- Mark Priestley - Dan Goldman
- Mirrah Foulkes - Jo Mathieson
- Jack Campbell - Steve Taylor
- Andrew Supanz - Bartholomew West
- Jolene Anderson - Erica Templeton
- Erik Thomson - Mitch Stevens
- Conrad Coleby - Scott Zinenko
- Natalie Saleeba - Jessica Singelton
- Wil Traval - Jack Quade
- Brian Vriends - Ben Markham
- Tammy Macintosh - Charlotte Beaumont
- Christopher Gabardi - Vincent Hughes
- John Howard - Frank Campion
- Allison Cratchley - Zoe Gallagher
- Chris Vance - Sean Everleigh
- Virginia Gay - Gabrielle Jaegar
- John Waters - Mike Vlasek
- Kip Gamblin - Adam Rossi
- Ella Scott Lynch - Claire Anderson
- Alix Bidstrup - Amy Fielding
- Alexandra Davies - Cate McMasters
- Alexandra Davies - Naomi Collins
- Paul Tassone - Nelson Curtis
- Paul Tassone - Jake Bosac
- Paul Tassone - Colin Bell
- Maggie Dence - Lyn Brown
- Michael C. Gwynne - Adam Gregson
- Helen Dallimore - Amanda Sales
- Kate Fitzpatrick - Natasha Reece
- June Salter - Sister Marguerite
- Bridie Carter - Karen McCarthur
- Charles Tingwell - Dr Harry McKay
- Adam Saunders - Josh Koumanis
- Stuart Wagstaff - Reg Howard
- Deborah Galanos - Sarah Madsen
- Michela Noonan - Julie Allen
- Andrew Tighe - Chris Madsen
- Greg Ellis - SRA Worker #3
- Matthew Krok - Aiden McGregor
- Natasha Beaumont - Rebecca Green
- Robin McLeavy - Katherine Burnett
- Christian Manon - Smythe
- Keiynan Lonsdale - Corey
- Kristian Schmid - Thomas Ferry
- Kellie Jones - Amy Jacobs
- Kellie Jones - Young Laura
- Chris Patton - Gang Member
- Amanda Bishop - Ms. Alexander
- Amanda Bishop - Theresa Pye
- Sophie Bloom - Isabelle
- Zoe Houghton - Carol Blake
- Zoe Houghton - Chloe Friar
- John McNeill - Allan Miller
- Mark Simpson - Matthew Holgrem
- Bill Conn - Vic McArdle
- Megan O'Connell - Alisa
- Lyn Collingwood - Laraine Parkes
- Scott Major - Jason Richard
- Daniel Amalm - Moe Atsidakos
- Jon Pollard - Troy Smart
- Jon Pollard - Nigel 'Zap'
- Ian Meadows - Jeff Weiss
- Rebekah Elmaloglou - Justine Addison
- Andy Anderson - Lewis Dowd
- Andy Anderson - Alan Mitchell
- Callan Mulvey - Stewie Holder
- Angelo D'Angelo - Damien Carr
- Steve Jacobs - Dr Harry Williams
- Steve Jacobs - Dr. Harry Williams
- Gennie Nevinson - Mrs Levine
- Dinah Shearing - Judith Aston
- Terry Binding - Sister Jane Foster
- Michael Caton - Bob Parkin
- Chin Yu - Mrs Cheng
- Michael Denkha - Mario Constantine
- Laurence Breuls - Scott Chambers
- Kim Hillas - Joan Marden
- Todd Dwyer - Police Officer
- Anthony Jensen - Dealer
- Elizabeth Maywald - Sophie Williams
- David Baldwin - Adam Beauman
- Emma Blake - Kylie Green
- Belinda Cotterill - Angie Meadows
- Belinda Cotterill - Angela Roberts
- Belinda Cotterill - Angela Meadows
- Mariette Rups Donnelly - Mrs Walker
- Tony Forrow - Matt
- Alex Hughes - Tim Williams
- Steve Judkins - Arnie Walker
- Alfie Lee - Policeman
- Zika Nester - Gilda Clemenko
- Sandy Winton - Greg Newman
- Beth Champion - Melissa
- Geoff Cartwright - Dr Rob Bowen
- Geoff Cartwright - Rob Bowen
- Sarah Snook - Sophie
- Jackson Raine - Dr James Wu
- Jackson Raine - Dr Wu
- Sophie Wright - Choir Girl
- David James - Karl Von Hunter
- David James - Richard Davies
- Tamsin Carroll - Nikki Collins
- Tamsin Carroll - Tanya Foster Wallace
- Judy Ferris - Maggie Quinnell
- Linda Newton - Jenny Morrison
- Maya Stange - Emily Watson
- Christine Stephen-Daly - Rachel McMahon
- Annie Byron - Julie Costello
- Brian Rooney - Robbie Watson
- Steve Rodgers - Dean Johnston
- Syd Conabere - Maurie Taylor
- Tahir Bilgic - Mr Mustafa
- Elizabeth Fleming - Phoebe Gibbs
- Rob Steele - Jimmy Dwyer
- Paula Arundell - Nura Arkuna
- Georgia Adamson - Josie
- Francine Bell - Kebo Arkuna
- Maurice Morgan - Abouhd
- Daniel Roberts - David McLachlan
- Peter Collingwood - Lionel Macken
- Mary Acres - Deidre Macken
- Robert Hughes - Alan Fitzer
- Nicky Ruscoe - Equip Team Leader
- Kerry Walker - Barbara Phillips
- Lauren Hewett - Tracey Hrnjack
- Denise Roberts - Janice McGregor
- Bevan Wilson - Malcolm Featherstone
- Christopher Dibb - Tony Pinkton
- Martin Dingle Wall - Greg Howard
- Martin Dingle Wall - Mick
- Lyn Lovett - Celia White
- John Walker - Tom Moore
- Kym Wilson - Raelene Gregson
- Peter Gwynne - Russell Geddes
- Craig Ashley - Ralph Reynolds
- Mark Fairall - Water Taxi Captain
- Rene Naufahu - Gary Headley
- John Brumpton - Steve Casey
- Justine Clarke - Samantha O'Hara
- Justine Clarke - Dr Samantha O'Hara
- Justine Clarke - Dr. Samantha O'Hara
- Roy Billing - Barry Croft
- Tony Girdler - Vince Michaels
- Terence Crawford - Paul Roebuck
- Pauline Terry-Beitz - Ma O'Connell
- Garry Scale - Russ
- Michael McGlinchey - Darren O'Connell
- Brian Meegan - Alex Heard
- Alan Cinis - Karl Updike
- Alan Cinis - Dr Karl Updike
- David Wheeler - Mr Meadows
- Marilyn Mayo - Mrs Mendohlson
- Damian de Montemas - Mike McGrath
- Anthony Brandon Wong - Carlo de Sousa
- Geoff Milton - Jack Carnegie
- Jean Bain - Mrs Taylor
- Tamblyn Lord - Craig Allen
- Christine Greenough - Betty
- Sarah Chadwick - Francesca Norman
- Wayne Blair - Kenny Baxter
- Ben Gabriel - Mr Kucharski
- Nicholas Ryan - Eric Turner
- Simone Buchanan - Mitchie Bell
- Matt Doran - Troy Lyneham
- Adam Hedditch - Allan
- Chris King - Mr Mellett
- Linda Hartley - Linda Taylor
- Paul Kelman - Kevin Taylor
- Rod Mullinar - Prof. Richard Craig
- Rod Mullinar - Richard Craig
- Vic Rooney - Trevor Jamieson
- Samantha Noble - Kylie Monroe
- Scott Lowe - Mark Monroe
- Anthony Hayes - Krys Goretski
- Max Phipps - Joe Goretski
- Julie Godfrey - Colleen Delaney
- Kathleen Warren - Mrs Kouros
- Marcus Eyre - Laurie Styles
- Albin Pahernik - Mr Anderson
- David Taylor - Priest
- Natalie Bassingthwaighte - Young Deidre
- Virginia Hey - Joanna Travers
- Anthony Martin - Stan Jacobsen
- Donal Forde - Patrick McCawley
- Tim Dwyer - Dr Sean Archer
- Richard Mills - Cameraperson
- Rodney Bell - Warwick Geddes
- Russell Newman - Bert Petrakis
- Nick Hardcastle - Jack Petrakis
- Tai Scrivener - Constable Wells
- Tai Scrivener - Policeman
- James Howarth - Strobe
- Anthony Phelan - Gareth McLoughlin
- Damon Herriman - Danny Bucknell
- James Benedict - Adam Bennett
- Neil Fitzpatrick - Prof. Brennan
- Mark Lee - Chen Wai
- Scott Gary - Guard
- Bill Young - Don McClusky
- Bill Young - Owen Doyle
- Josh Quong Tart - Vincent Sterling
- Josh Quong Tart - Matt Horner
- Susan Kennedy - Theatre Sister
- Jeff Truman - Ron Monroe
- Denise Kirby - Pat Matthews
- Frankie Davidson - Stan Humphries
- Alison Van Reelen - Jan Page
- Nick Meenahan - Wayne Fischer
- Skye Wansey - Sandy Morris
- Vanessa Downing - Helen Lancaster
- Alan Zitner - Ian Lang
- Stephen Yates - Al Crawford
- Betty Bobbitt - Olivia Macreadie
- Waddah Sari - Abdul Khouri
- Fiona Mahl - Zoe Wilks
- Andrew Wholley - Cameron Calder
- Brett Climo - Bryan Taylor
- Martin Vaughan - Ryan Sullivan
- Martin Vaughan - Arthur
- Martin Vaughan - Arthur Frew
- Barbara Wyndon - Iris Harrison
- Trent Atkinson - Brett Cameron
- Scott Swalwell - Alan Cameron
- Kevin Healy - Mr Cummins
- Kevin Healy - Mr Grattan
- Marie Armstrong - Lou
- Silvio Ofria - Luis Gonzalez
- Silvio Ofria - Roscoe
- Margaret Christensen - Carol Birch
- Margaret Christensen - Edna
- John Walton - Gary Mortimer
- Anna Hruby - Bridget Mortimer
- Polly Cheshire - Kara Mortimer
- Steve Vella - Michael Janovich
- Shirley Cameron - Penny Chalinor
- Joy Hruby - Robin Wallace
- Raj Ryan - Dr Sam Mukherjee
- Raj Ryan - Dr Mukherjee
- Jonathan Hardy - Cliff Unwin
- John Noble - Mr Madsen
- John Noble - John Madsen
- John Noble - Dr Madsen
- Brittany Byrnes - Jacinta Clarke
- Alinta Carroll - Fiona Clarke
- Jonno Zissler - Keenan
- Jonno Zissler - Joel Gomez
- Bill Hunter - Ron Williams
- Ross Newton - Dean Bledsoe
- Jon-Claire Lee - Charlie Hoang
- Bill Bentley - Mark Tanner
- Raymond Donald - Geoff Mason
- Raymond Donald - Stavros
- Andrew McFarlane - David Miller
- Rona Coleman - Cheryl Williams
- Peter Healy - Det. Mitchell
- Brenda De Lacy - Anaesthetist
- Stephen Leeder - Mr Jamieson
- John Clayton - Tony Wilson
- Wadih Dona - Ahmed Aziz
- Julie Herbert - Alison Reynolds
- Julie Herbert - Beatrice Simpson
- Katrina Hobbs - Lily Vale
- Graeme Rhodes - Harley Austin
- Shirley Sheppard - Irene Atherton
- Leo Taylor - Barry Stoneham
- Benjamin McNair - Greg Morris
- Richard Lambeth - Mr Kennedy
- Jenny Wilson - Ruth Kennedy
- Frank Whitten - Ken Burns
- Cecily Polson - June Burns
- Lynette Curran - Hilary Doyle
- Lynette Curran - Anita Petrakis
- Ken Goodlet - Viv Brash
- Henri Szeps - George Bresnic
- Jeanette Cronin - Gail Roberts
- Jill McKay - Mrs Bailey
- Jill McKay - Kitty Conway
- Douglas Hedge - Kevin Simms
- Douglas Hedge - Kevin
- Simmone Jade Mackinnon - Krystal Woods
- Helen Higgins - Susan Slattery
- Diane Carroll - Mrs Darcy
- Tim Page - Clive Grimshaw
- Joanne Cahill - Ellen Collins
- Daniel Kellie - Aden Calder
- Daniel Kellie - Ashley Ciantar
- Greg Blandy - Vincent
- Scott Hall-Watson - Nurse
- Mark Hennessy - Brian Daley
- Mark Hennessy - Rescue Leader
- Damian Rice - Lindsay Farlow
- Betty Lucas - Sister Bernard
- Robyn Loau - Lin Donald
- Robin Kora - Koro McClutchie
- Diane Craig - Colleen Collins
- Marton Csokas - Brother Thomas
- Mitchell McMahon - Adam Stone
- Paul Chubb - William Lucas
- Les Foxcroft - Bill Lucas
- Judi Farr - Kathleen O'Hara
- Christopher Morsley - Les Karver
- Wayne Pygram - Joel Wallace
- Nicholas Papademetriou - Marco Vuga
- Billy Mitchell - Brad Everly
- Brendan Donoghue - Garry Richards
- Marika Mann - Bubba Levine
- Kath Gordon - Astrid Langley
- Sean Daly - Nick Richards
- Peter Mack - Michael
- Tiriel Mora - Steve Cole
- Alan David Lee - John Jeffries
- Gillian Hyde - Anne Jeffries
- Tempany Deckert - Andrea Carter
- Tony Barry - Frank O'Hara
- Mitchell Butel - Christopher Jones
- Edwina Bishop - Hayley Foster
- Kim Knuckey - Derek Daniels
- Michele Fawdon - Paula Marchetti
- Michele Fawdon - Denise Baumann
- Garry McDonald - Dave Armstrong
- Myles Pollard - Robert Ford
- Julie Hamilton - Mrs Armstrong
- Maggie Blinco - Berry Juniper
- Ken Snodgrass - Charles McKew
- Shane Emmett - Aiden O'Hara
- Barbara Gouskos - Mrs Habib
- Penne Hackforth-Jones - Elise Fletcher
- Celia Ireland - Regina Butcher
- Mick Innes - Rowan Barker
- Peter Callan - Graham Birch
- Marcus Schultz - Foreman
- Jeamin Lee - Interpreter
- Melissa Sosa - Karen
- Rebecca Riggs - Brenda Stewart
- Peter Lamb - Neil Phillips
- Harry Bragg - Mr Nicholls
- Pat Bishop - Hazel Masterton
- Peter Carmody - Ralph Manning
- Ana Maria Belo - Joanne Mitchell
- Josh Picker - Paul Mitchell
- Grant Thompson - Matt Halliday
- Terry Serio - Greg Costello
- Jamie Oxenbould - Phil Oram
- Mary Regan - Trish Rawlins
- Marshall Napier - Mick Mason
- Kim Lewis - Megan Costello
- Luke Carroll - Seb
- Brendan Higgins - Dr Jerry Stafford
- Brendan Higgins - Dr Stafford
- Helen Chebatte - Driver
- Cass Cumerford - Shane Hayes
- Cass Cumerford - Skinny Santa
- Robert Alexander - Daniel Parker
- Amanda Crompton - Kerri Williams
- Jan Ringrose - Alice Garvin
- Faye Montgomery - Betty Adams
- Monroe Reimers - Ashok Patel
- Jake Blundell - Tony Hurst
- Kim De Lury - Mick Todd
- Kim De Lury - Andrew Parer
- Peter Whitford - Russell Woods
- Alexandra Fowler - Juliette McAllistair
- Alexandra Fowler - Juliette McAlistair
- Lara Cox - Cathy Maxwell
- Melissa Jaffer - Eileen Sullivan
- Marta Kiec-Gubala - Alison Butler
- Amos Szeps - Jeff Huxley
- Rhondda Findleton - Sharon Ellison
- Antonia Murphy - Donna Julius
- Ling Cooper Tang - Dr Kylie Preece
- Ling Cooper Tang - Kylie Preece
- Ling Cooper Tang - Barbara Chan
- Chris Galletti - Graham Julius
- Fred Chen - Theatre Orderly
- John McTernan - Geoff Cavendish
- Pippa Grandison - Simone Carlisle
- Andrea Moor - Alana Devlin
- Troy Planet - Colin Delaney
- Lois Ramsey - Thelma Franklin
- Connie Hobbs - Ruby Nolan
- Duncan Wass - Ewen Farris
- Shaun Loseby - Young Prankster
- Robin Queree - Ian Albert
- Grant Bowler - Darren Rigg
- Morgan O'Neill - Roger Fleming
- Ashley Fairfield - Roger Double
- Alyssa McClelland - Zoe Dell
- Richard Carter - Alistair Walsh
- Paul Pantano - Nicholas Walsh
- Peter Sumner - Errol Baumann
- Rebecca Hobbs - Rachel Hobbs
- Simon Elrahi - Mehmet Shammiraz
- Tony Helou - Mr Saad
- Simon Chilvers - Brian Toomey
- Tim McCunn - Peter Maroney
- Andrew Hunter - Construction Foreman
- Tina Bursill - Margaret Evans
- Aaron Blabey - Scott Lacey
- Emily Perry - Deb
- John Haas - Police Officer
- John Haas - Policeman no.1
- Liz Burch - Di Richards
- Robyn Gibbes - Gabrielle Flanagan
- Kay Eklund - Maisie Simms
- Stuart Tilse - Chaplain
- Daniel Krige - Paul Millard
- Deborah Clay - Lisa Millard
- David Bugeja - Tim Watson
- Joy Smithers - Rose Carleton
- Jean Taylor - Enid Jones
- Rebecca Smart - Charlie Wilde
- Peter Kowitz - Jimmy Frankston
- Derek Amer - Bryce Jones
- Shant Sarkissian - Sparring Partner
- Carole Skinner - Sandra Gillespie
- Arianthe Galani - Gilda Poletti
- John Meillon Jr. - Sam Pritchard
- Chris Mitchell - Gavin Pritchard
- Eric Bana - Rob Biletsky
- Jason Clarke - Eddie Furlong
- John Adam - Tom Snowdon
- Robyn Moase - Rosemary Armstrong
- Rob Carlton - Col Beaty
- Kieran Darcy-Smith - Gordie Hallam
- David O'Connor - Constable Davis
- Ann Burbrook - Carol Sherwood
- Bojana Novaković - Rachel Carpenter
- Tanya Lawson - Elise Poulos
- John Hamblin - Alan Knight
- Bruce Venables - Bosco the Clown
- Caitlin McDougall - Jodie Reeves
- Treffyn Koreshoff - Rowen Price
- Grant Galea - Bomb Squad Officer
- Greig Fraser - Courier
- Rowena Wallace - Katrina Ford
- Alan Flower - Dave Winton
- Elise Greig - Felicity Sanders
Greg Ellis interpreta a SRA Worker #3 en la serie.
Alexandra Davies interpreta a Cate McMasters en la serie.
Mirrah Foulkes hace el papel de Jo Mathieson.
Jack Campbell interpreta a Steve Taylor en la serie.
Andrew Supanz interpreta a Bartholomew West en la serie.
Jolene Anderson interpreta a Erica Templeton en la serie.
Tammy Macintosh interpreta a Charlotte Beaumont en la serie.
John Howard interpreta a Frank Campion en la serie.
Kip Gamblin interpreta a Adam Rossi en la serie.
Ella Scott Lynch interpreta a Claire Anderson en la serie.
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