- Brooke Bundy - Joan Smith
- Andy Romano - Lou Bowman
- Lou Antonio - Gordon Krager
- Peter White - Jeremy Jackson
- Robert Pine - Lt. Pete O'Connell
- Julie Adams - Patricia Fairley
- Gordon Pinsent - Frank Fairley
- Norman Alden - Benjamin Marsh
- Robert Hogan - Van Evans
- Mickey Rooney - Kenny O'Malley
- David Soul - Lawrence Merrill III
- Peter Brown - Fred Bowers
- Harrison Ford - Hewett
- Fritz Weaver - Dr. Michael Serling
- John Lasell - Ben Wedlock
- Don 'Red' Barry - Ed Gurney
- Charles Seel - Harry
- Vic Morrow - Steve Harrison
- Andrew Prine - Terry Young
- Linda Marsh - Eleanor Zachary
- Paul Bryar - Lou Fein
- Joseph V. Perry - Leiber
- Lynne Marta - Jody Forbes
- Jack Ging - Corporal Wade Pollock
- Arch Johnson - Sergeant Forbes
- Barney Phillips - Mike Golden
- Barney Phillips - Dr. Golden
- John Beck - Steve Phipps
- Carolyn Jones - Margo
- H.M. Wynant - Lou Kramer
- Bill Erwin - Coroner
- Lillian Bronson - Amy Phipps
- Dabney Coleman - Rick Bessett
- Janice Rule - Thelma Venable
- Warren Parker - Doctor
- Arthur Tovey - Pallbearer (uncredited)
- Ellen Corby - Agnes Oaks
- Jerry Douglas - Stan Palmer
- Gerald S. O'Loughlin - Dominic Lazar
- Chris Robinson - Stan Manders
- Jan-Michael Vincent - Kevin Colter
- Bartlett Robinson - Head of Military Academy
- Forrest Compton - Mr. Colter
- Vera Miles - Carla
- Mike Henry - Heap Canfield
- Rance Howard - Hobbs
- Geoffrey Lewis - Jerry
- Soon-Tek Oh - Au Chau
- Raymond St. Jacques - Jimmy Barlowe
- Nehemiah Persoff - Leo Cussoni
- John Considine - Sylvester
- Bill Quinn - Judge
- Michael Warren - Mr. Gant
- Bob Harks - Doctor (uncredited)
- Quinn Martin
- Dave Grusin
Harrison Ford interpreta a Hewett en la serie.
Mickey Rooney interpreta a Kenny O'Malley en la serie.
Burt Reynolds hace el papel de Det. Lt. Dan August.
Norman Fell interpreta a Sgt. Charles Wilentz en la serie.
Richard Anderson interpreta a Chief George Untermeyer en la serie.
Ned Romero hace el papel de Sgt. Joe Rivera.
Ena Hartman interpreta a Katy Grant en la serie.
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