- Drew Fuller - Trevor LeBlanc
- Kelli Williams - Jackie Clarke
- Alyssa Diaz - Gloria
- Caroline Day - Emmalin Holden
- J. J. Soria - Hector Cruz
- Kim Allen - Amanda Joy Holden
- Torrey DeVitto - Maggie Hall
- Richard Bryant - Jeremy Sherwood
- Ashanti - Latasha Montclair
- Elle McLemore - Holly Truman
- Brooke Shields - Kat Young
- Erin Krakow - Tanya Gabriel
- Paul Wesley - Logan Atwater
- Burgess Jenkins - Eddie Hall
- Jesse McCartney - Tim Truman
- Brant Daugherty - Patrick Clarke
- Jeremy Davidson - Chase Moran
- Jeremy Davidson - Chase Moran (uncredited)
- Seamus Dever - Dr. Chris Ferlinghetti
- Kellie Martin - Nicole Galassin
- Ella Wahlestedt - Caroline Hall
- Bryan Chatlien - LT Walker
- Tonya Pinkins - Viola Crawford
- Matt Lintz - Chris
- Mark LaMura - Nigel Miller
- Darby Lynn Totten - Margo
- Renier J. Murillo - Ricardo Martinez
- Clifton Powell - Terrence Price
- Anthony K. Hyatt - SFC Hank Loman
- Yaya DaCosta - Specialist Amber Stiles
- Michael Nouri - General Ludwig
- Albert Jones - Major Brian Russo
- Jake Johnson - Lucas
- Jeff Rose - Major Ogden
- Rhoda Griffis - Lenore Baker Ludwig
- Rhoda Griffis - Lenore Baker
- Jon Chaffin - Eric Belton
- Maria Howell - Major Barcenilla
- Danny Vinson - Agent Chapman
- Valerie Payton - Patty Fellows
- Phillip DeVona - SFC Larson
- Phillip DeVona - SSG Larson
- Ramsey Faragallah - Sheik Jaffar Al-Kahlid
- Richard L. Fister - Sergeant Major (uncredited)
- Anthony Osment - Soldier (uncredited)
- Laila Robins - Grace
- Gina Rodriguez - Marisol Evans
- Sharon Conley - Alicia
- Ariel Shafir - Abu Al-Ahmed
- Cullen Moss - Danny Farina
- Lynn Cole - Irma
- Vivian Fleming-Alvarez - Mrs. Martinez
- Maxwell Terlecki - Billy
- Samuel Whitten - Pete Evans (uncredited)
- Victoria Cartagena - Carmen Richards
- Wesley Murphy - Scott Keyes
- Eric Goins - Jeff Smith
- Michael Flippo - Shady
- Gavin McCulley - General Holden's Aide
- Bob Harter - Dr. West
- Henry Bazemore Jr. - Senior MP
- William Covington - Soldier (uncredited)
- Joey Naber - (uncredited)
- Felix Solis - William Hele
- Marnie Schulenburg - Megan Meyer
- Happy Anderson - Bear
- Bill Ladd - Cally
- Ashley LeConte Campbell - Hospital Administrator
- William Howard Bowman - Records Clerk
- Dee Johnson
- Mark Gordon
- Katherine Fugate
Catherine Bell interpreta a Denise Sherwood en la serie.
Brian McNamara hace el papel de Michael Holden.
Wendy Davis hace el papel de Joan Burton.
Terry Serpico interpreta a Frank Sherwood en la serie.
Kelli Williams hace el papel de Jackie Clarke.
Alyssa Diaz hace el papel de Gloria.
J. J. Soria hace el papel de Hector Cruz.
Torrey DeVitto interpreta a Maggie Hall en la serie.
Ashanti interpreta a Latasha Montclair en la serie.
Elle McLemore hace el papel de Holly Truman.
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