- Russell Hopton - Terry Wickett
- David Landau - State Veterinarian
- Lumsden Hare - Sir Robert Fairland
- Erville Alderson - Pioneer (uncredited)
- Ward Bond - Cop (uncredited)
- Beulah Bondi - Mrs. Tozer (uncredited)
- Florence Britton - Miss Twyford (uncredited)
- Nora Cecil - Nurse (uncredited)
- Sidney De Gray - Dr. Hesselink (uncredited)
- Cyril Delevanti - Committee Member (uncredited)
- Walter Downing - City Clerk (uncredited)
- Gibson Gowland - Committee Member (uncredited)
- Sherry Hall - Reporter (uncredited)
- Theresa Harris - Native Mother (uncredited)
- Raymond Hatton - Drunk (uncredited)
- Charlotte Henry - Pioneer Girl (uncredited)
- George Humbert - Italian Uncle (uncredited)
- DeWitt Jennings - B.W. Tozer (uncredited)
- Mike Lally - Reporter (uncredited)
- Lillian Lawrence - West Indies Townswoman at Meeting (uncredited)
- Carl M. Leviness - Ship's Passenger (uncredited)
- James A. Marcus - Old Doctor (uncredited)
- Eric Mayne - Dignitary at Luncheon (uncredited)
- Kendall McComas - Little Johnny (uncredited)
- Edmund Mortimer - Ship's Passenger (uncredited)
- John Qualen - Henry Novak (uncredited)
- Edward Reinach - Dignitary (uncredited)
- Milton Royce - Intern (uncredited)
- Harry Schultz - Bartender (uncredited)
- Pat Somerset - Ship's Officer (uncredited)
- Adele Watson - Mrs. Novak (uncredited)
- Bobby Watson - Little Neighbor (uncredited)
- Eric Wilton - Ship's Officer (uncredited)
- John Ford
- Herbert Sutch
- Sinclair Lewis
- Samuel Goldwyn
- Robert McIntyre
- Alfred Newman
- Alfred Newman
- Ray Heindorf
Ronald Colman interpreta a Dr. Martin Arrowsmith en la película.
Helen Hayes interpreta a Leora Tozer Arrowsmith en la película.
Richard Bennett interpreta a Gustav Sondelius en la película.
Clarence Brooks interpreta a Dr. Oliver Marchand en la película.
Alec B. Francis hace el papel de Twyford.
Claude King hace el papel de Dr. Tubbs.
Bert Roach interpreta a Bert Tozer en la película.
Myrna Loy interpreta a Joyce Lanyon en la película.
Russell Hopton hace el papel de Terry Wickett.
David Landau interpreta a State Veterinarian en la película.
Lumsden Hare interpreta a Sir Robert Fairland en la película.
Erville Alderson interpreta a Pioneer (uncredited) en la película.
Ward Bond interpreta a Cop (uncredited) en la película.
Beulah Bondi hace el papel de Mrs. Tozer (uncredited).
Florence Britton hace el papel de Miss Twyford (uncredited).
Nora Cecil interpreta a Nurse (uncredited) en la película.
Sidney De Gray interpreta a Dr. Hesselink (uncredited) en la película.
Cyril Delevanti interpreta a Committee Member (uncredited) en la película.
Walter Downing hace el papel de City Clerk (uncredited).
Gibson Gowland interpreta a Committee Member (uncredited) en la película.
Sherry Hall interpreta a Reporter (uncredited) en la película.
Theresa Harris interpreta a Native Mother (uncredited) en la película.
Raymond Hatton interpreta a Drunk (uncredited) en la película.
Charlotte Henry hace el papel de Pioneer Girl (uncredited).
George Humbert interpreta a Italian Uncle (uncredited) en la película.
DeWitt Jennings hace el papel de B.W. Tozer (uncredited).
Mike Lally hace el papel de Reporter (uncredited).
Lillian Lawrence interpreta a West Indies Townswoman at Meeting (uncredited) en la película.
Carl M. Leviness interpreta a Ship's Passenger (uncredited) en la película.
James A. Marcus hace el papel de Old Doctor (uncredited).
Eric Mayne interpreta a Dignitary at Luncheon (uncredited) en la película.
Kendall McComas interpreta a Little Johnny (uncredited) en la película.
Edmund Mortimer hace el papel de Ship's Passenger (uncredited).
John Qualen interpreta a Henry Novak (uncredited) en la película.
Edward Reinach hace el papel de Dignitary (uncredited).
Milton Royce interpreta a Intern (uncredited) en la película.
Harry Schultz interpreta a Bartender (uncredited) en la película.
Pat Somerset interpreta a Ship's Officer (uncredited) en la película.
Adele Watson hace el papel de Mrs. Novak (uncredited).
Bobby Watson interpreta a Little Neighbor (uncredited) en la película.
Eric Wilton interpreta a Ship's Officer (uncredited) en la película.
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