- Livio Lorenzon - Baker
- Sandro Scarchilli - Tuco Henchman
- Benito Stefanelli - Member of Angel Eyes' Gang
- Angelo Novi - Monk
- Antonio Casas - Stevens
- Aldo Sambrell - Member of Angel Eyes' Gang
- Al Mulock - One-Armed Bounty Hunter
- Sergio Mendizábal - Blonde Bounty Hunter
- Antonio Molino Rojo - Captain Harper
- Lorenzo Robledo - Clem
- Mario Brega - Corporal Wallace
- Chelo Alonso - Stevens' Wife (uncredited)
- Fortunato Arena - 1st Sombrero Onlooker at Tuco's 1st Hanging (uncredited)
- Román Ariznavarreta - Bounty Hunter (uncredited)
- Silvana Bacci - Mexican Woman with Blondie (uncredited)
- Joseph Bradley - Old Soldier (uncredited)
- Frank Braña - Bounty Hunter #2 (uncredited)
- Amerigo Castrighella - 2nd Sombrero Onlooker at Tuco's 1st Hanging (uncredited)
- Saturno Cerra - Bounty Hunter (uncredited)
- William Conroy - Confederate Soldier (uncredited)
- Axel Darna - Dying Confederate Soldier (uncredited)
- Tony Di Mitri - Deputy (uncredited)
- Gianni Di Segni - Deputy at 1st Hanging (uncredited)
- Alberigo Donadeo - Spectator Before Hanging (uncredited)
- Attilio Dottesio - 3rd Sombrero Onlooker at Tuco's 1st Hanging (uncredited)
- Luis Fernández de Eribe - Soldier Coat (uncredited)
- Veriano Ginesi - Bald Onlooker at Tuco's 1st Hanging (uncredited)
- Jesús Guzmán - Pardue the Hotel Owner (uncredited)
- Víctor Israel - Sergeant at Confederate Fort (uncredited)
- Nazzareno Natale - Mexican Bounty Hunter (uncredited)
- Ricardo Palacios - Barista a Socorro (uncredited)
- Antonio Palombi - Old Sergeant (uncredited)
- Romano Puppo - Member of Angel Eyes' Gang (uncredited)
- Antoñito Ruiz - Stevens' Youngest Son (uncredited)
- Aysanoa Runachagua - Pistolero Recruited by Tuco in the Cave (uncredited)
- Enrique Santiago - Mexican Bounty Hunter (uncredited)
- José Terrón - Thomas 'Shorty' Larson (uncredited)
- Franco Tocci - Union Soldier with Cigar (uncredited)
- Antonio Montoya - Mexican Bounty Hunter (uncredited)
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