- Alison Sealy-Smith - Nurse Lydia
- Keon Alexander - Sri
- Keon Alexander - Sri (uncredited)
- Michael Mando - Dr. Manolas (uncredited)
- Michael Mando - Dr. Manolas
- Joe Cobden - Zoltan
- Byron Lawson - Karl
- Richard Tse - Ming’s Father
- Terra Vnesa - Sienna
- Ingrid Veninger - Maria
- Ingrid Veninger - Maria (uncredited)
- Paula Rivera - Niki
- Stuart Hughes - Dr. Norby
- Tony Nappo - Bobby Dizon
- Zoie Palmer - Female Cop
- Maurice Dean Wint - Anatomy Lab Professor
- Marcia Bennett - Mrs. Amin
- Marilla Wex - OB Nurse
- Alex House - Todd
- Andrea Davis - Paramedic
- Mike McPhaden - Mr. Santorini
- Joan Massiah - Mrs. Withrow
- Amber Cull - Triplet's Mom
- Kiran Friesen - Katja
- James Gangl - Fitz's Patient
- Angela Vint - Mrs. Sanger
- Scott Yaphe - Mr. Sanger
- Gia Sandhu - Samar
- Fuad Ahmed - Khaled (as Gabriel Grey)
- Natalli Reznik - Russian Girl
- Rishma Malik Scott - Mrs. Singh
- Rishma Malik Scott - Mrs. Singh (uncredited)
- David Reale - Student in Bar
- Nick Abraham - Chen's Patient
- Shawn Campbell - Lou
- Stephen McHattie - Dr. Standish
- A. Frank Ruffo - Mr. Dizon
- Rick Sood - Mr. Singh
- Daniel DeSanto - Steven Dizon
- Bathsheba Garnett - Mrs. Goldberg
- Ivan Sherry - Ralph
- Danny Waugh - Orderly
- Maria del Mar - Dr. Miniadis
- Maria del Mar - Dr. Miniadis (uncredited)
- Kristopher Turner - Winston
- Julia Chan - Adrianne
- ??? - Grandfather
- Brendan Penny - Claude
- Stefanie Drummond - Admissions Nurse
- Stefanie Drummond - Kara
- Gage Munroe - Devil Child
- Dan Lett - Jim McBride
- Greg Ellwand - Mr. Fitzjohn
- Nahanni Johnstone - Mrs. Fitzjohn
- McKenzi Scott - Australian Nurse
- Laurie Ma - Ming's Cousin
- Linlyn Lue - Herbalist
- Jamie Ferenczi - Nurse / Receptionist (uncredited)
- Stefen Rollpiller - Tomas Wilhelm (uncredited)
- Stefen Rollpiller - Tomas Wilhelm
- William Ellis - Eli
- Justin Mader - Male Cop
- Irene Pauzer - Mrs. Wilhelm
- Vincent Lam - Mr. Needle
- Julie Sype - Salon Employee
- Kim Roberts - Nurse Ronai
- Tatiana Maslany - Janice
- Debra McCabe - Mrs. Miller (as Debra Lynne McCabe)
- Paolo Mancini - Oliver
- Rodrigo Fernandez-Stoll - Airport Soldier
- Brad Borbridge - Dr. Pielou
- Sharlene Royer - Worried Mothet
- Jemini Archer - Young Patient
- Marianthi Evans - Ming's Mother
- Kathryn Haggis - Adoption Examiner
- Chick Roberts - Concerned Man
- Camden Angelis - Judy (uncredited)
- Thomas Hauff - Priest
- Noah Dalton Danby - Jeff Goodes (as Noah Danby)
- Sandra Forsell - Debbie Goodes
- Ayesha Mansur Gonsalves - Resident (as Ayesha Mansur)
- Rachel Talalay
- Erik Canuel
- Kari Skogland
- Gail Harvey
- Vincent Lai
- Jason Sherman
Kim Roberts interpreta a Nurse Ronai en la serie.
Stephen McHattie interpreta a Dr. Standish en la serie.
Byron Mann hace el papel de Chen.
Mayko Nguyen interpreta a Ming en la serie.
Shawn Ashmore interpreta a Fitz en la serie.
Kim Bubbs interpreta a Sharon en la serie.
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