- Robert Stephens - Paddy Riordan
- Susan Kohner - Rena Covic
- Jonathan Bolt - Bert
- John Cassavetes - Lloyd Sullivan
- Katherine Crawford - Marty Maddow
- Robert Ellenstein - Maddow
- Noreen Corcoran - Donna
- Leslie Nielsen - Prof. Paul Stafford
- Yale Summers - Fraternity President
- Peter Fonda - Everett Partridge
- Michael Parks - Benny Dickson
- Sondra Blake - Bernice
- Aron Kincaid - George
- Hedley Mattingly - Holman
- Philip Ober - Partridge
- Michael Constantine - Nick
- Robert Foulk - Otto
- Barbara Harris - Sophie Kannakos
- Berkeley Harris - Ron Atkins
- William Shatner - Tom Ericson
- Gene Raymond - Matt Bellamy
- Denver Pyle - Sam Riddle
- Maggie Pierce - Jean Curtis
- Pitt Herbert - Whittaker
- Eve McVeagh - Bellamy's Assistant
- Vincent Cobb - Hank
- Suzanne Pleshette - Lori Moore
- Jeanne Cooper - Margaret Dellafield
- Nancy Olson - Jessica Landon
- Forrest Tucker - Major Don Landon
- Jim McMullan - Peter Walker
- Norma Crane - Harriet Cody
- George Segal - Andre
- Greg Morris - Dr. Bledsoe
- Wendell Corey - Professor Jonathan Kobitz
- Don Gordon - Mario Saccone
- Jacqueline Scott - Irene Kobitz
- Joseph Walsh - Pvt. Lennie Schwartz
- Rip Torn - Donald Burrows
- Leslie Parrish - Joyce Ruskin
- Lisabeth Hush - Stephanie Burrows
- Kip King - Bunky
- Ed Nelson - Deke Allison
- Tim Conway - The Young Man
- Chris Robinson - Jim Wilson
- Herb Vigran - Manny
- Russ Tamblyn - Hal Langley
- Mariette Hartley - Evelyn Crown
- David Wayne - Dr. James Crown
- Stuart Margolin - Bob Brodie
- George Voskovec - Prof. Thielman
- Joyce Bulifant - Ellen Dalton
- Jack Laird
Philip Ober hace el papel de Partridge.
Robert Ellenstein interpreta a Maddow en la serie.
William Shatner interpreta a Tom Ericson en la serie.
Robert Foulk hace el papel de Otto.
Michael Parks hace el papel de Benny Dickson.
Eve McVeagh interpreta a Bellamy's Assistant en la serie.
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