- Larry Manetti - Bob Boyle
- Jeff MacKay - Donald French
- John Lawlor - Jim Reese
- James Murtaugh - Medical Lieutenant
- John Durren - Doc Roberts
- Charles Napier - Red Buell
- Jake Mitchell - Robert Boyle
- Janice Carroll - Nurse Delmonte
- Sandra Kerns - Nurse
- Byron Morrow - Adm. Nimitz
- James Carroll - Admiral's Aide
- Peter Donat - Col. Mathis
- Sharon Gless - Nurse 1st Lt.
- George Gaynes - Claire Lee Chennault
- Lance LeGault - Lt. Huck
- Anthony Charnota - Freddy
- David Roya - DeSoto
- Richard Bruce Doughty - Tom Buell
- Robin Riker - 1st Nurse
- Sharmagne Leland-St. John - 2nd Nurse
- Curtis Credel - Navy Lieutenant
- Pat Skelton - Hamilton
- René Auberjonois - Matthew Hooper
- Lloyd Kino - Japanese Captain
- Hatsuo Uda - Japanese Sentry
- Dale Ishimoto - Japanese Mechanic
- Donald Petrie - 1st Lt. Doug Rafferty
- Richard Rasof - 1st Lt. Deke Stubbins
- Phillip Simms - Squim
- Frank Parker - Commander
- Walt Davis - Sergeant
- Tim Haldeman - Sailor
- Jeb Stuart Adams - Lt. Jeb Pruitt
- Harry Fleer - General Douglas MacArthur
- Tom Fitzsimmons - 2nd Lieutenant
- Bill Fletcher - Commander Pritchett
- Robert Clarke - Admiral Frank Grayson
- Kent McCord - Capt. Charles W. Dobson
- James Hong - Col. Ikuda
- Norman Burton - General Carl Gant
- Robert King - Japanese Sub Captain
- James Darren - Lt. Col. Rod Towers
- Anne Francis - Lt. Cmdr. Gladys Hope
- Read Morgan - Mechanic
- Philip DeGuere Jr.
- Stephen J. Cannell
- Peter Carpenter
- Mike Post
Kent McCord hace el papel de Capt. Charles W. Dobson.
Robert Conrad interpreta a Greg "Pappy" Boyington en la serie.
Simon Oakland interpreta a Thomas Moore en la serie.
Dana Elcar interpreta a Thomas A. Lard en la serie.
Dirk Blocker interpreta a Jerry Bragg en la serie.
W.K. Stratton interpreta a Larry Casey en la serie.
Robert Ginty interpreta a T.J. Wiley en la serie.
John Larroquette interpreta a Bob Anderson en la serie.
Joey Aresco interpreta a John "Hutch" Hutchinson en la serie.
Larry Manetti interpreta a Bob Boyle en la serie.
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