- Russell Hopton - Terry Wickett
- David Landau - State Veterinarian
- Lumsden Hare - Sir Robert Fairland
- Erville Alderson - Pioneer (uncredited)
- Beulah Bondi - Mrs. Tozer (uncredited)
- Florence Britton - Miss Twyford (uncredited)
- Nora Cecil - Nurse (uncredited)
- Sidney De Gray - Dr. Hesselink (uncredited)
- Cyril Delevanti - Committee Member (uncredited)
- Walter Downing - City Clerk (uncredited)
- Gibson Gowland - Committee Member (uncredited)
- Sherry Hall - Reporter (uncredited)
- Theresa Harris - Native Mother (uncredited)
- Raymond Hatton - Drunk (uncredited)
- Charlotte Henry - Pioneer Girl (uncredited)
- George Humbert - Italian Uncle (uncredited)
- DeWitt Jennings - B.W. Tozer (uncredited)
- Mike Lally - Reporter (uncredited)
- Lillian Lawrence - West Indies Townswoman at Meeting (uncredited)
- Carl M. Leviness - Ship's Passenger (uncredited)
- James A. Marcus - Old Doctor (uncredited)
- Eric Mayne - Dignitary at Luncheon (uncredited)
- Kendall McComas - Little Johnny (uncredited)
- Edmund Mortimer - Ship's Passenger (uncredited)
- John Qualen - Henry Novak (uncredited)
- Edward Reinach - Dignitary (uncredited)
- Harry Schultz - Bartender (uncredited)
- Pat Somerset - Ship's Officer (uncredited)
- Adele Watson - Mrs. Novak (uncredited)
- Bobby Watson - Little Neighbor (uncredited)
- Eric Wilton - Ship's Officer (uncredited)
- John Ford
- Herbert Sutch
- Sinclair Lewis
- Samuel Goldwyn
- Robert McIntyre
- Alfred Newman
- Alfred Newman
- Ray Heindorf
Ronald Colman interpreta a Dr. Martin Arrowsmith en la película.
Helen Hayes hace el papel de Leora Tozer Arrowsmith.
Richard Bennett interpreta a Gustav Sondelius en la película.
Clarence Brooks hace el papel de Dr. Oliver Marchand.
Alec B. Francis hace el papel de Twyford.
Claude King hace el papel de Dr. Tubbs.
Bert Roach interpreta a Bert Tozer en la película.
Myrna Loy hace el papel de Joyce Lanyon.
Russell Hopton interpreta a Terry Wickett en la película.
David Landau interpreta a State Veterinarian en la película.
Lumsden Hare interpreta a Sir Robert Fairland en la película.
Erville Alderson interpreta a Pioneer (uncredited) en la película.
Ward Bond interpreta a Cop (uncredited) en la película.
Beulah Bondi interpreta a Mrs. Tozer (uncredited) en la película.
Florence Britton interpreta a Miss Twyford (uncredited) en la película.
Nora Cecil hace el papel de Nurse (uncredited).
Sidney De Gray interpreta a Dr. Hesselink (uncredited) en la película.
Cyril Delevanti interpreta a Committee Member (uncredited) en la película.
Walter Downing interpreta a City Clerk (uncredited) en la película.
Gibson Gowland hace el papel de Committee Member (uncredited).
Sherry Hall hace el papel de Reporter (uncredited).
Theresa Harris interpreta a Native Mother (uncredited) en la película.
Raymond Hatton interpreta a Drunk (uncredited) en la película.
Charlotte Henry interpreta a Pioneer Girl (uncredited) en la película.
George Humbert interpreta a Italian Uncle (uncredited) en la película.
DeWitt Jennings interpreta a B.W. Tozer (uncredited) en la película.
Mike Lally hace el papel de Reporter (uncredited).
Lillian Lawrence interpreta a West Indies Townswoman at Meeting (uncredited) en la película.
Carl M. Leviness hace el papel de Ship's Passenger (uncredited).
James A. Marcus interpreta a Old Doctor (uncredited) en la película.
Eric Mayne hace el papel de Dignitary at Luncheon (uncredited).
Kendall McComas interpreta a Little Johnny (uncredited) en la película.
Edmund Mortimer interpreta a Ship's Passenger (uncredited) en la película.
John Qualen interpreta a Henry Novak (uncredited) en la película.
Edward Reinach hace el papel de Dignitary (uncredited).
Milton Royce interpreta a Intern (uncredited) en la película.
Harry Schultz hace el papel de Bartender (uncredited).
Pat Somerset interpreta a Ship's Officer (uncredited) en la película.
Adele Watson interpreta a Mrs. Novak (uncredited) en la película.
Bobby Watson interpreta a Little Neighbor (uncredited) en la película.
Eric Wilton interpreta a Ship's Officer (uncredited) en la película.
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