- Tom Kenny - Mr. Molesby / Moles (voice)
- Carlos Alazraqui - Giant Snake (voice)
- Laraine Newman - Greta (voice)
- Harland Williams - Thomas Edison's Ghost / Alien (voice)
- Chad Doreck - Colt Bifton (voice)
- Joe J. Thomas - Pa Rabbit (voice)
- Carl Lumbly - Lead Prison Guard / Vampire Bat (voice)
- Daran Norris - Agent 51 (voice)
- Sonya Leslie - Queen Shelia (voice)
- Sonya Leslie - Queen Sewariel (voice)
- Rick Zieff - General Cashews (voice)
- Yuri Lowenthal - Zakarov (voice)
- Donovan Patton - Putt-Putt Pete (voice)
- Max Mittelman - Genie (voice)
- Patrick Seitz - Zogthoth (voice)
- Patrick Seitz - Treegor (voice)
- Fred Tatasciore - Count Orlock (voice)
- Fred Tatasciore - Chaos (voice)
- Gail Bean - Tabitha (voice)
- Robert Catrini - Rat Pack Boss (voice)
- Jasmine Kaur - DJ Demon (voice)
- Will Friedle - Captain Science Magic Love (voice)
- P.J. Byrne - Boogaloo (voice)
- David Shaughnessy - Harold's Tail (voice)
- Steve Blum - Cat Shaver (voice)
- Steve Blum - Marvin the Ghost (voice)
- Roger Craig Smith - Party Animal (voice)
- Trevor Devall - Lucky Cricket (voice)
- Shaunt Nigoghossian
- Maxwell Atoms
- Drew Neumann
- Paul E. Francis
Sean Astin interpreta a Chester (voice) en la serie.
Brian Kimmet interpreta a Harold (voice) en la serie.
Chris Kattan hace el papel de Bunnicula / Mina's Dad (voice).
Kari Wahlgren hace el papel de Mina (voice).
Eric Bauza interpreta a Patches the Weredude (voice) en la serie.
Richard Steven Horvitz interpreta a Lugosi (voice) en la serie.
Capítulo disponible en las siguientes plataformas:
