- Lucy Liu - Ling Woo
- James Marsden - Glenn Foy
- Josh Hopkins - Raymond Millbury
- Vonda Shepard - Vonda Shepard
- Peter MacNicol - John Cage
- Robert Downey Jr. - Larry Paul
- James Le Gros - Mark Albert
- Jill Clayburgh - Jeannie McBeal
- Tracy Middendorf - Risa Helms
- Donna Hanover - Receptionist
- Paul Reubens - Louis
- Stuart Pankin - Mr. Handy
- Melanie Chartoff - Joanne Poole
- Jim Davidson - Process Server
- Farrah Fawcett - Robin Jones
- Jessica Harper - Sister Helen
- Gloria Gaynor - Gloria Gaynor
- James Naughton - George McBeal
- Eric Christmas - Judge Maynard Snipp
- Mark Metcalf - Attorney Walden
- Richard Kiley - Seymore Little
- Barry Humphries - Claire Otoms
- Taye Diggs - Jackson Duper
- Heidi Mark - Alice Gaylor
- Aaron Lustig - Attorney Bowe
- Rob Schneider - Ross Fitzsimmons
- Nancy O'Dell - Reporter #2
- Anne Haney - Anne Haney
- Josh Groban - Malcolm Wyatt
- Jacqueline Bisset - Frances Shaw
- Matthew Perry - Todd Merrick
- Kathryn Joosten - Sister Alice
- Jerry Lambert - Reporter #3 / Anchor
- Susan Krebs - Judge Lee Kensington
- Orson Bean - Marty Brigg
- Alexandra Holden - Jane Wilco
- John Fleck - Attorney Spicer
- John Ritter - George Madison
- Shea Farrell - Priest (uncredited)
- Jason Gedrick - Joel
- Betty White - Dr. Shirley Flott
- Ted Marcoux - Louis Walters
- Elton John - Elton John
- Wayne Newton - Harold Wicks
- Natasha Gregson Wagner - Hannah Puck
- Roy Brocksmith - Judge Raymond Norway
- Mariah Carey - Candy Cushnip
- Christopher Neiman - Bob
- Lydia Look - Leigh Woo
- Kellie Waymire - Chrissa
- Richmond Shepard - Joel's Father
- Phil Leeds - Judge Dennis 'Happy' Boyle
- Dan Butler - Attorney Bender
- Christina Ricci - Liza Bump
- Tim Thomerson - Mr. Daley
- Albert Hall - Seymore Walsh
- Albert Hall - Judge Seymore Walsh
- Curtis Armstrong - Tiny Tim Fallow
- Kurt Fuller - Bernard Marsh
- Holmes Osborne - Principal Figgins
- Aloma Wright - Judge Aloma Harris
- Harvey J. Alperin - Foreman
- David Ogden Stiers - Judge Andrew Peters
- Arturo Gil - Elf
- Ryan Hansen - Student MC
- Louis Giambalvo - Harold Jordan
- Clare Carey - Mary Clapp
- Bobby Cannavale - Wilson Jade
- Kristin Dattilo - Laura Payne
- Lara Flynn Boyle - Helen Gamble (uncredited)
- Nancy Stephens - Judge Washington
- Carl Reiner - Johnson Buck
- James Sutorius - Daley's Attorney
- Bil Dwyer - Bandleader
- Gibby Brand - Judge William McGough
- Jordan Baker - Marissa Jackson
- Peter Choi - The Foreman
- Amy Warner - Dr. Wazard
- Richard Lee Jackson - Jason Tresham
- Caitlin Dulany - Laura Jewell
- Justin Theroux - Raymond Brown
- Kayren Butler - Jody Silverman
- Tony Plana - Judge Warren Figueroa
- Claudette Nevins - Ms. Hollings
- Christine Ebersole - Marie Stokes
- Shawn Michael Howard - Ben
- Eric Scott Woods - Jack Clooney
- Bob Glouberman - Wally Pike
- Bonnie-Jill Laflin - Robert Palmer Girl (uncredited)
- Brad Grunberg - Emcee
- Murray Rubin - Seymore
