- Russell Hopton - Terry Wickett
- David Landau - State Veterinarian
- Lumsden Hare - Sir Robert Fairland
- Erville Alderson - Pioneer (uncredited)
- Ward Bond - Cop (uncredited)
- Beulah Bondi - Mrs. Tozer (uncredited)
- Florence Britton - Miss Twyford (uncredited)
- Nora Cecil - Nurse (uncredited)
- Sidney De Gray - Dr. Hesselink (uncredited)
- Cyril Delevanti - Committee Member (uncredited)
- Walter Downing - City Clerk (uncredited)
- Gibson Gowland - Committee Member (uncredited)
- Sherry Hall - Reporter (uncredited)
- Theresa Harris - Native Mother (uncredited)
- Raymond Hatton - Drunk (uncredited)
- Charlotte Henry - Pioneer Girl (uncredited)
- George Humbert - Italian Uncle (uncredited)
- DeWitt Jennings - B.W. Tozer (uncredited)
- Mike Lally - Reporter (uncredited)
- Lillian Lawrence - West Indies Townswoman at Meeting (uncredited)
- Carl M. Leviness - Ship's Passenger (uncredited)
- James A. Marcus - Old Doctor (uncredited)
- Eric Mayne - Dignitary at Luncheon (uncredited)
- Kendall McComas - Little Johnny (uncredited)
- Edmund Mortimer - Ship's Passenger (uncredited)
- John Qualen - Henry Novak (uncredited)
- Edward Reinach - Dignitary (uncredited)
- Milton Royce - Intern (uncredited)
- Harry Schultz - Bartender (uncredited)
- Pat Somerset - Ship's Officer (uncredited)
- Adele Watson - Mrs. Novak (uncredited)
- Bobby Watson - Little Neighbor (uncredited)
- Eric Wilton - Ship's Officer (uncredited)
- John Ford
- Herbert Sutch
- Sinclair Lewis
- Samuel Goldwyn
- Robert McIntyre
- Alfred Newman
- Alfred Newman
- Ray Heindorf
Ronald Colman hace el papel de Dr. Martin Arrowsmith.
Helen Hayes interpreta a Leora Tozer Arrowsmith en la película.
Richard Bennett hace el papel de Gustav Sondelius.
Clarence Brooks interpreta a Dr. Oliver Marchand en la película.
Alec B. Francis interpreta a Twyford en la película.
Claude King interpreta a Dr. Tubbs en la película.
Bert Roach interpreta a Bert Tozer en la película.
Myrna Loy hace el papel de Joyce Lanyon.
Russell Hopton interpreta a Terry Wickett en la película.
David Landau interpreta a State Veterinarian en la película.
Lumsden Hare interpreta a Sir Robert Fairland en la película.
Erville Alderson interpreta a Pioneer (uncredited) en la película.
Ward Bond interpreta a Cop (uncredited) en la película.
Beulah Bondi interpreta a Mrs. Tozer (uncredited) en la película.
Florence Britton interpreta a Miss Twyford (uncredited) en la película.
Nora Cecil hace el papel de Nurse (uncredited).
Sidney De Gray interpreta a Dr. Hesselink (uncredited) en la película.
Cyril Delevanti hace el papel de Committee Member (uncredited).
Walter Downing hace el papel de City Clerk (uncredited).
Gibson Gowland interpreta a Committee Member (uncredited) en la película.
Sherry Hall interpreta a Reporter (uncredited) en la película.
Theresa Harris interpreta a Native Mother (uncredited) en la película.
Raymond Hatton interpreta a Drunk (uncredited) en la película.
Charlotte Henry hace el papel de Pioneer Girl (uncredited).
George Humbert interpreta a Italian Uncle (uncredited) en la película.
DeWitt Jennings interpreta a B.W. Tozer (uncredited) en la película.
Mike Lally interpreta a Reporter (uncredited) en la película.
Lillian Lawrence interpreta a West Indies Townswoman at Meeting (uncredited) en la película.
Carl M. Leviness hace el papel de Ship's Passenger (uncredited).
James A. Marcus hace el papel de Old Doctor (uncredited).
Eric Mayne interpreta a Dignitary at Luncheon (uncredited) en la película.
Kendall McComas interpreta a Little Johnny (uncredited) en la película.
Edmund Mortimer interpreta a Ship's Passenger (uncredited) en la película.
John Qualen interpreta a Henry Novak (uncredited) en la película.
Edward Reinach interpreta a Dignitary (uncredited) en la película.
Milton Royce hace el papel de Intern (uncredited).
Harry Schultz interpreta a Bartender (uncredited) en la película.
Pat Somerset interpreta a Ship's Officer (uncredited) en la película.
Adele Watson interpreta a Mrs. Novak (uncredited) en la película.
Bobby Watson hace el papel de Little Neighbor (uncredited).
Eric Wilton interpreta a Ship's Officer (uncredited) en la película.
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