- Barbara Rhoades - Lt. Lynch
- H.B. Haggerty - Captain Gourgeous
- Kimberly Beck - Stella
- Bryan Dattilo - Little Boy
- Dick Van Patten - Howard
- Michael Callan - TV Station Manager
- Simone Griffeth - Mrs. Alexandria Morgan
- Vic Tayback - Mo Scmidt
- Tracy Scoggins - Joy
- Benson Fong - Harry Woo
- Rue McClanahan - Angie
- Frank Ashmore - Ward Pressman
- George Clooney - Skip Woods
- Joyce Van Patten - Sally
- Bo Svenson - Chuck Dobson
- Michael Gregory - Detective
- Gene Barry - Nicholas Roland
- Carol Kane - Iris Buckles
- Natalie Schafer - Leonna Felspar
- Sharon Acker - Olivia Sinclair
- Anne Francis - Sister Elizabeth / Laura Jennings
- Mark Shera - Ted Bennett / Swanson
- Paul Koslo - Maggot
- Jason Bernard - Judge
- Jed Allan - Dr. Sloan
- Kim Darby - Jenny Fenwick
- David Wayne - Jennings Hyde
- Keye Luke - Jimmy
- Paul Mantee - Bailey
- Pat Carroll - Martha
- Andrew Prine - Cecil Beckman
- George Kirby - Manny
- Charles Aidman - Randalph Loehrman
- Gary Crosby - Eddie
- Nicholas Pryor - Nick Floyd
- Daryl Anderson - Mickey
- Cindy Morgan - Dana Byers
- Robert Pine - Trenner
- James Saito - Chinese Henchman
- Louise Mandrell - Bobby Joe
- Al Ruscio - Cinco
- Pat Harrington, Jr. - Chick Parish
- Christopher Allport - Endicott
- Lou Wagner - Tommy Shea
- Peter Hobbs - Father Ryan
- Murray MacLeod - Elmo
- Michael Lembeck - Dr. Andy Farr
- France Nuyen - Lily
- Jane Kaczmarek - Julie Floyd
- LaGena Hart - Janice
- Bette Ford - Mrs. Bishop
- Sharon Spelman - Mrs. Murdoch
- Peter Brown - Bill Merrick
- Harvey Jason - Greg Zackinski
- Darleen Carr - Donna Burns
- Marta DuBois - Suzanne / Marilyn
- Isabel Sanford - Car Rental Receptionist
- DeAnna Robbins - Susan Whatley
- Dave Shelley - Floyd
- Ivor Barry - Admiral
- Stan Ivar - Detective
- Leah Ayres - Elaine Mulligan
- Clyde Kusatsu - Hye Sook Yung
- Sorrell Booke - Bernard 'Bernie' Sinclair
- Paul Comi - Mr. Tyler
- Dorothy Lamour - Rosie
- Vera Miles - Georgina Burton
- Bo Hopkins - Lowell
- William Bogert - Morton Felspar
- Gary Graham - Judd Downing
- Dick O'Neill - 'Tip' Maloney
- Diane McBain - Tattooist
- Michael Laskin - Steve
- Peter Mark Richman - Dr. Donald Rafelman
- Beverly Garland - Liz Wellington
- Lloyd Bochner - Vincent Mulligan
- Joseph Campanella - Bart Simian
- Herb Edelman - Inspector Rouletti
- Don Galloway - Derek
- Paul Lambert - Phil Martone
- Doug McClure - J.D. Pennington
- Ed Lauter - Lanslow
- Nancy Walker - Mrs. Wrench
- John Harkins - Henry Clayborn
- Barbara Babcock - Ellen
- Morey Amsterdam - Mr. Margus
- Oliver Clark - Jason Santo
- Stephen Nichols - Croiser
- Jayne Meadows - Vi
- Mary Ellen Trainor - Connie Olsen
- Gloria LeRoy - Aida
- Michael D. Roberts - Damon
- David Hedison - Ed Galvin
- Craig Littler - Nick
- Audrey Landers - Dianne Bennett
- Norman Fell - Inspector Peyton
- Jonathan Banks - Vice Squad Captain Hawkins
- Cyd Charisse - Barbara Carlisle
- Art Hindle - Paul Burns
- Susan Tolsky - Reverend
- Barbara Bosson - Riza's Ex-wife
- Michael Constantine - Police Inspector
- Tom Poston - Fiedler
- Lew Horn - Dr. Benolli - Berkeley Film School
- Scott Devenney - Alan
- Regina Waldon - Widow
- Bob Coffey - Tony
- John X. Heart - Stanford Rooter
- Ray K. Goman - Sergeant
- Sheldon Feldner - Cabbie
- Robert F. Hoy - Sid - Projectionist
- Eddie Ryder - Mel
- José Flores - Attendant
- Mitch Brown - Valet
- Michel Voletti - Waiter
- Shannon Wilcox - Valerie Mason
- Gerry Gibson - Father Carroll
- Stanley Brock - Jake
- Victor Rendina - Emilio
- Teddy Wilson - Ernie
- Nicholas Hammond - James Daniel Parrish
- Anne Kerry Ford - Liz
- Alain Saint-Alix - Pierre
- Bud Davis - Businessman
- Terence Monk - Proprietor
- Steve Dougherty - Ambulance Attendant
- Tom Bower - Trumble
- Kiva Lawrence - Businesswoman
- Ed Bakey - Earl Stanton
- Susan Bjurman - Barbara Dobson
- Gary Pagett - Clark County Sheriff
- Kenneth Tigar - Mr. Delaney
- Kenneth Tigar - Richard Morris
- Justin Lord - Jenson
- Wilfredo Hernández - Chavez
- Fritzi Burr - Mabel
- Chino 'Fats' Williams - Fats
- Belinda Montgomery - Diane
- Belinda Montgomery - Kelly Aspen
- Rigg Kennedy - Rexford
- Kurt Smildsin - Ralph
- Terri Treas - Camille Montgomery
- Terri Treas - Andrea
- Philip Casnoff - Gino Ferrari
- Mark Costello - Nolan
- Eugene Choy - Jimmy
- Aaron Seville - Lot Attendant
- Douglas Hume - Fork Operator
- Steve Carlson - Frank Riley
- Hoke Howell - Schafer
- Fred Carney - Mr. Pancrest
- Lewis Dauber - Clerk
- Rhodie Cogan - Woman
- Joshua Bryant - Colonel Glendon
- Tony Goodstone - Arms Buyer
- David Banks - Turner
- Jeff Osterhage - Brad Pennington
- Marcelo Tubert - Deputy
- Joe Maross - Herb Spencer
- Tom Hallick - Renner
- Bill Zuckert - Custodian
- S. Pearl Sharp - News Reporter
- Kathy Shower - Stewardess
- Don Maxwell - Chauffeur
- John J. Flynn Jr. - Stoddard
- Thomas J. Reilly - Client
- Thomas J. Reilly - Passenger
- Thomas J. Reilly - Golfer
- Dominic Hoffman - Vice Officer
- Bernadette Williams - Mrs. Stone
- Bernadette Williams - Mrs. Riley
- Al Wyatt Jr. - Contra
- Jim Steck - Hard Hat
- Gary Pettinger - Hard Hat
- Philip Brown - Ken
- Amanda Horan Kennedy - Gina
- John Considine - Nick / Larry Simpson
- Richard Roat - Phillip Harmon
- Doug Hale - Lt. Connelly
- Mort Sertner - Dorsey
- Joan Shawlee - Manager
- Sig Frohlich - Bellhop
- Camilla More - Beautiful Girl
- Robin Strand - Brian Selkirk
- Jeff Eagle - Officer
- Jeff Eagle - Policeman
- Lydia Lei - Allison
- Buck Taylor - Blake
- Dennis Hayden - Renco
- Jean-Paul Vignon - Maitre d'
- Ed McCready - Don
- John Petlock - Hotel Clerk
- Alice Nunn - Mrs. De Curtis
- Bill Capizzi - Walsh
- Brit Lind - Betty Colton
- Lori Michaels - Secretary
- Lori Michaels - Woman
- Vernon Weddle - Hearing Officer
- John Mahon - Lt. Doyle
- John Mahon - Zach
- Stephen Tobolowsky - Hotel Clerk
- Bucklind Beery - Jailer
- Robert Hanley - Julie - Pickpocket
- Robert Hanley - Lt. Sportelli
- Robert Hanley - Walker
- Robert Hanley - Inspector Walker
- Tommy Madden - Mo Young
- Marshall R. Teague - Scott Byers
- Robert Lussier - Mr. Ray
- Naomi Stevens - Madam June Moon
- Andre Rosey Brown - Massive Man
- Magic Schwarz - The Bazooka
- Ted Noose - Security Guard
- James R. Parkes - Bomb Squad Officer
- Peter White - Russ Cramer
- Lou Felder - Mike Meyerson
- Julie Hayek - Sandy
- Floyd Levine - Cecil
- Stuart Nelson - Waiter
- Michael Kearns - Pro
- Michael Francis Kelly - Stan
- Jerry Jones - Porter
- J. Víctor López - Groundskeeper
- Della Reese - Nurse Flood
- Della Reese - Mrs. Flood
- Carolyn Ann Clark - Claudia
- Barbara Pariot - Tour Guide
- Ken Hill - Security Guard
- Steve Fogel - Man In Tag
- Steve Fogel - Pickpocket
- Steve Fogel - Moviegoer
- Elven Havard - Police Officer
- Joan Benedict Steiger - MC
- Lori Lethin - Lisa
- Andrew Masset - Garret Hollander
- Barbara Cason - Paula
- Joe Flood - Cabbie
- Joe Flood - MacGruder
- Robin Bach - Guide
- Ja'net DuBois - Idee
- Ed Griffith - Dale Bradford
- Terrence Beasor - Referee - Rev. Anderson
- Tim Choate - Joe Cusack
- Deena Freeman - Claire
- Donald Hayes - Guard
- Jeffrey Lampert - Melvin
- Muriel Minot - Woman
- Bruno Marcotulli - Guard
- Andrea Aal - Secretary
- Angus Duncan - Dr. Morgan
- Debra Dusay - Nurse
- Patrick Wright - Officer
- Edward Bell - Jonathan Cross
- Audre Johnston - Secretary
- Tony O'Neil - Carney
- Peg Shirley - Mabel
- Danny Kwan - Kai Ling
- Richard Epcar - Officer
- James McEachin - Brigga
- Doctor Hayes - Security Guard
- Judy Kain - Green Cabbie
- Ernest Harada - Blue Cabbie
- Ed Hooks - Pete Farmer
- Ed Hooks - Petey
- Burt Marshall - Red Cabbie
- Branscombe Richmond - Jack Tremaine
- Branscombe Richmond - Gunman
- Andrea Barber - Sherry
- Jeff Calhoun - Deputy Pippin
- Jay Ingram - Anglin
- Leigh McCloskey - Bob Byers
- Sally Julian - Patty Chapman
- Jerry Prell - Phil Chapman
- Rif Hutton - Coroner
- Trent Dolan - Customer
- Clive Rosengren - Knight
- James Ingersoll - Joey Riza
- Kay Kimler - Rookie
- Billy Beck - Dusty
- Vic Polizos - Angelo Ferrino
- Patricia Ayame Thomson - Allison
- Patricia Ayame Thomson - Allison Lee
- Ty Henderson - Newspaper Photographer
- Gary Ellenberg - Cable Car Passenger
- Bert Rosario - Eddy
- John Mansfield - Jim Wheeler
- Pepper Martin - Inspector Stockwell
- Ruben Moreno - Waiter
- Ellen Tobie - Julia
- Phyllis Davis - Brenda West
- Dan Gilvezan - Cop
- Robert Curtin - Craig Hooks
- Eric Poppick - Dewey Littlefield
- Diana Bellamy - Mrs. Littlefield
- Jim Ishida - Dr. Goto
- Suzanne von Schaack - Marcia
- Martin Rabbett - Duncan
- Ed Markmann - Marcellus
- John Baskin
- George Schenck
- Frank Cardea
- Mark Snow
Naomi Stevens interpreta a Madam June Moon en la serie.
Jonathan Banks hace el papel de Vice Squad Captain Hawkins.
Stephen Tobolowsky interpreta a Hotel Clerk en la serie.
Joan Shawlee hace el papel de Manager.
Kimberly Beck hace el papel de Stella.
George Clooney interpreta a Skip Woods en la serie.
Jack Warden hace el papel de Harry Fox.
John Rubinstein hace el papel de Harrison Fox.
Penny Peyser hace el papel de Cindy Fox.
Robby Kiger interpreta a Josh Fox en la serie.
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