- Nicola Correia Damude - Maryse Lightwood
- Alan van Sprang - Valentine Morgenstern
- Maxim Roy - Jocelyn Fray
- Shailene Garnett - Maureen
- Curtis Morgan - Pangborn
- David Castro - Raphael Santiago
- Jon Cor - Hodge Starkweather
- Kaitlyn Leeb - Camille Belcourt
- Jade Hassouné - Meliorn
- Ari Cohen - Theo
- Paulino Nunes - Robert Lightwood
- Susanna Fournier - Young Jocelyn
- Owen Roth - Young Valentine
- Joel Labelle - Alaric
- Stephen R. Hart - Brother Jeremiah
- Stephen Huszar - Brad
- Jessica Matten - Maria
- Nick Sagar - Victor Aldertree
- Joanne Jansen - Gretel
- Stephanie Belding - Dr. Iris Rouse
- Nykeem Provo - Young Luke Garroway
- Jack Fulton - Maxwell "Max" Lightwood
- Farah Merani - Sister Magdalenda
- Vanessa Matsui - Dorothea "Dot" Rollins
- Michelle Argyris - Kaelie
- Christina Cox - Elaine Lewis
- Alec Stockwell - Ithuriel
- Michael Cram - Ned Fisk
- Jenny Raven - Leigh
- Lisa Berry - Cleophas Garroway
- Lisa Berry - Cleophas Garroway (uncredited)
- Romy Weltman - Teen Isabelle Lightwood
- Vicki Kim - Anna
- Will Tudor - Sebastian Verlac
- Sarah Hyland - Seelie Queen
- Stephanie Bennett - Lydia Branwell
- Lola Flanery - Seelie Queen
- Holly Deveaux - Rebecca Lewis
- Tomaso Sanelli - Young Jace
- Lisa Marcos - Captain Susanna Vargas
- Chai Hansen - Jordan Kyle
- Jesse Camacho - Leo
- Jelena Savic - Czech DJ
- Kyana Teresa - Lanaia
- Ana Maria Mallinos - Young Isabelle
- Adam J. Harrington - Michael Wayland
- Mimi Kuzyk - Imogen Herondale
- Raymond Ablack - Raj
- Adam Kenneth Wilson - Ragnor Fell
- Alexander Eling - Teen Alec (as Alex Eling)
- Steve Byers - Underhill
- Kimberly-Sue Murray - Seelie Queen Amara
- Sydney Ozerov-Meyer - Helen Blackthorn
- Joe Lazarov
- Ben Hernandez Bray
- Kelly Makin
- Matthew Hastings
- Oz Scott
- McG
- Zac Hug
- Allison Rymer
- Peter Binswanger
- Cassandra Clare
- Jon Comerford
- Lisa Parasyn
- Chris Hatcher
- Michael Lynne
- Michael Reisz
- Greg Copeland
- Ruelle
- Christian T. Cooke
- Alex Bullick
- J.R. Fountain
- Kevin Banks
- Jack Wall
Katherine McNamara interpreta a Clary Fray en la serie.
Dominic Sherwood interpreta a Jace Wayland en la serie.
Alberto Rosende interpreta a Simon Lewis en la serie.
Matthew Daddario hace el papel de Alec Lightwood.
Harry Shum Jr. hace el papel de Magnus Bane.
Anna Hopkins interpreta a Lilith en la serie.
Emeraude Toubia interpreta a Izzy Lightwood en la serie.
Isaiah Mustafa interpreta a Luke Garroway en la serie.
Alisha Wainwright hace el papel de Maia Roberts.
Capítulo disponible en las siguientes plataformas:
