- Siobhán McSweeney - Sister Michael
- Leah O'Rourke - Jenny Joyce
- Robbie Williams - Self (archive footage)
- Gary Barlow - Self (archive footage)
- Jason Orange - Self (archive footage)
- Mark Owen - Self (archive footage)
- Howard Donald - Self (archive footage)
- Aoife Hinds - Mae Chung
- Barbara Adair - Sister Declan
- Sophie Robertson - Charlene Kavanagh
- Tracey Lynch - Fionnula
- Niall Cusack - Father Conway
- Diona Doherty - Katya
- Michael Shea - Clive / Artem
- Anthony Boyle - David Donnelly
- Michael McGarry - Ukranian Lad 1
- Amanda Hurwitz - Maeve
- Ciaran Flynn - Ukranian Lad 2
- Terence Keeley - Emmett
- Bronágh Taggart - Nicola
- Jay Duffy - Harry
- Laurie Kynaston - Philip
- Francis Mezza - Dee
- Brenock O'Connor - Jon
- Sean Sloan - Philip's Father
- Nigel O'Neill - Harry's Father
- Judith Roddy - Ms. De Brún
- Ryan McParland - Jonjo
- Chris Robinson - Mike the Manager
- Chris Robinson - Radio Announcer
- Kerri Quinn - Rita
- Julia Dearden - Maureen Malarkey
- Eleanor Methven - Aunt Bridie
- Ardal O'Hanlon - Eammon
- Calam Lynch - John Paul
- Maria Laird - Wee Tina
- Maria Laird - Tina O'Connell
- Antoinette Morelli - Sales Assistant
- Chris Lew Kum Hoi - Kris
- Sophie Brown - Baby Anna
- Bronagh Waugh - Cathy Maguire
- Ciaran Nolan - Radio Dispatcher
- Bill Clinton - Self (Archive Footage)
- Robert Calvert - Jim
- Julian Moore-Cook - Paddy
- Paul Mallon - Dennis
- Conor MacNeill - Hans
- Michael Byers - Officer Lennox
- Serena Terry - Officer Reid
- Darcey McNeeley - Cara
- Liam Neeson - Chief Inspector Byers
- Jessica Reynolds - Wee Deirdre
- Damien Molony - Gabriel
- Kevin McAleer - Uncle Colm
- Kevin McAleer - Colm McCool
- Art Campion - Father Peter
- Amy Huberman - Tara
- Sinéad Keena - Aideen
- Packy Lee - Jordy
- Beccy Henderson - Aisling
- Claire Rafferty - Miss Mooney
- Conleth Hill - Carlos Santini
- Olwen Fouéré - Sheila
- Frankie McCafferty - Jackie
- Paul Reid - Dead Robert / Declan
- Foy Vance - Singer
- Justine Mitchell - Adult Janette
- Tobias Beer - Richard the Surgeon
- Shauna Higgins - Wee Ma Mary
- Martin Quinn - Wee Cousin Rob
- Phillipa Dunne - Geraldine Devlin
- David Ireland - Sean Devlin
- Amelia Crowley - Deirdre Mallon
- Jamie Beamish - Ciaran
- Vanessa Ifediora - Laurie
- Emmett Scanlan - Madstab
- Gerard Jordan - Security Guard
- Fatboy Slim - Self
- Chelsea Clinton - Chelsea Clinton
- Philippa Dunne - Geraldine Devlin
- Bronagh Gallagher - The Commitment
- Sophia Brown - Baby Anna
- Desmond Eastwood - Benny
- Billy Carter - Mailman
Liam Neeson hace el papel de Chief Inspector Byers.
Saoirse-Monica Jackson interpreta a Erin Quinn en la serie.
Louisa Harland interpreta a Orla McCool en la serie.
Nicola Coughlan interpreta a Clare Devlin en la serie.
Jamie Lee O'Donnell hace el papel de Michelle Mallon.
Dylan Llewellyn hace el papel de James Maguire.
Tara Lynne O'Neill interpreta a Ma Mary Quinn en la serie.
Tommy Tiernan interpreta a Da Gerry Quinn en la serie.
Kathy Kiera Clarke interpreta a Aunt Sarah en la serie.
Ian McElhinney hace el papel de Granda Joe.
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