- William Gaminara - Will Newman
- Julia-Lee Smith - Kerry
- Sally Rogers - Yvonne Harper
- Karl Shiels - Patrick Deely
- Amelia Bullmore - Lin
- Andrew Buckley - Tad
- Sandy Welch - Sawyer
- Helen Pearson - Mrs Atkins
- Amanda Haberland - Pippa
- Slim - Stand-up Comic
- Razaaq Adoti - Olly
- Sheila Whitfield - Jas
- Felicity Dean - Alice
- Orla Charlton - Ann
- David Crow - Phil
- Paul Whitby - Rick
- Lucy Trodd - Claire
- Joe Caffrey - Matt
- Kenneth Hadley - Dick Wallace
- Myriam Acharki - Kitten
- Paula Jacobs - Rosa
- Indira Varma - Sacha
- Indira Varma - Sasha
- Steve Jameson - Sid
- Robin Pearce - Joel
- Richard Zajdlic - Photocopier Man
- Emma Pike - Maggie
- Nigel Hastings - Andrew Jefferson
- Hugh Simon - Phil Tatchell
- James Barriscale - Danny McCowan
- Angus Wright - Ed Viner
- David Sibley - Joe Walsh
- Keir Charles - Dan
- Keir Charles - Daniel
- Gerrard McArthur - Kieran
- Shelley Conn - Carrie Knowles
- Jonathan Kemp - Alistair Price
- Indra Ové - Tyler Clarkson
- Stevie Allen - Nick
- Christine Entwisle - Ren Spencer
- Chloe Bailey - Jessica
- Allison McKenzie - Alison
- Paul Albertson - Mark
- Michael Fenton Stevens - Tim
- Sally Edwards - Maxine
- Natasha Cashman - Rebecca
- Steve Money - Fat Chas
- Janine Wood - Carol
- Craig Parkinson - Darren
- Rachel Scorgie - Claire
- Judi Shekoni - Sue
- Rebecca Gethings - Ruth
- Stuart Bowman - Steve
- Nabil Elouahabi - Kev
- Amber Sealey - Teri McLean
- Lynn Farleigh - Dr Heather Green
- Andy Pointon - Joel
- Tim Preece - David
- Caroline Loncq - Charlotte Webster
- Leo Bill - Matt
- Tom Turner - Simon
David Walliams interpreta a Jake Plaskow en la serie.
Julia-Lee Smith hace el papel de Kerry.
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