- Doris Speed - Annie Walker
- Christopher Harper - Nathan Curtis
- Debbie Rush - Anna Windass
- Victoria Ekanoye - Angie Appleton
- Barbara Knox - Rita Sullivan
- Jack P. Shepherd - David Platt
- William Tarmey - Jack Duckworth
- Chris Gascoyne - Peter Barlow
- Sue Cleaver - Eileen Grimshaw
- Michael Le Vell - Kevin Webster
- Samia Longchambon - Maria Connor
- David Neilson - Roy Cropper
- Sue Nicholls - Audrey Roberts
- Lorna Laidlaw - Aggie Bailey
- Trevor Michael Georges - Ed Bailey
- Ruxandra Porojnicu - Alina Pop
- Violet Carson - Ena Sharples
- Bernard Youens - Stan Ogden
- Millie Gibson - Kelly Neelan
- Jude Riordan - Sam Blakeman
- Vicky Binns - Molly Compton/Molly Dobbs
- Gaynor Faye - Judy Mallett
- Sally Dynevor - Sally Metcalfe
- Helen Worth - Gail Platt
- Shelley King - Yasmeen Metcalfe
- Ian Bartholomew - Geoff Metcalfe
- Jimmi Harkishin - Dev Alahan
- Mikey North - Gary Windass
- Beverley Callard - Liz McDonald
- Anne Kirkbride - Deirdre Barlow
- Katherine Kelly - Becky Granger / Becky McDonald
- Jean Alexander - Hilda Ogden
- Jean Alexander - Mrs. Webb
- Kate Ford - Tracy Barlow / Tracy McDonald / Tracy Preston
- Tina O'Brien - Sarah Platt
- Tina O'Brien - Sarah Barlow
- Tina O'Brien - Sarah Grimshaw
- Patricia Phoenix - Elsie Tanner
- Patricia Phoenix - Elsie Howard
- Jennie McAlpine - Fiz Stape
- Jennie McAlpine - Fiz Brown
- Julie Hesmondhalgh - Hayley Patterson / Hayley Cropper
- Betty Driver - Betty Williams
- Betty Driver - Betty Turpin
- Antony Cotton - Sean Tully
- Georgia May Foote - Katy Armstrong
- Sally Carman - Abi Franklin
- Sally Carman - Abi Webster
- Jack Watson - Bill Gregory
- Johnny Briggs - Mike Baldwin
- Ian McKellen - Mel Hutchwright
- Natalie Gumede - Kirsty Soames
- Bruce Jones - Les Battersby
- Michelle Keegan - Tina McIntyre
- Malcolm Hebden - Norris Cole
- Steven Arnold - Ashley Peacock
- Bryan Mosley - Alf Roberts
- Ellie Leach - Faye Windass
- Craig Charles - Lloyd Mullaney
- Kym Marsh - Michelle Connor
- Sasha Behar - Maya Sharma
- Sam Aston - Chesney Brown
- Bruno Langley - Todd Grimshaw
- Oscar Hartley - Simon Richards
- Jacqueline Pirie - Linda Sykes / Linda Baldwin
- Marc Baylis - Rob Donovan
- Naomi Radcliffe - Alison Wakefield / Alison Webster
- Stephen Billington - Greg Kelly
- Andrew Whyment - Kirk Sutherland
- Georgia Taylor - Toyah Battersby
- Georgia Taylor - Toyah Habeeb
- Tracy Shaw - Maxine Heavey / Maxine Peacock
- Alison King - Carla Connor / Carla Barlow / Carla Gordon
- Maggie Jones - Blanche Hunt
- Stephanie Cole - Sylvia Goodwin
- Brooke Vincent - Sophie Webster
- Patti Clare - Mary Taylor / Mary Cole
- Patti Clare - Mary Taylor
- Denise Welch - Natalie Barnes
- Suranne Jones - Karen McDonald / Karen Phillips
- Gray O'Brien - Tony Gordon
- John Savident - Fred Elliott
- Bill Ward - Charlie Stubbs
- Rupert Hill - Jamie Baldwin
- Paul Fox - Mark Redman
- Robert James-Collier - Liam Connor
- Christopher Quinten - Brian Tilsley
- Peter Dudley - Bert Tilsley
- Tracie Bennett - Sharon Bentley
- Tracie Bennett - Sharon Gaskell
- Lynne Perrie - Ivy Brennan / Ivy Tilsley
- Amanda Barrie - Alma Baldwin / Alma Sedgewick / Alma Halliwell
- Shobna Gulati - Sunita Alahan / Sunita Parekh
- Bradley Walsh - Danny Baldwin
- Andrew Lancel - Frank Foster
- Chris Fountain - Tommy Duckworth
- Nigel Havers - Lewis Archer
- Daniel Brocklebank - Billy Mayhew
- Sally Ann Matthews - Jenny Bradley / Jenny Connor
- Richard Hawley - Johnny Connor
- Julie Goodyear - Bet Lynch / Bet Gilroy
- Roy Barraclough - Alec Gilroy
- Peter Ash - Paul Foreman
- Paula Wilcox - Elaine Jones
- Mark Frost - Ray Crosby
- Adam Rickitt - Nick Tilsley
- Wendi Peters - Cilla Battersby-Brown / Cilla Brown
