David Purdham - Penny's father
- Danica Sheridan - Sheila
- William Forward - Dr. Alan Mendel
- Stacy Solodkin - Flory
- Keri Marrone - Joyce
- Yelba Osorio - Lisa Bernstein
- Ramy Zada - Abdel Said
- Barry Sigismondi - Detective Stevens
- Michael Gabriel Goodfriend - ER Doctor
- Andy Clement - Puppeteer
- Cynthia Ettinger - Kendall Davis
- Bruce Katzman - Dr. Lank
- Taylor Nichols - Guy Davis
- Katy Selverstone - Patty Roland
- Alice Frank - Jenny
- Eileen Galindo - Irma Lopez
- Michael Harrity - Cop
- Eddie Kehler - Sammy
- Andy Kreiss - Milton
- Joshua Swanson - Zackary Branson
- Deanne Bray - Sonny
- Kate Connor - Anita
- Elyse Dinh - Nurse
- Troy Kotsur - Lars
- Philip Lester - Gil
- Billy Maddox - Dr. Zane Gray
- Dawn Saucier - Chamayne
- Bitty Schram - Juno Bouvoir
- Stan Sellers - Dr. Andre Pepper
- Frank Sharp - Policeman
- Don Snell - Dr. Sherman Millstein
- Meredith Thomas - Karen
- Annie Wood - Molly
- Karina Arroyave - Alicia Perez
- David Barrera - Charlie Perez
- Paige Carter - Paramedic
- Cee Cee Michaela - Noreen
- Cee Cee Michaela - Aidelia
- Trae Ireland - Baseball Player
- Lainie Kazan - Mrs. Biancavilla
- Jane Macfie - Sadie
- Jane Macfie - Sandy
- Norm Lewis - Mr. Phillips
- Karina Logue - Kimber
- Gary Riotto - Jayse Wineberg
- William Salyers - ER Doctor
- Sandra Thigpen - Paige Phillips
- James Adam Tucker - Nathan
- Jerry Gelb - Ken King
- Ana Guigui - Nina
- Damien Leake - Principal
- Wendel Meldrum - Eleanor Vogel
- Jenni Pulos - Sandy
- Cece Tsou - Mimi
- Rick Zieff - Vic Nabokov
- Emil Beheshti - Ray Roy
- Joel Brooks - Doctor Hogan
- Maria Carmen - Elena Torres
- Margaret Emery - Cindy
- Henri Lubatti - 'Mitch' Mitchell Tyler
- Abigail Mavity - Raquel
- Derrick L. McMillon - Police sergeant
- Jenny O'Hara - Nancy
- Paul Tigue - Flight Attendant
- Joey Vieira - Eddie
- Masasa Moyo - Talette
- Masasa Moyo - Anne
- Duana Knight - Scarlett
- Stephanie Silva - Young Mother
- Tangie Ambrose - Dee Cotter
- Carmen Argenziano - Monsignor Nicholas Rinaldi
- Annie Corley - Teresa 'Father Terrence' Valentine
- T.L. Brooke - Leanne
- T.L. Brooke - Angela
- Ginny Harman - Mom
- Rick Lenz - Joe Tucker
- Mary Rings - E.R. Nurse
- Vera Yell - Jazma
- Rhonda Collier - Young Nurse
- Betty Freeman - Nurse
- Louisette Geiss - Marissa
- Jossara Jinaro - Felice Ramirez
- James Avery - Harold Jenkins
- Burt Bulos - Paramedic Jones
- Tracy Letts - Ken
- James Lew - Cop
- Maia - Woman Patient
- Lara Phillips - Angie
- Gabrielle Carteris - Freddie Gosling
- Cleo King - Claudia Falder
- Giancarlo Esposito - James 'Junior' Bell
- Christopher Comes - Ruben
- Jonathan Fahn - Trenchcoat
- Alex Morris - Stanton
- Emilie Beck - Lois
- Emilie Beck - Darcy
- David Reynolds - Delivery Guy
- Frances Gray - Wanda
- Robair Sims - Gang Banger
- Michelle Horn - Jesse Campbell
- Shauna Stoddart - Dr. Campbell Patient
- Brian Kerwin - Leslie Campbell
- Rona Benson - Lorette
- Kim Evey - Sammi
- Michelle Joyner - Celine
- Sally Kirkland - Stella Riggs, Peter's Mother
- Diana Uribe - Jennifer Alonzo
- Troy Winbush - Ray Ellis, Halle's Husband
- Zylan Brooks - Pregnant Woman
- Christine Elise - Captain Gloria McKinney
- Shirell Ferguson-Coleman - Deb
- Sam Hennings - Colonel Bomfeld
- Cathy Herd - Tess Conway
- Lindsay Hollister - Margie Sinowski
- Star Jones - Jenna Owens
- Elise Muller - Skinny Minnie
- Christopher Neiman - Steve Kaplan
- Suzanne Voss - Ruth
- Sanetta Y. Gipson - Velvet
- Sue Cremin - Woman in Chat Room
- Anne-Marie Johnson - Nurse Doreen Collins
- Derick Alexander - Cop
- Mary J. Blige - Simone Fellows
- Javier Calderon - Simone's Guitarist
- Julie Nunis - Rita
- Julie Nunis - Angela
- Julie Nunis - Drusilla
- Julie Nunis - Impatient Lu Patient
- Julie Nunis - Sahron
- Rosanna DeSoto - Dr. Elena Gomez
- Keisuke Hoashi - Hematologist
- Gregory Vahanian - Anesthesiologist
- Renée Victor - Isabel Santana
- Comika Hartford - Karen
- Ford Austin - Mr. Smith
- Tony Becker - Ted Harris
- J.C. Brandy - Molly Harris
- Viveka Davis - Eileen O'Connell
- Page Leong - Dr. Fields
- Paul Linke - The Warden
- Elisa Perry - Lakeisha
- Rick Scarry - Judge Lewis
- Lourdes Benedicto - Carmen Infante
- Kent Faulcon - Melvis 'Mel' MacRane
- Patrick Flanagan - Paramedic Burns
- Benton Jennings - Worthington
- Michael Pasternak - Brownie
- Marcia Cross - Linda Loren
- Maia Danziger - Ms. Keach
- Lesley Fera - Anne
- Howard S. Miller - Dr. Walter Thompson
- Laurie O'Brien - Arlene Billings
- Taira Soo - Girl
- Mari Weiss - Ronni
- Matisha Baldwin - Shante
- Susan Blakely - Camille Cantrell
- Cara DeLizia - Felicity Farber
- Christopher Naoki Lee - Kevin
- Zeus Mendoza - Father Perez
- Alem Brhan Sapp - Zeke
- Heidi Swedberg - Celia Farber
- Keiko Agena - An-Soo 'Alison' Kim
- Valerie D. Young - Florinda
- Brad Kalas - Martin
- Tsai Chin - Jin Jae
- Teri Garr - Mimi Stark
- Gwen Holloway - Dr. Cook
- Bianca Lawson - Esperanza Maldonaldo
- Dana Lee - Mr. Kim
- Sharon Omi - Mrs. Kim
- Craig Tsuyumine - James Ito
- Phil Abrams - Dr. Weisbaum
- Gina Hecht - Hannah Yaverbaum
- John Laughlin - Tom Wolenski
- Kristen Shaw - Faith Wolenski
- Stacy Francis - Carrie
- Tom Beyer - Technician
- Caitlin Crosby - Erin Burr
- Richard Lawson - Alton Clayborne
- Joanna Miles - Mrs. Fielding
- Netfa Perry - Poppy
- Patrice Pitman Quinn - Vonda Emory
- James Remar - Guy Falls
- Leslie Stevens - Mary Hines
- Tanjareen Martin - Carmel
- Oksana Baiul - Irina Kostrova
- Sonia Kazarova - Mother of asthmatic
- Don Michael Paul - Harry Burr
- Lori Rom - Morgan Fielding
- Joe Camareno - Del
- Matthew Abe - ER Doctor
- Matthew Abe - Worker
- Jack Donner - Josiah / Amish Elder
- Jeffrey Gorman - Doug Carmichael
- Kathy Griffin - Matchmaker
- Diane McBain - Lovey Carmichael
- Ken Phillips - OR Tech
- Ken Phillips - Dr. Phillips
- Wolf Muser - Amos Lapp
- Michael Rothhaar - George Wales
- Samantha Thomas - Lila
- Hayley DuMond - Candice Oakley
- Cecil Hoffman - Pro-Life Activist
- Ray Valenti - Young mom
- Lisa Ann Walter - Rita Harper
- Shania Accius - Angie
- Reynaldo Gallegos - Rico
- Jason Kravits - Dr. Idinger
- Tina Lifford - Brenda Babson
- Amber Moore - Myra
- Ion Overman - Dr. Steph
- Bonnie Root - Shay Phillips
- Inger Tudor - Ginny Sheer
- Mandy June Turpin - Alice
- Alfred Woodley - Cleon
- Julie Ann Heck - Pretty Young Nurse
- Roger Stoneburner - Bald Creep
- Tammy Kaitz - Fiona Appleby
- Jenny Mollen - Blonde
- Terrie Snell - Mrs. Budderworth
- Ariana Thomas - Marian
- Kristin Carey - Carol-Anne
- Valerie Cruz - Almira
- Sheri Foster - Mary Muskegon
- Ralph Garman - Dratch
- Kristina Hayes - Natalie
- Kim Little - Laurie Brooks
- Zahn McClarnon - Joe Lavadour
- Kelly Jo Minter - Vielle Montoya
- Rebekah Ryan - Kadi
- John Short - Commercial Director
- Bill Stevenson - Gerald
- Kyli Santiago - Daria
- Americus Abesamis - Dr. Americus
- Nikita Ager - Nurse Julie Masters
- Anne Gee Byrd - Martha Edwards
- Emy Coligado - Nurse Betsy Welling
- Trie Donovan - Melissa
- Nicole Forester - Heather Grimes
- Jonathan Fraser - Dr. Landgraff
- Michelle L. Gardner - Janelle
- Jeremy Guskin - Med Student Mayer
- Eric Lutes - Trevor
- Rodney Rowland - Jake Dantona
- Tushka Bergen - Emily
- Bryan Coffee - Blood Bank Bobby
- Kevin Fry-Bowers - Worker
- Kevin Fry-Bowers - Homicide Detective
- Austin Marques - Joey
- Myrna Niles - Mother Superior
- Roy Werner - Theodore Charlton
- Bradley White - Eric Wolfe
- Julie Dretzin - Ginny Driver
- Michelle Forbes - Jill Sorenson
- Bryan Greenberg - Kent
- Gregory Harrison - Dr. Randolf Kilner
- LaTitia-DeLaine - Sima
- Dianna Miranda - Teresa Echeverria
- John Gipson - Cougher
- Charlie Talbert - Bluto
- Larry Vigus - Gunshot Victim
- Monique Edwards - Coach Lisa
