- F. Murray Abraham - Cyril
- Elisabeth Röhm - Dana Landon
- Jack Murray - Security Guard
- Anthony Ruivivar - Agent Henry Knox
- Geoffrey Blake - FBI Special Agent Brian Hendricks
- Melissa Tang - Grace Rose
- Jay Ali - Crown Prince Sheikh Abu
- Natalie Krill - Dr. Paretti
- Khaira Ledeyo - Vanessa Chandler
- Karen Cliche - Agent Kerry Duffy
- Jake Manley - Derek Moore
- Zach Appelman - Alton Finn
- Pat Mastroianni - Agent Russo
- Marcia Bennett - Mrs. Potts
- Max Schneider - Jake Riley
- Michael Filipowich - Omar
- Emily Swallow - Belinda Zalman
- AnnaLynne McCord - Dianne Vaughn
- Kearran Giovanni - Miranda Bishop
- Ipsita Paul - Agent Simkins
- Laura Cilevitz - Sue
- Anthony J. Mifsud - Scratch
- Blair Redford - Zach
- Jenn Proske - Clarissa
- Pawel Szajda - Vlad
- Christopher Heyerdahl - Dr. Nicholas Markus
- Rob Stewart - Mr. Chandler
- Rob Stewart - Mr. Chandler (uncredited)
- Sean Baek - Franklin Lewis
- Martin Roach - Lieutenant Tran
- Annie Murphy - Amy
- Kaniehtiio Horn - Octogon Fighter (as Tiio Horn)
- Morgan Kelly - Detective Philmore
- Lara Jean Chorostecki - Iris
- Wendy Crewson - Helen Ellingsworth
- Kimberly-Sue Murray - Lola Lang
- Peter Outerbridge - Silverfox
- Peter Outerbridge - Silverfox (uncredited)
- Jess Salgueiro - Patsy
- Charlotte Arnold - Marissa Zane
- Emily Piggford - Lab Tech
- Don McCutcheon
- Deborah Chow
- David McLeod
- Norma Bailey
- Fred Gerber
- Steven A. Adelson
- Gillian Horvath
- Vanessa Rojas
- Amy Curen
- Jeff Rake
- John A. Norris
- Eric Tuchman
- Flume
Kristin Kreuk interpreta a Catherine Chandler en la serie.
Jay Ryan interpreta a Vincent Keller en la serie.
Nina Lisandrello interpreta a Tess Vargas en la serie.
Austin Basis hace el papel de J.T. Forbes.
Nicole Gale Anderson interpreta a Heather Chandler en la serie.
F. Murray Abraham interpreta a Cyril en la serie.
Capítulo disponible en las siguientes plataformas:
