- Penn Jillette - Self
- Oscar Goodman - Self
- Daniel Boulud - Self
- Anabel Hernández - Self
- Dave McMillan - Self - Chef / Owner, Joe Beef
- Zach Zamboni - Self
- Andy Ricker - Self
- Martin Picard - Self - Chef
- David Choe - Self - Artist
- Roy Choi - Self - Chef
- Roy Kim - Self - Restaurant Owner
- Eric Ripert - Self
- Eric Ripert - Self - Chef, Le Bernardin
- Mario Galeano - Self - Ondatrópica Member
- Will Holland - Self - Ondatrópica Member
- Patrick Lagacé - Self - Journalist
- Cherie Nutting - Self - Photographer
- Christopher Gibbs - Self - Antique Dealer
- Bill Murray - Self
- Iggy Pop - Self
- Barack Obama - Self
- Alison Mosshart - Self
- Margo Price - Self
- Abel Ferrara - Self
- Asia Argento - Self
- Danny Trejo - Self
- Al Madrigal - Self
- Mister Cartoon - Self
- Gilbert Melendez - Self
- Nick Diaz - Self
- Nate Diaz - Self
- Juan María Arzak - Self - Basque Chef
- Elena Arzak - Self - Basque Chef
- Jesse Boyce - Self
- Joey Yusuf Rasdien - Self - Actor
- Paul Bocuse - Self
- ???? - Self
- Ko Iwagami - Self
- Ty Mitchell - Self
Bill Murray interpreta a Self en la serie.
Anthony Bourdain hace el papel de Self - Host.
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