- Reagan Gomez-Preston - Briette
- Ameenah Kaplan - Patsy
- Michelle Noh - Sall
- Baadja-Lyne Odums - Ardelle Davis
- Juliette Jeffers - Rhonda
- Juliette Jeffers - Liposuction Patient
- Antoinette Peragine - Chi Chi
- Michael Shepperd - Detective Armstrong
- Warren Tabata - Neonatologist
- Richard Tanner - Jeff Bader
- Michelle Azar - Marian
- Ken Garito - Zahn
- Mel Harris - Biddy Hightower
- Chris Heuisler - Undergrad
- Don McManus - Monty Hightower
- Lidia Pires - Wanda
- David Spates - Paramedic Watts
- Tara Chocol - Ricki
- Lauren Cohn - Candy
- Megan Follows - Dana's Doctor
- Taylor Sheridan - Tucker
- Bill Bradshaw - Pediatric Doctor
- Finn Carter - Velma
- Cynthia Cervini - Coral
- Timothy Lee DePriest - Young Punk
- Robin Gammell - Dana's Lawyer
- Arye Gross - Gene Withers
- Tim Kelleher - Willie Parnell
- Ian 'Blaze' Kelly - Young Punk
- Kila Kitu - Susanna
- Ted Marcoux - Cal
- James Pickens Jr. - Dr. Everett Sloane
- Pamela Shaddock - Pedes Nurse
- Allisyn Ashley Arm - Wendy Withers
- Bradley Stryker - Franky / Young Punk
- Annie Kitral - Mrs. Kovacek
- Annie Kitral - Irene Kiezlowski
- Jonelle Allen - Connie
- Lacey Kohl - Paula
- Deron McBee - the Winged Wonder
- Rick Peters - Dave
- Suzanne Whang - Dr. Sporich
- Garrett M. Brown - Karl
- Ursula Burton - Missy Ahmanson
- Lacey Chabert - Mary
- Katsy Chappell - Becca
- Ingrid Coree - Nurse
- Delaina Mitchell - Lisa Alvarez
- Nan Martin - Edith Strauss
- Stephen Gregory Foster - Dr. Blahnik
- Stephen Gregory Foster - Anesthesiologist
- Jennifer Milmore - Nurse Nina
- Robert Pine - Mr. Jurgenson
- Berta Richey - Kiki
- Natasha Weber - ER Nurse
- Lileé Anderson - Nurse
- Lydia Castro - New Mom
- Leyna Nguyen - News reporter
- Adina Porter - Malia
- Daniel Weiss - Michael
- Bonnie Bartlett - Edna Carlyle
- David Batiste - Len
- Emilio Borelli - Judge Hardwick
- Deana Carter - Georgia 'Georgie', homeless patient
- Ashley Crow - Christine Hedley
- Jamai Fisher - Little Girl
- Iyari Limon - Flaca
- Liliana Mumy - Annie
- Coleman McClary - Henry Hedley
- Rick Avery - Stunt Cop#
- Jimmy Bennett - Willy
- Chopper Bernet - Kidney Surgeon
- John Burton, Jr. - Police Officer
- Robert Kurcz - Sheila's dad
- Vanessa Morales - Sonia
- Luis Antonio Ramos - Alberto Mendoza
- Diane Salinger - Diane Winston
- Angela Sargeant - Principal Patterson
- Ken Strunk - Detective Mars
- Elizabeth Tobias - Mom
- Margaret Travolta - Sheila's Mom
- Sarah Culberson - Mom
- Roxanne Day - Ameenah
- Laura Johnson - Claudia Chase
- Thomas Vincent Kelly - Bill
- Kim Rhodes - Marla Cole
- Dawn Stern - Vicky Lloyd
- Ashley Brown - Ivy Grissom
- Melody Butiu - Paramedic Julia
- Shanola Hampton - Tracy Saunders
- Charles Kahlenberg - Representative
- Lisa Kron - Nooch
- Jan Munroe - Seymour
- Romy Rosemont - Isobel
- Johanna Watts - Sorority Girl
- Time Winters - Isobel's Husband
- Terry Woodberry - Physical Therapist
- Georg Stanford Brown - Admiral Thomas Carter
- K.K. Dodds - Jeri Greer
- Carla Jimenez - Becky
- Carla Jimenez - Annie
- David Figlioli - Derek
- Michael Krawic - Konicki
- Reggie Lee - Dr. Nakashima
- Alessandro Mastrobuono - Larry
- Randy Oglesby - Henry Bueller
- Kimberly Russell - Veralyn 'Vera'
- Susan Santiago - Gia
- P. Adam Walsh - Lincoln
- Dior Raye - Patty
- Robert B. Martin Jr. - Hyperbaric Tech
- Heather McComb - Cecelia 'Cissy'
- Peter White - Dr. Soames
- Amy Stewart - Lindsay Beckman
- Lisa Waltz - Dr. Doris Pasternak
- Kara Zediker - Mimi
- Bobbie Stamm - Lindsay's Mom
- Mashari Laila Bain - Crystal
- Miranda Kent - Angela Halloran
- Basil Wallace - Ezekiel Monroe-Howard
- Jayne Taini - Elmira
- Jayne Taini - Gladys Gray
- Cheryl White - Cassidy
- Julian Acosta - Miguel Arenas
- Dar Dixon - Code Doctor
- Anthony Holiday - Surgical Intern
- Nancy Calabrese - Kathleen Kitinka
- Fanshen Cox - Channing Arlington
- Cathy Lind Hayes - Lorraine
- Phyllis Katz - Nicole's Mom
- Tracey A. Leigh - Mariah
- Marguerite MacIntyre - Tori Davis
- Lynne Marta - Mrs. Callender
- Shani Pride - Rain
- Hanover Savas - Nicole
- Dorothy Sinclair - Flo
- Nicolas Surovy - Mr. Callender
- Joanna Lipari - Deborah Mayer
- Mikki Val - Bev
- Indira G. Wilson - Shanice
- Allison Andreas - Crying Girl
- Iris Bahr - Ronnie Vongolia
- Purva Bedi - Yasmin Fayed
- Adam Drescher - Mummer
- Lydia Blanco Garza - Myrel
- Joe Howard - Dr. Doster
- Sarah Ripard - Suma Fayed
- Mike Siegel - Sherman
- Christel Smith - Skye
- Kirk B.R. Woller - FBI Special Agent Randolph P. Lentz
- Haneefah Wood - Raleena
- Michael Peter Bolus - Tommy
- Erin Cardillo - Gayla
- Margarita Cordova - Olivia
- Anthony DiMaria - Ralphie Bonfiglio
- Adam Grimes - Smiley
- Cazimir Milostan - Staff Sergeant
- Yun Choi - Mindy's Ex-boyfriend
- Justin Shenkarow - Dusty
- Karimah Westbrook - Sandy
- Barbara Bain - Mrs. March
- Deirdre Lovejoy - Taylor
- Maia Madison - Woman
- Harve Presnell - Andrew 'Andy' March
- Brigid Brannagh - Abby
- Dyllan Christopher - Isaac
- Marcus Coloma - Caesar
- Eric Edwards - Jimmy
- Karen-Eileen Gordon - Maria
- Leann Hunley - Renee Van Dyke
- Kieran Mulroney - Dr. Bardem
- James Black - Joey
- Katherine Ann McGregor - Mere
- Eve Sigall - Heddie
- Sofie Calderon - Bonnie
- Sharmila Devar - X-Ray Tech
- Sylva Kelegian - Margie
- Sarah Lilly - Mrs. Fenton
- Ailsa Marshall - Blonde to end all blondes
- Ed Francis Martin - AA Counselor
- Annabelle Milne - Cute Nurse
- Rachel Rogers - Jamie
- Pia Glenn - Mona
- Jillian Henry - Erin McConnell
- Mollie Milligan - Darla
- Rita Moreno - Lydia
- Steve Ryan - Fire Chief
- Tim Ryan - Al McConnell
- Yelyna De Leon - Shar
- Yelyna De Leon - Patient
- Stacey Travis - Helen McConnell
- Ellen Bry - Emily Schmoen
- Johnny D'Agostino - Angry Customer
- William Stanford Davis - Doug - Aneesha's Boss
- April Grace - Aneesha Walker
- Jennifer Griffin - Psychiatric Ward Nurse
- Dawnn Lewis - Detective Wright
- Sean Vincent Biggins - Big Boss
- Jack Stehlin - Don Schmoen
- Kia Skrine - Teena
- Christina Ogunade - Staci
- Nicola Seixas - Marilla
- Suzanne Sole - ER Nurse
- Natsuko Ohama - Lenore
- Brian Patterson - Fireman
- Brian Morri - Mr. Smith
- Brian Morri - Paramedic
- Carol Abney - Beth Borden
- René Ashton - Malora
- Yvonne Delarosa - Emily Encerrado
- Lisa Pelikan - Babs Darner
- Lynsey Bartilson - Rina Dobler
- Spencer Garrett - Cal Wallace
- Candice Hamilton - Dorielle
- Jerry Hauck - Ben Franklin
- John Robotham - Businessman
- Maïté Schwartz - Marisa
- Meera Simhan - ER Nurse
- Doris Jung Usui - Waitress
- Stephanie Vogt - Amanda
- Mia Wesley - Donna Brodsky
- Patience Cleveland - Edith
- Donald Elson - Harold
- Ace Mask - Auctioneer
- Peter Spruyt - Ed
- Graham Beckel - Perkins
- P.J. Byrne - Levin
- Wendy Carter - Thea
- Michele Greene - Pam Sherr
- Gary Poux - ADA Ryan
- Jason Rath - Man
- Tasia Sherel - Woman
- Jason Stuart - Talk Show Host
- Donzaleigh Abernathy - Child Psychologist
- Judy Jean Berns - Mrs. Keach
- Andi Carnick - Diane
- Yvette Cruise - Donna
- Svetlana Efremova - Corrina
- Karen Hensel - Principal Washburn
- Eddie Jemison - Walter Shenckman
- Michele Kelly - Fran Cortese
- Wayne Lopez - Detective Rodriquez
- Dominic Pace - Cop
- David Ramsey - Jake Cortese
- Nikki Tyler-Flynn - June Shenckman
- Michael Butler Murray - Reporter
- Michael Faulkner - Michael
- Michael Faulkner - Finklestein
- Christinna Chauncey - Lori
- Monique Coleman - Tanya
- Kaitlin Doubleday - Julie Windsor
- Fred Kronenberg - Dr. Hillerman
- Kayla Mae Maloney - Erin
- Angela Martinez - Reporter
- Joan McMurtrey - Glenna
- Kiki Melendez - Maggie
- Mariah Shirley - Nurse
- Jennifer Siebel Newsom - Nancy Donahue
- Christie Lynn Smith - Cari Ferguson
- Charlie Weirauch - Bertram Jones
- Jane Yamamoto - Tawny Small
- Catherine Ai - Mrs. Pham
- Lizette Carrión - Sarita Ballard
- Randi Cee - Mrs. Turner
- Jamison Jones - Trey Jeffers
- Drew Matthews - Dewey
- Rolando Millet - Mr. Brooks
- Sumalee Montano - Med Student
- Eric Pierpoint - Dr. Sullivan
- Elizabeth Rivera - Concerned parent
- Kim Staunton - Owen's Mother
- Michael Zelniker - Dr. Janovitch
- Callan White - Monique Wallace
- Samantha Adams - Paramedic Shelly
- Cyia Batten - Trina
- Keith Lal - Cabbie
- Paul Messinger - Sean
- Julia Pace Mitchell - Kyra
- Richard Topol - Dr. Josh Gelfand
- Richard Topol - Attending
- Katie Mitchell - Janice
- Alan Naggar - A / V Nerd
- Yomi Perry - Ramona
- Matt Price - Barry
- Claire Rankin - Claire
- Marilyn Rising - Stella
- Gabrielle Sanalitro - Patti
- Tammy Trull - Lourdes
- Laila Ali - Lyla
- Iris Almario - Quelinda
- Lee Brooks - Bronchoscopy Guy
- Mireille Enos - Fern
- Gene LeBell - Referee
- Kathy McGraw - Mrs. Herring
- Ed O'Ross - Mr. Furlong
- Janet Rousseau - Kathy
- Shawn Woods - Wendell
- Peter Allas - Spiro
- Anastasia Basil - Athena
- Daphne Bloomer - Cherisse
- Alyson Croft - Karen Splenderer
- Joel David Moore - Dan
- Cedric Pendleton - Maurice Hawkins
- Damani Roberts - Junior
- Erica Sullivan - Terri
- Deborah Vancelette - Mother
- Michael Winbush - Cop
- Sarah Aldrich - Mona Jeffers
- Daniel Brooks - Mody
- Jo Deodato Clark - Sophie
- Sam Feuer - Yosef
- Gretchen Koerner - Nurse
- Andrea Marcovicci - Dorothea Freemont
- Jeff Marlow - Rob Jeffers
- Leigh Taylor-Young - Catherine Beecher-Douglas
- Dylan McKnight - Ephram Steiner
- Tanya Boyd - Rachel's Mother
- Carlease Burke - Delane
- Alexis Corey - Emma
- Julie Dolan - Woman
- Lakeith S. Evans - Leon
- Bob Glouberman - Bug Scientist
- Rachel Grate - Mandy
- David Hadinger - Chester
- Michael Hagiwara - Japanese Gardener
- Nicholl Hiren - Kymberly
- Shelley Long - Lauren Chase
- Sandy Martin - Iris Rawlings
- Jennifer Nyholm - Woman
- Elsa Raven - Miss Tidwell
- Timilee Romolini - Journee Rawlings
- Darnell Suttles - Sid
- Evan Arnold - Helmer
- Jonathan Banks - Frank Hardwhyck
- Zolee Griggs - Amber
- Christopher Hoffman - Jerry
- Al Kaplon - Softball Umpire
- Johnny Liska - Georgio
- Virginia Reece - Lola Hardwhyck
- Sandy E. Scott - Officer Ekhart
- Lauren Stamile - Marcie
- Peggy Stewart - Elmira
- Diahann Carroll - Eve Morton
- Peter De Anda - Milo's father
- Michael Hagerty - Eric
- Tina Holmes - LeeAnn
- Ashlee Levitch - Michelle
- Don Perry - Isaac Grayson
- Pat Skipper - Jerome
- Nicholle Tom - Sharon / Cherie / Sharona
- Eileen Brennan - Evelyn Knightly
- Monica Calhoun - Paige Wheeler
- Ashley Gardner - Nina, Evelyn's Daughter
- Kathryn Joosten - Mrs. Nolan
- Stephanie Nash - Dr. Ferris
- Shondrella Avery - Etta
- MC Lyte - Nikki
- John Rubinstein - Lyle LaCouer
- Erin Sanders - Paige Jackson
- William Bassett - Spelling Bee Judge
- T.V. Blake - Charisse
- Andrea Bowen - Sara Buck
- Ariel Gade - Jewel Wheeler
- Juliet Landau - Lorraine
- Deborah Landis - Stephanie
- Rhes Low - Vic Trundle
- Ruben Avitia - Royal Bodyguard
- Joanne Baron - Brenda
- Erin Chambers - Madison
- Elizabeth Dement - Connie
- Peter A. Hulne - Guest star
- Ajay Mehta - Masood Nazir
- Matthew Yang King - Dr. Matt Linn
- Matthew Yang King - First Year Medical Student
- Ron Morehouse - Wyatt
- Kavi Raz - Nawaz
- Sheetal Sheth - Shaheena
- Stacy Arnell - Vanessa
- Kim Chueh - Koo
- Brad Grunberg - Lewis
- Henry LeBlanc - Augustus
- Kinna McInroe - Marnie
- Jillian Armenante - Francine 'Frankie' Biancavilla
- Stacy Barnhisel - Joanna Heely
- Juliette Goglia - Gaby Heely
- Daniel Graves - Dr. Klipstein
- Erik Jensen - Gaby's Father
- Shannon O'Hurley - Ria Prince
- Grant Show - Ben Sanderson
- Charlayne Woodard - Margaret Morganfield
- Mary Castro - Vivian
- Frank Elmore - Show Host
- Roxanne Hart - Cheryl
- Jill Holden - Cornelia Beamish
- Emily Lucas - Dora
- Christian Pikes - Terry
- Steve Stapenhorst - Octavian CEO
- Jay Acovone - Jimmy Gentile
- Laura Cerón - Taryn
- Dennis Cockrum - Dan Fuller
- Bianca Collins - Hailey
- Marisa Echeverria - Sandy
- Christine Estabrook - Berri Kaplan
- Christian Hutcherson - School yard partner
- Deborah Offner - Melinda Fuller
- Wendell Wright - Judge
- Felicia Day - Jesse's Friend
- Ashley Eckstein - Becca
- Treisa Gary - Miranda Banks
- Jon Hershfield - Paramedic Gordon
- Vladimir Rajcic - Reunion Friend Dave
- Daryl Anderson - Trevor Griffith
- Wendy Braun - Pam Gorman
- Sarah Joy Brown - Perry
- Kathleen Mary Carthy - Attorney Ms. Valenz
- Lora Martinez-Cunningham - Tanya
- Parker McKenna Posey - Lily
- Dohn Norwood - Amber's Tour Manager
- Rozonda 'Chilli' Thomas - Amber Steele
- Erin Underwood - Reggie
- Tanya Wright - Lily's Mother
- Bill Cleavelin - Short Guy
- GiGi Erneta - Alison
- Cesar Garcia - Drug Dealer
- Lee Garlington - Cammie's Mother
- Nichelle Hines - Najife
- Thomas Kopache - Michael Wilkins
- Kaleigh Krish - Jordan
- Yvonne Huff - Paramedic Ally
- Shawn Carter Peterson - Artistic Guy
- Susan May Pratt - Cammie
- Selma Stern - Grandmother
- Mageina Tovah - Trinity
- Jessica Tuck - Rachel
- Steven Allerick - Guy
- Charles Duckworth - Jerome
- Sabrina Gennarino - Marla Skaggs
- Lauri Hendler - Suzanne Simmonds
- Tracy Howe - Coach Joey Donegan
- Meredith Scott Lynn - Joy Severs
- Paul Schulze - Mayor Arnold Sweeney
- Peter Trencher - Julius Jordan
- María Costa - Clarisa Morales
- Shi Ne Nielson - Nurse Selden
- JoBeth Williams - Margie
- Jackie Geary - Caroline
- Elizabeth Sampson - Stephanie
- William-Christopher Stephens - Therapist
- Tamlyn Tomita - Dr. Nash
- Keke Palmer - Sarina
- Sharon Brathwaite-Sanders - Mrs. Rom
- Jay Alan Christianson - Adam Gracen
- Katy Kurtzman - Lorinda Gracen
- Dea Lawrence - Dr. Schwartz
- Lauren Pritchard - Tori
- Kimberly Quinn - Linder Kerrigan
- Blake Robbins - Morgan Benedicto
- Quinn Sullivan - Ruby
- Suzette Tomlinson - Paulina
- Lynn Whitfield - Dr. Marshall
- Preston James Hillier - Policeman
- Indigo - Mikela Johnson
- Michaela Watkins - Julia
- Isabella Way - Student
- Dey Young - Sylvia
- Chad Brokaw - Video Store Clerk
- C. Stephen Browder - Agent Sanders
- Michael Bunin - A.D.
- Brenda Canela - Shandra
- Enya Flack - Amanda Lindquist
- Amanda Fuller - Tally
- Shirley Jordan - Ebony Weston
- Jae Suh Park - Daughter Kim
- Albie Selznick - Graham
- Nick Spano - Dr. Schwartz
- Cheyenne Wilbur - Waiter
- Zoë Yeoman - Senators' Wife
- Shelly Cole - Gina Perry
- Pat Crawford Brown - Millie - Pharmacist
- John Griffin - Paramedic Newton
- Kelley Hazen - Dr. Evelyn Vince
- John Kelly - Gym Coach / Announcer
- Maria McCann - Syd
- Tamara Mello - Dr. Burke
- Weston Nathanson - Mr. Stein
- Dalia Phillips - Patrice
- Robin Riker - Elizabeth Perry
- Ray Abruzzo - Don Bronson
- Gabriel Bologna - Executive
- William Bumiller - Sam Shearing
- Shontae Saldana - Gang girl
- Shontae Saldana - Carmen
- Michael G. Canaan - CDC Worker
- Larry Cedar - Gordon Edwards
- Rachel Chagall - Renee Edwards
- Donna DuPlantier - Nurse
- Randy J. Goodwin - Dr. Jason Harris
- Taneka Johnson - Rhonda
- Daniel Lujan - John
- Frank Merino - Bad-ass
- Bob Papenbrook - Walt
- Judy Prescott - Maya
- Irene Tsu - Mrs. Fong
- Keone Young - Mr. Fong
- Madeline Zima - Pam
- Monnae Michaell - Phyllis Norton
- Stephanie Venditto - Insurance Company's Attorney
- Paul Ben-Victor - Frank
- Christina Cabot - Amanda
- Adam Cagley - Griffin
- Allie Carieri - Emily
- Brittany Finamore - Olivia
- Carla Renata - Melody
- Candice Rose - Nadine
- Tania Verafield - Heidi
- Marc D. Wilson - Jamar Dobins
- Angelle Brooks - Audrey
- Liz Loza - Joanna
- Jennette McCurdy - Haley Campos
- Paige Moss - Anna
- Jordan Reid - Ashley
- Jeffrey Tedmori - Kid
- Dondré Whitfield - Michael
- Julie Dickens - Nurse Jones
- Bunny Gibson - Meredith's Mother
- Bunny Gibson - Mrs. Monroe
- Alejandro Furth - Det. Darek Mendoza
- Jordan Green - Devil Boy
- Jay Huguley - Donald Murray
- Lyle Kanouse - Max
- Angela Oh - Angelica
- Jill Remez - Dr. Elizabeth Pudlow
- Faith Shin - Keri
- Camille LaChe Smith - Courtney
- Anna Carolina Alvim - Margari
- Sarah Colonna - Nora
- Stuart Damon - Mr. Jennings
- Susan Grace - Miriam Kleinfeld
- Bug Hall - Steve Kelley
- Reamy Hall - Betty
- Holly Hawkins - Patient
- Wendy Johnson - Blind Olive
- Stephen Grove Malloy - Justice Dept. Lawyer
- Patrick J. Adams - Brandon
- Amy Aquino - Willa James
- Cynthia Beckert - Dr. Jane
- Darin Cooper - Dr. Mark Lantana
- Michael Trucco - Zack
- Michael Trucco - Victor
- Kavita Patil - Dr. Ann
- Danielle Rayne - Officer Marj
- Michael B. Silver - Ed Davis
- Darby Stanchfield - Hilary Davis
- Bellamy Young - Erin Berman
- Natalia Baron - Rebecca
- Lance Roberts - 2003-2005
- Rebecca Street - Bridget
- Aria Wallace - Emma Millbrook
- Vanessa Bell Calloway - Melanie Rhodes
- Carrie Dobro - Mrs. Foster
- Bart Johnson - Jake Matousak
- Barry Livingston - Dr. Franco
- Don Luce - Mr. Chavez
- Sundra Oakley - Keats
- Katie Rich - Thelma Durrell
- Hector Luis Bustamante - Officer Wyatt
- Warren Davis - Johnny
- Paul Dillon - Frank the Truck Driver
- Debbie Fan - Gen-ji
- Nichole Hiltz - Katie Burke
- Suzanne Krull - Aileen
- Susan Leslie - Bonnie
- Faruq Tauheed - Timothy
- Sam Trammell - Kiko Ellsworth
- Luna Lauren Velez - Dr. Vanessa Burke
- Leslie Augustine - Russian immigrant patient
- Kate Fuglei - Helen
- Christopher Halsted - Host - Beauty Pageant
- Isabella Hofmann - Maureen O'Connell
- Irene Olga López - Estella Gomez
- Jamie McShane - Immigration official
- Tony Perez - Reuben Gomez
- Jeris Poindexter - Old man / mechanic
- David Shackelford - Truck Driver
- Todd Truley - Salesman
- Irena Violette - Nadia Rodika
- Virginia Williams - Tina Morgan
- Ingrid Sanai Buron - Sharon
- Melanie Hawkins - Ariana Romano
- Krysten Leigh Jones - Amy
- David Lowe - White House P.R.
- Tammi Mac - Carmen
- Rainbow Underhill - Jeri-Lyn Johnson
- D.C. Douglas - Agent Norton
- Jeff Holman - Man
- Anthony Jennings - Train Wreck Victim
- James Kiriyama-Lem - Waiter
- Gonzalo Menendez - Henry Morales
- Shenita Moore - Blood Bank Nurse
- Artie O'Daly - Nurse
- Artie O'Daly - X-Ray Tech
- Senta Moses - Delia Pryor
- Natalija Nogulich - Hillary
- Mario Aguilar Jr. - Rico
- Dorie Barton - Abigail Morton
- LaQuita Cleare - Female Patient
- Cullen Douglas - Lab Tech Abrams
- Martha Millan - Marisol
- Courtenay Taylor - Brandi
- James Frain - Art Gallery Painter
- Carl Gilliard - Principal
- Marcuis Harris - Police Officer
- Thomas Lumberg Jr. - Captain Paul Snow
- Tequan Richmond - Shay Williams
- Lisa Sheridan - Max
- Karen Constantine - Norma-worked w / ROMA BLASI
- Kwesi Boakye - Lavonne
- Toy Connor - Marja
- Mimi Kennedy - Chancellor Eleanor Brubeck
- Yolanda King - Choir Director
- Lynne Maclean - Karen Devane
- Nelson Mashita - Dr. Wong
- Susan Ruttan - Dr. Offenbach
- Jon Spinogatti - Charlie Romick
- Tara Buck - Josie Weaver
- Katie Chonacas - Nikki Gorrell
- Polly Cole - Anita
- Michelle Fabiano - Mrs. Smith
- Kelli Dawn Hancock - Billie
- M.J. Kang - Huan Yuen
- Roma Maffia - Rafael's mother
- Bess Meyer - Carolyn
- Angelique Perrin - Samantha
- Arthur Santiago - Rafael Rodriguez
- Yeardley Smith - Real Estate Agent
- Christina Woods - Janet
- Ryun Yu - Chen
- Adrian Alvarado - Ceasar
- Claudette Nevins - Ava Rey
- Graham Sibley - Elliot Jansen
- Debra Sullivan - Doctor Jane
- Darlena Tejeiro - Yesenia Barrera
- Becky Wahlstrom - Terry Garutso
- Annie Abbott - Dolores
- Pedro Miguel Arce - Bouncer
- Kiko Ellsworth - Carl
- Kiko Ellsworth - Will Manning
- Ezra Buzzington - Bartender
- Kenneth Dolin - Javiar
- Jack Kandel - One Eyed Jack
- Mia Korf - Miko
- Silas Weir Mitchell - Wade
- Asante Jones - Cop at Holding Cell
- Asante Jones - Policeman
- Asante Jones - Officer Dan Hill
- Wells Rosales - Young Arturo Delgado
- Christina Chambers - Sonja Novack
- Raven Goodwin - Tara
- Deidrie Henry - Angela
- Del Hunter-White - Dorie
- Lisa Renee Pitts - Hilda
- Juan Carlos Cantu - Priest
- David Clennon - Judge
- John Diehl - Mr. Lawson
- Ogy Durham - Alicia Barton
- Ptosha Storey - Alice Wilburn
- Brian Catalano - FBI Agent
- Peggy Dunne - Marta Jefferson
- Katie A. Keane - Attractive Doctor
- Miguel Pérez - Dr. Emilio Rodriguez
- Judy Reyes - Jane Lopez
- Forbes Riley - Wendy
- Anna Khaja - ER Receptionist
- Cara Santana - Maria
- Chelsea Smith - Girl
- Rebecca Tilney - Cynthia Reynolds
- Kristen Ariza - Sahar
- Noel Arthur - Kadeem
- Jon Bradford - Paramedic Newton
- Derrick Brenner - Governor's Aid
- Shahine Ezell - Chale
- Gloria Garayua - Jasmine
- Erin Anderson - Nurse Erin
- Erin Anderson - Drew
- Harriet Sansom Harris - Governer Barbara Curtis
- Bob Rumnock - Dr. Jiles
- Mark Edward Smith - Dr. Paul Norling
- Blake Hightower - Hayden
- Heather Kafka - Callan Howe
- Gabriel Olds - Prosecutor Bishop
- Victoria Gabrielle Platt - Dena Borelli
- Alexandra Anthony - Dr. Jody Ziegler
- Jeanette Brox - Sophie Raibly
- David Douglas - Harold
- Brian Hallisay - Dr. George Harmon
- Connie Jackson - Annette
- Erika T. Johnson - Admitting Nurse
- Alexandra Krosney - Francis Raibly
- Adriana Millan - Mother
- Alina Phelan - Mother
- Lisa B. Tharps - Betty
- Madison Bauer - Rowena
- Roshawn Franklin - Chris Jefferys
- Geri Jewell - Holly
- Lorena Mena - Gigi
- J.R. Villarreal - Marcos Garcia
- Michael Welch - Win
- Vince Corazza - Dino Benedetti
- Kate Forster - Mom
- Clyde Kusatsu - Dr. Stan Liem
- Audrey Wasilewski - Marti
- Derrex Brady - Dr. Adrian Burwell
- Claire Coffee - Cassandra Turley
- Freddie DeGrate - Sewer Worker
- Kip Gilman - Haim
- Cameron Hopkin - Chewie Leland
- Charles Hutchins - Mr. Mather
- Natasha Pearce - Latanya
- Dex Elliott Sanders - DeShawn Davis
- Preston Bailey - Dougie Nauls
- David Burr - Stan Ryan
- Brigitta Dau - Angela
- Michael Edwin - Super
- Presciliana Esparolini - Maria Bastante
- Skyler Gisondo - Tommy Nauls
- Tria Katz - Mother
- Savanna Kylie Lewis - Child
- Zena Leigh Logan - Susan
- Kali Majors - Anika Nauls
- Jack McGee - Kris Kringle
- Mario Prado Jr. - Miguel Bastante
- Brandon Ratcliff - Little Boy
- Ronne Troup - Wendy Ryan
- John L. Curtis - Animal Cop
- David Denman - David
- Terrence Hardy Jr. - Ramiro
- La Monde Byrd - SWAT Officer
- Laura Cordova - Paula Dusman
- Amy Davidson - Jamie
- Kathleen Gati - Kathy Mided
- Nick Hoffa - Uniformed Cop
- Kendra C. Johnson - Sierra Atkins
- Mesan Richardson - Bomb Technician
- Esther Scott - Oleta Edwards
- Mik Scriba - Detective
- Michael Yavnielli - SWAT Officer Svatek
- Mariam Vardani - Arianna
- Daniel Dotterer - Circus Performer
- Heidi Fecht - Seela Jobs
- Stacy Hall - Policeman
- Jack Jason - Alan
- James McMann - Hospital Spectator
- Tahmus Rounds - Juggler
- Trevi Williams - Assistant
- Joanna Sanchez - Mrs. Cortez
- Kale Browne - Jonas' Lawyer
- Sergio Enrique - Rescue Worker
- Keith Pillow - ADA John Flynn
- Veronica Sixtos - Marcela Cortez
- Kimberly Stanphill - Eva
- Nafisah Sayyed - Wanda
- R.J. Adams - Dr. Mark Branson
- Keith Oney - Man
- Jamielyn Lippman - Denise
- Whoopi Goldberg
Sara Gilbert interpreta a Charlayne en la serie.
Rosa Blasi interpreta a Dr. Luisa 'Lu' Delgado en la serie.
Jenifer Lewis interpreta a Lana Hawkins en la serie.
Josh Coxx interpreta a Peter Riggs en la serie.
Tamera Mowry-Housley interpreta a Dr. Kayla Thornton en la serie.
Ricky Schroder interpreta a Dr. Dylan West en la serie.
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