- Stephen Graham - Shang
- Eddie Marsan - Killoran
- Alec McCowen - Reverend Raleigh
- David Hemmings - Mr. Schermerhorn
- Lawrence Gilliard Jr. - Jimmy Spoils
- Cara Seymour - Hell-Cat Maggie
- Roger Ashton-Griffiths - P.T. Barnum
- Peter-Hugo Daly - One-Armed Priest
- Cian McCormack - Young Amsterdam
- Andrew Gallagher - Young Johnny
- Philip Kirk - O'Connell Guard Leader
- Rab Affleck - Plug Uglies Leader
- Bill Barclay - Shirt Tails Leader
- Nick Bartlett - Chichesters Leader
- Robert Goodman - Forty Thieves Leader
- Tim Pigott-Smith - Calvinist Minister
- Liam Carney - Bill The Butcher's Gang #1
- Gary McCormack - Bill The Butcher's Gang #2
- David McBlain - Bill The Butcher's Gang #3
- Dick Holland - True Blue American Speaker
- Katherine Wallach - Jenny's Girl
- Carmen Hanlon - Jenny's Girl
- Ilaria D'Elia - Jenny's Girl
- Laurie Ventry - Resident Woman
- Ford Kiernan - Black Joke Chief
- Alec McMahon - Resident Man
- Nevan Finegan - Dead Rabbit Gang Member
- Dominique Vandenberg - Dead Rabbit Gang Member
- Stuart Yung Sai-Kit - Chinese at Sparrow's Pagoda
- Basil Chung - Elderly Chinese at Pagoda
- Finbar Furey - Satan's Circus Singer
- Sean Gilder - Rat Pit Game Master
- Richard Graham - Card Player (Harvey)
- Richard Strange - Undertaker
- Douglas Plasse - Medical Student
- R. Bruce Steinheimer - Army Recruiter
- David Bamber - Passenger on Omnibus
- Barbara Bouchet - Mrs. Schermerhorn
- Michael Byrne - Horace Greeley
- Lucy Davenport - Miss Schermerhorn
- Maura O'Connell - Street Singer
- Alex Howden - Assistant Hangman
- James Ramsay - Condemned Man (Arthur)
- Iain McColl - Condemned Man (Seamus)
- Louie Brownsell - Legless Soldier
- Gennaro Condemi - She-He
- Kieran Hurley - Recruiter
- John Sessions - Harry Watkins / Lincoln
- Michael Billingsley - Uncle Tom
- Steven Blake - Mr. Shelby
- Giovanni Lombardo Radice - Mr. Legree
- Alexia Murray - Topsy
- Flaminia Fegarotti - Miss Eliza
- Bronco McLoughlin - Assassin
- Channing C. Holmes - Tap Dancer
- Eliane Chappuis - Chinese Whore
- Roberta Quaresima - Whore #1
- Marta Pilato - Whore #2
- Jian Su - Chinese Acrobat
- Man Cao - Chinese General
- Kathy Shao-Lin Lee - Chinese Dancer
- Alexander Deng - Chinese Boy Singer
- Peter Berling - Knife Act Caller
- Patrick Gordon - Surgeon
- Brendan White - Archbishop
- Brendan Dempsey - Provost Marshal Registrar
- Taddeo Harbutt - Unruly Man
- Nazzareno Natale - Don Whiskerandos
- Colin Hill - Nativist Candidate
- Robert Linge - One-Armed Veteran
- Richard Syms - Drunken Repeater
- Christian Burgess - The Mayor
- Gerry Robert Byrne - Draft Official
- David J. Nicholls - O'Connell Guard Leader
- Tim Faraday - Plug Uglies Leader
- Sean McGinley - Forty Thieves Leader
- John Anthony Murphy - Kerryonians Leader
- Terry O'Neill - Chichesters Leader
- Vincent Pickering - American Guard Leader
- Nick Miles - Atlantic Guard Leader
- Ian Pirie - Slaughter Housers Leader
- John McGlynn - Bowery Boys Leader
- Larry Kaplan - Bloodied Bureaucrat
- Leo Burmester - Telegraph Operator #1 (voice)
- Justin Brennan - Telegraph Operator #2 (voice)
- Brian Mallon - Telegraph Operator #3 (voice)
- Joseph P. Reidy - Police Chief
- Joel Strachan - Telegraph Operator
- Bill Murdoch - Robber on Dock
- Angela Pleasence - Woman Accomplice
- Iain Agnew - General Wool
- Michael Hausman - Gunboat Captain
- Bob Colletti - Soldier in Mist
- Martin Scorsese - Wealthy Homeowner (uncredited)
- Trevor Cooper - Man in Tweed's Office (uncredited)
- Massimo Vanni - Bar Bouncer (uncredited)
- Salvatore Billa - Native (uncredited)
- Marcello Fonte - Citizen (uncredited)
- Vincenzo Tanassi - Fireman (uncredited)
- Paolo Lorimer - Tammany Man (uncredited)
- Michele Bevilacqua - Middle Class Man (uncredited)
- Franco Venditti - Coach (uncredited)
- Katy Monique Cuomo - Tweed's Whore (uncredited)
- Pietro Torrisi - Priest's Gang Member (uncredited)
- Corrado Scalia - Rapist (uncredited)
- Loretta Rossi Stuart - Dead Rabbit Gang Member (uncredited)
- Mauro Cremonini - Internee (uncredited)
- Ottaviano Dell'Acqua - Bill the Butcher's Gang Member (uncredited)
- Arnaldo Dell'Acqua - Bill the Butcher's Gang Member (uncredited)
- Alberto Dell'Acqua - Bill the Butcher's Gang Member (uncredited)
- Franco Daddi - Bill the Butcher's Gang Member (uncredited)
- Virgilio Ponti - Bill the Butcher's Gang Member (uncredited)
- Clemente Ukmar - Priest's Gang Member (uncredited)
- Patrizio Pelizzi - Italian migrants
-
anonymous
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