- Reece Dinsdale - Joe McIntyre
- Brian Capron - Richard Hillman
- Richard Fleeshman - Craig Harris
- Mark Eden - Alan Bradley
- Lisa Lewis - Shirley Armitage
- Peter Adamson - Len Fairclough
- Arthur Lowe - Leonard Swindley
- Jack Howarth - Albert Tatlock
- Samuel Robertson - Adam Barlow
- Charlotte Jordan - Daisy Midgeley
- Jane Hazlegrove - Bernie Winter
- Jane Hazlegrove - Sue Clayton
- Vinta Morgan - Ronnie Bailey
- Susan Jameson - Myra Booth / Myra Dickinson
- Doreen Keogh - Concepta Hewitt / Concepta Riley
- Ivan Beavis - Harry Hewitt
- Jennifer Moss - Lucille Hewitt
- Sue Jenkins - Gloria Todd
- Catherine Tyldesley - Eva Price
- Alexandra Mardell - Emma Brooker
- William Flanagan - Joseph Brown
- Maureen Lipman - Evelyn Plummer
- Betty Alberge - Florrie Lindley
- Margot Bryant - Minnie Caldwell
- Sandra Gough - Irma Ogden
- Sandra Gough - Irma Barlow
- Jamie Kenna - Phill Whittaker
- Sue Devaney - Debbie Webster
- Joe Duttine - Tim Metcalfe
- Joe Duttine - D.S. Carr
- Lawrence Mullin - Steve Fisher
- Madge Hindle - Renee Bradshaw/Roberts
- Sarah Lancashire - Raquel Watts
- Sarah Lancashire - Raquel Wolstenhulme / Raquel Watts
- Barbara Young - Doreen Fenwick
- Barbara Young - Barbara Platt
- Barbara Young - Mrs. Stockwell
- Ian Donnelly - Sign Writer
- Renee Montemayor - Doctor
- Susan Twist - Lydia Hartman
- William Rush - Ian
- William Ash - Spike
- Steven Blakeley - Office Manager
- Phil Taylor - Disco Dave
- Ashley Campbell - D.C. Wiley
- Jennifer Wilson - Mrs. Bradbury
- Nicola Thorp - Nicola Rubinstein
- Jade Greyul - Stacey
- Martin Shaw - Robert Croft
- Noel Howlett - Mr Tabley
- Patrick Newell - Mr. Mullins
- Doreen Mantle - Joy Fishwick
- Anita Carey - Joyce Smedley
- Anita Carey - Brenda Summers
- Sherrie Hewson - Maureen Holdsworth
- Frank Mills - Billy Williams
- Malcolm Terris - Eric Firman
- Maria Charles - Lena Thistlewood
- Victoria Myers - Detective Sergeant Swain
- John Junkin - Bill Fielding
- Barry Jackson - Mr. Garfield
- Andrew Sachs - Ramsay Clegg
- Sharon Duce - Paula Carp
- Michael Byrne - Ted Page
- Jennifer James - Geena Gregory
- Terence Harvey - John Harris
- Michael Jayston - Judge
- Greg Patmore - Jonny Smith
- Greg Patmore - Biker
- Georgine Anderson - Mrs. Fielding
- Georgine Anderson - Eunice Watts
- Lesley Manville - Jill Mason
- Gerald Sim - Ted Farrell
- Brian Wilde - Sam Ross
- Elisabeth Sladen - Anita Reynolds
- John Bailey - Doctor Grant
- Christian Rodska - Mr. Newton
- George Waring - Arnold Swain
- Anne Reid - Valerie Barlow
- Anne Reid - Valerie Tatlock
- Alan Curtis - Mr. Thornley
- Ballard Berkeley - Colonel Cantrill
- Michael Bilton - Tom Hedley
- Jimmy Gardner - Tiny Hargreaves
- Christopher Ravenscroft - Police Sergeant
- Paul Angelis - Brian Bowes
- Peter Baldwin - Derek Wilton
- Donald Gee - Roger Crompton
- David Michaels - Jon Welch
- Kenneth Cope - Jed Stone
- Norman Bird - Frank Jackson
- Eve Pearce - Miss Franklin
- Margery Mason - May Schofield
- John Comer - Mr. Birtles
- Rhoda Lewis - Miss Welch
- Kathy Staff - Vera Hopkins
- Kathy Staff - Woman in Audience (uncredited)
- Richard Davies - Idris Hopkins
- Michael Gover - Edward Pollard
- Richard Lynn
- Brett Fallis
- Ian Barber
- Nickie Lister
- Abe Juckes
- Tim Royle
- Stephen Russell
- Daran Little
- John Fay
- Chris Fewtrell
- Jayne Hollinson
- Jan McVerry
- Phil Collinson
- Bill Podmore
- Steve November
- Kieran Roberts
- Antony Wood
- Carolyn Reynolds
Ian McKellen interpreta a Mel Hutchwright en la serie.
Stephen Billington hace el papel de Greg Kelly.
Michael Byrne interpreta a Ted Page en la serie.
William Roache hace el papel de Ken Barlow.
Capítulo disponible en las siguientes plataformas:
