- Kieran O'Brien - Mark Fitzgerald
- Kieran O'Brien - Mark
- Robert Cavanah - Temple
- Colin Tierney - Harriman
- Barbara Flynn - Judith Fitzgerald
- Barbara Flynn - Judith
- Christopher Eccleston - David Bilborough
- Christopher Eccleston - Bilborough
- Adrian Dunbar - Kelly
- Andrew Tiernan - Sean
- Kika Markham - Ann Appleby
- Tim Barlow - Judith's Father
- Gavin Muir - Cormack
- Marianne Jean-Baptiste - Marcia Reid
- Ron Donachie - Barney
- Anthony Lewis - Steven Nash
- Jeffrey Robert - Head of Psychology
- Andy Devine - Guard on Train
- Ron Meadows - Roberts
- Kerry Shale - Scene of Crime Expert
- Vincent Davies - Taxi Driver
- Peter Faulkner - Mike
- Kathy Jamieson - Jo
- Julie Westwood - PR Woman
- Philippa Howell - Dr Turner
- Alan David - Hanrahan
- Tony Xu - Dr Soraya
- Sunetra Sarker - Receptionist
- Seamus O'Neill - D.C. Jones
- Renny Krupinski - Voice Expert
- Danny Davies - Ticket Inspector
- Alan Partington - Mr Hobbs
- Romy Baskerville - Irene Hobbs
- Daryl Fishwick - Mrs Forbes
- John Grillo - Simon Appleby
- David Crellin - Quinlan
- Diane Adderley - Mrs Royle
- Nicholas Woodeson - Hennessy
- Fine Time Fontayne - Bookie
- Nelson Fletcher - Custody Sergeant
- Louise Downie - Jacqui Appleby
- Don Henderson - Hennessy Senior
- Amanda Loy-Ellis - Girl on Train
- Ruth Holden - Lady on Bus
- Margo Stanley - Lady on Bus
- Reginald Stewart - Neighbour
- Sarah Keyzer - Nikki Price
- Eve Bland - Mrs Cormack
- Terry Gilligan - Lenny Lyon
- Ian Mercer - D.C. Giggs
- Beryl Reid - Fitz's Mum
- David Haig - Graham
- James Quinn - Doorman
- Rose English - Pathologist
- Kathryn Hunt - Mrs Rivers
- Glenn Cunningham - Mr Rivers
- Al T. Kossy - Expert in Pub
- Owen Brenman - Haig
- Susan Lynch - Tina
- Parvez Qadir - Petrol Station Attendant
- Tamsin Heatley - Woman in House
- Susan Vidler - Sammy
- Patti Love - Mrs Brien
- Steve Halliwell - Fire Officer
- Linda Henry - Mrs Perry
- Geoffrey Hutchings - Pathologist
- Tim Healy - Mr Lang
- Christopher Fulford - Nigel Cassidy
- John Vine - Lindsay
- Trevyn McDowell - Leslie
- Amelia Bullmore - Catriona Bilborough
- Stan Finni - Sergeant Smith
- Ruth Sheen - Jean McIlvanney
- Ruth Sheen - Jean McIIvanney
- John Graham Davies - Francis Bates
- Frances Tomelty - Mrs. Lang
- Mike Kelly - Peter Lloyd
- Badi Uzzaman - Shahid Ali
- Shango Baku - Gregson
- David Calder - Michael Harvey
- David Calder - Father Michael Harvey
- Rebecca Clay - Counter Clerk
- Ken Christiansen - 2nd Skinhead
- John Pickles - Neighbour
- Peter Clifford - Doctor
- Rosa Roberts - Householder
- Glyn Grain - Professor Nolan
- Kim Vithana - Razia Ali
- Tony Barton - Builder
- Tony Peers - Man in Albie's Street
- Frankie Jordan - First Woman
- Sandra Gough - Second Woman
- Gemma Phoenix - Ruth
- June Broughton - Woman Shopper
- Philip Childs - Radio Operator
- Robert Carlyle - Albie
- John Henshaw - Quarry Foreman
- David Holt - Hospital Administrator
- Beth Goddard - Clare Moody
- Tracy Gillman - Jill
- Johnny Leeze - 1st Manchester Utd Fan
- Kevin Quarmby - 1st Steward
- Samia Longchambon - Rosie
- Doc O'Brien - Bus Driver
- Andy Abrahams - Police Officer
- Samantha Morton - Joanne Barnes
- Darren Tighe - Dean Saunders
- Roger Sloman - Mr Barnes
- Ellie Haddington - Mrs Barnes
- Lottie Ward - Nurse
- Jeffrey Longmore - Local PC
- Nicholas Blane - Father O'Ryan
- James Fleet - Michael Trant
- Maureen O'Brien - Virginia Trant
- Jim Carter - Kenneth Trant
- Cherith Mellor - Norma Trant
- Kelvin Fletcher - Boy
- Emma Cunniffe - Sarah Jennings
- Ina Clough - Elderly Dancer
- John McArdle - Tom Carter
- Marian McLoughlin - Catherine Carter
- Gerard O'Hare - O'Rourke
- Stefan Escreet - Doctor
- Tony Rohr - Molloy
- John Middleton - Jed Robins
- Claire Hackett - Deborah Wiley
- Andrew Readman - Andrew Wiley
- Joe Simpson - Taxi Inspector
- Alexander Newland - Marvin Malcolm
- Julie Saunders - Bev Malcolm
- Fiona Allen - House Owner
- Graham Aggrey - Floyd Malcolm
- Rachel Davies - Mrs Malcolm
- Ewen Cummins - Wilson
- Angela Wynter - Barbara Charles
- Darren Brown - Priest
- Rodney Litchfield - Taxi Driver
- Edward Peel - Chief Super
- Edward Peel - Chief Superintendent
- Dan Armour - Man at Cashpoint
- Owen Aaronovitch - Charnock
- Barbara Young - Helen McIIvanney
- Paul Copley - Pathologist
- Sharon Percy - Joyce Watkins
- Stephen Tomlin - DNA Expert
- Andrew Knott - Joe Harvey
- Andrew Whyment - Matthew Harvey
- Isobel Middleton - Catriona Bilborough
- Irene Marot - Paula
- Mark Lambert - David Harvey
- Polly Hemingway - Denise Fletcher
- Brid Brennan - Maggie Harvey
- Aisling O'Sullivan - Aileen
- Jackie Downey - Mrs Franklin
- Steve Money - Cutter
- Paul Barber - Ian McVerry
- John Simm - William 'Bill' Preece
- Liam Cunningham - Stuart Grady
- Annette Ekblom - Diane Nash
- John Langford - Brian Nash
- Jim Whelan - Foreman
- Dave Hill - Mr Franklin
- Katherine Dow Blyton - Doctor
- Elizabeth Estensen - Reenie Wise
- Kenneth Gilbert - Father
- Larry Waller - Dave
- Ian Curtis - John Branaghan
- Bridget Hodson - Carol Barker
- Will Knightley - Pathologist
- Jane Lowe - Landlady
- Peter Lorenzelli - Dog Owner
- Clive Russell - Danny
- Emily Joyce - Janice
- Rosemary Martin - Irene Jackson
- Hetta Charnley - Maureen Kiernan
- Fleur Bennett - Nena
- Iain Mitchell - Vice Chancellor
- Danny Green - Waiter
- Wil Johnson - Skelton
- Paul Abbott
- Gub Neal
- Sally Head
- Hilary Bevan Jones
Danny Cunningham hace el papel de Bob.
Samantha Morton interpreta a Joanne Barnes en la serie.
Kieran O'Brien interpreta a Mark en la serie.
Christopher Eccleston interpreta a Bilborough en la serie.
Robbie Coltrane hace el papel de Edward 'Fitz' Fitzgerald.
Geraldine Somerville interpreta a Jane 'Panhandle' Penhaligon en la serie.
Barbara Flynn hace el papel de Judith Fitzgerald.
Ricky Tomlinson hace el papel de Wise.
Robert Cavanah hace el papel de Temple.
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