- Charlie Heaton - Gary McCready
- Susan Cookson - Tess Collinson
- Monica Dolan - Maggie Forrest
- Sian Breckin - PC Janet Taylor
- Michael Keogh - PC Dennis Morrisey
- Samuel Roukin - Marcus Payne
- Matt Chapman - Paramedic
- Barry Sloane - Jackie Wray
- Colin Tierney - Chief Supt Gerry Rydell
- Steven Elder - Dr. Patterson
- Charlotte Riley - Lucy Payne
- John Bowe - Dr. Patrick Aspern
- Gary Cargill - Jake McMahon
- John Light - Mark Keane
- Tamzin Merchant - Miranda Aspern
- Rakhee Thakrar - Lab Assistant
- Ian Bartholomew - Timothy Randall
- Di Botcher - Grace
- Raquel Cassidy - Dr. Elizabeth Waring
- Michael Maloney - Malcolm Austin
- Sarah Beck Mather - Chelsea Pilton
- James Boyland - Tony Grimes
- Anna Wilson-Jones - Rosalind Rydell
- Scarlett Rose Patterson - Emily Rydell
- Olivia Popica - Angela Petri
- Gabriela Romanov - Mrs Petri
- Christine Bottomley - Katy Heath
- Oliver Woollford - Kyle Heath
- John Lightbody - Paul Cain
- Rick Warden - Mark Campbell
- Ellie Rooney-West - Hannah Mullen
- Alice Henley - Maddy Phillips
Capítulo disponible en las siguientes plataformas:
