- Ryan Sampson - Thomas 'Tommo' Schaffner
- Dominic West - Dr. Chris Coxley
- Ramon Tikaram - Terence McCann
- Anthony Welsh - Jake
- Ruth Sheen - Kath
- Tadhg Murphy - Gary
- India Mullen - Samantha
- Niamh Cusack - Clodagh
- Neil Ashton - Davey MacDonagh
- Muzz Khan - Adyan Khan
- Camille Cottin - Fiona Frank
- Bhavna Limbachia - Meena
- Bhavna Limbachia - Bridezilla
- Jude Riordan - Tyler Croft
- Mali Harries - Babs
- Tom Bennett - Ringo
- Paul Green - Walter
- Raad Rawi - Eric Nosh
- Julie Barclay - Sergeant
- Brendan Purcell - Man (Petrol Station)
- Saabeah Theos - Amelia
- Daniel Lloyd - Cop
- Steve Garti - Chinese Dan
- Amit Dhut - Calvin
- Lisa Whiteside - Jackie Carr
- Nick Holder - Wayne Carr
- Archie Kelly - Shirley 'Goldilocks' Paslowski
- Neil Fitzmaurice - Mr Bishop
- Mark O'Halloran - Francis
- Nick Harris - Graham
- Dominic Coleman - Geoff
- Joseph Mydell - Wood Dweller
- Tim Paley - Security Guard
- Rachid Sabitri - Manolito
- Ruth Madeley - Clara Marie
- Hylton Collins - Man in the Van
- Felipe Pacheco - Jason
- Emmanuel Berthelot - Codrin
- Leon Harrop - Albie
- Saida Ahmed - Linda
- Magnus Bruun - Bodyguard - Oskar
- Darci Shaw - Amy Croft
- Lewis Reeves - Keenor
- Sandra James-Young - Pammy
- David Weiss - Business Man
- Steve Pemberton - Mr King
- Zoe Telford - Mrs King
- Paul Foxcroft - Professor Edwards
- Neven Pilipovic - Howard
- Adam Ewan - Father Paul
- Jonny Cordingley - Dr White
- Hubert Hanowicz - Alexi
- Alan French - Lance Fallon
- Amer Nazir - Mo
- Rory Gallagher - Foz
- Tim Dantay - Vinnie's Dad
- Michelle Wen Lee - Jihan
- Darren Jeffries - Mini Mart Owner
- Martin Reeve - Gerald
- Jeffrey Ho - Ah Long
- Javed Haider - Neighbour
- Gemma Merna - Neighbour's Wife
- Paislie Reid - Lisa
- John Weaver - Carl Slater
- Chris Lew Kum Hoi - Hoskins
- Felicity Montagu - Lesley Anne
- Maanuv Thiara - Reggie the photographer
- James Warrior - Ernie
- Andrew Dawson - Lad
- Andrew Dawson - Kurt
- Neil Hurst - Prison officer
- Laura Checkley - Ruth
- Lucy Trodd - Female guard
- Will Graham - Vernon
- Kiruna Stamell - June
- David Howell - Brian Kennerley
- David Pearse - Doolan
- Simon Naylor - Bouncer
- Perry Moore - Squirrel
- Debbie Rush - Mrs Bishop
- Steven Hartley - Russell Hardwick
- Juliet Cowan - Liz Jones
- George Potts - Harold Pipsky
- Gareth Cassidy - Speed Date Man 4
- Baga Chipz - Beautiful Lady
- Divina De Campo - Beautiful Lady
- Carl Rice - Ronnie Croft
- Darren Cahill - Mick Dennings
- Gerard Jordan - Niall Dennings
- Johann Myers - Auntie Pat
- Ian Curley - Cook
- Steven Hillman - Barman #1
- Lizzie Hopley - Andrea
- Neil Bell - Keithy
- Seamus O'Neill - Site Foreman
- Jordan Williams - Handsome Lumberjack
- Jyuddah Jaymes - Tuma
- Oghenekevwe Emefe - Hen
- Lucy Russell - Lady Beverly
- Barry Aird - Glover
- Curtis Cole - Demolition Worker
- Leon Delroy Williams - Voodoo Ray
- John McGrellis - Grabbe
- Daniel Coll - Geoff
- Craig Cheetham - Gun Man
- Dennis Blanch - Ralph
- Tim Key - Vortex
- Dan Starkey - Glen Glenson
- Melanie Kilburn - Brenda
- James Puddephatt - Van Driver
- Deirdre Donnelly - Mo Dennings
- Francis Magee - Big Joe Blane
- Jack Holden - Traveller Boy
- Joe Egan - Referee
- Paddy C Courtney - Paddy
- Naomi Yang - Dr. Nicola Jones
- Rick S. Carr - Joe Blane Jr
- Hugh Simon - Uncle Mervin
- Maxine Burth - Aunt Vanessa
- Glenn Cunningham - Fish Buyer
- Alex Lowe - Tinsley Blanchett
- Jennifer James - Leonie
- Lindsay Stanger - Police 1
- James Lewis - Police 2
- Anna Acton - Lydia McCann
- Josh Moran - Sly Si
- Claude Scott-Mitchell - Sara
- John Thomson - Colin Popov
- Dave Galbraith - Kenny Diamond
- Stephen McCole - Nathan Beasley
- Antony Somers - Knife Thrower
- Bill Paterson - Tony Tillerton
- Stella McCusker - Alma
- Jarreau Benjamin - Masked Man
- Ben Hackett - Young Vinnie
- Oliver Wellington - Aaron
- Jeff Rawle - Mister Bates
- Andrew Readman - Mr Cooper
- Linda Hargreaves - Vanessa
- Leo Atkin - Mr Roberts
- Andrew Whitehead - Security Guard
- Michelle Parker - Jules
- Jason Lamar Ricketts - Jason
- Jason Lamar Ricketts - Prison guard
- Ed Gaughan - Gideon
- Olwen Fouéré - Margaret
- Toby Gaffney - Sara's Dad
- Wayne Cater - Steff Styles
- Nikhil Parmar - Steven McCann
- Nikhil Parmar - Stephen McCann
- John Tueart - Cop 1
- Joe Simpson - Desk Sergeant
- Mia Crossley - Girl 1
- Simone Holmes - WPC
- Adam Foster - Dad
- Ethan Lawrence - Louis
- Cassie Vallance - Mum
- Hannan Ahmed - Sarim
- Lee Mack - Eddie Braithwaite
- Steve Furst - Jim Bowen
- Christopher Beck - Arthur
- Greg Wood - Barry MacDonagh
- Sam Glen - Martin Jobsworth
- Samantha Power - Donna MacDonagh
- Darwin Taylor - Trucker
- Darwin Taylor - Mike
- Adam Shaw - Three Eyed Pete
- Howard Ward - Leo
- Olwen May - Margaret
- Gary 'Mani' Mounfield - Mani
- Tony Nyland - Specky Sid
- Tony Nyland - Specky Kid
- Chris Hoyle - Neil Croft
- Amy Blake - Teenage Girl
- Tom Bell - Priest
- Flo Wilson - Lavender
- Louis Emerick - Billy Baileaf
- Helen Sheals - Betty Baileaf
- Donna Preston - Julie
- Gene Gurie - Robbo
- Dean Lennox Kelly - Curtis Plum
- Shobna Gulati - Gina
- Sarah Madigan - Dervla
- Annette Badland - Rhoda
- Iona Mckeown - Bridesmaid
- Jasmine Kerr - Geri
- Tachia Newall - Callum
- Alexandra Maxwell - Lorraine
- Caroline Chesworth - Lucinda
- Katherine Dow Blyton - Geraldine
- Samantha Robinson - Midwife
- Mushi Noor - Art Restorer
- Matthew Khan - Receptionist
- Dan Renton Skinner - Phil Brilliance
- James Quinn - Maurice
- Cathy Breeze - Prim Mum
- Miles Higson - Sandwich Man
- Robert Calvert - Uncle Eldon
- Paul Tylak - Mardie Fisher
- Michael Glenn Murphy - Don Randy
- Flaminia Cinque - Mrs Calvo
- Bijan Daneshmand - Mr Calvo
- Sebastian Emmerson - Petrol Cashier
- Mat Wright - Daniel (Sales Rep)
- Nick Harris - Graham
- Claire De Boer - Juanita
- Stevie Raine - PC Stevens
- Joseph Steyne - Manolito's Bodyguard
- Josh Bolt - Elvis
- Mark Sheals - Tough Looking Man
- Liza Tarbuck - Beatrice
- Tareq Al-Jeddal - Spotty Assistant
- Dylan Baldwin - Joey Kittens
- Alex Carter - Byron
- George Somner - Scott
- Paul Kemp - Jon
- Judith Alexander - Judith
- Jim Whelan - Old Man
- Elizabeth Berrington - Paloma
- Simon Hepworth - Glen
- Jason Done - Keith
- Martine Brown - Kim Ratcliffe
- Tony Hirst - Dougie Ratcliffe
- Adam Fogerty - Dusty Glazer
- Ashley Margolis - Colin
- John-Luke Roberts - Registrar
- Chelsea Edge - Kara
- Jack Brady - Ian (Dylan's Father)
- Farrel Hegarty - Hayley Carver
- George Appleby - Donny
Capítulo disponible en las siguientes plataformas:
