- Teresa Ganzel - Greedy Gretchen
- Phil Leeds - Lyle Wormold
- Roger C. Carmel - Merl Denker
- Anne Schedeen - Lisa Page
- Peter Palmer - Jeff
- Gloria LeRoy - Nancy
- Dick O'Neill - Walter Nessle
- Rebecca Holden - Bunny / Twinkie
- Michael Bell - Michael
- Edward Andrews - Grandpa Tripper
- Simone Griffeth - Nancy Norwood
- Hope Clarke - Second Nurse
- Bob Hastings - John Callan
- Joey Forman - Policeman
- Hugh Gillin - Mr. Alden
- James Cromwell - Detective Lannigan
- Sally Kirkland - Sally
- Paula Shaw - Ruth Wood
- John Getz - Lee Tripper
- Ellen Travolta - Mrs. Marconi
- Cynthia Harris - Mrs. Layton
- Dick Sargent - Lloyd Cross
- Jordan Clarke - Bill
- Priscilla Morrill - Mrs. Snow
- Robert Mandan - James Bradford
- Barry Gordon - Gilbert Larwin
- Frank Aletter - Tom Latham
- Ed Gilbert - Lt. Briscoe
- Sue Ane Langdon - Cindy's Aunt Becky
- Nancy Andrews - Secretary
- Stanley Kamel - Clean Cut Man
- Peter Mark Richman - Reverend Snow
- Karen Austin - Denise
- Karen Austin - Jennifer
- Joel Brooks - Dr. Prescott
- Joanna Kerns - Bobby Trilling
- Ruta Lee - Marsha Whitewood
- Donald Petrie - Officer Jim Bolton
- Jeanne Bates - Alice
- Albert Carrier - Maurice
- Jan Sterling - Judge Sheffield
- Elaine Giftos - Randy Buckley
- Elaine Giftos - Darlene
- John Fiedler - Morris Morris
- James Staley - Special Agent Banning
- Terry Kiser - Max
- Terry Kiser - Mr. Canon
- Hamilton Camp - Bart Furley
- John Brandon - Police Captain James
- Joyce Bulifant - Mrs. Cross
- William Pierson - Dean Travers
- Stuart Nisbet - Mr. Crawford
- Mary Cadorette - Vicky Bradford
- Frances Lee McCain - Kelly
- John McCook - Alan
- John McCook - Doug Cooper
- Amzie Strickland - Gladys Moore
- Gino Conforti - Felipe Gomez
- Jordan Charney - Frank Angelino
- Jordan Charney - Mr. Layton
- Jeffrey Tambor - Tom Miller
- Jeffrey Tambor - Phillip Greene
- Jeffrey Tambor - Winston Cromwell III
- J. Pat O'Malley - Leo Moran
- Bill Fiore - Harvey
- Sondra Currie - Shelley Green
- Sondra Currie - Sherry Lee
- Macon McCalman - Roland Wood
- George Dickerson - The Boss
- Pamela Brull - April
- John Larroquette - Cop
- Peter Schuck - Pete
- Barbara Stuart - Mrs. Medford
- Bob Sherman - Katy's Brother
- Keene Curtis - Andrew Gainer
- Keene Curtis - Dr. Todson
- Britt Leach - The Husband
- Britt Leach - Chuck
- Shera Danese - Barmaid
- Karen Berger - Celise
- Ann Wedgeworth - Lana Shields
- Janet Wood - Frances
- Mina Kolb - Mrs. Alden
- Christina Hart - Karen
- Christina Hart - Francesca Angelino
- Jennifer Walker - Samantha Alden
- Sally Kemp - Joanna Latham
- Paul Kent - Dr. Anderson
- Debbie Bartlett - Marlene
- Murray Matheson - Roger
- Shell Kepler - Didi
- Shell Kepler - Luanne
- Brad Blaisdell - Mike the Bartender
- Rod Gist - Big Eddie
- Lois Hamilton - Katy Williams
- Lois Hamilton - Rita
- Herman Poppe - Wally
- Jay Garner - Jason Defarge
- Louise Williams - Laura
- Louise Williams - Chloe Brown
- Marty Brill - Mike O'Connell
- Frank O'Brien - Director
- Mickey Deems - Gambel
- Barrie Youngfellow - Debbie
- Terence Goodman - Roger
- Robert Machray - Doug
- Alan McRae - Phil
- Daniel Trent - Elliott
- Rudolph Willrich - Special Agent Roth
- Damian London - Captain
- Harold J. Stone - Bernie Bustamente
- Mickey Morton - Floyd
- Reb Brown - Elmo Hacker
- Patricia Barry - Mrs. Claremont
- Ric Carrott - Rick
- Steve Sandor - Harvey
- Tori Lysdahl - Shirley
- Heather Lowe - Brenda
- Shane Sinutko - Billy Todson
- Joe George - Chauffeur
- Ruth Manning - Nurse Engel
- Ruth Manning - Harriet Hadley
- Indy Shriner - Barbara
- Steve Vinovich - Ben Baxter
- Lynda Beatie - Sheila
- Marie Laurin - Denise
- David Tress - Virgil
- Pamela McMyler - Ms. Callahan
- Steven Anderson - Higgins
- Kate Murtagh - Gertrude
- Laurette Spang - Inga
- Fay DeWitt - Woman in Flower Shop
- Vernon Weddle - Mr. Weddle
- Alan Manson - Mike the Cop
- Alan Manson - Mr. Snow
- Jennifer Gay - Bonnie Chamberlain
- Michael Lombard - Lucien
- Rod Colbin - Mr. Hadley
- Jillian Kesner - The Sister
- Hank Garrett - The Bookie
- Janice Kent - Cheryl Gainer
- Sarah Marshall - Madame Clara
- Dorian Lopinto - Betty Jean Travers
- Robin Eisenman - Veronica Furley
- Robert Riesel - Motel Clerk
- Bobby Ellerbee - Dr. Cooper
- Cisse Cameron - Melody Wilson
- Kit McDonough - Patricia Crawford
- Melanie Vincz - Sylvia
- Ted Chapman - Meek Man
- Kopi Sotiropulos - Larry's Uncle
- Karen Fredrik - Barmaid
- Jenifer Shaw - Veronica
- Sandra de Bruin - Chloe
- J.J. Barry - Compton
- Margaret Wheeler - Woman Customer
- Gary Cookson - Alex
- Brian Byers - Tom Ferguson
- Alan Koss - Ralph
- Suzanne Hunt - Party Girl (uncredited)
- Will MacMillan - Policeman (as W.G. McMillan)
- Tom Lacy - Mr. Wagstaff
- Jess Nadelman - Michael Winthrop
- Alba Francesca - Joan
- Ivana Moore - Sandy
- Seth Foster - Steve the Bartender
- Nora Gaye - Waitress
- Judy Kain - Joan Ferguson
- Bernie West
- Michael Ross
Frances Lee McCain interpreta a Kelly en la serie.
Jeffrey Tambor interpreta a Winston Cromwell III en la serie.
Phil Leeds hace el papel de Lyle Wormold.
James Cromwell hace el papel de Detective Lannigan.
John Ritter interpreta a Jack Tripper en la serie.
Joyce DeWitt hace el papel de Janet Wood.
Priscilla Barnes interpreta a Terri Alden en la serie.
Don Knotts interpreta a Ralph Furley en la serie.
Richard Kline interpreta a Larry Dallas en la serie.
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