- Scott Caan - Turk Malloy
- Eddie Jemison - Livingston Dell
- Shaobo Qin - Yen
- Carl Reiner - Saul Bloom
- Elliott Gould - Reuben Tishkoff
- Eddie Izzard - Roman Nagel
- Vincent Cassel - François Toulour
- Bob Einstein - Agent Robert "Robby" Caldwell
- Olga Sosnovska - Debbie
- David Paymer - V.U.P.
- Angel Oquendo - Guard Ortega
- Julian Sands - Greco Montgomery
- Michael Mantell - Dr. Stan
- Ray Xifo - Reuben's Butler
- Soledad St. Hilaire - Chamber Maid
- Adam Lazarre-White - Bank's Junior Executive
- Maggie Rowe - Florist
- Kris Kane - Fired Waitress
- Luis Chávez - Nestor / Nestor's Brother
- Ivar Brogger - Shuffle Royale VP
- Alex Procopio - Polygrapher
- Armen Weitzman - Eugene
- Noureen DeWulf - 'Nuff Said Expo Girl
- Don McManus - Neil
- Jon Wellner - Bellman
- Mesan Richardson - Hotel Staff
- Adrian Neil - Maitre D'
- Michael Miranda - Randall
- Oprah Winfrey - Oprah Winfrey
- Bernie Yuman - Bernie Yuman
- Wayne Pére - Fireworks Guy
- Joe Chrest - Fender Roads' Manager
- Tim Conlon - Agent Caldwell's Deputy
- Moira Squier - Agent Caldwell's Deputy
- Michi Yamato - Singing Referee
- Bayanbat Davaadalai - Bayanbat Davaadalai
- Ulambayaryn Byambajav - Byambajav Ulambayar
- Ren Urano - Sumo Referee
- Musashimaru - Musashimaru
- Akebono Tarō - Tarô Akebono
- Michael Harney - Blackjack Pit Boss
- James DuMont - Security Supervisor
- Doug Purcell - Slot Machine Pit Boss
- Ashlee Vingle - Cartwheel Girl
- Andrea Tiede - Cartwheel Girl
- Margaret Travolta - Bank's Secretary
- Jacquie Barnbrook - Slot Machine Winner
- Tommy Hinkley - Roulette Dealer
- Adam Kaiz - Security Technician
- Kasey Mahaffy - Security Technician
- Nick Puga - Security Technician
- Paull Walia - Security Technician
- Mike Meldman - Mike Meldman
- Scott L. Schwartz - Bruiser
- Jorge Luis Abreu - Floor Manager
- Shae Wilson - Ticket Agent
- Kari Hawker-Diaz - High Roller (uncredited)
- Amber Hay - Cocktail Waitress (uncredited)
- Nancy Stelle - Cocktail Waitress (uncredited)
- Bonnie Joy Ashley - High Roller (uncredited)
- Yuki Bird - Casino Gambler (uncredited)
- Paul X. Campanella - Reporter (uncredited)
- Nicole Chauvet - Upscale Gambler (uncredited)
- Jaden Christopher - High Roller (uncredited)
- Natalie Cohen - Cocktail Waitress (uncredited)
- Gregor Collins - Stickman (voice) (uncredited)
- Rachel Ann Courtney - Gambler at Roulette Table (uncredited)
- Jeffrey Crisp - Casino Guest (uncredited)
- Mark Casimir Dyniewicz Jr. - Willie Bank's Hotel Guest (uncredited)
- Jason Anthony Fisher - Casino Patron (uncredited)
- Gillian Foreman - Cocktail Waitress (uncredited)
- Leslie Garza - Casino Winner (uncredited)
- James Markham Hall Jr. - High Roller (uncredited)
- Lanette Fugit Hannah - High Roller (uncredited)
- Ty Izquierdo - Bartender (uncredited)
- Shane Warren Jones - Casino Valet (uncredited)
- Christopher Jude - Conventioneer (uncredited)
- Dan Kalbfleisch - Sumo Wrestler (uncredited)
- James Martin Kelly - Craps Pit Boss (uncredited)
- Matt Kohler - High Roller (uncredited)
- Sean R. Lake - Bellman (uncredited)
- Jonathan Lane - Gambler (uncredited)
- Julio Leal - High Roller (uncredited)
- Pui Fan Lee - Las Vegas Showgirl (uncredited)
- Lauchlin MacDonald - High Roller (uncredited)
- John C. McDonnell - Stickman (uncredited)
- Jenny Morgan - Gambler (uncredited)
- Cristina Nardozzi - Cocktail Waitress (uncredited)
- Dalila Orozco - Gambler (uncredited)
- Sarah Ospina - Restaurant Patron (uncredited)
- Evelina Pereira - Informer (uncredited)
- Maury Rogow - High Roller (uncredited)
- Lina So - Gambler (uncredited)
- Rose Day Stuart - Yen's Entourage (uncredited)
- Joseph Sun - High Roller (uncredited)
- Alexana Thomas - Pit Boss (uncredited)
- Tyler Tuione - Sumo (uncredited)
- Maria Zambrana - Sumo Wrestling Audience (uncredited)
- Mike Zent - High Roller (uncredited)
-
Steven Soderbergh
- George Clayton Johnson
- Brian Koppelman
- David Levien
- Ryan Piers Williams
- Jerry Weintraub
- Gregory Jacobs
- Tannis Vallely
- Debra Zane
- Larry Blake
- David Holmes
- Billy Theriot
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