- Noelle E Parker - Kathy Lee
- Kathryn Winslow - Irene
- Wendy Schenker - Social Worker
- Jane Krakowski - Beth Barnes Beagle
- Robb Derringer - Chad Beagle
- Ginger Minj - Tommy / Fanny Pack
- Joanna Sanchez - Carmen
- Aidan Fiske - Adam
- Kristen O'Meara - Lila
- Trinity the Tuck - Danielle Dupri
- Jimmy Ray Bennett - Kevin
- Todd Sherry - Ewan
- Ptolemy Slocum - Paulie
- Jujubee - Lee Saint Lee
- Constantine Rousouli - Jordan
- Diane Delano - Police Officer
- Pandora Boxx - Pandora Boxx
- Jimmy Walker Jr. - Farmer
- Chet Grissom - TV Host
- Lockhart Brownlie - Dancer #1
- Troy Hines II - Dancer #5
- Erin Flynn - Angry Protester
- Mary Kay Place - Carolanne
- Michael Cyril Creighton - Christian
- Eddie Shin - Doctor
- John Rubinstein - Doctor
- Stacie Greenwell - Loretta
- Lisa Linke - Alyssa
- Jason Michael Snow - Seth
- Lorraine Bracco - Herself
- Amie MacKenzie - DiDi
- Leann Lei - Nurse
- Jill Remez - Nurse Jasmine
- Christine Corpuz - Nurse Amber
- Greg Lee - Doctor
- Lidia Pearl - Destiny
- Aaron Coleman - Man
- Chris McKernan - Gas Station Guy
- Kevin Daniels - Darrell
- Latrice Royale - Fabergé Legs
- Mo Heart - Miss Terri Tory
- Chaunte Wayans - Cherise
- Shelby Steel - Trina
- Mychal Thompson - Rick
- Baadja-Lyne Odums - Mama
- Steven Michael Eich - Club Regular #1
- Kendra Oyesanya - Dancer #1
- Bridget Everett - Anna
- Natasha Leggero - Kath
- Rebecca Metz - Yolanda
- Adam Bartley - Chris
- Terryn Westbrook - Beth
- Armen Nahapetian - Brick
- Reynaldo Gallegos - Karl
- E.E. Bell - Clem
- Aylam Orian - Bud
- Laura Bell Bundy - Bernadette
- Tim Bagley - Lloyd Johnson
- Gregory A. Thompson - Ralph
- Melissa Fosse-Dunne - Rainbow
- Brett Tucker - Officer Peter Dembrowski
- Chad Michaels - Brian Gerrity
- Angel Laketa Moore - Cherise
- Jen Kober - Female Officer
- Robert Arce - Old Man at Bar
- Jade Jolie - Jade Jolie
- Kennedy Davenport - Kennedy Davenport
- Mariah Balenciaga - Mariah Balenciaga
- Ongina - Ongina
- Adrienne Barbeau - Helen
- Marc Singer - Bob
- Socrates Alafouzos - Igor
- Brandilyn Cheah - Granddaughter
- Jaymes Mansfield - Jaymes Mansfield
- Mario Cantone - Alma Joy
- Lynne Marie Stewart - Florence
- Lyndsi LaRose - Bride-to-Be
- Jinkx Monsoon - Edee
- Katya Zamolodchikova - Magda
- Matthew Wilkas - Officer Patrick Kennedy
- Misty Monroe - Officer Rhonda Whyatt
- Raymond Ma - Mr. Hong
- Cathy Chang - Mrs. Hong
- Tommy Snider - Murphy
- Jo Farkas - Mrs. Sweeney
- Annamarie Kasper - Monica (voice)
- Shawana Carter - Tianna
- Devon Diffenderfer - Mr. Hipster
- Teddy Margas - Tony
- Tony Forsmark - Officer Gaska
- Alexis Mateo - Alexis Mateo
- Bianca Del Rio - Bianca del Rio
- Eureka O'Hara - Eureka O'Hara
- Manila Luzon - Manila Luzon
- Mayhem Miller - Mayhem Miller
- Victoria "Porkchop" Parker - Pork Chop
- Valentina - Valentina
- Vanessa Vanjie Mateo - Vanessa Vanjie
- Drew Powell - Carl
- Joel Murray - Motorcycle Cop
- Brandon Delmer Doyle - Audience Member
- Delia Rawdon - Drag Queen Looper
- Miles Faber - Dancer #3
- Michael Patrick King
- Kristan Berona
- RuPaul
RuPaul hace el papel de Robert Lee / Ruby Red.
Izzy G. interpreta a Amber Jasmine "AJ" Douglas en la serie.
Michael-Leon Wooley interpreta a Louis Bell / Cocoa Butter en la serie.
Josh Segarra interpreta a Hector Ramirez / Damien Sanchez en la serie.
Katerina Tannenbaum interpreta a Brianna Douglas en la serie.
Tia Carrere interpreta a Leilani Kala'i / Lady Danger en la serie.
Capítulo disponible en las siguientes plataformas:
