- Heather McComb - Diane
- Rashida Jones - Feminist
- Sharon Stone - Fran
- Regina King - Allie
- Kathy Najimy - Doctor
- Jenny O'Hara - Marge Carpenter
- Marley McClean - Maggie Hedley
- Donald Elson - Sam
- Amy Carlson - Michelle
- Lee Garlington - Georgette
- Mitchell Anderson - Arnold
- George Newbern - Tom
- Lucinda Jenney - Ella's Mommy
- Steffani Brass - Ella
- Kirk Trutner - Neighbor
- Susan Mosher - Nurse June (segment "1961")
- C.J. Bates - Nurse Murphy (segment "1961")
- Jill Brennan - Nurse Betty (segment "1961")
- Lisa Welti - Nurse Trish (segment "1961")
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Nancy Meckler
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Norma Heyman, Joyce Herlihy
Capítulo disponible en las siguientes plataformas:
