- Georgia Taylor - Ruth Winters
- Nigel Anthony - Ted Roach
- Debbie Roza - Susie Mercer
- Vivienne McKone - Julie Stevens
- Mamta Kaash - Beth Ramanee
- Eddie Nestor - Cyril James
- Chelsea Halfpenny - Alicia Munroe
- Azuka Oforka - Louise Tyler
- Lloyd Everitt - Jez Andrews
- Paul Lacoux - David Rowe
- Maureen O'Brien - Elizabeth Straker
- Nigel Le Vaillant - Julian Chapman
- Kip Gamblin - Greg Fallon
- George Harris - Clive King
- Lisa Bowerman - Sandra Mute
- Bernard Gallagher - Ewart Plimmer
- Robert Pugh - Andrew Ponting
- Helena Little - Mary Tomlinson
- Christopher Rozycki - Kuba Trzcinski
- Carol Leader - Sadie Tomkins
- Susan Franklyn - Valerie Sinclair
- Shaheen Khan - Kiran Joghill
- Tam Hoskyns - Lucy Perry
- William Gaminara - Andrew Bower
- Brenda Fricker - Megan Roach
- Robson Green - Jimmy Powell
- Maggie McCarthy - Helen Green
- Geoffrey Leesley - Keith Cotterill
- Adie Allen - Kelly Liddle
- Emma Bird - Maxine Price
- Anne Kristen - Norma Sullivan
- Jason Riddington - Rob Khalefa
- Catherine Shipton - Lisa 'Duffy' Duffin
- Julia Watson - Barbara Hayes
- Julia Watson - Barbara 'Baz' Samuels
- Suzanna Hamilton - Karen Goodliffe
- Christopher Guard - Ken Hodges
- Doña Croll - Adele Beckford
- Oliver Parker - Mark Calder
- Naoko Mori - Mie Nishi-Kawa
- Jane Gurnett - Rachel Longworth
- Sorcha Cusack - Kate Wilson
- Steven Brand - Adam Cooke
- Jason Merrells - Matt Hawley
- Sue Devaney - Liz Harker
- Craig Kelly - Daniel Perryman
- Lisa Coleman - Jude Kocarnik
- Gray O'Brien - Richard McCaig
- Ganiat Kasumu - Gloria Hammond
- Jonathan Kerrigan - Sam Colloby
- Paterson Joseph - Mark Grace
- Peter Birch - Jack Hathaway
- Claire Goose - Tina Seabrook
- Vincenzo Pellegrino - Derek 'Sunny' Sunderland
- Rebecca Wheatley - Amy Howard
- Gerald Kyd - Sean Maddox
- Jan Anderson - Chloe Hill
- Ian Kelsey - Patrick Spiller
- Sandra Huggett - Holly Miles
- Michelle Butterly - Mel Dyson
- Zita Sattar - Anna Paul
- Philip Bretherton - Andrew Bower
- Will Mellor - Jack Vincent
- Neet Mohan - Rash Masum
- Neet Mohan - Rashid Masum
- Ronnie McCann - Barney Wolfe
- Lee Warburton - Tony Vincent
- Kelly Harrison - Nikki Marshall
- Christine Stephen-Daly - Lara Stone
- Maxwell Caulfield - Jim Brodie
- Leanne Wilson - Claire Guildford
- Louise Brealey - Roxanne Bird
- Sarah Manners - Bex Reynolds
- Elizabeth Carling - Selena Donovan
- Elizabeth Carling - Selena Manning
- Mark Bonnar - Bruno Jenkins
- Susan Cookson - Maggie Coldwell
- Will Thorp - Paul 'Woody' Joyner
- Janine Mellor - Kelsey Phillips
- Joanne King - Cynthia 'Cyd' Pyke
- Matthew Needham - Toby De Silva
- Tristan Gemmill - Adam Trueman
- Daphne Alexander - Nadia Talianos
- Sunetra Sarker - Zoe Hanna
- Ella WIlder - Shirley Franklin
- Maureen Beattie - Sandra Nicholl
- Lizzy McInnerny - Laura Milburn
- Steven O'Donnell - Frankie Drummer
- Mandip Gill - Nasreen Mahsud
- Maddy Hill - Ruby Spark
- Will Sharpe - Yuki Reid
- Uriel Emil Pollack - Lev Malinovsky
- Olivia D'Lima - Fenisha Khatri
- Patrick Robinson - Martin 'Ash' Ashford
- Jason Durr - David Hide
- Kirsty Mitchell - Faith Cadogan
- Di Botcher - Jan Jenning
- Clive Mantle - Mike Barratt
- Clive Mantle - Robert Forbes
- Jack Nolan - Will Noble
- Amanda Mealing - Connie Beauchamp
- Richard Winsor - Caleb Knight
- Osi Okerafor - Matthew Afolami
- Jacey Sallés - Rosa Cadenas
- Adele James - Christina "Tina" Mollett
- Anna Chell - Jodie Whyte
- Sarah Seggari - Rida Amaan
- Barney Walsh - Cameron Mickelthwaite
- Barney Walsh - Cam Mickelthwaite
- Adesuwa Oni - Ngozi Okoye
- Manpreet Bachu - Tariq Hussein
- Sammy T. Dobson - Nicole Piper
- Nigel Harman - Max Cristie
- Shalisha James-Davis - Paige Allcott
- Eddie-Joe Robinson - Ryan Firth
- Kellie Shirley - Sophia Peters
- Ryan Hawley - Jamie Cleveland
- Michael Keogh - Rich Walker
- Deborah Moore - Vicky Heaton
- Tony Marshall - Noel Garcia
- Tony Marshall - Roy
- Robert Gwilym - Max Gallagher
- Robert Gwilym - Howard Collier
- Kwame Kwei-Armah - Finlay Newton
- Kwame Kwei-Armah - Lloyd Wincott
- James Redmond - John 'Abs' Denham
- James Redmond - Abs Denham
- George Rainsford - Ethan Hardy
- George Rainsford - Alexander Forbes-Blackwell
- Matt Bardock - Jeff Collier
- Matt Bardock - Terry
- Melanie Hill - Siobhan McKenzie
- Melanie Hill - Janice Hutchins
- Suzanne Packer - Tess Bateman
- Suzanne Packer - Candice Francis
- Jamie Glover - Patrick Onley
- Jamie Glover - Luke
- Gillian Kearney - Jessica Harrison
- Gillian Kearney - Mandy
- Luke Bailey - Sam Bateman
- Luke Bailey - Ben
- Martina Laird - Comfort Jones
- Martina Laird - Pauline
- Jonny Coyne - Roger Morgan (as Jonathan Coyne)
- Freddie Stroma - James Huppert
- Maria Friedman - Trish Baynes
- Maria Friedman - Trish Barnes
- Justine Francesca Glenton - Karen Wilkes (as Justine Glenton)
- Basienka Blake - Elena Stanev
- Shobna Gulati - Preethi Chhabra
- Indira Joshi - Supriya Chhabra
- Joy Blakeman - Julie Morry
- Ray Burdis - Alan 'Dusty' Binns
- Liam Barr - Glenn Wilson
- Roger Ostime - Norman Parker
- Phil McCall - Starchy Harris
- Trevor Cooper - Ralph
- Al Hunter Ashton - Robert Palmer
- David Simeon - Bob Bates
- Zelah Clarke - Ruth White
- Jane Hazlegrove - Kathleen"Dixie" Dixon
- Jane Hazlegrove - Jane
- Paul Moriarty - Ray Blackwell
- Shaheen Jafargholi - Marty Kirkby
- Shaheen Jafargholi - Christy Skinner
- Graham Fletcher-Cook - Kevin Blackwell
- Rebecca Lacey - Georgina 'George' Woodman
- Rebecca Lacey - Louise Tomlin
- Rebecca Lacey - Debbie
- John Flanagan - Det Sgt Fox
- Patsy Smart - Winnie
- Alfred Molina - Harry Horner
- James Snell - Mr. Thalton
- Sarah Moore - Carrie
- Michael Culver - James
- Betty Alberge - Mrs. Davies
- Mark Jones - Tom
- Charles Lamb - Harry
- Wally Thomas - Lagger
- Victoria Hasted - Gillian Plimmer
- Shelley King - Rama Patel
- Elvis Payne - Henry McCartney
- Sean Scanlan - Alex
- Christopher Douglas - Mr Radford
- Roberta Tovey - Mrs. Radford
- Keith Jayne - Luke
- Sebastian Abineri - David
- John Forgeham - Sgt. Shaw
- Jaye Griffiths - Ellie Gardner
- Jaye Griffiths - Sheena Whitehead
- Harold Goodwin - Mr. Collee
- Janine Duvitski - Joyce
- Colin McCormack - Gregory Newman
- Christopher Fairbank - Gerald Bryant
- Mela White - Sonia Blackwood
- Lorraine Ashbourne - Sandy
- Jackie Lye - Wanda the Anaconda
- Dee Sadler - Maggie
- Peter Amory - Guy
- Pam Ferris - Linda
- Sophie Thompson - Judy Wilson
- Emer Gillespie - Miss Harris
- Eric Deacon - Peter
- Roger Hammond - The Man
- Ray Mort - Albert Monday
- John Hallam - Big Ted
- Bryan Pringle - George Tomlinson
- Jonathan Oliver - Brendan
- Elyes Gabel - Gurpreet 'Guppy' Sandhu
- Elyes Gabel - Jude
- Elyes Gabel - Jean-Claude Tournier
- Kevin McNally - Tom Bennod
- Kate Lock - Sophie Bennod
- Roger Brierley - Coroner
- Joseph Brady - George Dunwoody
- Francesca Hall - Viv Baxter
- Julia Deakin - Jill
- Nicholas Barnes - Eric
- Paul Ridley - John Groves
- Andrea Gordon - Sandra
- Julian Wadham - Rev. Tony Vassar
- Sebastian Shaw - Charles Howlett
- Caroline John - Edith Howlett
- Peter-Hugo Daly - Roger West
- Lesley Nightingale - Monica West
- John Ringham - Keith Cunningham
- Brian Capron - Peter
- Daphne Oxenford - Mrs. Johnson
- Mark Strickson - Gynaecological Registrar
- Bradley Cole - Tony
- David Garfield - Don Lockhart
- Roy Kinnear - Brian McCarthy
- Clarence Smith - Colin
- Simon Dormandy - Tom
- Rebecca Saire - Polly
- John Bowler - Richard Leighton
- Tip Tipping - Car Driver
- Tip Tipping - Wayne
- Anne Dyson - Granny
- John Challis - Harry
- George Irving - Paul
- James Ottaway - Edwin Palmer
- Paul Alexander - Gordon Howard
- Felicity Steel - Ruth Howard
- Albert Welling - Terence
- Sadie Frost - Natasha
- Nick Orchard - Dr. Chris Alton
- Jill McCullough - Lucy Potter
- Andy de la Tour - Bill Potter
- Peter Caffrey - Seamus
- Peter Caffrey - Patrick
- Richard Vernon - Dr. RIchard Payton
- Gwen Nelson - Miss Dalrimple
- Barry Stearn - Kevin Forbes
- Pat Roach - Len
- Stephen Tompkinson - PC Tony Mitton
- Derek Benfield - Mr. Davies
- Derek Benfield - Eric Hogarth
- Sean Pertwee - PC Nick Johns
- Johanna Hargreaves - Gail McCartney
- Johanna Hargreaves - Debbie Bannister
- Michael Bray - Hugh
- Christopher Driscoll - Paul Rulton
- Maggie Ollerenshaw - Beverley Miles
- Robert Patterson - Eric
- Russell Hunter - Edwin Crew
- Erick Ray Evans - Howard Stanton
- Mary Tamm - Virginia Wilson
- David Kinder - Richard Cumming
- Freddie Boardley - Tom Longworth
- Mark Straker - PC Rogers
- Richard Lumsden - Phil
- Mike O'Malley - Arthur Drury
- Conleth Hill - Rob
- Edward Judd - Alfred Newcombe
- Rod Culbertson - Graham Newcombe
- Robert Austin - Father Dominic
- Edward Jewesbury - Ivor Maitland
- Christopher Villiers - Mr. Lewis
- Sarah Sutton - Sarah Dryden
- Jamie Davis - Max Walker
- Jamie Davis - Guy Masterson
- Graeme Du Fresne - Bobby French
- Tim Healy - Ken Gardiner
- Elaine Donnelly - Dawn Gardiner
- Badi Uzzaman - Bharat Patel
- Lia Williams - Carrie Langman
- Julian Fellowes - Mr. Flannagan
- Maria Charles - Miss Phelan
- Stephen Bent - Alan Hillage
- June Page - Jean Hillage
- Gil Brailey - Mrs. Curtis
- John Pennington - Mr. Curtis
- Angela Down - Liz
- Peter Marinker - Graham
- Siobhan Burke - Dawn
- Sukie Smith - Anna
- George Innes - Geoff Coxon
- Anna Lindup - Emma Foster
- Penny Bunton - WPC Martin
- Patricia Hayes - Mrs. Calthorne
- Frank Windsor - Kenneth Samuels
- Frank Windsor - Leslie Smith
- John Cassady - John Redpath
- Barbara Marten - Tamara Redpath
- Caroline Quentin - Jane Locke
- Michael O'Hagan - Football Manager
- Ian Burfield - Jeff
- Philip Lowrie - Simon Spencer
- Lynne Verrall - Christine
- Cherry Gillespie - Barbara Conrad
- Richard Caldicot - Max Shaw
- Bert Parnaby - Billie Jennings
- Dervla Kirwan - Anna
- Mmoloki Chrystie - Colin
- Jonathan Lacey - Ian
- Jenny McCracken - Anne Carpenter
- Geoffrey Bateman - Henry Carpenter
- Shirley Henderson - Denise
- Alan Cox - Joshua
- Tara MacGowran - Ms. Warner
- Melanie Kilburn - Mrs. Hearn
- Grant Masters - Dan Robinson
- Grant Masters - Steve Morrissey
- Amanda Boxer - Mrs. Leach
- Judy Flynn - Lorraine
- Stevan Rimkus - Danny Gresty
- John Bardon - Jack Morris
- Alison Peebles - Sarah Peterson
- Dermot Crowley - Hastings
- Robert Glenister - Duncan
- Louise Jameson - Judy
- Annabelle Apsion - Carrie Potter
- Carol Royle - Lizzie Trent
- Hilda Braid - Agnes Hartley
- Elspet Gray - Mary Porter
- Nicholas Jones - John Packard
- Michael Lees - Colonel Johnson
- David Savile - Derek Parrish
- David Savile - Mr. Stevens
- Chris Gascoyne - Simon
- Chris Gascoyne - Cliff Davies
- Chris Gascoyne - Yob
- Carolyn Pickles - Diane Robinson
- Dominic Jephcott - Peter Gosford
- Dearbhla Molloy - Eileen Walker
- Matthew Scurfield - Stan
- Fred Pearson - Frank Philpott
- Heather Canning - Thelma Philpott
- Ian Flintoff - Headmaster
- Polly Hemingway - Jenny Petersen
- Polly Hemingway - Pat Bolt
- Suzanne Bertish - Caroline Collier
- David Ellison - Ron Wilson
- Ewan Hooper - Sam Dewsbury
- Phil Rowlands - Mr. Gordon
- Phil Rowlands - Edwin Ansdell
- Tony Bluto - Brian Thomas
- Dominic Keating - Ian Tilsley
- Christopher Blake - Mike Jameson
- Louise Lombard - Clare Jameson
- Jonny Phillips - Ronnie
- Peter Gunn - Malcolm
- Geraldine Somerville - Ruth
- Kenneth Cranham - James Lawrence
- Catherine Neilson - Emma Lawrence
- Christopher Eccleston - Stephen Hills
- Joan Blackham - Mrs. Wheeler
- Ben Chaplin - Gareth Orell
- Ciaran Madden - Zoe Turner
- Felicity Montagu - Karen Forrester
- Marc Warren - Nick
- Lyndon Davies - Terry
- Christien Anholt - Jude
- Shirin Taylor - Helen Masters
- Shirin Taylor - Joan
- Karl Collins - Roy
- Sophie Okonedo - Gina Russell
- Tom Georgeson - Tim Talbot
- Jim Carter - Matthew Charlton
- Richard Ridings - Kevin
- Richard Ridings - Jack
- Jo Stone-Fewings - Mark Sutton
- Scott Edmund Lane - Danny
- Fleur Taylor - Shelley
- Rob Edwards - Adam McBride
- Benjamin Whitrow - Douglas Cranville
- Polly James - Sylvia Vaughan
- Ian Talbot - Ken Vaughan
- Andrew Wilde - Robert Frost
- Belinda Sinclair - Carole Frost
- Sheila Allen - Marcia Parrish
- Simon Chandler - Richard Penfold
- Su Elliot - Helen Hardwick
- William Armstrong - Paul
- Patti Love - Yvonne Miller
- Barrie Rutter - Ted Miller
- James Cosmo - John Breckman
- James Cosmo - Tony
- Shaun Scott - Rob Carrington
- Annie Hulley - Jan Callington
- Eleanor David - Stephanie Freeman
- Jerome Flynn - Alan Deacon
- Julia Sawalha - Nikki Watson
- Christopher Colquhoun - Simon Kaminski
- Christopher Colquhoun - Luke Hutchens
- Nicholas Le Prevost - Antony Reynolds
- Amy Melhuish - Antonia Reynolds
- Jimmy Jewel - Sid Towers
- Ken Sharrock - Kevin Price
- Ken Sharrock - Barry
- Selina Cadell - Sister Margaret
- Anthony Milner - Mike
- Katy Murphy - Kath
- Peggy Mount - Eliza Johnstone
- Jack Galloway - Jeff Dryden
- Mary Larkin - Jenny Dryden
- Kenneth Cope - Les Hocknall
- Kenneth Cope - Archie Higgs
- Ralph Riach - Alex
- Charlotte Cornwell - Chris Williamson
- Charlie Condou - David Williamson
- Neil Dudgeon - Mick
- Paul Geoffrey - William Ellis
- Breffni McKenna - Richard Lord
- Colin Tierney - Michael Letts
- Minnie Driver - Zena Mitchell
- Richard Dormer - Rick Tomlinson
- Cathryn Bradshaw - Monica Larwood
- Siobhan Redmond - Betty Jones
- Michael Attwell - Sam Jones
- Wendy Gifford - Mrs. Cox
- Daniel Peacock - Leathers
- Nicholas Caunter - Tommy
- Nicholas Farrell - Phil Byron
- Pauline Delaney - Mona Drekon
- Jeremy Bulloch - Peter Cunningham
- Jeremy Bulloch - Rodney Mulligan
- Michael Feast - Wayne Simpson
- Michael Feast - Gerry Whitmore
- Anna Cropper - Mrs. Chassnee
- Kathy Burke - Lorraine McCullier
- Meryl Hampton - Pamela Cumming
- Meryl Hampton - Anna Beckett
- Christine Kavanagh - Helen Ferris
- Simon Shepherd - John Ferris
- Gary Olsen - Gary Tate
- Tim Preece - Peter Gilchrist
- Ben Daniels - Graham Marda
- John Moulder-Brown - Hal
- Billy Murray - Don Collins
- Sharon Morgan - Jean Collins
- Eamon Boland - Tony Walker
- Eamon Boland - George Haley
- Ron Donachie - PC Pewsey
- Julia Foster - Joyce Pratkash
- Roshan Seth - Sujit Pratkash
- David Beames - Chris Dale
- Christopher Benjamin - Henry Lindall
- Ian Hogg - Bill Morgan
- Dean Harris - Mike
- Dean Harris - Simmer
- Dean Harris - Rimmer
- Pete Postlethwaite - Hank
- Pete Postlethwaite - Ralph Peters
- Shane Rimmer - Ed Rhinehart
- David Harewood - Paul Grant
- David Harewood - Leon
- Anna Chancellor - Celia Morton
- David Gwillim - Jeff Morton
- Jan Harvey - Claire
- Bernard Horsfall - Tom Baxter
- Bernard Horsfall - Dr. Alex Upchurch
- Bernard Horsfall - Gerald Lassiter
- Peter Wight - Trevor
- Anne Reid - Barbara
- John Normington - George
- Charlie Creed-Miles - Eric Newcombe
- Charlie Creed-Miles - Philip O'Connor
- Dora Bryan - Hester Blewett
- Tony Selby - Leon
- Tony Selby - Dan Kavanagh
- Betty Marsden - Naomi Blewett
- Margaret Towner - Kitty Meadows
- Ruth Sheen - Barbara George
- Peter Gilmore - Lionel
- Nicholas Gleaves - George Reynolds
- Fraser James - George
- Fraser James - Andrew Hardwick
- Michelle Fairley - Kathy Emerick
- Michelle Fairley - Kate Maguire
- Alun Lewis - Phil
- David Hargreaves - Donald Petersen
- David Hargreaves - Dennis Martin
- Lionel Jeffries - Bill Tongue
- Joseph McFadden - Alistair
- Joseph McFadden - Dave Adams
- Maxine Audley - Leah Kelvin
- Jonny Lee Miller - Matt
- Harry Towb - Sam Kelvin
- Kulvinder Ghir - Jeevan
- Kulvinder Ghir - Ahmet
- Fiona Victory - Katherine McArthy
- Juliette Caton - Jan
- Jon Croft - Fred
- Nick Moran - Jez
- Rosalind Ayres - Sarah
- Martin Jarvis - Bart
- Philip Madoc - Mike
- Rula Lenska - Circus Owner
- Rocky Marshall - Bobby
- Susan Penhaligon - Hattie Kent
- Pal Aron - Santa Claus
- Kieran O'Brien - Chris Miller
- Kieran O'Brien - Billy
- Alan Stocks - Gary Walsh
- Alan Stocks - James Dixon
- James Blackwell - PC Tony Roberts
- Jeff Rawle - Len Jackson
- Pippa Guard - Fiona
- Pippa Guard - Jill Robson
- Ian Shaw - Sean
- Amanda Redman - Olivia Purcell
- Trevyn McDowell - Louise
- Hywel Bennett - Paul Lawson
- Georgina Cates - Emily Russell (as Clare Woodgate)
- Ann Penfold - Edith
- Ann Penfold - Gwen Hayes
- Michael Cashman - Malcolm Paynter
- Julia Hills - Carole Simpson
- Con O'Neill - Denis Simpson
- Paula Wilcox - Rosalind Paynter
- Ben Brazier - Lee Chasey
- Kate Winslet - Suzanne
- Perry Fenwick - Marvin Osborne
- Perry Fenwick - Perry Snape
- Elizabeth Estensen - Madeleine Howard
- Marion Bailey - Anna Longford
- Marion Bailey - Joy Waddington
- Rob Spendlove - Supt. Pete Collier
- Rob Spendlove - Rick Westbrook
- Jemima Abey - Sarah-Lou Millar
- Paul Stocker - Dave Pattinson
- Paul Bazely - Gary Watson
- Davyd Harries - George Felton
- Davyd Harries - Barry Hoyle
- Daniel Hill - Clive
- Stefan Kalipha - Joseph Watson
- Fay Masterson - Amy Croft
- Keith Drinkel - Insp. Easton
- Kevin Dyer - Chris
- Julian Holloway - Jim
- Chowee Leow - Lee
- Elaine Lordan - Janice Bradley
- Leonard Preston - Mark Woodburn
- Sion Probert - Derek Redland
- Chris Tranchell - Ortho Registrar
- Barbara Wilshere - Val Hetherington
- Karen Salt - 'Whitney' Christine Warbin
- Karen Salt - Kasha Lewis
- Jane Wood - Elspeth McCauley
- Allan Surtees - Ray McCauley
- Anton Phillips - Errol Walmsley
- Jackie Morrison - Daisy
- John Cater - Bernard
- Leon Black - Danny
- Cliff Parisi - Malc
- Mary Miller - Hilary Kingston
- Brian Miller - Chris Sullivan
- Chris Pitt - Steve Morris
- Chris Pitt - Paul Petersen
- Brenda Bruce - Carrie Springett
- Christopher Hancock - Ted Springett
- David Burke - Ron Fisher
- Barbara Ewing - Sheila Fisher
- Joanna Riding - Jackie Walsh
- Colin Baker - Colin Miles
- Colin Baker - David Vincent
- Gary Sefton - Kevin Fisher
- Clive Rowe - Geoff Speight
- Saira Todd - Debbie Miller
- Fiona Gillies - Philippa Kinross
- Fiona Gillies - Amy Fraser
- Hermione Norris - Abby Larwood
- Hermione Norris - Bobbie Croft
- Terence Harvey - Peter Hart
- Trevor Peacock - Reg
- Julia Ford - Susie
- Liam Hess - Louis Fairhead
- Liam Hess - Stanley Wilson
- Steve Delaney - Mike Findlay
- Luke Hayden - Kieron Kennedy
- Ravi Kapoor - Tony Chopra
- John Brobbey - Phil Chambers
- Mark Mulholland - Willy
- David Doyle - Darren
- Ann Morrish - Peggy Fuller
- Tyler Butterworth - Mark
- Tyler Butterworth - Mr. Evvans
- Andy Rashleigh - Richie Mason
- Terrence Hardiman - Carlisle
- Kathleen Byron - Mrs. Anderson
- Kathleen Byron - Avril Maitland
- Kathleen Byron - Lizzie Burnley
- Julie Foy - Sue
- Claire Hackett - Sandra Bennison
- Kieron Forsyth - Eric
- Steve Weston - Kevin Bennison
- Robert Swann - Col. Eric Dutton
- Rachel Fielding - Sally
- Rachel Fielding - Charlotte Dunham
- Sheila White - Deborah Shines
- Helen Baxendale - Emma Hayes
- Colin Farrell - John Hayes
- Simon Slater - Mike Howlett
- Caroline Harker - Tessa
- Caroline Harker - Helen Bradley
- Andrew Robertson - Mr. Offenbach
- Andrew Robertson - Vic Harkness
- Amanda Root - Joyce Paice
- Jo Cameron Brown - Enid Hoyle
- Jean Anderson - Rosie Collier
- Jean Anderson - Jessie Baine
- Seamus O'Neill - Stefan
- Boris Boscovic - Kemal
- Brian Stirner - Nigel Fox
- Sara Sugarman - Kath
- Jan Chappell - Dr. Potter
- George Rossi - Giovanni Fachetti
- William Vanderpuye - Victor Cheritan
- Leslie Schofield - Ron Jenson
- Greg Hicks - Gerry Talbot
- Susan Brown - Joan Hawley
- Susan Brown - Julie
- Stuart Laing - Matt
- Mark Williams - Des Jones
- Billy Hartman - Rick
- Paul Butterworth - Bob
- Carol Burns - Jean Hall
- Michael Godley - Sir Andrew Owen
- Emma Amos - Anna Owen
- David Plimmer - Roy Welsh
- Deborah Grant - Sheila Granger
- Deborah Grant - Lucinda Arthur
- Ben Pullen - Stephen Roche
- Sarah Badel - Celia Cooke
- Kate Fitzgerald - June Williamson
- Annie Hayes - Betty Faraday
- George Sweeney - Ted Faraday
- George Russo - Billy Faraday
- Cherith Mellor - Liz Adams
- Peter Armitage - Peter Adams
- Daniel Anthony - Jamie Collier
- Daniel Anthony - Niall Gorton
- Daniel Anthony - Lee Stark
- Daniel Anthony - Tyrone Harris
- Peter McNamara - Terry Cooper
- Vicky Murdock - Alison Cooper
- Stella Tanner - Joan Cooper
- Lucy Cohu - Jayne Bazeley
- Lucy Cohu - Theresa Johnson
- Dominic Guard - Philip Hall
- Dominic Guard - Tim Turner
- Arthur Whybrow - Mr. Daniels
- Elizabeth Bradley - Mrs. Daniels
- Edna Doré - Joan Hughes
- Edna Doré - Grace Harper
- Peter Guinness - Paul Becket
- Cindy O'Callaghan - Diane Chasey
- Cindy O'Callaghan - Lynne Browne
- Derek Fowlds - Mr. Croft
- Orlando Wells - Mark Andrews
- David Ryall - Tom Harley
- David Ryall - Dr. James Baker
- David Ryall - Eddie Gash
- Jack Rowan - Sheldon Hawkins
- Linda Henry - Diane Daw
- Mark Lewis - Barry
- Andrew Read - John
- Ricci Harnett - Colin Miller
- Tat Whalley - Rory Miller
- Martin Hancock - Sam McGann
- Lee Whitlock - Graham
- Lee Whitlock - Steve Johnstone
- Des McAleer - Dave McGann
- Julie Dawn Cole - Lucy Roland
- Julie Dawn Cole - Jenny
- Julian Kerridge - PC Kevin Bradshaw
- Melvyn Bedford - PC John Milligan
- Anna Bolt - Sally Lister
- Kate Binchy - Kath Lister
- Liza Walker - Kathy Hart
- Liza Walker - Jenny Wells
- Liza Walker - Fenella Chivers
- Lee Ross - Ray
- Lee Ross - Dave
- Amy Hodge - Carly Hutchings
- Angela Catherall - Patsy
- Gabrielle Lloyd - Marian Ford
- Geoffrey Hutchings - Paul Fenwick
- Mark Kingston - Mr. Parrish
- Mark Kingston - Edward Avery
- Mark Kingston - Peter Williams
- Lavinia Bertram - Jean Fenwick
- Jack Ellis - Bernie
- Patricia Kerrigan - Sheila Norris
- Patricia Kerrigan - Alice Byron
- Noreen Kershaw - Steph
- Dorian Healy - David Collier
- Dorian Healy - Mick
- Dorian Healy - Bernard
- Dorian Healy - Tommy Harper
- Alex Lowe - Alex Hopkins
- Lesley Nicol - Jayne Bowen
- David Cardy - James Bowen
- James Lailey - Glen Quinn
- Lesley Clare O'Neill - Christine Fairhurst
- Richard Albrecht - Ray Fairhurst
- Claire Rushbrook - Policewoman
- Sadie Shimmin - Brenda Westbrook
- Will Knightley - Nigel
- Pat Keen - Mavis Watson
- Pat Keen - Emily
- Susan Jameson - Samantha Grieve
- Susan Jameson - Harriet
- Jason Watkins - Partridge
- Rowena Cooper - Adele Benson
- Rowena Cooper - Marion
- Rowena Cooper - Mrs. Parrish
- Dickon Tolson - Danny
- Martha Cope - Sylvia
- Jeillo Edwards - Jean MacKenzie
- Doreen Mantle - Mrs. Duffin
- Doreen Mantle - Renee Wainwright
- Colette Brown - Emma
- Connie Hyde - Nikki Neal
- Nicholas Frost - Fatso
- Stella Gonet - Jayne Grayson
- Stella Gonet - Dr. Clare Wainwright
- Scott Handy - Trevor Coyle
- Ben Onwukwe - Greg James
- Chris Jury - Mr. Skinner
- Bill Gavin - Alfred MacIntyre
- Pauline Quirke - Mary Taylor
- Pauline Quirke - Jackie Rogers
- T. P. McKenna - Arthur Jackson
- T. P. McKenna - Dr. Archie Whitlock
- Kenneth Farrington - Philip Jenkins
- Ann Lynn - Mary Jenkins
- Philip Whitchurch - Detective Sergeant
- Philip Whitchurch - Paul Bolt
- Philip Whitchurch - Millard
- Melissa Wilkes - Elaine Warbin
- Ian Redford - Doug Rothermere
- Gary Dunnington - Duncan Cox
- Dicken Ashworth - Alan Todd
- Deborah Findlay - Debbie Cookson
- John McGlynn - Steve Lewis
- John McGlynn - Malcolm Christy
- Angeline Ball - Shirley
- Mary Maxted - Mrs. Grace
- Rebecca Callard - Connie
- Rebecca Callard - Suzie Brennan
- Colette O'Neil - Maureen Trafford
- René Zagger - Rick
- René Zagger - Nate Durante
- René Zagger - Bob Smith
- Heather Tobias - Pam Russell
- Heather Tobias - June Richards
- Justin Chadwick - Paul
- Justin Chadwick - Steve
- David Horovitch - Roger Longford
- Victoria Finney - Trish Lathwell
- Ram John Holder - George
- Ram John Holder - Vivian House
- Stephen Moore - Alan Dunn
- Stephen Moore - Kevin
- Angela Douglas - Jane Avery
- Gina McKee - Ginnie Davies
- Tenniel Evans - Gerald Summers
- Tenniel Evans - Albert Sylvester
- Carmel McSharry - Frances Miller
- Tony Melody - Brian Miller
- Helena McCarthy - Kathy Allan
- Andrew Grainger - Joe Jobson
- Charon Bourke - Rebecca Jobson
- Fergus Brazier - Rory Jobson
- Max Brazier - Finn Jobson
- Isobel Middleton - WPC
- Isobel Middleton - WPC Tracy Hollings
- Diana Fairfax - Connie Sanders
- Barbara Murray - Vivien Guyett
- Walter Sparrow - Archie Farrell
- Pandora Colin - Joanna Farrell
- Chanda Sharma - Mrs. Singh
- Burt Caesar - Mr. Carlisle
- Christopher Gilbert - Uncle Bob
- Tracy Whitwell - Janice Draper
- Matthew Delamere - Terry
- Ken Hutchison - Mr. Draper
- Joanne Allen - Mrs. Draper
- Rosie Marcel - Stella
- Rosie Marcel - Dorothea Mikus
- Jennie Linden - Caroline Martin
- Paula Jacobs - Iris Thompson
- Sidney Livingstone - Ronnie Thompson
- John Vine - Geoff Cooper
- Tony Caunter - Cafe Owner
- Tony Caunter - Tom Stopes
- Colin Wyatt - Colin
- Andrew Scarborough - PC
- Andrew Scarborough - Gavin Turner
- Andrew Scarborough - Daniel
- Jean Heywood - Lily Harwood
- Jean Heywood - Edith Whoitmore
- Jean Heywood - Mrs. Grady
- Joseph Kpobie - David Talbot
- Joseph Kpobie - John Walmsley
- Scott Robinson - Lee
- Kevin Knapman - Ian Lester
- Suzanne Maddock - Charlotte Harrison
- Jon Finch - Graham Lester
- Carl Rice - Jason Lester
- Nick Dunning - Jack Paice
- Nick Dunning - Brian Harper
- Celia Imrie - Elizabeth Clayton
- Francois Pandolfo - Andrew Temple
- Michelle Newell - Anna Matthews
- Adam Bareham - Simon Matthews
- George A. Cooper - Albert Collins
- Cheryl Hall - Jane Turner
- Jonathan Barlow - Johnny Whitmore
- Ray Winstone - Terry Brennan
- Michael Angelis - Gordon McCauley
- Michael Angelis - Jez Ingrams
- Michael Angelis - Ollie Yates
- Jake Wood - Toby Grant
- Jake Wood - Rhys Proctor
- Rosemary Martin - Sheila Kavanagh
- Bill Stewart - Ted Andrews
- Frank Grimes - Brian Hawley
- Victoria Williams - Susan Harris
- Robert Cavanah - James Barnes
- Ben Miller - Daniel Murdoch
- Christine Pollon - Dr. Jacobs
- Andrew Woodall - Tom Hodges
- Glenn McCrory - Vlad the Impaler
- Anna Rose - Sally Porter
- Charlie G. Hawkins - Miles Stones
- Adam Paul Harvey - Kieran Batten
- Gwyneth Powell - Gloria Pots
- Guy Henry - Henrik Hanssen
- Raif Clarke - Kai Swift
- Adam Foster - Steve Swift
- Owain Arthur - Glen Thomas
- Tracey Wilkinson - Jackie Munroe
- John Duttine - Alec Howard
- John Duttine - Tom Jennings
- James Gaddas - Howard Munroe
- Mark Rice-Oxley - Roddy Swinford
- Eileen Davies - Jan Harvey
- Frances Grey - Gaynor Lockford
- Zac Gabriel Werb - Ben Lockford
- Elizabeth Edmonds - Annie O'Shaunessy
- Kate Williams - Rosie Cornwall
- Kate Williams - Stella Lawson
- Liza Goddard - Gloria Francis
- Lorraine Pilkington - Rosa Hide
- Terence Hillyer - Allan Francis
- Michael Higgs - Henry Nichols
- William Scott-Masson - Daniel Lockford
- Christopher Ellison - Danny Weaver
- Christopher Ellison - Wayne Davisson
- Alex Avery - Eli Brookes
- Frankie Fox - Joel Ronson
- Gabriel Lo Giudice - Paolo Brunetti
- Rik Makarem - Sebastian Grayling
- Sophie Austin - Tanya Duffin
- Trudie Goodwin - Karen Bartley
- Ann Mitchell - Mrs. McKenzie
- Ann Mitchell - Margaret Samson
- Ricky Nixon - Peter Duffin
- Shaun Parkes - Patrick Senior
- Shaun Parkes - Grant Flock
- Rohan Gotobed - Rhys Morry
- Denise Black - Maggie Kavanah
- Denise Black - Grace Anning
- Denise Black - Jenny Munro
- Mimi Keene - Lana Westmore
- Brenock O'Connor - Peter Barnes
- Frederick Treves - Henry Alsop
- Guy Witcher - David Alsop
- William Russell - Mo Meredrew
- Tam Williams - Shane Fisher
- Cyril Nri - Steve York
- Emily Woof - WDC Dawn Morris
- Letitia Dean - Hannah Chesney
- Liz Smith - Tillie
- Tessa Peake-Jones - Esther Macauley
- Tessa Peake-Jones - Jenny Hodges
- Tessa Peake-Jones - Tina Flannery
- David Bradley - Stanmore
- Harry Fowler - Terry
- Harry Fowler - George
- Simon Fenton - Jed Jarrold
- Tom Chadbon - Henry Williams
- Tom Chadbon - Richard Greetham
- Niall Tóibín - Desi Lavers
- David Robb - Henry Reeve-Jones
- Danny Worters - Oscar
- Steven Meo - Aiden Hendrie
- Steven Meo - Nick Collinson
- Steven Meo - Drew Hart
- Gary Beadle - Denny
- Gary Beadle - Steven Harris
- Gary Beadle - Dom
- Stuart Organ - Ken
- Rupert Holliday-Evans - Tom
- Rupert Holliday-Evans - Michael Cook
- Rupert Holliday-Evans - Frank MacBride
- Kenny Baker - Archie
- Kenny Baker - Charles Isaac
- Navin Chowdhry - Zaf
- Laura Fraser - Gemma McEnery
- Linda Bassett - Olwyn Humphries
- Ian Gelder - Jeremy
- Ian Gelder - Guy Chambers
- Ian Gelder - Arthur Swain
- Tim McInnerny - Marty Deakin
- Kate Gartside - Fiona Cox
- Timothy Bateson - Ronald Horton
- Oscar James - Franklyn Ashford
- Don Henderson - Jerry Hunter
- Kelda Holmes - Shelley Miles
- Josh Maguire - James Leonard
- Eddie Marsan - Rick Grant
- Jonathan Newth - Dr. Elliott
- Nicholas Hoult - Craig Morrissey
- Jo-Anne Stockham - Paula Morrissey
- Jack Deam - Lee
- Jack Deam - Danny Robertson
- Julian Glover - Arnold Richardson
- Julian Glover - Sebastian Farrow
- David Daker - Jim Porteous
- Martino Lazzeri - Kenny
- David Hayman - Phil Davies
- Amita Dhiri - Dr. Julia Kaash
- Kevin Bishop - Nick Wilson
- Orlando Bloom - Noel Harrison
- Tilly Vosburgh - Jody Ingram
- Tilly Vosburgh - Mary Tyler
- Tilly Vosburgh - Linnie Lowther
- Tilly Vosburgh - Sheila Noga
- Matthew Marsh - Geoff Marks
- Matthew Marsh - Russell Miller
- Matthew Marsh - Brian Carroll
- Nadia Sawalha - Dr. Robyn McCormack
- Judy Campbell Exner - Alice Polston
- Joseph O'Conor - George Polston
- Phyllis Calvert - Mary
- David Schofield - Detective Inspector Logan
- Emma Vansittart - Dannie Bennett
- Emma Vansittart - Roberta Stair
- Derek Riddell - Jeff Marriot
- Michael Cronin - Chief Superintendent Walker
- Luke Brown - Carl Francis
- Matilda Ziegler - Nula Snape
- Parminder Nagra - Asha Guptah
- Parminder Nagra - Alisha
- Jason Connery - James Dunham
- Pete Lee-Wilson - Brian Foster
- Pete Lee-Wilson - Daniel Warwick
- Pete Lee-Wilson - Terry Mullett
- Ronald Pickup - Martin / Reginald Freeborn
- Sean Gilder - D.S. Hennessy
- Sean Gilder - DS Hennessy
- Sean Gilder - D.I. Langen
- Sean Gilder - DS Langen
- Jamie O'Brien - Ben Lowther
- Neil Maskell - Luke Lowther
- Lucy Speed - Kerry
- Maurice Denham - William Turnbull
- Danny Cunningham - Alistair Murrell
- Danny Cunningham - Steve
- Joseph May - Paul
- Angela Pleasence - Catherine
- Angela Pleasence - Sonia
- Lynda Rooke - Jill Lester
- Lynda Rooke - Beth Harper
- Kim Hartman - Roz Felton
- Tracy-Ann Oberman - Zoe Garrard
- Frances Tomelty - Annie McGann
- Frances Tomelty - Morven Tasker
- Andrew Lancel - Chris Perry
- Andrew Lancel - Peter Becket
- Andrew Lancel - PC William 'Bill' Wise
- Jesse Birdsall - Norman Kerr
- Jesse Birdsall - Mike
- Geoffrey Bayldon - James Ellington
- Geoffrey Bayldon - Ralph Michaels
- Geoffrey Bayldon - Wilf Simpson
- Geoffrey Bayldon - Duncan Frain
- Shaun Dooley - Fire Officer
- Shaun Dooley - Fireman
- John Salthouse - Frank Swedener
- John Salthouse - Chris Weston
- Lorraine Chase - Bonnie Russell
- Andrew Knott - Garth
- Rosie Rowell - Pam Wilson
- Neil Stuke - Tony
- Elizabeth Spriggs - Barbara Thomas
- Adrian Rawlins - Richard Thomas
- Tobias Menzies - Frank Gallagher
- Martin Freeman - Ricky Beck
- Iain Cuthbertson - Dermot Needle
- Iain Cuthbertson - Albert
- Iain Cuthbertson - Eddie
- Adam Godley - Alan Decker
- Denis Lill - Walter Fisher
- Denis Lill - Tom Porter
- Norman Wisdom - Mr. Cole
- Harry Capehorn - Danny Johnson
- Lynda Bellingham - Steph Yates
- Andrew Schofield - Pete North
- Kenneth Colley - Paddy
- Kenneth Colley - Clifford Watkins
- Kenneth Colley - Arthur Cobb
- Bryan Murray - James Roberts
- Michael French - Nick Jordan
- Nicola Stephenson - Julie Fitzjohn
- Jennifer Hennessy - Gemma Fisher
- Sean Chapman - Ron Meadway
- Sean Chapman - Tom Wernik
- Trevor Byfield - Security Man
- Trevor Byfield - Don Harrikent
- Desmond McNamara - Tom Logan
- Anna Wing - Milly Soames
- Anna Wing - Binnie
- Simon Day - Cardiothoracic Surgeon
- Eros Vlahos - Liam Hendricks
- Louis Mahoney - Tom Cavanagh
- Sam Kelly - Percy Miles
- Sam Kelly - John Clayton
- Des O'Malley - Sean Bell
- Glen Berry - Russell
- Helen Lederer - Maria Harrop
- Helen Lederer - Dr. Hilary Oppe
- Tony Haygarth - Frank Thorp
- Tony Haygarth - Martin Ridley
- Scott Neal - Danny Mason
- Ewan Bailey - Nick
- Larissa Kouznetsova - Anna Allen
- Adjoa Andoh - Colette Griffiths
- Adjoa Andoh - Colette Kierney
- Adjoa Andoh - Maggie
- Amanda Abbington - Jen Reynolds
- Barnaby Kay - Gareth Mullins
- Tracie Bennett - Sally
- Tracie Bennett - Seonaidh Lucas
- Doreene Blackstock - Carole Williams
- Paul Barber - Mungo
- Paul Barber - Cliff Sidwell
- Paul Barber - Taylor Blair
- Paul Barber - William Paynter
- Paul Barber - Carl Meyers
- Sharon Duce - Sheila Denham
- Sharon Duce - Thea
- Sharon Duce - Alesia Pamboris
- David Calder - Phillip Perry
- David Calder - Roy Parks
- Roy Barraclough - Arthur Lyle
- Simon Meacock - Richie
- Craig Heaney - Dean
- Dax O'Callaghan - Dominic Taylor
- Ben Hull - Nick Harvey
- Ben Hull - Dale Charters
- Nick Brimble - Bob Taylor
- George Costigan - Stephen Gregory MP
- George Costigan - Robert
- George Costigan - Martin Gregory
- George Costigan - Father Vincent McConnell
- Derek Griffiths - Duke Bains
- Jason Hughes - Kev
- Jason Hughes - Carl Williams
- Michael Jayston - Ian
- Michael Jayston - David Northwick
- Ann Bell - Celia
- Larry Lamb - Father Peter Harker
- James Carlton - Drew Kavanah
- Brian Murphy - Walter Burnley
- Sally Hawkins - Emma Lister
- John Drummond - Keith Welsh
- Nicola Bryant - Susan Harris
- Peter Copley - Dan Woods
- Peter Copley - Hugh Phipps
- Frank Middlemass - Leonard Huckerby
- Tony Robinson - Reg Podmore
- Una Stubbs - Joan Bannville
- John Hasler - Lee Carter
- John Henshaw - Lenny Adams
- Terence Beesley - Tim Harris
- Terence Beesley - Trevor Bennett
- Terence Beesley - Bill Halliwell
- Sylvano Clarke - Andy
- Honeysuckle Weeks - Diane Gibson
- Paul Bown - Ed Connors
- Joe Swash - Denny Ingram
- Carol Drinkwater - Frances Lawson
- Matthew Lockwood - Joel Patterson
- Steve Huison - Phil Rees
- Graham McTavish - Gerry Talbot
- Graham McTavish - George Naseby
- Murray Head - Billy Cooper
- Jenny Seagrove - Summer
- Beverley Callard - Laura Hughes
- Callum Blue - Paul Hughes
- Ashley Jensen - Stella
- Ashley Jensen - Jess
- Nasser Memarzia - Amir Haron
- Nasser Memarzia - Patrick Sabet
- Brigit Forsyth - Margaret Pearce
- Brigit Forsyth - Patricia Baxter
- Michael Troughton - Chris Thomas
- Sean Harris - Tim Vanner
- Peter England - TC
- Peter England - Sam Carson
- Peter England - Martin Galloway
- Jamie Foreman - Gil Stephens
- Jamie Foreman - Henry
- Jamie Foreman - Phil Pearson
- Windsor Davies - Robert Cox
- Janet Dibley - Amanda Lewis
- Scott Chisholm - Harry Butler
- Annette Badland - Jenny Chinton
- Annette Badland - Jodie Forbes
- Annette Badland - Angela Mason
- Annette Badland - Shirley Baldwin
- Daniel Ryan - Mark Hitchens
- Daniel Ryan - Marcus Tiverton
- Joanne Froggatt - Lucy Curry
- Marina Sirtis - Jane Taylor, MP
- Harry Eden - Matty Tate
- Mark Womack - Sean Malin
- Mark Womack - Andy Stedding
- Frankie Fitzgerald - Jack Woodfield
- Frankie Fitzgerald - Russell
- Margi Clarke - Shirley Warner
- Sharon Maughan - Victoria Bevins
- Frank Thornton - Edward Gutheridge
- Dimitri Leonidas - Ross
- Ben Maguire - Matt Thompson
- Simon Merrells - Ed Jamieson
- Noel Clarke - Danny Oldfield
- Henry Ian Cusick - Jason
- Jayne Ashbourne - Stephanie Luscombe
- Jayne Ashbourne - Mary
- Aidan David - Jason Forster
- Aidan David - Carl Pearce
- Charles Kay - Professor Weinberg
- Avin Shah - Rupert
- Steven Duffy - Johnny Shears
- Rosie Cavaliero - Carmel Ramsey
- Max Wrottesley - Alex Tyler
- Sendhil Ramamurthy - Ron Montague
- Patsy Kensit - Charlotte Leith-Jones
- Ivan Kaye - Guy
- Richard Armitage - Craig Parker
- Tony Guilfoyle - Watch Commander
- Aidan McArdle - James O'Hearne
- Nicola Stapleton - Kay Larcombe
- Nicola Stapleton - Shirley Smith
- Angel Coulby - Sally
- Chad Shepherd - Rob Jones
- Michael Praed - Chris Meredith
- Freddie Jones - Henry Wallowski
- Freddie Jones - Iain Roles
- David Bamber - Dr. Martin Campbell
- Gerard Horan - Neville O'Connor
- Gerard Horan - Mark
- Griff Rhys Jones - Paul Fuller
- Mo Sesay - Herbie Akimbaye
- Mo Sesay - Robbie Aldington
- Stuart McGugan - Martin Davidson
- Sue Perkins - Dr. Lloyd
- David Paisley - Ben Saunders
- Bruno Melling - John Pawley
- Bruno Melling - Louis Richins
- Matthew Gillespie - Ollie Harper
- Ian Aspinall - Mubbs Hussein
- Siwan Morris - Sabine
- Joe Absolom - Benny Steele
- Joe Absolom - Howard Jarrold
- Hilary Maclean - Hannah Watkinson
- Hilary Maclean - Susan Napier
- Bernard Kay - Kevin Elkins
- Stefan Dennis - Mark Christie
- T.J. Ramini - PC Russell
- T.J. Ramini - PC Atkins
- Matyelok Gibbs - Nora Linton
- Jane Lapotaire - Maureen
- Jane Lapotaire - Eileen Jarvis
- Gareth Thomas - Jim Bailey
- Susan Vidler - Lina
- Susan Vidler - Pat Brennan
- Hugh Quarshie - Gordon Hutchens
- Hugh Quarshie - Ric Griffin
- Seb Castang - Andy Wells
- Lucinda Curtis - Ms. Marston
- Orlando Seale - Merlin Jameson
- Peter Vaughan - Henry Lambert
- David Walliams - Jon Fielding
- Louisa Milwood-Haigh - Vicki Allen
- Louisa Milwood-Haigh - Jane Statham
- Freddie Annobil-Dodoo - Joey Baxter
- Freddie Annobil-Dodoo - Frankie Whittock
- Daniel Ainsleigh - Jason Rees
- Victor McGuire - Father Frank
- Asier Newman - Casey
- Asier Newman - Dan Forino
- Eileen Nicholas - Mary Calthorn
- Eileen Nicholas - Alma Hobbes
- Paul Reynolds - Kev Crowley
- Paul Reynolds - Roddy Scotton
- Paul Reynolds - Alan Morgan
- Ellie Beaven - Sarah Griffiths
- Ellie Beaven - Sally Toner
- Sharon Maiden - Patsy Harris
- Paul J. Medford - Joe Freeman
- Tim Plester - Derek Moberley
- Jordan Metcalfe - Andy Murphy
- Jordan Metcalfe - Huck
- Gwyneth Strong - Elizabeth Brodie
- Tony Slattery - Michael Chambers
- Rory Jennings - Danny Miller
- Rory Jennings - Kevin Bingham
- Rory Jennings - Ashley
- David Troughton - Eddie West
- John-Paul Macleod - Toby Borodin
- Gareth David-Lloyd - Darrell Kemmer
- Oliver Ford Davies - The Major
- Oliver Ford Davies - Ziggy Rustin
- David Gyasi - Bryce
- Diana Weston - Mavis Taylor
- Danny John-Jules - Leon
- Lucy Benjamin - Gina Taylor
- James Ellis - Reg
- Amelda Brown - Linda
- Amelda Brown - Irene Richards
- Gary Mavers - DI Will Manning
- Mary Wimbush - Lily
- Prunella Scales - Jocelyn Anderson
- Christopher Timothy - Karl Ackerman
- Ryan Conway - Jason Kennedy
- Jamie Thomas King - Jamie Canning
- Charles De'Ath - Rosco
- Charles De'Ath - Matt Greer
- Charles De'Ath - Alan Crozier
- Richard Rycroft - Thomas Banks
- Richard Rycroft - Barry
- Geoffrey Beevers - Francis Twine
- Thomas Byrne - Zack Lesser
- Matt Kane - Danny Chandler
- Imogen Poots - Alice Thornton
- June Watson - Ruth Norris
- June Watson - Ruth
- June Watson - Ruth Reynolds
- Christian Cooke - Jude Becket
- Christian Cooke - Mark Booth
- Diana Coupland - Lily Thirlwell
- Jeremy Swift - Noah Fitch
- Freema Agyeman - Kate Hindley
- Liam Noble - Terry Hollingsworth
- Bobby Smalldridge - Casey Midsummer
- Bobby Smalldridge - Jacob Broker
- Dougie Poynter - Dougie Poynter
- John Woodvine - Reg Macready
- John Woodvine - Jack Hetherington
- Harry Judd - Harry Judd
- Danny Jones - Danny Jones
- Paul Copley - Arthur
- Paul Copley - Frederick Chambers
- Paul Copley - Mick McCarthur
- Tom Fletcher - Tom Fletcher
- Daniel Brocklebank - Tom Watkins
- Daniel Brocklebank - Greg Althorpe
- Joanna Kanska - Ingrid
- Joe McGann - Abe
- Joe McGann - Wyatt Newbury
- Joe McGann - Bobby Masters
- Joe McGann - Greg Flowers
- Joe McGann - Martin White
- Brian Cant - Billy Hargreaves
- Clive Russell - Billy McCabe
- Clive Russell - Jon Marston
- Clive Russell - Dave McCray
- Clive Russell - Ellis
- Clive Russell - Callum Robertshaw
- Imogen Stubbs - Chloe Greer
- Austin Drage - Jason O'Donnel
- Josie D'Arby - Stevie Bishop
- Martin Compston - Matty Howell
- Ian Lavender - Benny Jenkins
- Ian Lavender - Gordon Cunningham
- John McArdle - Mick Garland
- John McArdle - Frank Morgan
- John McArdle - Pete Ellington
- Susannah York - Helen Grant
- Sara Crowe - Kerry Summerston
- Dean Andrews - Reg Summerston
- Mark Lewis Jones - Allsop
- Mark Lewis Jones - Caleb Flack
- Katherine Parkinson - Helen Gibbons
- Max Brown - Simon Broughton
- Raymond Pickard - Mikey Rees
- Raymond Pickard - Dean Curran
- Martin Benson - Rudy Goldspink
- Damien Nash - Jo-Jo Harker
- Russ Abbot - Simon Lancaster
- Russ Abbot - Malcolm Crowson
- Thomas Law - Matt Haddon
- Roy Dotrice - George Tunstall
- Sylvester McCoy - Ashley Millington
- Sylvester McCoy - Kev the Rev
- Simon O'Brien - Jon Gartshore
- Stacey Cadman - Sabrina Watkins
- Stephen McGann - Sam Roach
- Stephen McGann - Garry Lesser
- William Mannering - Gareth Price
- William Mannering - Jamie Joyce
- Blake Ritson - Daniel Tasker
- Eva Pope - Josie Barker
- Eva Pope - Simone Grayson
- Andrew Falvey - PC James
- Keith-Lee Castle - Leaky
- Keith-Lee Castle - Phil
- Ed Westwick - Johnny Cullin
- Daniel Roche - Douglas Calvin
- Arnold Oceng - Solomon 'Sol' Lakah
- Jumayn Hunter - Richard 'Mags' Keely
- David Yip - Jiang Guang
- Angela May - Jiang Zhen Juan
- Tom Wu - Huang Lok
- Tom Hudson - Jamie Coldwell
- Robert James-Collier - Martin Stonewell
- Ramon Tikaram - Sunil Chawhan
- Ramon Tikaram - Darren Wilson
- Ramon Tikaram - Jonty Jones
- Aaron Taylor-Johnson - Joey Byrne
- Robert Timmins - Hal Nicholson
- Danny Sapani - Walker Bennett
- Danny Sapani - Paul Caffrey
- Gillian Taylforth - Justine Walker MP
- Gillian Taylforth - Gloria
- Gary Webster - Ned Prior
- John Bowe - Mike Hornsey
- Elizabeth Rider - Josephine O?Bryan
- Elizabeth Rider - Bev Elliott
- Zac Fox - Jason Anning
- Alan Williams - Roy Scaddon
- Alan Williams - Roy Harvey
- Stephen Marcus - Tommy Indler
- Patrick Baladi - Sam Fulton
- Patrick Baladi - Gary Rix
- Gary Oliver - Andy Barnes
- Gary Oliver - Eduardo Perella
- Stephen Moyer - Dr. Mark Ellis
- Charlie Brooks - Sally Montgomery
- Emily Carey - Grace Beauchamp
- Emily Carey - Grace Beauchamp-Strachan
- Keir Mills - Paul Rugg
- Garry Cooper - Han Dybendak
- Garry Cooper - Dominic 'Dom' Pearson
- Philip McGinley - Ben Bradshaw
- Philip McGinley - PC Simon Dartford
- Andy Rush - Craig Heywood
- Andy Rush - Jase Spears
- Jacqueline Pearce - Elspeth Lang
- Craig Roberts - Darren Smith
- Craig Roberts - Jordan Philpot
- Kevin Doyle - Barry Ricks
- Kevin Doyle - Dennis Tooms
- Kevin Doyle - Alan Callerton
- Josette Simon - Sarah Keith
- Gudrun Ure - Isabel
- Gudrun Ure - Violet Brook
- Gudrun Ure - Kath Berry
- Tommy Knight - Liam Woodbridge
- Tommy Knight - Jugg
- Steven Hartley - Philip Miller
- Liam Boyle - Alan Jessup
- Michelle Holmes - Jo Bishop
- Michelle Holmes - Jean Ashton
- Michelle Holmes - Donna Bridges
- Mark Monero - Tim
- Mark Monero - Gary
- Ralph Ineson - Raymond Thurber
- Ralph Ineson - Martin Woodbridge
- Tom Hiddleston - Chris Vaughan
- Angus Deayton - Himself
- Tim Dantay - Trevor
- Tim Dantay - Dave Lewis
- Ben Lloyd-Hughes - Colm Roach
- Peter O'Brien - Theo 'Stitch' Lambert
- Tom Hopper - Hugh 'Chewy' Mullen
- Christine Tremarco - Linda
- Christine Tremarco - Sarah Jennings
- Georgia Tennant - Elaine Walker
- Kate Miles - Kaz Quinn
- Ian McElhinney - Robert Finch
- Geoffrey Hughes - Si Blake
- Steve Evets - Maddox McCarthy
- Roy Hudd - George Wallace
- Nicholas Courtney - Claude Devigny
- Sean Verey - Corin Mulhearn
- Neil Newbon - Adam Hamer
- Nigel Terry - Denny Davidson
- Emily Corrie - Nell Mendez
- Shane Zaza - Sunny Sagar
- Caroline Langrishe - Marilyn Fox
- Lesley Dunlop - Angela Hartshorne
- Josef Altin - Steven Hooper
- Josef Altin - Keanan
- Josef Altin - Andy 'Mez' McKenzie
- Richard Dillane - Sean Anderson
- Richard Dillane - Anthony Sharman
- Callum Dixon - Billy Napier
- Callum Dixon - Tony Ryman
- Anthony Flanagan - Steve Harwood
- Siobhan Finneran - Sue Stedding
- Siobhan Finneran - Mel Riley
- Dean-Charles Chapman - William Mulhern
- Jean Boht - Doris Quinn
- Jean Boht - Dorothy Gilbert
- Jean Boht - Lil Clark
- Rosemary Leach - Miranda Watts
- Amy Pemberton - Jodie Daley
- Oliver Kieran-Jones - Jonas Saville
- Gregory Foreman - Louis Fairhead
- Cherie Lunghi - Camille Windsor
- Kate Buffery - Fiona Atwell
- Bill Treacher - Howard Boylan
- Anita Dobson - Rachel Lan
- Anita Dobson - Elaine Carrington
- Anita Dobson - Cora
- Rebecca Ryan - Leah Crawford
- Rebecca Ryan - Kat Ashton
- Michael Brandon - Mike Barnicott
- Maureen Lipman - Hannah 'Hayley' Liddell
- Lindsey Coulson - Kate Villiers
- Aisling Loftus - Jo Balmayne
- Moustafa Chousein-Oglou - Oddbod
- Raquel Cassidy - Monica Batchelor
- Rhys Thomas - Dr. Doom
- Jaimi Barbakoff - Emma Nash
- Jaimi Barbakoff - Cheryl O'Shaunessy
- Lysette Anthony - Rachel Houston
- Lysette Anthony - Amanda
- Jacob Anderson - Dom Parke
- Sarah-Jane Potts - Ellie Bridges
- Sarah-Jane Potts - Ellie
- Sarah-Jane Potts - Ellie Merrick
- Richard O'Callaghan - Eddie Morris
- Paul Fox - Simon Tanner
- Mark Little - Gary Forrester
- Margaret John - Mrs. Treaver
- Bernard Lloyd - Joe Geraghty
- Aneurin Barnard - Damien
- Jamie Lomas - Nathan Simmonds
- Jamie Lomas - Barry Southern
- Harry Collett - Ollie Hide
- Harry Collett - Seb Durante
- Danny Emes - Lucas Anderson
- Danny Emes - Lucas
- Joseph Morgan - Tony Reece
- Dudley Sutton - Arthur
- Mark Eden - Bill
- Frances Barber - Nancy
- Lee Williams - Brian
- Sylvia Syms - Mrs. Bullock
- Sylvia Syms - Bunny Tyrill
- Simon Williams - Professor De Silva
- Jamie Blackley - Seb Wilton
- Trevor Bannister - Mr Walter
- Ceallach Spellman - Daniel
- Chris Bisson - Carl
- James Dreyfus - Rory
- Nickolas Grace - Dennis
- Jack McMullen - Simon Aspen
- Jack McMullen - Ethan Miles
- Keith Barron - Howard Coombes
- Keith Barron - Basil King
- Haruka Abe - Mika
- Karl Howman - Rod
- Adam Deacon - Tyrell Cater
- Adam Deacon - Jed Francis
- Oliver Hoare - Dean Marsh
- Oliver Hoare - Owen Lewis
- Matt Di Angelo - Tom
- Clive Wood - Tweedie
- Luke Pasqualino - Dans
- Gary Kemp - Matthew Merriman
- Gary Kemp - Michael Warwick
- Toyah Willcox - Hazel Tillier
- Reece Noi - Steve Baker
- Reece Noi - Marlon Miller
- Kelle Marie Walters - Dawn
- Kate Edney - Eve
- Derek Barr - Gareth
- Robyn Cooper - Anamaria
- James Gillan - Brandon
- Ellen Thomas - Florence Asike
- Ellen Thomas - Stephanie Mellor
- Alec Newman - Robert Ludlow
- Alec Newman - Craig
- Max Deacon - Joel
- Neve McIntosh - Eileen Naysmith
- Ariyon Bakare - Guy Trainer
- Maggie Steed - Sheila Toolan
- Tracy Shaw - Jane Farrell
- Don Warrington - Trevor
- Kenny Doughty - Steve
- Samantha Siddall - Katherine Finders
- Helen Mutch - Fran Chinton
- Leon Ockenden - Luke Riley
- Paul Oldham - Skip Carter
- Nabil Elouahabi - Suhail Haron
- Patricia Brake - Brenda Crowson
- John Alford - Taxi Driver
- John Alford - Dave Moore
- Danny Midwinter - Scott Cowden
- Danny Midwinter - Sgt Rains
- Amit Shah - Jake Milns
- Anthony Lewis - Joe Packard
- Anthony Lewis - Nate Brown
- Lynda Baron - Molly
- Laura Howard - Victoria Leach
- Laura Howard - Carly Swinford
- Laura Howard - Tania Sullivan
- Laura Howard - Eva Heggarty
- Laura Howard - Mary Barstow
- Laura Howard - Annie McQueen
- David Mallinson - The Dean
- Sean Hughes - Jimmy Shapleton
- Miffy Englefield - Amelia
- Julie T. Wallace - Registrar
- Julia St. John - Sarah Evans
- Mark Frost - Saul Doubleday
- Ron Moody - Chick
- Chris Fountain - Seb
- Pooky Quesnel - Pennie Ashton
- Pooky Quesnel - Emma Davies
- Andrew Sachs - Father Morgan
- Andrew Sachs - Mendel Lan
- Matthew James Thomas - Gary Yates
- Raymond Coulthard - Matt Strong
- Raymond Coulthard - Matt Stone
- Celyn Jones - Rob Hamley
- John Albasiny - Peter Everly
- Andrew Tiernan - Col Danvers
- Andrew Tiernan - O'Neill
- Richard Southgate - Chris Hallows
- Stephanie Beacham - Monica Shapiro
- Wendy Morgan - Denise
- Chris Evans - Himself (voice)
- Terence Maynard - Gary Linton
- Terence Maynard - Walter
- Michael Begley - Ian Dennis
- Jon Lee - Craig Robbins
- Georgia Henshaw - Maddy Devine
- Matthew Ashforde - Steve Devine
- Stephen Billington - Edward Thurlow
- Ciaran Kellgren - Cal McCoy
- Maurice Roëves - Carl Jackson
- Philip Jackson - Rob Royson
- Ameet Chana - Arun Sarin
- Amrita Acharia - Neela Sarin
- Linda Robson - Louise Costello
- Joseph Timms - Johnny Costello
- Michelle Collins - Camille Lewis
- Nathan McMullen - Devlan O'Connor
- Richard Hawley - Leslie Brant
- Josie Lawrence - Janet Haines
- Martin Delaney - Ben Chalmers
- Ruth Gemmell - Kate Margolin
- John Benfield - Albert Rossiter
- John Benfield - George Weaver
- Billy Seymour - Luke Hope
- Jack Bence - Karl Fontayne
- Karen Meagher - Coral Williamson
- Lewis Chase - Tommo Jameson
- Travis Oliver - James Molloy
- Jody Latham - Mikey Sandy
- Wendy Craig - Verity Lang
- Wolf Kahler - Alexander Chernov
- Lucien Laviscount - Liam Briggs
- Luke Tittensor - Stan Heyworth
- Matthew Kelly - Andrew Brookfield
- Jamie Harding - Ilan Al-Wahiri
- Cheryl Campbell - Miriam Turner
- Babou Ceesay - Jake Maddick
- Emma Cunniffe - Det Insp Joanne Collins
- Nathalie Emmanuel - Cheryl Hallows
- Beth Goddard - Hannah Fleet
- Siu Hun Li - Lei Kwok
- Chanel Cresswell - Liz Roberts
- Justin Salinger - Patrick Barton
- Danny Young - Kevin Brannigan
- Chetna Pandya - Rani Murad
- Denise Welch - Goldie
- Chris Ryman - Ash Murad
- Elliot Levey - Tim McCaffrey
- Kirsty Armstrong - Emily Firth
- Kaye Wragg - Maureen Firth
- Jonny Dixon - Brian Dennis
- Jonny Dixon - Carl Kamen
- Alan Ford - Norman Danvers
- Tina O'Brien - Chloe Trent
- Emma Samms - Rachel Greer
- Joe Duttine - Sgt Gary Poulter
- Joe Duttine - Frank Simons
- Reuben-Henry Biggs - Luke Mason
- Naomi Bentley - Annie McLean
- Frankie McLaren - Ciaran McNeive
- Taylor Jay-Davies - Rocco Slater
- Anabel Barnston - Maya Kemp
- Robin Kermode - Philip Kemp
- Eva Fontaine - DS Bain
- Angela Lonsdale - Helen Caffrey
- William Gaunt - Malc Stroud
- Oliver Stark - Kyle DeNane
- Susan Hampshire - Caitlin Northwick
- Matt Kennard - Chris Carey
- Anna Acton - Alex Scotton
- Phaldut Sharma - Damon Lynch
- Marshall Lancaster - Keith Parr
- Luke de Lacey - Patrick Farraday
- Billy Boyd - Duncan Jessup
- Sophie Ward - Sandra Dillon
- Andrew McNair - Dean Monroe
- Danny Dyer - Rossy
- Abigail Titmuss - Tara Edmonds
- Dominic Rickhards - Simon Brayford
- Robert Daws - Hugh Blakeley
- Ayden Callaghan - Mick Statham
- Nicola Posener - Leila Leyton
- Ed Birch - Frankie Joyce
- James Ainsworth - Kevin Granger
- Joe Sowerbutts - Jonas Wiley
- Clare Calbraith - Paige Norton
- Elizabeth Croft - Jessica Murray
- Stirling Gallacher - Ffion Morgan
- Stirling Gallacher - Michelle
- Dominic Mafham - Jerry Sands
- Dominic Mafham - Tyler MacKinnon
- Grahame Fox - DI Gavin Cook
- Toby Walton - Andy Haymer
- Emily Bruni - Sandra Wetherill
- Danny Webb - Martin Danton
- John Pickard - PC Chris Bidner
- Alex Esmail - Clint Jackson
- William Ash - Harry Reynolds
- William Ash - Kevin Eccles
- Tony Mooney - Rob Kamen
- Sacha Parkinson - Laura Bellamy
- Kazia Pelka - Sarah Phelan
- Ranjit Krishnamma - Mark Earl
- Tom Kane - Marcus Hillgrove
- Jane Slavin - Olivia Hillgrove
- Edward Wiley - Jonno
- Samuel Holland - Alan Thurlough
- James Alexandrou - Franny Da Vies
- Josh Brown - Darren Sullivan
- Jordan Bolger - Matt Conley
- Tom Szekeres - Stewart Byron
- Noah Hedges - Tyler Quinn
- William Rush - Stef Kelly
- Charlie Quirke - Danny Parks
- Lin Blakley - Maggie Coomes
- Francis Magee - Norris
- Gerard Rooney - Niall
- Paul Haigh - Keith Cassidy
- David Ross - Lenny Shines
- David Ross - Mr. Carnell
- Mark McGann - Joe Morrison
- Bradley Hall - Luke Parkson
- Thomas Craig - Graham Evans
- Alex Stedman - Jason
- Cathy Tyson - Cider Anne
- Kelli Hollis - Shelle Jones
- Nathan Clarke - Numar Hassan
- Jack Carr - Harry Taylor
- James Wilby - Archie Grayling
- Richard Huw - Simon Hackett
- Andrew Neil - Len
- Andrew Neil - Peter Winters
- Jon Laurimore - Ken
- Jordan Dawes - Will Franks
- Asif Khan - Aaron Richards
- Jenna Boyd - Rose Pearson
- Jenna Boyd - Carrie Malin
- Darren Tighe - Vince
- Darren Tighe - Jed Peterson
- Norman Pace - Harold Collins
- Ben Cartwright - Neil Denton
- Ben Cartwright - Liam Medford
- Ben Cartwright - Sgt Adrian Pitt
- Ben Cartwright - Felix Barstow
- Stuart Davidson - Dusty Builder
- Stuart Davidson - Prison Riot Officer
- Scarlett Rose Patterson - Nikki Munro
- Jessica Collins - Karen O'Grady
- Anne Stallybrass - Sheila Hocknall
- Jennifer Wilson - Lily Compton
- Philip Anthony - Dr. Phillips
- Clara Onyemere - Colette Jeffords
- Andre Fyffe - Hunter Jeffords
- Asmara Gabrielle - Pravi Lakhani
- Miranda Nolan - Lucy Short
- Anna Russell-Martin - Linda Aldridge
- Connor Catchpole - Richie Levy
- Connor Catchpole - Ryan Maberley
- Alice Sykes - Amber Kensit
- Cat Simmons - PC Andrea Mills
- Gwydion Rhys - Shaun Butler
- Harry Gilby - Toby Williams
- Yinka Awoni - Wallace Jamerson
- Georgia Landers - Elizabet 'Libby' Sharpe
- Christine Pritchard - Edna Bryant
- Leon Harrop - Jordan 'Jordy' Holt
- Lizzie Roper - Claire Holt
- Eugene Collins - Lamar Lowell
- Shaun Thomas - Bruno Wilding
- Sharlene Whyte - Javine 'Jay' Adams
- Conrad McCroddan - Simon Tierney
- Shobu Kapoor - Mona Nadkarni
- Lloyd Meredith - Bradley Gibbins
- Laurie Brett - Gail Donham
- David Ganly - Trevor Donham
- Bamshad Abedi-Amin - Douglas 'Dougie' Whitehouse
- Ashley Gerlach - Victor Clemens
- Abhin Galeya - Ajay Singh
- Philip Wright - Graham Kirkby
- Joey Phillips - James Kershaw
- Victoria Myers - Marie Kershaw
- Lily Knight - Tara Reynolds
- Emily Redpath - Ashlee Watkinson
- Chris Gordon - Ross West
- Clara Indrani - Mrs Yasmin Kirmani
- Katy Stephens - Shannon Sutby
- Neal Barry - Malcolm 'Mal' Duskley
- Cameron Jack - James 'Jimmy' Barnett
- Douglas Rankine - Mark Johnstone
- Ben Allen - Avery Hicks
- Scott Mills - TV Reporter - Paul Lang
- Scott Mills - DJ
- Pete Gallagher - Danny Toms
- Saskia Ashdown - Nicole ‘Nikki’ Merrow
- Corinne Skinner-Carter - June Jackson
- Corinne Skinner-Carter - Mrs. Johnson
- Corinne Skinner-Carter - Ellen Weekes
- Charles Dale - Big Mac
- Adam Sina - Marcus Fidel
- Brendan Charleson - Clive Delmore
- Nohail Nazir Mohammed - Amir Bashar
- Olwen Rees - Bridget Nyman
- Rhian Morgan - Molly Torrell
- Katie Brayben - Lisa Fernham
- Harry Long - George Corsham
- Edyta Budnik - Zosia Nowak
- Jean Trend - Doris Parry
- Bobby Lockwood - Leon Cook
- Maggie O'Neill - Cindy Cooper
- Rupert Vansittart - Kenneth Stair
- Zoë Watson - young Roberta
- Raji James - Adil Saifi
- Rebecca Hesketh-Smith - Millie Hayford
- Brian Bovell - Gaz Jones
- Brian Bovell - Jed
- Dafydd Emyr - Chairperson
- Caroline O'Neill - Jane Cormett
- Rick Warden - Ciaran Coulson
- Sanna Kelly - Mary
- Fisun Burgess - Bibi Kirkby
- Geff Francis - Tony Afolami
- Kelly Clare - Nia Amberson
- Ashley Margolis - Owen Robeson
- John Cording - Sid Thorman
- Leslie Ash - Vanessa Lytton
- David Hounslow - Brian Kuller
- Shannon Hayes - Jeannie Cotler
- Bill Ward - Mike Sartwell
- Tom Mulheron - Luka Malinovsky
- Dermot Canavan - Tom Burich
- Lollie McKenzie - Natalia Malinovsky
- Danny Szam - Xander Hayes
- Alexei Sayle - Anton Malinovsky
- Huw Euron - Sgt. Gerard Wilson
- Luke Nunn - Neil Shotts
- Jennifer Matter - Eliza "Liza" Henard
- Julie Barclay - Sandra Boen
- Jack Stewart - Elijah 'Eli' Kenton
- Narinder Samra - Pen Khatri
- Alison Dowling - Ashley Khatri
- Joseph Tweedale - Crosby
- Cecilia Noble - Lucy Afolami
- Sam Callis - Albert 'Big Al' Layne
- Stevie Raine - Alan 'Al' Shepton
- Bianca Bardoe - Kate Dunlay
- Jacob Greener-Tofts - Riley Dale
- Sophie Stone - Susie Ashby
- Freddie Rose - Damon Wagstaff
- John Webber - Dr. Roe
- Anna Niland - Ellen Jones
- Martin Walsh - Nick Maberley
- Rosalind March - Elissa Saint
- Halema Hussain - Farah Bakshi
- Rebecca Calienda - Lauren 'Ren' Kearn
- Howard Ward - Don Kearn
- El Anthony - Craig Fernsby
- Patrick Godfrey - Derick Tome
- Jediael Stiling - Kyle Morgen
- Simone Saunders - Holly Cage
- Nicole Arumugam - Maureen 'Mo' Ramson
- Jordan A. Nash - Young Kyle Morgen
- Paul Popplewell - Paul Pegg
- Tasha Lim - Bailey Chan
- Tasha Lim - Marika Hobart
- James Barriscale - Brian Godard
- Jonny Green - Joseph 'Joe' Walcotts
- Alhaji Fofana - Solomon 'Sol' Mathes
- Alex Austin - Luke Reynolds
- Georgia Clarke-Day - Maja Christovel
- Dee Ahluwalia - Isaac Bryden
- Richard Shackley - Security Guard
- Mark Letheren - Dave Grazer
- Michael Gould - Tony Gerrard
- Rosie Jones - Paula Kettering
- Zainab Hasan - Hafsa Kazimi
- Maanuv Thiara - Chauncey Myer
- Holly Aird - Laura Merriman
- Kriss Dosanjh - Ashok Masum
- Molly Wright - Rosie Kemper
- Raj Bajaj - Adith 'Adi' Kapadia
- Hara Yannas - Carla Roswell
- Katie Sheridan - Becky Eastwood
- Jo Martin - WDS Bridgeman
- Jo Martin - Vicky Lambert
- Jo Martin - Max McGerry
- Rukku Nahar - Rosa Sarwar
- Ella Balinska - Susie Barbour
- Rose Ayling-Ellis - Bianca Sinclair
- Rosie Taylor-Ritson - Nerys Driscoll
- Alice Henley - Chrissy Pearson
- Kelly Marcel - Vicky Morris
- Regé-Jean Page - Daniel Kimpton
- Jay Saighal - Kieran Lightburn
- Jay Saighal - DC Mahmoud Laghari
- Simone Ashley - Shai Anderton
- Robert Ryan - Patient
- Oscar Wallwork - Will Milbury
- Kit Connor - Barnaby Lee
- Rebecca Root - Psychiatric SHO
- Alistair Brammer - Jack Diamond
- Joshua McCord - Frank Delmore
- Joshua McCord - Lewis Rudd
- Josh Taylor - Dom Harcombe
- Tom Maguire - Tim Jenkins
- Katie Clarkson-Hill - Fern Cross
- Imogen Faires - Tilly Matthews
- Rod Hallett - PC Harry Sinclair
- Amanda Ryan - Mel Sinclair
- Leanne Henlon - Mags Wilson
- Jonathan Delaney Tynan - Eoghan Nash
- Danielle Phillips - Hayley McDonnell
- Dan Mersh - Sam Williams
- Michael Moreland - Matthew Levy
- Mary Jo Randle - Samantha Hardy
- Aretha Ayeh - Riley Camilleri
- Fiz Marcus - Cynth Paretsky
- Kathryn Georghiou - Jessie Floyd
- Arinder Sadhra - Uma Mehta
- Sani Thabo - Abe Burrows
- Kane Surry - James Woodward
- Carolin Stoltz - Lucy Mumby
- Benjamin Fisher - Nick Mumby
- Brett Allen - Rick Phillips
- Jordan Coulson - Woody Doyle
- Ellie Goffe - Candy Brooke
- Natalie Spence - Abi Rippen
- Al Nedjari - Yannick Abadi
- Tariq Rasheed - Aadi Mehta
- Dainton Anderson - Noah Halliday
- Janie Booth - Irene McKenna
- Declan Rodgers - Lewis Halliday
- Lynn Hunter - Anna Fitzpatrick
- Corey Montague-Sholay - Kofi Opoku
- Amanda Walker - Brenda Tome
- Amanda Walker - Tianna Rustin
- Daniel Watson - Matt Halliwell
- Alina Allison - Tabby Burke
- Jack Gouldbourne - Jimo Armstrong
- Rameet Rauli - Neha Kapoor
- Varun Raj - Nikhil Kapoor
- Stephen Kennedy - Adam King
- Joe Sproulle - Liam Sanderson
- Daniel Davids - Mark Foster
- John Rogers - Jordan Wicks
- David Sterne - Geoff Cole
- Doyin Ajiboye - Mia Almada
- Sarah-Jane Holm - Sheena Holdman
- David Omordia - Omari Simm
- Aaron Shosanya - Mpho Simm
- Keith Bartlett - Alfie Gordon
- Freddie Dawson - Oskar West
- Adrianna Bertola - Sharice Brooks
- Adrianna Bertola - Sharice
- Adrianna Bertola - Jessie Palmerston
- Chris MacDonald - Tom Porter
- George Sargeant - Lachlan Daniels
- Paislie Reid - Yaz Darwish
- Gemma Dyllen - Morgan Alexander
- Helen Belbin - Alice Redfield
- Robin Berry - Tyler Winterson
- Fiona Rodrigo - Dr Shah
- Tres Hanley - Meg Koprowski
- Tim Treloar - David Patterman
- Katie Kerr - Creche Manager
- Kirsty Malpass - Grace Balkin
- Daniel Hoffmann-Gill - Daniel Balkin
- Paddy Navin - Bev Smithson
- Steve Garti - Grant Nelson
- Amy Chung - Suze Chen
- Paddy Wallace - Ralph Bell
- Gwion Glyn - Benji Watts
- Ben Walton-Jones - Sonny Davies
- Hebe Beardsall - Kim Meadows
- Mia Jenkins - Laura
- Karlina Grace-Paseda - Katie Bartlett
- Carrie Crowley - Bridge Carroll
- Carla Langley - Niamh Carroll
- Nicholas Woodeson - Jack Clayton
- Hemi Yeroham - Yanko Akbash
- Lowri Izzard - Amy Bishop
- Libby Hall - Lena Simenon
- Melanie Gutteridge - Emma Bower
- Jessica Johnson - Kelly Jackson
- Xavien Russell - Levi Jackson
- Avita Jay - Cat Turing
- Mark Arends - Declan King
- Nia Gandhi - Penny Walsh
- Simon Bubb - Hardy Walsh
- David Nellist - Arthur Spicer
- Simon Sherlock - Owen Mickelthwaite
- Nick Harris - Lennie Parkes
- Natalia Kostrzewa - Ange Koceski
- Catherine Hamilton - Ellie Burton
- Jonathan Watson - Vince Whitby
- Leila Mimmack - Anya Whitby
- Samila Kularatne - Fatima Bashara
- Jonathan Nyati - DI Willet
- Akshay Shah - Josh Warren
- Misha Butler - Robert Calvert
- Sadie Pickering - Denise Hatchman
- Miranda Howard-Williams
- Diarmuid Lawrence
- Ian Barnes
- Jennie Paddon
- Ruth Carney
- Alan Wareing
- Sam Snape
- Kellie Smith
- Ashley Pharoah
- Barbara Machin
- Colin Bytheway
- Poz Watson
- Lou Prendergast
- Sarah Beardsall
- Nikki Wilson
- Dafydd Llewelyn
- Debbie Shewell
- Rebecca Hedderly
Sophie Okonedo interpreta a Gina Russell en la serie.
Shirley Henderson interpreta a Denise en la serie.
Billy Boyd hace el papel de Duncan Jessup.
Maurice Roëves interpreta a Carl Jackson en la serie.
Pete Postlethwaite interpreta a Hank en la serie.
Marina Sirtis interpreta a Jane Taylor, MP en la serie.
Alan Ford interpreta a Norman Danvers en la serie.
Adrian Rawlins hace el papel de Richard Thomas.
Orlando Bloom interpreta a Noel Harrison en la serie.
Eddie Marsan hace el papel de Rick Grant.
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