- Amanda Bynes - Crystal Dupree
- Brent Barry - Brent Barry
- Elizabeth Manley - Elizabeth Manley
- Jsu Garcia - Robo
- Carl Lewis - Carl Lewis
- Shaquille O'Neal - Shaquille O'Neal
- Bob Costas - Bob Costas
- Brandon Tartikoff - Brandon Tartikoff
- Chris Myers - Himself
- Gary Carter - Self
- Barbara Keegan - Product Rep
- Mailon Rivera - Latrelle Shabazz
- Patricia Manterola - Carman Caballo
- Kathleen McClellan - Susie
- Jerry Jones - Jerry Jones
- Dyan Cannon - Dyan Cannon
- Tracy McGrady - Tracy McGrady
- Hannah Storm - Hannah Storm
- Rosalind Chao - Karen
- Gerry Del Sol - Stage Manager
- William Frankfather - Client Rep
- Judy Gold - Client Rep
- Ann Meyers - Ann Meyers
- Kim Tavares - Rita
- Michael Fairman - Buddy Reingold
- Fran Bennett - Amelia Halimon
- George Wallace - Deacon Delbert Henry
- Chris Ellis - Henneman
- Al Rodrigo - Obless Obliche
- Brian Robbins
Robert Wuhl hace el papel de Arliss Michaels.
Sandra Oh interpreta a Rita Wu en la serie.
Jim Turner interpreta a Kirby Carlisle en la serie.
Michael Boatman interpreta a Stanley Babson en la serie.
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