- Michael Reilly Burke - Mr. Wells
- Neil Giuntoli - Ralph Witton
- John de Lancie - Jackson Poile
- Mark Linn-Baker - Sheldon Maxwell
- Eileen Ryan - Bria Tolson
- James Greene - Father Robert McNamara
- Joel Polis - Attorney Woodson
- Lee Wilkof - District Attorney Nixon
- Richard T. Jones - Matt Griffin
- Sam Anderson - Mark Harrison
- Lisa Thornhill - Kimberly Goodman
- Caroline Aaron - Laura Dipson
- Vyto Ruginis - Mr. Goodman
- Francesca P. Roberts - Judge Cynthia Harris
- Christopher John Fields - Mr. Goodman's Attorney
- Joel Brooks - Dr. Hubbell
- Bruce Willis - Dr. Nickle (uncredited)
- Mary Mara - Julie Stall
- Randy Oglesby - Harvey Kent
- Talia Balsam - Shelia Kent
- Gary Graham - Rodney Wilcox
- Tia Riebling - Melissa Walker / Waitress
- H. Richard Greene - Judge Paul Stewart
- Fred Willard - Dr. Harold Madison
- Fred Sanders - Dr. Burns
- Keith MacKechnie - Arthur Gale
- Haley Joel Osment - Eric Stall
- Patrick Pankhurst - Dr. Stewart
- Elliot Goldwag - Foreman
- Conor O'Farrell - Attorney Jordan
- Peter Birkenhead - Steve
- Kenneth Kimmins - Mr. Forsley
- Larry Brandenburg - Judge Raynsford Hopkins
- Bruce Nozick - Attorney
- Paul Perri - Attorney Serrano
- Lauren Bowles - Callie Horne
- Anne Heche - Melanie West
- Anna Nicole Smith - Myra Jacobs
- Zach Grenier - Attorney Benson
- Tracey Ullman - Dr. Tracey Clark
- J. Karen Thomas - Karen Martin-Gray
- Peter White - Senator Harold Watkins
- Linda Gehringer - Shirley Peterson
- Jennifer Holliday - Lisa Knowles
- Harrison Page - Reverend Mark Newman
- Ruth Westheimer - Ruth Westheimer (voice)
- Shirley Scott - Congregant
- George Anthony Bell - Congregant
- Orlando Ashley - Congregant
- Norma Michaels - Elderly Lady
- Ed Brigadier - Foreman
- Eugene Greytak - Pope
- Amentha Dymally - Woman
- Robert Costanzo - George Chisholm
- Amy Castle - Young Ally
- Amy Castle - Ally Age 8
- Anson Mount - Kevin Wah
- Carmen Argenziano - Harry Wah
- Maria Pitillo - Paula Hunt
- Wendy Cutler - Shirley
- Jane Clark - Nurse
- Paul Willson - Ross Feinman
- Tony Campisi - Joseph
- Joyce Brothers - Dr. Joyce Brothers
- Jody Wood - Officer Kent
- Brad Blaisdell - Dr. Alfonso Moreno
- Tony Shalhoub - Albert Shepley
- Dyan Cannon - Jennifer 'Whipper' Cone
- Judith Montgomery - Foreperson
- David Dukes - Johnson Biblico
- Kate McNeil - Marianne Harper
- LaTanya Richardson Jackson - Attorney Yvette Rose
- Rosie O'Donnell - Dr. Hooper
- Fred Ponzlov - Foreman
- Debra Christofferson - Vicky Sharpe
- Jennifer Rhodes - Gladys Claven
- Susan Blommaert - Judge Fox
- Ashley Gardner - Martha Claven
- Mary Beth McDonough - Attorney Gloria Stepp
- Noelle Evans - Miss Tyler
- Michael Gross - Mr. Volpe
- Peter Tomarken - Reporter
- Antonio Sabàto, Jr. - Kevin Wyatt
- Sara Botsford - Attorney Post
- Denis Arndt - Michael Mannix
- Christine Estabrook - Bonnie Mannix
- Jesse L. Martin - Dr. Greg Butters
- Enya Flack - Kimba
- James Kiriyama-Lem - Foreman
- Barbara Alyn Woods - Kelly Philbrick
- Anne-Marie Johnson - District Attorney Foster
- Paul Bartel - Doctor
- Robert Picardo - Barry Philbrick
- Judith Drake - Foreperson
- Darin Cooper - Pedestrian
- Jill Noel - Girlfriend #1
- Paige Tamada - Girlfriend #2
- Sarah Hagan - Girlfriend #3
- Mark Mueller - Foreman
- Michael Badalucco - Jimmy Berluti (uncredited)
- Yves Bright - Handsome Man (uncredited)
- Ray Walston - Minister Breyer
- Lillian Byrd - Mrs. Helms
- Alec Murdock - Mr. Helms
- Irene White - Heckler #2
- Laura Henry - Heckler #3
- Dee Wallace - Gail Clarkson
- Paula Newsome - Phyllis Butters
- Michael Kagan - Robert Perry
- Victoria Garcia-Kelleher - Helen Fischer
- Tom Kemp - Foreman
- Eric Cohen - Twin
- Eric Cohen - Dancing Twin
- Nicki Aycox - Kim Puckett
- Gladys Knight - Gladys Knight
- Al Green - Al Green
- Marnie Mosiman - Marcia Gallin
- Tim Snay - Waler Gallin
- Wylie Small - Mrs. Puckett
- Brian Evers - Mr. Puckett
- Ashlee Turner - Julie
- Andy Umberger - Mr. Fordham
- Drew Snyder - Hughes
- Sy Smith - Singer
- Sy Smith - Backup Singer
- Jack Shearer - Judge Alan Rancor
- Renée Elise Goldsberry - Singer
- Renée Elise Goldsberry - Backup Singer
- John Harnagel - Foreman
- Jim O'Heir - Steve Mallory
- Lenny Wolpe - James Russell
- John Short - Larry
- Vicki Lawrence - Dana
- Ron Taylor - Singer in Bar
- Valeri Ross - Security Officer
- Christopher Michael - Police Officer
- Tonya Reneé Banks - Elf
- Joe Gieb - Elf
- Cindy Sorenson - Elf
- Kevin Thompson - Elf
- Jon Simanton - Elf
- Robert Curtis Brown - Attorney McCabe
- Gina Philips - Sandy Hingle
- Gerry Becker - Attorney Myron Stone
- Wendy Worthington - Margaret Camaro
- Linda Pine - Lynn Hart
- Brad Wilson - Harold
- Joanna Sanchez - Janine Waller
- Mark Brown - Herbert Beacon
- Barry White - Barry White
- William Stanford Davis - Jim
- Steve Cohen - Dancing Twin
- Steven Clawson - Courtroom Singer (uncredited)
- Austin Tichenor - D.A. Tisbury
- Frederick Koehler - Marcus
- Alex Hyde-White - Louis' Co-worker
- Ricki Dale - Leslie
- Aaron Knight - Clerk
- Julius Tennon - Officer #1
- Kristen Kerr - Robert Palmer Girl (uncredited)
- Carlos Jacott - Bob
- Shane Dawson - Young Fish
- Paul Dooley - Nicholas Engblume
- David E. Kelley
- Jonathan Pontell
- Mike Listo
- Bill D'Elia
- Steve Robin
- Jeffrey Kramer
- Danny Lux
Barry Humphries hace el papel de Claire Otoms.
Holmes Osborne interpreta a Principal Figgins en la serie.
Bruce Willis interpreta a Dr. Nickle (uncredited) en la serie.
Carl Reiner interpreta a Johnson Buck en la serie.
Phil Leeds interpreta a Judge Dennis 'Happy' Boyle en la serie.
Caroline Aaron interpreta a Laura Dipson en la serie.
Susan Blommaert hace el papel de Judge Fox.
Lucy Liu interpreta a Ling Woo en la serie.
Robert Downey Jr. hace el papel de Larry Paul.
Tony Shalhoub hace el papel de Albert Shepley.
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